Patents by Inventor Xiao-Dan Yao

Xiao-Dan Yao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20110143399
    Abstract: The present invention provides a method to directionally clone any linear template DNA molecule into any linearized vector. The vector ends may be generated from any restriction enzyme cleavage. The method does not require a ligation step nor the use of carefully controlled conditions as is required with methods involving specific exonucleases alone. It has been determined that specific DNA polymerases are able to efficiently join one or more linear DNA molecules sharing ends with appropriate complementation.
    Type: Application
    Filed: July 15, 2009
    Publication date: June 16, 2011
    Applicant: University of Guelph
    Inventors: David Evans, David O. Willer, Xiao-Dan Yao
  • Patent number: 7575860
    Abstract: The present invention provides a method to directionally clone any linear template DNA molecule into any linearized vector. The vector ends may be generated from any restriction enzyme cleavage. The method does not require a ligation step nor the use of carefully controlled conditions as is required with methods involving specific exonucleases alone. It has been determined that specific DNA polymerases are able to efficiently join one or more linear DNA molecules sharing ends with appropriate complementation.
    Type: Grant
    Filed: March 7, 2001
    Date of Patent: August 18, 2009
    Inventors: David H. Evans, David O. Willer, Xiao-Dan Yao
  • Publication number: 20040014034
    Abstract: The present invention relates to methods and kits for modifying viral genomes. The method involves introducing into a host cell containing a helper virus, two or more fragments of a first viral genome, the fragments having ends that are capable of being joined together comprising as little as basepair of overlapping sequence. The helper virus is able to facilitate recombination and reactivation of the DNA fragments into active infectious virions.
    Type: Application
    Filed: June 6, 2003
    Publication date: January 22, 2004
    Inventors: David H. Evans, Xiao-Dan Yao
  • Publication number: 20030162265
    Abstract: The present invention provides a method to directionally clone any linear template DNA molecule into any linearized vector. The vector ends may be generated from any restriction enzyme cleavage. The method does not require a ligation step nor the use of carefully controlled conditions as is required with methods involving specific exonucleases alone. It has been determined that specific DNA polymerases are able to efficiently join one or more linear DNA molecules sharing ends with appropriate complementation.
    Type: Application
    Filed: January 8, 2003
    Publication date: August 28, 2003
    Inventors: David H Evans, David O Willer, Xiao-Dan Yao