Patents by Inventor Xiao-dong Qian

Xiao-dong Qian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for Measuring Real Time Kinase Activity
    Publication number: 20070196860
    Abstract: The present invention relates to methods for detecting and/or measuring the activity of a specific kinase, with the methods comprising contacting one or more kinases with a binding agent to isolate a specific kinase of interest. The isolated kinase is then contacted with a kinase activity sensor, where the kinase activity sensor is comprised of a kinase recognition motif that is capable of being recognized by the isolated kinase, and at least one phosphorylation site. The isolated kinase phosphorylates the amino acid target of the kinase activity sensor and levels of the phosphorylated target amino acid can then be quantified.
    Type: Application
    Filed: January 18, 2007
    Publication date: August 23, 2007
    Applicant: INVITROGEN CORPORATION
    Inventors: Kyle Gee, Min Li, Xiao-Dong Qian, Erik Schaefer
  • Aminobenzoxazoles as therapeutic agents
    Publication number: 20060025383
    Abstract: A compound of Formula (I), wherein the substituents are as defined herein, which are useful as kinase inhibitors.
    Type: Application
    Filed: February 3, 2005
    Publication date: February 2, 2006
    Inventors: Neil Wishart, Michael Friedman, Lee Arnold, Bryant Yang, Shannon Fix-Stenzel, Anna Ericsson, Michael Michaelides, Xiao-Dong Qian, James Holms, Douglas Steinman, Zhengping Tian, Steven Wittenberger
  • Bis-naphthalimides for the treatment of cancer
    Patent number: 5981753
    Abstract: Disclosed herein are compounds pharmaceutical compositions containing same of the formula1. A compound of the Formula ##STR1## wherein X, X', X" and X'", A, B, D, R, and R' are as identified in the specification and their preparation. Pharmaceutical compositions containing same can be used in the treatment of cancer.
    Type: Grant
    Filed: July 15, 1997
    Date of Patent: November 9, 1999
    Assignee: BASF Aktiengesellschaft
    Inventors: Gerhard Keilhauer, Cynthia Romerdahl, Miguel Fernandez Brana, Xiao-Dong Qian, Peter Bousquet, Jose Maria Castellano Berlanga, Marina Moran Moset, Maria Jesus Perez De Vega
  • Bis-naphthalimides for the treatment of cancer
    Patent number: 5789418
    Abstract: Disclosed herein are compounds pharmaceutical compositions containing same of the formula1. A compound of the Formula ##STR1## wherein X, X', X" and X'", A, B, D, R, and R' are as identified in the specification and their preparation. Pharmaceutical compositions containing same can be used in the treatment of cancer.
    Type: Grant
    Filed: February 18, 1997
    Date of Patent: August 4, 1998
    Assignee: BASF Aktiengesellschaft
    Inventors: Gerhard Keilhauer, Cynthia Romerdahl, Miguel Fernandez Brana, Xiao-Dong Qian, Peter Bousquet, Jose Maria Castellano Berlanga, Marina Moran Moset, Maria Jesus Perez De Vega
  • Bis-naphthalimides for the treatment of cancer
    Patent number: 5616589
    Abstract: Disclosed herein are compounds pharmaceutical compositions containing same of the formula1. A compound of the Formula ##STR1## wherein X, X', X" and X'", A, B, D, R, and R' are as identified in the specification and their preparation. Pharmaceutical compositions containing same can be used in the treatment of cancer.
    Type: Grant
    Filed: August 9, 1994
    Date of Patent: April 1, 1997
    Assignee: BASF Aktiengesellschaft
    Inventors: Gerhard Keilhauer, Cynthia Romerdahl, Miguel F. Bra na, Xiao-Dong Qian, Peter Bousquet, Jose M.C. Berlanga, Marina M. Moset, Maria J.P. de Vega
  • Asymmetrically substituted bisnaphthalimides
    Patent number: 5554622
    Abstract: Asymmetrically substituted bisnaphthalimides of the formula I ##STR1## in which A, B, D, R.sup.1, R.sup.2, m and have the meanings stated in the description, and the salts thereof with phsiologically tolerated acids, ale described. The novel compounds are suitable for controlling diseases.
    Type: Grant
    Filed: March 15, 1995
    Date of Patent: September 10, 1996
    Assignee: Knoll Aktiengesellschaft
    Inventors: Miguel F. Bra na, Jos e M. C. Berlanga, Marina M. Moset, Mar ia J. P erez de Vega, Gerhard Keilhauer, Xiao-Dong Qian, Cynthia Romerdahl
  • Peptides, the preparation and use thereof
    Patent number: 5502032
    Abstract: Novel peptides of the formula ##STR1## in which R.sup.1, R.sup.2, X, A, R.sup.3, B, D, E, R.sup.7, M, Q, a, b and d have the meanings stated in the description, and the preparation thereof are described. The novel substances have an antineoplastic effect.
    Type: Grant
    Filed: January 5, 1994
    Date of Patent: March 26, 1996
    Assignee: BASF Aktiengesellschaft
    Inventors: Andreas Haupt, Bernd Janssen, Kurt Ritter, Dagmar Klinge, Gerhard Keilhauer, Cynthia Romerdahl, Teresa Barlozzari, Xiao-dong Qian