Patents by Inventor Xiao DOU

Xiao DOU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190345441
    Abstract: An immortalized ?-1,3-galactosyltransferase gene knockout (GTKO) pig hepatocyte cell line, the preparation method and its application in preparing bioartificial liver and preparing medicine for treating liver failure. The immortalized GTKO pig hepatocyte cell line of this invention retains the main characteristics of the primary GTKO pig hepatocytes, including the function of urea synthesis and albumin synthesis. The cell line can be subjected to near-unlimited expansion culture in vitro, and can be used to study key molecular and drug intervention targets in xenograft rejection. When applied to bioartificial liver treatment, the immortalized GTKO pig hepatocytes can effectively solve the problem of xenogeneic hyperacute immune rejection, and reducing the use of immunosuppressive agents, prolonging the survival of transplant recipients and the time of normal liver function. Thus, the immortalized GTKO pig hepatocytes have important medical application prospects.
    Type: Application
    Filed: July 4, 2019
    Publication date: November 14, 2019
    Inventors: Kefeng DOU, Xiao LI
  • Patent number: 10350568
    Abstract: A membrane-forming composition, soft and hard capsules prepared based on the composition and the preparation methods are described. The membrane-forming composition includes pullulan polysaccharide, gellan gum, amino acid moisturizing agent, anti-hygroscopic agent and so on. It is suitable for the fabrication of hard or soft capsules. The membrane-forming composition can gelate without alkali metal ions. It has a high moisture retention rate which makes it not easy to take up moisture and turn soft in high humid environment, and it will not turn yellow during long time storage. Furthermore, the membrane-forming composition is made up of pure natural materials.
    Type: Grant
    Filed: August 2, 2016
    Date of Patent: July 16, 2019
    Assignee: JIANGSU LEFAN CAPSULE CO., LTD.
    Inventors: Peiyong Liu, Peng Lei, Li Wang, Xiao Dou, Xudong Zhu, Yichi Zhang
  • Publication number: 20180154327
    Abstract: A membrane-forming composition, soft and hard capsules prepared based on the composition and the preparation methods are described. The membrane-forming composition includes pullulan polysaccharide, gellan gum, amino acid moisturizing agent, anti-hygroscopic agent and so on. It is suitable for the fabrication of hard or soft capsules. The membrane-forming composition can gelate without alkali metal ions. It has a high moisture retention rate which makes it not easy to take up moisture and turn soft in high humid environment, and it will not turn yellow during long time storage. Furthermore, the membrane-forming composition is made up of pure natural materials.
    Type: Application
    Filed: August 2, 2016
    Publication date: June 7, 2018
    Applicant: JIANGSU LEFAN CAPSULE CO., LTD.
    Inventors: Peiyong LIU, Peng LEI, Li WANG, Xiao DOU, Xudong ZHU, Yichi ZHANG