Patents by Inventor Xianshuang Liu

Xianshuang Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10308959
    Abstract: Some embodiments comprise methods, systems, and compositions to promote, improve and/or increase neuronal differentiation, oligodendrocyte differentiation, or neurological outcome or function in a patient in need thereof. Some embodiments also comprise the administration a composition comprising a pharmaceutically effective amount of one or more of a group comprising microRNA-146a, exosomes comprising microRNA-146a, a promoter of microRNA-146a expression, a microRNA-146a thymosin beta 4, and a phosphodiesterase 5 inhibitor to treat neurological conditions, diseases, or injuries in mammals, including in human beings.
    Type: Grant
    Filed: May 19, 2017
    Date of Patent: June 4, 2019
    Assignee: Henry Ford Health System
    Inventors: Xianshuang Liu, Zhenggang Zhang, Michael Chopp, Lei Wang, Benjamin A. L. Buller
  • Publication number: 20170321225
    Abstract: Some embodiments comprise methods, systems, and compositions to promote, improve and/or increase neuronal differentiation, oligodendrocyte differentiation, or neurological outcome or function in a patient in need thereof. Some embodiments also comprise the administration a composition comprising a pharmaceutically effective amount of one or more of a group comprising microRNA-146a, exosomes comprising microRNA-146a, a promoter of microRNA-146a expression, a microRNA-146a thymosin beta 4, and a phosphodiesterase 5 inhibitor to treat neurological conditions, diseases, or injuries in mammals, including in human beings.
    Type: Application
    Filed: May 19, 2017
    Publication date: November 9, 2017
    Inventors: Xianshuang Liu, Zhenggang Zhang, Michael Chopp, Lei Wang, Benjamin A.L. Buller
  • Patent number: 9670490
    Abstract: Some embodiments comprise methods, systems, and compositions to promote, improve and/or increase neuronal differentiation, oligodendrocyte differentiation, or neurological outcome or function in a patient in need thereof. Some embodiments also comprise the administration a composition comprising a pharmaceutically effective amount of one or more of a group comprising microRNA-146a, a promoter of microRNA-146a expression, a microRNA-146a mimic, thymosin beta 4, and a phosphodiesterase 5 inhibitor to treat neurological conditions, disease, or injury in mammals, including in human beings.
    Type: Grant
    Filed: January 22, 2014
    Date of Patent: June 6, 2017
    Assignee: Henry Ford Health System
    Inventors: Xianshuang Liu, Zhenggang Zhang, Michael Chopp, Lei Wang
  • Publication number: 20160201055
    Abstract: Some embodiments comprise methods, systems, and compositions to promote, improve and/or increase neuronal differentiation, oligodendrocyte differentiation, or neurological outcome or function in a patient in need thereof. Some embodiments also comprise the administration a composition comprising a pharmaceutically effective amount of one or more of a group comprising microRNA-146a, a promoter of microRNA-146a expression, a microRNA-146a mimic, thymosin beta 4, and a phosphodiesterase 5 inhibitor to treat neurological conditions, disease, or injury in mammals, including in human beings.
    Type: Application
    Filed: January 22, 2014
    Publication date: July 14, 2016
    Inventors: Xianshuang Liu, Zhenggang Zhang, Michael Chopp, Lei Wang, Douglas A. Hamilton, James W. Bennett, Keith Hall