Abstract: A production method for a bispecific antibody, comprising constructing cells for producing a bispecific antibody, screening the cells, culturing the cells obtained in step one to obtain a culture solution, and performing separation and purification to obtain the bispecific antibody. The cells comprise CHO cells. The culture mode comprises fed-batch culture or perfusion culture. Various influence factors in fermentation culture and separation and purification are comprehensively analyzed, and by effective control, all factors can effectively cooperate, so that a high-purity bispecific antibody is efficiently produced, the daily output can reach 3 g/L or above, and the purity of the purified bispecific antibody can reach 90% or above. Moreover, the production process is amplified and verified, the process is stable and reliable, the cost is low, a great breakthrough is achieved compared with an existing production method.

Abstract: This application relates to a communication method and device. A remote terminal device receives a first data packet from a relay terminal device by using an SRB1. The first data packet includes a first message and an SRAP header. The remote terminal device removes the SRAP header via an SRAP entity to obtain configuration information. The SRAP entity is determined before the SRAP header is removed. The remote terminal device configures the SRAP entity based on the configuration information. The remote terminal device may predetermine the SRAP entity.

Abstract: The present disclosure relates to the technical field of optimization of charging facilities, and in particular, to a day-ahead coordinated optimization scheduling method for a truck mobile charging station.

Abstract: A method for generating a differential upgrade package, adaptable for upgrading a firmware of an embedded system with the differential upgrade package. A differential comparison is performed on an original file and a new file to generate global discrepancy information, comprising addresses and lengths of matched data portions in the new file and the original file. Thereafter, based on the global discrepancy information, the new file is divided into a plurality of blocks, with patch parameters for each of the blocks determined. Based on the patch parameters, a plurality of differential blocks are generated, respectively corresponding to each of the blocks. In the end, the differential upgrade package generation equipment combines the differential blocks into the differential upgrade package, allowing the embedded system to sequentially load each of the differential blocks from the differential upgrade package to upgrade the firmware. A differential upgrade package generation equipment is also provided.

Abstract: Disclosed is a wireless communication device including a communication circuit, a memory and a microprocessor coupled to the memory and the communication circuit. The communication circuit includes a radio frequency circuit and a first communication branch and a second communication branch sharing a frequency band and coupled to the radio frequency circuit. The memory is configured to store a network environment parameter index. The microprocessor is configured to detect a current state of a wireless network in real time based on the network environment parameter index to obtain current wireless network status data; obtain a time division multiplexing parameter according to an optimization goal and the current wireless network status data; and control the first communication branch and the second communication branch by using time division multiplexing according to the time division multiplexing parameter. Thus, spectrum and radio frequency resources can be optimally used.

Abstract: The present invention discloses a selenium-doped MXene composite nano-material and a preparation method thereof, comprising the following steps: (1) adding MXene and an organic selenium source into a dispersant, and stirring to prepare a dispersion with a concentration of 1 mg/ml to 100 mg/ml; (2) transferring the dispersion into a reaction kettle, then heating, reacting, and then naturally cooling to a room temperature; (3) washing the product obtained in the step (2) with a cleaning agent, then centrifuging to collect a precipitate, and drying the precipitate under vacuum; and (4) placing the sample obtained in the step (3) into a tubular furnace for calcination, introducing protective gas, heating, and then cooling to a room temperature to obtain the selenium-doped MXene composite nano-material. The material prepared by the present invention has high specific surface area, good electrical conductivity, cycle stability performance, rate performance and high theoretical specific capacity.

Abstract: A method for generating a differential upgrade package, adaptable for upgrading a firmware of an embedded system with the differential upgrade package. A differential comparison is performed on an original file and a new file to generate global discrepancy information, comprising addresses and lengths of matched data portions in the new file and the original file. Thereafter, based on the global discrepancy information, the new file is divided into a plurality of blocks, with patch parameters for each of the blocks determined. Based on the patch parameters, a plurality of differential blocks are generated, respectively corresponding to each of the blocks. In the end, the differential upgrade package generation equipment combines the differential blocks into the differential upgrade package, allowing the embedded system to sequentially load each of the differential blocks from the differential upgrade package to upgrade the firmware. A differential upgrade package generation equipment is also provided.

Abstract: Disclosed is a wireless communication device including a communication circuit, a memory and a microprocessor coupled to the memory and the communication circuit. The communication circuit includes a radio frequency circuit and a first communication branch and a second communication branch sharing a frequency band and coupled to the radio frequency circuit. The memory is configured to store a network environment parameter index. The microprocessor is configured to detect a current state of a wireless network in real time based on the network environment parameter index to obtain current wireless network status data; obtain a time division multiplexing parameter according to an optimization goal and the current wireless network status data; and control the first communication branch and the second communication branch by using time division multiplexing according to the time division multiplexing parameter. Thus, spectrum and radio frequency resources can be optimally used.

