Patents by Inventor Xiao Han

Xiao Han has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10346986
    Abstract: The present disclosure relates to systems, methods, devices, and non-transitory computer-readable storage medium for segmenting three-dimensional images. In one implementation, a computer-implemented method for segmenting a three-dimensional image is provided. The method may include receiving the three-dimensional image acquired by an imaging device, and creating a first stack of two-dimensional images from a first plane of the three-dimensional image and a second stack of two-dimensional images from a second plane of the three-dimensional image. The method may further include segmenting, by a processor, the first stack and the second stack of two-dimensional images using at least one neural network model. The method may also include determining, by the processor, a label map for the three-dimensional image by aggregating the segmentation results from the first stack and second stack.
    Type: Grant
    Filed: October 16, 2018
    Date of Patent: July 9, 2019
    Assignee: Elekta, Inc.
    Inventors: Jiaofeng Xu, Xiao Han
  • Patent number: 10307108
    Abstract: Systems and methods are provided for generating a pseudo-CT prediction model that can be used to generate pseudo-CT images. An exemplary system may include a processor configured to retrieve training data including at least one MR image and at least one CT image for each of a plurality of training subjects. For each training subject, the processor may extract a plurality of features from each image point of the at least one MR image, create a feature vector for each image point based on the extracted features, and extract a CT value from each image point of the at least one CT image. The processor may also generate the pseudo-CT prediction model based on the feature vectors and the CT values of the plurality of training subjects.
    Type: Grant
    Filed: October 13, 2015
    Date of Patent: June 4, 2019
    Assignee: Elekta, Inc.
    Inventor: Xiao Han
  • Publication number: 20190133964
    Abstract: A preparation method for polypeptide nano-bubbles, comprising the following steps: constructing a recombinant plasmid, which includes a Flag tag, an adipose tissue-targeting polypeptide and the coding gene of nano-bubble marker membrane protein CD63; and transfecting the recombinant plasmid into cells which secrete nano-bubbles through lipidosome for culturing, collecting a cell culture solution, and extracting the polypeptide nano-bubbles by ultracentrifugation. The present invention further discloses the polypeptide nano-bubbles and application thereof in the preparation of drugs for treating obesity. The polypeptide nano-bubbles bring great convenience for targeted therapy of anti-obesity drugs. The polypeptide nano-bubbles have good biocompatibility and are capable of carrying different kinds of bioactive substances.
    Type: Application
    Filed: December 26, 2018
    Publication date: May 9, 2019
    Inventors: Yaqin ZHANG, Xiao HAN, Yi YUAN, Hongwei LI, Xiaoai CHANG, Jing PANG, Jingjing WANG, Bin QIAN, Heming WU, Tingting YU, Jindao WU, Ningyuan TANG, Liyong PU, Rufeng XU
  • Publication number: 20190119764
    Abstract: The present invention discloses a strain S. cerevisiae M 2016785 producing high concentration of ?-phenylethanol and application thereof, and belongs to the technical field of industrial microorganisms. The strain S. cerevisiae M 2016785 producing high concentration of ?-phenylethanol according to the present invention was deposited in China Center for Type Culture Collection (CCTCC) on Dec. 26, 2016 with the accession number OF CCTCC NO: M 2016785. The strain of the present invention has the high ?-phenylethanol production capacity, and is applied in the fermentation of Huangjiu, the fermentation of cooking wine, the brewing of vinegar, the fermentation of soybean sauce and the fermentation of Baijiu, in which the content of ?-phenylethanol can reach 410 mg/L, 450 mg/L, 300 mg/L, 200 mg/L, 110 mg/L and 370 mg/L respectively, and effectively increases the concentration of the flavor substance such as 2-phenylethyl acetate.
    Type: Application
    Filed: December 19, 2018
    Publication date: April 25, 2019
    Inventors: Jian Mao, Shuang ping Liu, Zhongwei Ji, Xiao Han
  • Publication number: 20190117998
    Abstract: The present disclosure relates to systems, methods, and computer-readable storage media for segmenting medical image. Embodiments of the present disclosure may locate and track a moving, three-dimensional (3D) target in a patient undergoing image-guided radiation therapy. For example, an adaptive filter model for a region of interest in the patient may be received, wherein the adaptive filter model is based on the target to be tracked. An image acquisition device may obtain a two-dimensional (2D) slice of a region of interest in the patient. A processor may then apply the adaptive filter model to the 2D slice, wherein the adaptive filter model includes an offset value. The processor may also determine a location of the target in the 2D slice based on the adaptive filter model. The processor may also estimate a potential location of the target based on the offset value. The processor may then repeat one or more of the above steps to track the moving target during image-guided radiation therapy of the patient.
    Type: Application
    Filed: December 12, 2018
    Publication date: April 25, 2019
    Inventors: Xiao Han, Yan Zhou
  • Patent number: 10265378
    Abstract: This invention relates to pharmaceutical composition and methods of using RXR agonist and/or RAR agonist for the treatment or prevention of head and neck cancer.
