Patents by Inventor XIAO-HAN TANG

XIAO-HAN TANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240390334
    Abstract: Specifically, the invention relates to compositions and methods for treating liver ailments, such as compositions and methods for attenuating or ameliorating the development of alcoholic liver disease (ALD), hepatic steatosis, liver oxidative stress and/or hepatic lipogenesis associated with alcohol consumption in a subject by administering a retinoic acid receptor-beta (RAR?) agonist.
    Type: Application
    Filed: September 14, 2022
    Publication date: November 28, 2024
    Applicants: Research Foundation of the City University of New York, Cornell University
    Inventors: STEVEN TRASINO, LORRAINE GUDAS, XIAO-HAN TANG, MARTA MELIS
  • Publication number: 20220347163
    Abstract: The invention provides compositions and methods for providing a cardioprotective effect in a subject. Specifically, the invention relates to compositions and methods for treating cardiovascular ailments, such as compositions and methods for attenuating or ameliorating the development of cardiac contractile dysfunction, myocardial fibrosis or maladaptive remodeling in a subject having or having had a myocardial infarction (MI) or at risk of having a myocardial infarction by administering a retinoic acid receptor-beta (RAR?) agonist.
    Type: Application
    Filed: June 30, 2022
    Publication date: November 3, 2022
    Applicants: CORNELL UNIVERSITY, ALBERT EINSTEIN COLLEGE OF MEDICINE
    Inventors: Lorraine J. GUDAS, Xiao-Han Tang, Roberto Levi, Jessica Gambardella, Gaetano Santulli
  • Publication number: 20220304945
    Abstract: This invention relates to pharmaceutical compositions and methods for treating (including managing) or preventing metabolic syndrome related conditions using one or more RAR? (e.g., RAR?2) agonists. Such conditions include, but are not limited to, diseases in pancreas, liver, kidney, testes, muscle, or adipose tissue, as well as other organs that are associated with high fat diet and/or vitamin A deficiency, as well as other conditions associated with abnormal level of triglyceride, cholesterol and/or glucose.
    Type: Application
    Filed: November 1, 2021
    Publication date: September 29, 2022
    Applicant: Cornell University
    Inventors: Lorraine J GUDAS, Yannick BENOIT, Ronald PEREZ, Xiao-Han TANG, Steven TRASINO
  • Publication number: 20220296579
    Abstract: The invention provides compositions and methods for providing a cardioprotective effect in a subject. Specifically, the invention provides compositions and methods for treating cardiovascular ailments, for example, ischemia/reperfusion (I/R) injury, cardiac arrhythmias, oxidative stress, or cardiac failure by administering a retinoic acid receptor-beta (RAR?) agonist.
    Type: Application
    Filed: December 6, 2021
    Publication date: September 22, 2022
    Applicant: CORNELL UNIVERSITY
    Inventors: Lorraine J. Gudas, Xiao-Han Tang
  • Patent number: 11207277
    Abstract: This invention relates to pharmaceutical composition and methods of using vitamin A and/or RAR? agonist for the treatment or prevention of diseases or conditions associated with high fat diet and/or vitamin deficiency.
    Type: Grant
    Filed: November 8, 2019
    Date of Patent: December 28, 2021
    Assignee: CORNELL UNIVERISITY
    Inventors: Lorraine J Gudas, Yannick Benoit, Ronald Perez, Xiao-Han Tang, Steven Trasino
  • Patent number: 11191755
    Abstract: The invention provides compositions and methods for providing a cardioprotective effect in a subject. Specifically, the invention provides compositions and methods for treating cardiovascular ailments, for example, ischemia/reperfusion (I/R) injury, cardiac arrhythmias, oxidative stress, or cardiac failure by administering a retinoic acid receptor-beta (RAR?) agonist.
    Type: Grant
    Filed: June 14, 2018
    Date of Patent: December 7, 2021
    Assignee: Cornell University
    Inventors: Lorraine J Gudas, Xiao-Han Tang
  • Patent number: 11160769
    Abstract: This invention relates to pharmaceutical compositions and methods for treating (including managing) or preventing metabolic syndrome related conditions using one or more RAR e.g., RAR agonists. Such conditions include, but are not limited to, diseases in pancreas, liver, kidney, testes, muscle, or adipose tissue, as well as other organs that are associated with high fat diet and/or vitamin A deficiency, as well as other conditions associated with abnormal level of triglyceride, cholesterol and/or glucose.
    Type: Grant
    Filed: January 16, 2015
    Date of Patent: November 2, 2021
    Assignee: Cornell University
    Inventors: Lorraine J Gudas, Yannick Benoit, Ronald Perez, Xiao-Han Tang, Steven Trasino
  • Publication number: 20200179317
    Abstract: This invention relates to pharmaceutical composition and methods of using RXR agonist and/or RAR agonist for the treatment or prevention of head and neck cancer.
    Type: Application
    Filed: November 20, 2019
    Publication date: June 11, 2020
    Applicant: Cornell University
    Inventors: LORRAINE J. GUDAS, XIAO-HAN TANG, KWAME OSEI-SARFO, ALISON URVALEK
  • Publication number: 20200078318
    Abstract: This invention relates to pharmaceutical composition and methods of using vitamin A and/or RAR? agonist for the treatment or prevention of diseases or conditions associated with high fat diet and/or vitamin deficiency.
    Type: Application
    Filed: November 8, 2019
    Publication date: March 12, 2020
    Inventors: Lorraine J Gudas, Yannick Benoit, Ronald Perez, Xiao-Han Tang, Steven Trasino
  • Patent number: 10525019
    Abstract: This invention relates to pharmaceutical composition and methods of using vitamin A and/or RAR? agonist for the treatment or prevention of diseases or conditions associated with high fat diet and/or vitamin deficiency.
