Abstract: Provided is a set of viral vectors, comprising: a first viral vector that carries a first nucleic acid molecule encoding an envelope protein, and a second viral vector that carries a second nucleic acid molecule encoding a fusion protein, the fusion protein comprising: a single-chain antibody capable of binding to CD28 or CD3, and a C-terminal domain, comprising a transmembrane region and an intracellular region, of the envelope protein. The C terminal of the single-chain antibody is connected to the N terminal of the C-terminal domain of the envelope protein, and the envelope protein and the fusion protein are in a non-fusion form. Also provided are a method for obtaining a lentivirus and an obtained lentivirus, a method for introducing a lentivirus into an unactivated T lymphocyte, a method for expressing a target gene, a method for obtaining a CAR-T cell and an obtained CAR-T cell, a pharmaceutical composition, and a use thereof.

Abstract: A construction method for a radiation-proof concrete hole reserved split bolt includes: 1) mounting a hole reserved sleeve; 2) mounting an inclined recoverable split bolt; 3) mounting an inclined split bolt; 4) fixing the inclined recoverable split bolt and an inclined split bolt main body; 5) pouring concrete, and dismantling related components; 6) plugging the inclined split bolt main body; and 7) plugging the hole reserved sleeve. According to the construction method, the hole reserved sleeve is obliquely arranged, the inner side of the hole reserved sleeve is sprayed with a radiation-proof coating with the functions of reducing radiation ray reflection and absorbing certain radiation rays, and in addition, after the construction of a pipeline or a line in the hole reserved sleeve is finished, the openings at both ends of the hole reserved sleeve are plugged with a radiation-proof mortar incorporated with a micro-expanding agent and a waterproof agent.

Abstract: A managing device, a method and a non-transitory computer-readable storage medium are provided for screen time management. The managing device collects screen time data from each of one or more managed devices, and stores the screen time data, the one or more managed devices being managed by the managing device. The managing device calculates overall screen usage time based on the screen time data across a desired subset of the one or more managed device. In response to a screen usage time query, The managing device provides the calculated overall screen usage time to a querying device.

Abstract: A method and system for fish identification based on body surface texture features and geometric features are provided. The method employs an improved Resnet network and a deep learning Yolov8 network to extract body surface texture features and geometric features of a fish on the basis of considering influences of fish tail swing and an oxygen concentration on a fish body form based on a small sample learning framework, and then realizes identity recognition of a fish individual by coupled analysis of the body surface texture features and the geometric features. The method can realize high-accuracy fish identification with few training samples of a fish to be identified from the perspective of actual application, provides theoretical basis and technical support for accurate fish stock assessment and accurate estimation of industrially farmed fish biomass, and meets the development requirements of modern agriculture.

Abstract: A vacuum insulation panel application device and method are provided. The device comprises a conveying platform for conveying a refrigerator housing, a foaming material spray gun head, a vacuum insulation panel placer and a press-fitter for pasting a vacuum insulation panel onto the refrigerator housing, wherein the foaming material spray gun head, the vacuum insulation panel placer and the press-fitter are sequentially arranged in the moving direction of the conveying platform; the spray gun head is fixedly arranged beside the conveying platform; and the press-fitter is provided with rollers for rolling the vacuum insulation panel.

Abstract: The embodiments of the disclosure provide a method, apparatus, device and storage medium for presenting information, which relate to the technical field of computers. The method includes: obtaining object search information, in response to the object search information being object category information, determining a target object category corresponding to the object search information, and presenting object information of a plurality of target objects corresponding to the target object category in a search result presentation page; where all the plurality of target objects are different, and object information of a target object includes object attribute information and image resource information of the target object. By employing the above technical solution, when the user is searching the object category, object information of a plurality of target objects different from each other corresponding to the target object category is presented in the search result page.

Abstract: Provided are an endovascular-stent-based electrode array, a method for manufacturing the same, and an electrical stimulation system. The endovascular-stent-based electrode array includes a stent woven from stent woven wires. The stent woven wires include at least one first metal woven wire, each respective first metal woven wire includes an insulated segment and a conductive segment axially arranged, the insulated segment is electrically insulated from other stent woven wires and a human tissue, and the conductive segment is configured to perform at least one of: delivering a stimulation pulse to a nerve surrounding the human tissue, and sensing an electrical signal from the nerve surrounding the human tissue. A proximal end of the respective first metal woven wire is configured to be electrically connected to an external device, and a distal terminal end of the respective first metal woven wire is electrically insulated from the human tissue.

Abstract: An inner and outer tank connection device for a cryogenic storage tank includes a suspension belt; a first connection assembly for connecting the outer tank, wherein the first connection assembly includes a first connection seat and a first connection member, and the first connection seat is configured for connecting the outer tank and the first connection seat is provided with a first limiting seat, the first connection member is rotatably connected to one end of the suspension belt, and the first connection member is provided with a first limiting portion, and the first limiting portion fits with the first limiting seat to limit the first connection member from twisting on the first connection seat with the suspension belt as a rotation axis; and a second connection assembly for connecting the inner tank, wherein the second connection assembly is rotatably connected to another end of the suspension belt.

Abstract: A graphite composite negative electrode material, a preparation method therefor and an application thereof. A coating layer formed by mixing a plurality of substances is coated on the surface of graphite, the high theoretical specific capacity of titanium niobate is utilized, and carbon nanotubes and amorphous carbon are added in an auxiliary manner, the carbon nanotubes form a network structure, and the amorphous carbon stabilizes the structure of the material, which jointly improve the structural stability of the material in the charging and discharging process, and improve the first efficiency and the cycle performance of the material.