    Type: Grant
    Filed: March 9, 2015
    Date of Patent: April 23, 2019
    Assignee: CORNELL UNIVERSITY
    Inventors: Lorraine J Gudas, Xiao-Han Tang, Kwame Osei-Sarfo, Alison Urvalek
  • Publication number: 20190108635
    Abstract: Embodiments disclose a method and system for segmenting medical images. In certain embodiments, the system comprises a database configured to store a plurality of medical images acquired by an image acquisition device. The plurality of images include at least one first medical image of an object, and a second medical image of the object, each first medical image associated with a first structure label map. The system further comprises a processor that is configured to register the at least one first medical image to the second medical image, determine a classifier model using the registered first medical image and the corresponding first structure label map, and determine a second structure label map associated with the second medical image using the classifier model.
    Type: Application
    Filed: November 27, 2018
    Publication date: April 11, 2019
    Inventors: Lyndon Stanley Hibbard, Xiao Han
  • Publication number: 20190098561
    Abstract: Embodiments of this application provide an information transmission method, a network device, and a user equipment. The method provided in this application includes: sending, by a network device, a broadcast frame that includes first duration information and second duration information that are of A-BFT (Association Beamforming Training); receiving a frame sent by a first user equipment in a timeslot randomly selected from a first time range; and receiving a frame sent by a second user equipment in a timeslot randomly selected from a second time range. According to the embodiments of this application, beamforming training efficiency can be improved.
    Type: Application
    Filed: November 30, 2018
    Publication date: March 28, 2019
    Inventors: Pei ZHOU, Yan LONG, Xiao HAN, Yingpei LIN
  • Publication number: 20190098679
    Abstract: Embodiments of this application describe a communication method, a first station (STA), a second STA, and an access point (AP). The method includes: determining, by a first STA, a first basic service set (BSS) color; generating, by the first STA, a data frame when the first station STA and a second STA perform D2D transmission, where the data frame includes the first BSS color; and sending, by the first STA, the data frame to the second STA. The first BSS color is carried in the D2D data frame, so that when receiving the data frame, another receiving station in a BSS to which the first STA and the second STA belong can determine that the frame is a frame from a neighboring cell.
    Type: Application
    Filed: November 30, 2018
    Publication date: March 28, 2019
    Inventors: Meilu LIN, Xun ZHOU, Xiao HAN, Yuchen GUO, Yunbo LI
  • Publication number: 20190050992
    Abstract: The present disclosure relates to systems, methods, devices, and non-transitory computer-readable storage medium for segmenting three-dimensional images. In one implementation, a computer-implemented method for segmenting a three-dimensional image is provided. The method may include receiving the three-dimensional image acquired by an imaging device, and creating a first stack of two-dimensional images from a first plane of the three-dimensional image and a second stack of two-dimensional images from a second plane of the three-dimensional image. The method may further include segmenting, by a processor, the first stack and the second stack of two-dimensional images using at least one neural network model. The method may also include determining, by the processor, a label map for the three-dimensional image by aggregating the segmentation results from the first stack and second stack.
    Type: Application
    Filed: October 16, 2018
    Publication date: February 14, 2019
    Inventors: Jiaofeng Xu, Xiao Han
  • Publication number: 20190042885
    Abstract: Systems and methods are provided for generating a pseudo-CT prediction model using multi-channel MR images. An exemplary system may include a processor configured to retrieve training data including multiple MR images and at least one CT image for each of a plurality of training subjects. For each training subject, the processor may determine at least one tissue parameter map based on the multiple MR images and obtain CT values based on the at least one CT image. The processor may also generate the pseudo-CT prediction model based on the tissue parameter maps and the CT values of the plurality of training subjects.
    Type: Application
    Filed: September 5, 2018
    Publication date: February 7, 2019
    Inventor: Xiao Han
  • Publication number: 20190030371
    Abstract: Features, such as anatomical features, may be automatically segmented from medical imaging information, using a computer-implemented method. In an example, three-dimensional (3D) medical imaging information may be received, such as defining a first volume. A first trained convolutional neural network (CNN) may be applied to the three-dimensional medical imaging information. An output from the first trained CNN may be used to determine a region-of-interest within the first volume, the region-of-interest defining a lesser, second volume. A different, second trained CNN may be applied to the region-of-interest, a segmented representation of the 3D medical imaging information may be provided using the outputs from the first and second CNNs, where the second CNN provides enhanced segmentation detail in the region-of-interest without requiring application of the second CNN to an entirety of the first volume. Techniques are also described from training one or more of the first and second CNNs.
    Type: Application
    Filed: February 14, 2018
    Publication date: January 31, 2019
    Inventor: Xiao Han
  • Publication number: 20190029973
    Abstract: This invention relates to pharmaceutical composition and methods of using vitamin A and/or RAR? agonist for the treatment or prevention of diseases or conditions associated with high fat diet and/or vitamin deficiency.