    Type: Grant
    Filed: June 5, 2018
    Date of Patent: January 7, 2020
    Assignee: CORNELL UNIVERSITY
    Inventors: Lorraine J Gudas, Yannick Benoit, Ronald Perez, Xiao-Han Tang, Steven Trasino
  • Patent number: 10265378
    Abstract: This invention relates to pharmaceutical composition and methods of using RXR agonist and/or RAR agonist for the treatment or prevention of head and neck cancer.
    Type: Grant
    Filed: March 9, 2015
    Date of Patent: April 23, 2019
    Assignee: CORNELL UNIVERSITY
    Inventors: Lorraine J Gudas, Xiao-Han Tang, Kwame Osei-Sarfo, Alison Urvalek
  • Publication number: 20190029973
    Abstract: This invention relates to pharmaceutical composition and methods of using vitamin A and/or RAR? agonist for the treatment or prevention of diseases or conditions associated with high fat diet and/or vitamin deficiency.
    Type: Application
    Filed: June 5, 2018
    Publication date: January 31, 2019
    Inventors: Lorraine J. GUDAS, Yannick Benoit, Ronald Perez, Xiao-Han Tang, Steven Trasino
  • Publication number: 20180296545
    Abstract: The invention provides compositions and methods for providing a cardioprotective effect in a subject. Specifically, the invention provides compositions and methods for treating cardiovascular ailments, for example, ischemia/reperfusion (I/R) injury, cardiac arrhythmias, oxidative stress, or cardiac failure by administering a retinoic acid receptor-beta (RAR?) agonist.
    Type: Application
    Filed: June 14, 2018
    Publication date: October 18, 2018
    Inventors: LORRAINE J. GUDAS, XIAO-HAN TANG
  • Publication number: 20180263924
    Abstract: This invention relates to pharmaceutical compositions and methods for treating (including managing) or preventing metabolic syndrome related conditions using one or more RAR e.g., RAR agonists. Such conditions include, but are not limited to, diseases in pancreas, liver, kidney, testes, muscle, or adipose tissue, as well as other organs that are associated with high fat diet and/or vitamin A deficiency, as well as other conditions associated with abnormal level of triglyceride, cholesterol and/or glucose.
    Type: Application
    Filed: January 16, 2015
    Publication date: September 20, 2018
    Inventors: LORRAINE J GUDAS, YANNICK BENOIT, RONALD PEREZ, XIAO-HAN TANG, STEVEN TRASINO
  • Patent number: 10010512
    Abstract: This invention relates to pharmaceutical composition and methods of using vitamin A and/or RAR? agonist for the treatment or prevention of diseases or conditions associated with high fat diet and/or vitamin deficiency.
    Type: Grant
    Filed: January 24, 2017
    Date of Patent: July 3, 2018
    Assignee: CORNELL UNIVERSITY
    Inventors: Lorraine J Gudas, Yannick Benoit, Ronald Perez, Xiao-Han Tang, Steven Trasino
  • Publication number: 20170135964
    Abstract: This invention relates to pharmaceutical composition and methods of using vitamin A and/or RAR? agonist for the treatment or prevention of diseases or conditions associated with high fat diet and/or vitamin deficiency.
    Type: Application
    Filed: January 24, 2017
    Publication date: May 18, 2017
    Inventors: LORRAINE J GUDAS, Yannick Benoit, Ronald Perez, Xiao-Han Tang, Steven Trasino
  • Publication number: 20170072010
    Abstract: This invention relates to pharmaceutical composition and methods of using RXR agonist and/or RAR agonist for the treatment or prevention of head and neck cancer.
    Type: Application
    Filed: March 9, 2015
    Publication date: March 16, 2017
    Applicant: Cornell University
    Inventors: Lorraine J. GUDAS, Xiao-Han TANG, Kwame OSEI-SARFO, Alison URVALEK
  • Patent number: 9585857
    Abstract: This invention relates to pharmaceutical composition and methods of using vitamin A and/or RARB agonist for the treatment or prevention of diseases or conditions associated with high fat diet and/or vitamin deficiency. After smoking, high fat diet is said to be the second most lethal habit, causing 300,000 deaths each year in the U.S. alone. High fat diet leads to many health problems, including obesity, stroke, cancer, high blood pressure, diabetes, osteoarthritis, rheumatoid arthritis, multiple sclerosis, heart disease, and diseases in other organs such as liver and kidney.
    Type: Grant
    Filed: January 17, 2014
    Date of Patent: March 7, 2017
    Assignee: Cornell University
    Inventors: Lorraine J Gudas, Yannick Benoit, Ronald Perez, Xiao-Han Tang, Steven Trasino
  • Publication number: 20150352070
    Abstract: This invention relates to pharmaceutical composition and methods of using vitamin A and/or RARB agonist for the treatment or prevention of diseases or conditions associated with high fat diet and/or vitamin deficiency. After smoking, high fat diet is said to be the second most lethal habit, causing 300,000 deaths each year in the U.S. alone. High fat diet leads to many health problems, including obesity, stroke, cancer, high blood pressure, diabetes, osteoarthritis, rheumatoid arthritis, multiple sclerosis, heart disease, and diseases in other organs such as liver and kidney.
    Type: Application
    Filed: January 17, 2014
    Publication date: December 10, 2015
    Inventors: Lorraine J GUDAS, YANNICK BENOIT, RONALD PEREZ, XIAO-HAN TANG, STEVEN TRASINO