Abstract: The present disclosure generally relates to methods and user interfaces for authentication, including providing authentication at a computer system in accordance with some embodiments.

Abstract: The present invention relates to a high temperature heat exchange and heat storage unit, and mechanism and device thereof. The high temperature heat exchange and heat storage unit comprises a housing containing a plurality of solid heat storage particles. The housing has a fluid inlet on the top of the housing, and has a plurality of fluid outlets on the bottom of the housing; a plurality of overflow ports, a plurality of overflow pipes, and a heat exchange pipe is disposed inside the housing; each overflow pipe communicates with one corresponding overflow port and one corresponding fluid outlet of the housing, and a highest point of each overflow pipe is lower than the top of the housing. No sealing structure needs to be disposed at the fluid inlet of the housing, so that the high temperature heat exchange and heat storage unit is simple in structure.

Abstract: A wafer cleaning apparatus provided by the present invention comprises a rotary shaft, a chuck arranged on the top of the rotary shaft for retaining the wafer, a fixed shaft coaxially passed through the rotary shaft, and an upper end cover and a lower end cover that block the top and bottom of the fixed shaft respectively. Wherein, the fixed shaft is a hollow shaft with at least one circle of exhaust holes provided on the wall of the fixed shaft. The lower end cover is arranged with a gas inlet port, through which a protective gas is provided to the interior of the fixed shaft. The protective gas forms a positive pressure in the annular space between the fixed shaft and the rotary shaft through the at least one circle of exhaust holes. The present invention provides positive pressure protective gas to the spacing between the fixed shaft and the rotary shaft by opening exhaust holes on the wall of the fixed shaft.

Abstract: Disclosed is an IL-15 mutant fusion protein preparation. Specifically, provided is an IL-15 mutant fusion protein pharmaceutical composition. The composition comprises an IL-15 mutant fusion protein, a buffer solution, a protein stabilizer and a surfactant. The pharmaceutical composition can maintain the stability of the IL-15 mutant fusion protein in the long-term storage and transportation process of the product, and thus, the stability, safety and effectiveness of the drug are ensured.

Abstract: The present invention relates to a high temperature heat exchange and heat storage unit, and mechanism and device thereof. The high temperature heat exchange and heat storage unit comprises a housing containing a plurality of solid heat storage particles. The housing has a fluid inlet on the top of the housing, and has a plurality of fluid outlets on the bottom of the housing; a plurality of overflow ports, a plurality of overflow pipes, and a heat exchange pipe is disposed inside the housing; each overflow pipe communicates with one corresponding overflow port and one corresponding fluid outlet of the housing, and a highest point of each overflow pipe is lower than the top of the housing. No sealing structure needs to be disposed at the fluid inlet of the housing, so that the high temperature heat exchange and heat storage unit is simple in structure.

Abstract: A graphite composite negative electrode material, a preparation method therefor and an application thereof. A coating layer formed by mixing a plurality of substances is coated on the surface of graphite, the high theoretical specific capacity of titanium niobate is utilized, and carbon nanotubes and amorphous carbon are added in an auxiliary manner, the carbon nanotubes form a network structure, and the amorphous carbon stabilizes the structure of the material, which jointly improve the structural stability of the material in the charging and discharging process, and improve the first efficiency and the cycle performance of the material.

Abstract: Provided are a thermal barrier coating and a preparation method thereof, which belong to the field of coating technology. The thermal barrier coating has a double-layer coating structure, and includes an intermediate layer attached to a surface of a metal bonding layer, and a top layer, wherein the intermediate layer is formed by atmospheric plasma spraying YSZ porous microspheres, and the top layer is formed by atmospheric plasma spraying Yb—Gd codoped YSZ porous microspheres; the intermediate layer is in contact with the surface of the metal bonding layer, and the top layer is directly exposed to a high-temperature gas environment.

Abstract: The present disclosure relates to a bispecific antibody capable of specifically binding PVRIG and TIGIT, which can modulate the function of immune cells and can be used as a drug to treat diseases related to immune abnormalities, such as tumors.

Abstract: A compound as represented by formula (I) or a pharmaceutically acceptable salt thereof or a pharmaceutical composition thereof, a preparation method therefor, and the use thereof in the treatment of tumors, inflammatory diseases or autoimmune diseases.

Abstract: The invention relates to a self-resetting buckling-restrained brace, comprising a central positioning plate and secondary buckling-restrained units located on the left and right sides; the secondary buckling-restrained units each comprise a connection node, a brace core component, an outer sleeve steel pipe, a sliding load-bearing plate, a fixed load-bearing plate, a stabilization steel bar, steel frame braces, a Belleville spring and friction plates; the brace core component, the sliding load-bearing plate and the stabilization steel bar are connected in order and slide into the outer sleeve steel pipe; the middle portion of the brace core component penetrates through the outer sleeve steel pipe, and the outer end of the brace core component is fixedly connected to the connection node; the fixed load-bearing plate, the steel frame braces and the central positioning plate are connected in order, and an inner end of the stabilization steel bar penetrates through the fixed load-bearing plate; the friction plate

Abstract: The present application provides a rotation shaft mechanism for a foldable screen, a foldable screen assembly, and a foldable mobile terminal. The present application can make the foldable screen of the foldable terminal work more reliably and smoothly. It has outstanding advantages of simpler structure, easy implementation, low cost, strong reliability, long lifespan, and more application fields, and can be widely used in foldable mobile terminals.