Patents by Inventor Xianzhao Jia

Xianzhao Jia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TRAIL receptor-binding agents and uses of the same
    Patent number: 7897730
    Abstract: This invention relates generally to the preparation of TRAIL receptor-binding agents and uses of the same. In particular, the present invention relates to the preparation of anti-TRAIL receptor antibodies which recognize a common antigen determinant (i.e., epitope) shared by TRAIL-R1 and TRAIL-R2 receptors and their use for TRAIL receptor detection and modulation of TRAIL receptor-mediated function. The TRAIL receptor-binding agents are useful to induce apoptosis in human cancer cells. These targets may either express one or both TRAIL-R1 or TRAIL-R2. The invention provides for the use of the TRAIL receptor-binding agents of the invention in cancer therapy.
    Type: Grant
    Filed: April 29, 2007
    Date of Patent: March 1, 2011
    Assignee: Beijing Cotimes Biotech Ltd.
    Inventors: Zheng Yu, Min Zhou, Enyun Shen, Xianzhao Jia, Yang Song
  • TRAIL RECEPTOR-BINDING AGENTS AND USES OF THE SAME
    Publication number: 20090136503
    Abstract: This invention relates generally to the preparation of TRAIL receptor-binding agents and uses of the same. In particular, the present invention relates to the preparation of anti-TRAIL receptor antibodies which recognize a common antigen determinant (i.e., epitope) shared by TRAIL-R1 and TRAIL-R2 receptors and their use for TRAIL receptor detection and modulation of TRAIL receptor-mediated function. The TRAIL receptor-binding agents are useful to induce apoptosis in human cancer cells. These targets may either express one or both TRAIL-R1 or TRAIL-R2. The invention provides for the use of the TRAIL receptor-binding agents of the invention in cancer therapy.
    Type: Application
    Filed: April 29, 2007
    Publication date: May 28, 2009
    Inventors: Zheng Yu, Min Zhou, Enyun Shen, Xianzhao Jia, Yang Song