Patents by Inventor Xianming Deng

Xianming Deng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Type II Raf kinase inhibitors
    Patent number: 9180127
    Abstract: The present invention relates to novel compounds which are able to modulate b-raf kinases, and the use of such compounds in the treatment of various diseases, disorders or conditions.
    Type: Grant
    Filed: December 29, 2010
    Date of Patent: November 10, 2015
    Assignee: Dana-Farber Cancer Institute, Inc.
    Inventors: Nathanael S. Gray, Hwan G. Choi, Xianming Deng, Jianming Zhang
  • TYPE II RAF KINASE INHIBITORS
    Publication number: 20150157629
    Abstract: The present invention relates to novel compounds which are able to modulate b-raf kinases, and the use of such compounds in the treatment of various diseases, disorders or conditions.
    Type: Application
    Filed: November 24, 2014
    Publication date: June 11, 2015
    Applicants: Dana-Farber Cancer Institute, Inc., University of Miami
    Inventors: Nathanael Gray, Hwan Geun Choi, Xianming Deng, Jianming Zhang, Izidore Lossos
  • SMALL MOLECULE MYRISTATE INHIBITORS OF BCR-ABL AND METHODS OF USE
    Publication number: 20150094275
    Abstract: The present invention provides novel heteroaryl compounds having a pyrimidine-containing core that is linked to a 4-trifluoromethoxyphenyl group via an amine linker. Such compounds are useful for the treatment of cancers.
    Type: Application
    Filed: November 13, 2014
    Publication date: April 2, 2015
    Applicants: THE SCRIPPS RESEARCH INSTITUTE, DANA-FARBER CANCER INSTITUTE, INC.
    Inventors: Nathanael S. GRAY, Jianming ZHANG, Barun OKRAM, Xianming DENG, Jae Won CHANG, Amy WOJCIECHOWSKI
  • Indazole compounds and their uses
    Patent number: 8987275
    Abstract: The present application relates to therapeutic organic compounds, compositions comprising an effective amount of a therapeutic organic compound; and methods for treating and preventing disease comprising administering and effective amount of a therapeutic organic compound to a subject in need thereof.
    Type: Grant
    Filed: February 18, 2011
    Date of Patent: March 24, 2015
    Assignee: Dana-Farber Cancer Institute, Inc.
    Inventors: Nathanael Gray, Wenjun Zhou, Xianming Deng
  • Small molecule myristate inhibitors of BCR-ABL and methods of use
    Patent number: 8921336
    Abstract: The present invention provides novel heteroaryl compounds of formula (I) having a pyrimidine-containing core that is linked to a 4-trifluoromethoxyphenyl group via an amine linker. Such compounds are useful for the treatment of cancers.
    Type: Grant
    Filed: November 28, 2008
    Date of Patent: December 30, 2014
    Assignees: Dana-Farber Cancer Institute, Inc., The Scripps Research Institute
    Inventors: Nathanael Gray, Jianming Zhang, Barun Okram, Xianming Deng, Jae Won Chang
  • INDAZOLE COMPOUNDS AND THEIR USES
    Publication number: 20130184287
    Abstract: The present application relates to therapeutic organic compounds, compositions comprising an effective amount of a therapeutic organic compound; and methods for treating and preventing disease comprising administering and effective amount of a therapeutic organic compound to a subject in need thereof.
    Type: Application
    Filed: February 18, 2011
    Publication date: July 18, 2013
    Applicant: DANA-FARBER CANCER INSTITUTE, INC.
    Inventors: Nathanael Gray, Wenjun Zhou, Xianming Deng
  • TYPE II RAF KINASE INHIBITORS
    Publication number: 20130040949
    Abstract: The present invention relates to novel compounds which are able to modulate b-raf kinases, and the use of such compounds in the treatment of various diseases, disorders or conditions.
    Type: Application
    Filed: December 29, 2010
    Publication date: February 14, 2013
    Applicant: DANA-FARBER CANCER INSTITUTE, INC.
