Abstract: The present invention disclosure also relates to a pharmaceutical composition that ccomprises the compound as an active ingredient.

Abstract: A quick-assembly structure includes an inserting portion and an inserting port allowing the inserting portion to be inserted, where one of the inserting portion and the inserting port is provided on the chassis, and the other one is provided on the back frame. A locking block of the inserting portion is movably arranged relative to the inserting port; and in an assembled state, a bump of the inserting portion is inserted into the inserting port along with the inserting portion, the locking block is pushed by an elastic force of an elastic member of the inserting port to enter a locking position, and at the locking position, a locking end of the locking block enters the inserting port and abuts against an abutting surface of the bump so as to restrict the inserting portion from being pulled out in a direction opposite to an inserting direction thereof.

Abstract: A quick-assembly structure includes first inserting connection structures, where each of the first inserting connection structures includes an inserting and clamping member and a groove body; each of the groove bodies includes an inserting groove and a clamping groove which are in communication with each other, the corresponding inserting and clamping member is inserted into the inserting groove in a vertical direction and then horizontally slides into the clamping groove in a first direction; and the seat cushion is further provided with elastic buckles, the chassis includes a clamping connection surface, and when the inserting and clamping members slide to predetermined positions in the clamping grooves, the elastic buckles are clamped with the clamping connection surface of the chassis in an abutting manner so as to restrict the chassis from sliding relative to the seat cushion in a direction opposite to the first direction.

Abstract: A method for calibrating an optical scanner device implemented by a calibration management apparatus, includes providing instructions to the optical scanner device to scan a calibration surface in a scan pattern based on one or more scan parameters, wherein the one or more scan parameters vary over the scan pattern. The scanning angle for each of the plurality of points in the scan pattern is computed based on an obtained image of a light source emitted from the optical scanner device at a scanning angle for a plurality of points in the scan pattern. A calibration relationship between the computed scanning angles and the corresponding scan parameters is determined for each of the plurality of points in the scan pattern.

Abstract: A method for calibrating an optical scanner device implemented by a calibration management apparatus, includes providing instructions to the optical scanner device to scan a calibration surface in a scan pattern based on one or more scan parameters, wherein the one or more scan parameters vary over the scan pattern. The scanning angle for each of the plurality of points in the scan pattern is computed based on an obtained image of a light source emitted from the optical scanner device at a scanning angle for a plurality of points in the scan pattern. A calibration relationship between the computed scanning angles and the corresponding scan parameters is determined for each of the plurality of points in the scan pattern.

Abstract: Generally, the present invention provides devices and methods for delivering high, efficacious concentrations of therapeutic agents, i.e., medicaments such as drugs, antibiotics, etc., to specific sites in a patient's body, such as tumors and infected lesions. In one aspect of the present invention there are provided devices to accomplish the aforesaid delivery of therapeutic agents and methods to accomplish the delivery by positioning a device in the body using minimally invasive techniques such as, for example, catheterization or via trochar. The devices may contain a carrier substrate and a coating on the substrate. The carrier substrate provides structural integrity to the device and the coating thereon contains at least one layer of polymeric material containing one or more medicaments. Optionally, there may be a non-medicated binder coat between the carrier substrate and the medicated polymer layer. The medicated polymer layer may contain a hydrophilic/hydrophobic polymer composition.

Abstract: The invention includes a method of coating a substrate, comprising exposing a substrate to an initiator capable of initiating a graft polymerization reaction on the substrate, to generate reactive radical sites on the surface of the substrate; contacting the substrate with a composition comprising one or more monomers in a medium which has different hydrophilicity compared to the substrate, and grafting monomer molecules onto the substrate by forming covalent bonds between monomer molecules and the substrate at reactive radical sites on the substrate surface. With the invention, novel coated articles can be obtained which are particularly useful as medical products such as catheters.

Abstract: A part that can be introduced and/or implanted in the body, in body parts, or in body cavities, made of nonmetallic material or having a nonmetallic surface is designed such that infections associated with the use of parts of this type are reduced or entirely eliminated. This is achieved due to the fact that the entire surface of this part or parts or, depending on the effect, partial areas of this part or parts, that are nevertheless not in geometric contact, is/are furnished with a metallization (6). It is also possible that the material at least in the area of its exterior surface (17) contains metallic particles (18) in powder or granular form made of a metal having an oligodynamic effect, and that the most exterior metallic particles (18) are uncovered at least partially at the surface.

Abstract: The invention includes a method of coating a substrate, comprising exposing a substrate to an initiator capable of initiating a graft polymerization reaction on the substrate, to generate reactive radical sites on the surface of the substrate; contacting the substrate with a composition comprising one or more monomers in a medium which has different hydrophilicity compared to the substrate, and grafting monomer molecules onto the substrate by forming covalent bonds between monomer molecules and the substrate at reactive radical sites on the substrate surface. With the invention, novel coated articles can be obtained which are particularly usefull as medical products such as catheters.

Abstract: Generally, the present invention provides devices and methods for delivering high, efficacious concentrations of therapeutic agents, i.e., medicaments such as drugs, antibiotics, etc., to specific sites in a patient's body, such as tumors and infected lesions. In one aspect of the present invention there are provided devices to accomplish the aforesaid delivery of therapeutic agents and methods to accomplish the delivery by positioning a device in the body using minimally invasive techniques such as, for example, catheterization or via trochar. The devices may contain a carrier substrate and a coating on the substrate. The carrier substrate provides structural integrity to the device and the coating thereon contains at least one layer of polymeric material containing one or more medicaments. Optionally, there may be a non-medicated binder coat between the carrier substrate and the medicated polymer layer. The medicated polymer layer may contain a hydrophilic/hydrophobic polymer composition.

Abstract: The adherent coating of the invention comprises a stabilizing polymer together with an active agent (a hydrophilic polymer and/or a bioactive agent) in a layer bonded to the surface of a medical device. This invention encompasses the coating liquids used for coating medical devices, methods of coating the devices, and the coated devices. The stabilizing polymer is selected to entrap the active agent in a coating that has a high degree of flexibility and has improved bonding to a wide variety of substrates. Preferred stabilizing polymers are cross-linkable acrylic and methacrylic polymers, ethylene acrylic acid copolymers, styrene acrylic copolymers, vinyl acetate polymers and copolymers, vinyl acetal polymers and copolymers, epoxy, melamine, other amino resins, phenolic polymers, copolymers thereof, and combinations.

Abstract: According to the invention, hydrating agents in ultrafine form may be incorporated in an organic coating solution with a uniform distribution that does not change due to settling. In preferred embodiments, the coating solution comprises salt dissolved in an appropriate organic solvent blend. In another embodiment, the hydrating agent may be in the form of ultrafine particles dispersed in the polymer solution. The dispersion may be obtained by adding a stream of the aqueous hydrating agent solution to the organic polymer solution in a controlled fashion, or salt particles may be formed in the polymer solution by acid-base neutralization in solution. The coating solutions are storage stable. When applied to a medical device, the coating solution produces a homogenous coating with desirable performance characteristics. The coatings of the invention adhere to the substrate but not to moist tissue with which they are placed in contact.