Abstract: The present invention discloses a selenium-doped MXene material and a preparation method thereof, comprising the following steps: (1) adding MXene and an organic selenium source into a dispersant, and stirring to prepare a dispersion with a concentration of 10 mg/ml to 100 mg/ml, wherein a mass ratio of MXene and an organic selenium source is 0.1 to 1:1; (2) transferring the dispersion into a reaction kettle, heating to 110° C. to 230° C., reacting for 10 h to 30 h, and then naturally cooling to a room temperature; and (3) washing the product obtained in the step (2) with a cleaning agent, centrifuging to collect a precipitate, and drying the precipitate under vacuum to obtain the selenium-doped MXene material. The composite material prepared by the present invention has high specific surface area, good electrical conductivity, cycle stability performance, rate performance and high theoretical specific capacity.

Abstract: The present invention discloses a tellurium-doped MXene composite material and a preparation method thereof, comprising the following steps: (1) adding MXene and a tellurium source into a dispersant to prepare a dispersion, and then stirring the dispersion; (2) heating the dispersion, reacting, and then cooling; (3) centrifuging the product obtained in the step (2), then washing and drying under vacuum; and (4) placing the dry product obtained in the step (3) into a corundum ark, and then transferring into a tubular furnace, heating under the protection of inert gas, retaining the temperature, and then cooling to obtain the tellurium-doped MXene composite material. The composite material prepared by the present invention can be used as a cathode of a potassium ion battery, which increases the interlamellar spacing, and optimizes an ion diffusion channel, so that the electrochemical performance of the potassium ion battery is improved.

Abstract: The present invention discloses a selenium-doped MXene material and a preparation method thereof, comprising the following steps: (1) adding MXene and an organic selenium source into a dispersant, and stirring to prepare a dispersion with a concentration of 10 mg/ml to 100 mg/ml, wherein a mass ratio of MXene and an organic selenium source is 0.1 to 1:1; (2) transferring the dispersion into a reaction kettle, heating to 110° C. to 230° C., reacting for 10 h to 30 h, and then naturally cooling to a room temperature; and (3) washing the product obtained in the step (2) with a cleaning agent, centrifuging to collect a precipitate, and drying the precipitate under vacuum to obtain the selenium-doped MXene material. The composite material prepared by the present invention has high specific surface area, good electrical conductivity, cycle stability performance, rate performance and high theoretical specific capacity.

Abstract: The present invention discloses a selenium-doped MXene composite nano-material and a preparation method thereof, comprising the following steps: (1) adding MXene and an organic selenium source into a dispersant, and stirring to prepare a dispersion with a concentration of 1 mg/ml to 100 mg/ml; (2) transferring the dispersion into a reaction kettle, then heating, reacting, and then naturally cooling to a room temperature; (3) washing the product obtained in the step (2) with a cleaning agent, then centrifuging to collect a precipitate, and drying the precipitate under vacuum; and (4) placing the sample obtained in the step (3) into a tubular furnace for calcination, introducing protective gas, heating, and then cooling to a room temperature to obtain the selenium-doped MXene composite nano-material. The material prepared by the present invention has high specific surface area, good electrical conductivity, cycle stability performance, rate performance and high theoretical specific capacity.

Abstract: The present invention discloses a tellurium-doped MXene composite material and a preparation method thereof, comprising the following steps: (1) adding MXene and a tellurium source into a dispersant to prepare a dispersion, and then stirring the dispersion; (2) heating the dispersion, reacting, and then cooling; (3) centrifuging the product obtained in the step (2), then washing and drying under vacuum; and (4) placing the dry product obtained in the step (3) into a corundum ark, and then transferring into a tubular furnace, heating under the protection of inert gas, retaining the temperature, and then cooling to obtain the tellurium-doped MXene composite material. The composite material prepared by the present invention can be used as a cathode of a potassium ion battery, which increases the interlamellar spacing, and optimizes an ion diffusion channel, so that the electrochemical performance of the potassium ion battery is improved.

Abstract: Provided are N-[(4-hydroxypiperidin-4-yl)methyl]pyridin-2(1H)-one derivatives represented by formula I, stereoisomers, pharmaceutically acceptable salts or solvates thereof. The above compounds have the dual activities of 5-hydroxytryptamine 1A receptor ligand and selective serotonin reuptake inhibitor. The preparation methods of the above compounds, the uses of these compounds for the prevention or treatment of nervous system diseases related to 5-hydroxytryptamine system dysfunction and the pharmaceutical compositions containing these compounds are also provided.

Abstract: Provided are N-[(4-hydroxypiperidin-4-yl)methyl]pyridin-2(1H)-one derivatives represented by formula I, stereoisomers, pharmaceutically acceptable salts or solvates thereof. The above compounds have the dual activities of 5-hydroxytryptamine 1A receptor ligand and selective serotonin reuptake inhibitor. The preparation methods of the above compounds, the uses of these compounds for the prevention or treatment of nervous system diseases related to 5-hydroxytryptamine system dysfunction and the pharmaceutical compositions containing these compounds are also provided.

Abstract: Disclosed is a brush having a one-piece body comprised of a handle and at one end thereof a head provided with bristles, wherein the brush body comprises a mixture of first polymer and a second polymer that is of a lesser hardness than the first polymer, wherein the ratio of the first polymer to the second polymer is from about 95:5 to about 30:70.