    Inventors: Nathanael S. Gray, Hwan G. Choi, Xianming Deng, Jianming Zhang
  • PYRIMIDO-DIAZEPINONE KINASE SCAFFOLD COMPOUNDS AND METHODS OF TREATING DISORDERS
    Publication number: 20120040961
    Abstract: The present invention relates to novel pyrimido-diazepinone compounds, methods of modulating protein kinases, including MPS1 (TTK), ERK5 (BMK1, MAPK7), polo kinase 1, 2, 3, or 4, Ack1, Ack2, AbI, DCAMKL1, ABL1, AbI mutants, DCAMKL2, ARK5, BRK, MKNK2, FGFR4, TNK1, PLK1, ULK2, PLK4, PRKD1, PRKD2, PRKD3, ROS 1, RPS6KA6, TAOK1, TAOK3, TNK2, Bcr-Abl, GAK, cSrc, TPR-Met, Tie2, MET, FGFR3, Aurora, AxI, Bmx, BTK, c-kit, CHK2, Flt3, MST2, p70S6K, PDGFR, PKB, PKC, Raf, ROCK-H, Rsk1, SGK, TrkA, TrkB and TrkC, and the use of such compounds in the treatment of various diseases, disorders or conditions.
    Type: Application
    Filed: January 6, 2010
    Publication date: February 16, 2012
    Applicant: DANA-FARBER CANCER INSTITUTE
    Inventors: Nathanael S. Gray, Xianming Deng, Nicholas Paul Kwiatkowski
  • SMALL MOLECULE MYRISTATE INHIBITORS OF BCR-ABL AND METHODS OF USE
    Publication number: 20110312908
    Abstract: The present invention provides novel heteroaryl compounds that are linked to an aryl group via an amine linker. Such compounds are useful for the treatment of cancers.
    Type: Application
    Filed: November 28, 2008
    Publication date: December 22, 2011
    Applicants: DANA-FARBER CANCER INSTITUTE, INC.
    Inventors: Nathanael S. Gray, Jianming Zhang, Barun Okram, Xianming Deng, Jae Won Chang, Amy Wojciechowski
  • Data transfer in a computing device
    Patent number: 8077644
    Abstract: A computing device includes a hardware data processing unit having at least one input buffer, a plurality of output buffers, a data transfer unit, and a software control unit, the data transfer unit configured to transfer data from the input buffer to the plurality of output buffers, and the software control unit configured to control the data transfer unit.
    Type: Grant
    Filed: July 20, 2007
    Date of Patent: December 13, 2011
    Assignee: Infineon Technologies AG
    Inventors: Jinan Lin, Xiaoning Nie, Ralf Itjeshorst, Tilman Giese, Xianming Deng, Denny Brem, Klaus Mott, Tideya Kella
  • COMPUTING DEVICE, HARDWARE DATA TRANSFER UNIT, SOFTWARE CONTROL UNIT, AND METHOD FOR PERFORMING A DATA TRANSFER IN A COMPUTING DEVICE
    Publication number: 20090022077
    Abstract: A computing device includes a hardware data processing unit having at least one input buffer, a plurality of output buffers, a data transfer unit, and a software control unit, the data transfer unit configured to transfer data from the input buffer to the plurality of output buffers, and the software control unit configured to control the data transfer unit.
    Type: Application
    Filed: July 20, 2007
    Publication date: January 22, 2009
    Applicant: INFINEON TECHNOLOGIES AG
    Inventors: Jinan LIN, Xiaoning NIE, Ralf ITJESHORST, Tilman GIESE, Xianming DENG, Denny BREM, Klaus MOTT, Tideya KELLA
  • ARRANGEMENT, METHOD AND COMPUTER PROGRAM PRODUCT FOR DISPLAYING A SEQUENCE OF DIGITAL IMAGES
    Publication number: 20080186320
    Abstract: An arrangement for displaying a sequence of digital images is described, including a chip with a first memory for storing an increment image which can be combined with a first digital image in such a way that a second digital image arises, an off-chip second memory for storing the first digital image, a combining device, which combines the first digital image and the increment image in such a way that the second digital image arises, and a display device which displays the first digital image and the second digital image.
    Type: Application
    Filed: February 6, 2008
    Publication date: August 7, 2008
    Applicant: Infineon Technologies AG
    Inventors: CARSTEN MIELENZ, XIANMING DENG