    Type: Application
    Filed: June 5, 2018
    Publication date: January 31, 2019
    Inventors: Lorraine J. GUDAS, Yannick Benoit, Ronald Perez, Xiao-Han Tang, Steven Trasino
  • Patent number: 10190029
    Abstract: The invention relates to a polyurethane (PU) reactive hot melt adhesive removable at elevated temperature as well as having a high bonding strength at room temperature.
    Type: Grant
    Filed: December 20, 2016
    Date of Patent: January 29, 2019
    Assignee: Henkel AG & Co. KGaA
    Inventors: Uwe Franken, Claudia Meckel-Jonas, Hongxia Zhao, Yang Cao, Xiao Han
  • Patent number: 10188874
    Abstract: The present disclosure relates to systems, methods, and computer-readable storage media for segmenting medical image. Embodiments of the present disclosure may locate and track a moving, three-dimensional (3D ) target in a patient undergoing image-guided radiation therapy. For example, an adaptive filter model for a region of interest in the patient may be received, wherein the adaptive filter model is based on the target to be tracked. An image acquisition device may obtain a two-dimensional (2D) slice of a region of interest in the patient. A processor may then apply the adaptive filter model to the 2D slice, wherein the adaptive filter model includes an offset value. The processor may also determine a location of the target in the 2D slice based on the adaptive filter model. The processor may also estimate a potential location of the target based on the offset value. The processor may then repeat one or more of the above steps to track the moving target during image-guided radiation therapy of the patient.
    Type: Grant
    Filed: December 22, 2017
    Date of Patent: January 29, 2019
    Assignee: Elekta, Inc.
    Inventors: Xiao Han, Yan Zhou
  • Patent number: 10169871
    Abstract: Embodiments disclose a method and system for segmenting medical images. In certain embodiments, the system comprises a database configured to store a plurality of medical images acquired by an image acquisition device. The plurality of images include at least one first medical image of an object, and a second medical image of the object, each first medical image associated with a first structure label map. The system further comprises a processor that is configured to register the at least one first medical image to the second medical image, determine a classifier model using the registered first medical image and the corresponding first structure label map, and determine a second structure label map associated with the second medical image using the classifier model.
    Type: Grant
    Filed: December 20, 2016
    Date of Patent: January 1, 2019
    Assignee: Elekta, Inc.
    Inventors: Lyndon Stanley Hibbard, Xiao Han
  • Publication number: 20180374245
    Abstract: Systems and methods include training a deep convolutional neural network (DCNN) to reduce one or more artifacts using a projection space or an image space approach. In a projection space approach, a method can include collecting at least one artifact contaminated cone beam computed tomography (CBCT) projection space image, and at least one corresponding artifact reduced, CBCT projection space image from each patient in a group of patients, and using the artifact contaminated and artifact reduced CBCT projection space images to train a DCNN to reduce artifacts in a projection space image. In an image space approach, a method can include collecting a plurality of CBCT patient anatomical images and corresponding registered computed tomography anatomical images from a group of patients, and using the plurality of CBCT anatomical images and corresponding artifact reduced computed tomography anatomical images to train a DCNN to remove artifacts from a CBCT anatomical image.
    Type: Application
    Filed: April 27, 2018
    Publication date: December 27, 2018
    Inventors: Jiaofeng Xu, Xiao Han
  • Patent number: 10152790
    Abstract: The present disclosure relates to systems, methods, and computer-readable storage media for segmenting medical image. Embodiments of the present disclosure may locate a target in a three-dimensional (3D) volume. For example, an image acquisition device may provide a 3D medical image containing a region of interest of the target. A processor may then extract a plurality of two-dimensional (2D) slices from the 3D image. The processor may also determine a 2D patch for each 2D slice, wherein the 2D patch corresponds to an area of the 2D slice associated with the target. The processor may also convert the 2D patch to an adaptive filter model for determining a location of the region of interest.
    Type: Grant
    Filed: April 11, 2017
    Date of Patent: December 11, 2018
    Assignee: Elekta, Inc.
    Inventors: Xiao Han, Yan Zhou
  • Publication number: 20180343677
    Abstract: Embodiments of the present invention provide an information transmission method and a node. The information transmission method provided in the present invention may include: receiving, by a first node, a request message sent by a second node, where the first node and the second node belong to a same BSS; and sending, by the first node, a response message to the second node, where the response message includes an identifier of a BSS to which the first node belongs. The embodiments of the present invention can improve a network throughput.
    Type: Application
    Filed: August 1, 2018
    Publication date: November 29, 2018
    Inventors: Bo Li, Mao Yang, Xiao Han, Meilu Lin, Yuchen Guo, Xun Zhou, Yunbo Li
  • Patent number: D836692
    Type: Grant
    Filed: December 11, 2014
    Date of Patent: December 25, 2018
    Assignee: Carl Zeiss Meditec AG
    Inventors: Walter Matuschek, Xiao Han