Patents by Inventor Xiaohui Zhou
Xiaohui Zhou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12268711Abstract: Disclosed is a method for preparing a product for treating scald infection caused by Pseudomonas aeruginosa. The product includes a ferrous sulfate hydrogel, the scald is a deep second-degree scald or a third-degree scald, and a preparation process of the ferrous sulfate hydrogel includes: S1, obtaining a mixed solution by dissolving ferrous sulfate and vitamin C at a concentration ratio of 1:1 in sterile ultrapure water, heating the mixed solution to 50° C., and a concentration of the ferrous sulfate in the mixed solution being 2 mM, and S2, under a condition of heating, continuing to add sodium alginate powder whose mass constitutes 3.5% of a total mass of the mixed solution, stirring until the sodium alginate powder is dissolved and forming a stable colloid, and obtaining 2 mM of the ferrous sulfate hydrogel.Type: GrantFiled: July 19, 2024Date of Patent: April 8, 2025Assignee: NINGBO EISEN LIFE TECHNOLOGY CO., LTD.Inventors: Liangbin Hu, Haizhen Mo, Xiaohui Zhou, Hongbo Li, Dan Xu, Zhenbin Liu, Zhen Wang
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Publication number: 20250049844Abstract: Disclosed is a method for preparing a product for treating scald infection caused by Pseudomonas aeruginosa. The product includes a ferrous sulfate hydrogel, the scald is a deep second-degree scald or a third-degree scald, and a preparation process of the ferrous sulfate hydrogel includes: S1, obtaining a mixed solution by dissolving ferrous sulfate and vitamin C at a concentration ratio of 1:1 in sterile ultrapure water, heating the mixed solution to 50° C., and a concentration of the ferrous sulfate in the mixed solution being 2 mM, and S2, under a condition of heating, continuing to add sodium alginate powder whose mass constitutes 3.5% of a total mass of the mixed solution, stirring until the sodium alginate powder is dissolved and forming a stable colloid, and obtaining 2 mM of the ferrous sulfate hydrogel.Type: ApplicationFiled: July 19, 2024Publication date: February 13, 2025Applicant: NINGBO EISEN LIFE TECHNOLOGY CO., LTD.Inventors: Liangbin HU, Haizhen MO, Xiaohui ZHOU, Hongbo LI, Dan XU, Zhenbin LIU, Zhen WANG
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Publication number: 20240402188Abstract: The application belongs to the technical field of biotechnology, and specifically relates to a site-specifically labeled transmembrane protein nanodisc, and a preparation method and use thereof. The preparation method for a site-specifically labeled transmembrane domain (TMD) as provided in this disclosure involves introducing a cysteine mutation into the TMD gene of a transmembrane protein. This mutated TMD is then conjugated with a chemical compound to achieve site-specifical labeling. Subsequently, the site-specifically labeled TMD and an extracellular domain (ECD) are expressed separately. The TMD is incorporated into a nanodisc, which closely mimics the physiological environment, and then ligated to the ECD. This process results in the formation of a site-specifically labeled transmembrane protein nanodisc.Type: ApplicationFiled: May 29, 2024Publication date: December 5, 2024Inventors: Chan CAO, Junyuan GONG, Xiaohui ZHOU, Yifan LIN, Jialu GENG
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Publication number: 20240209149Abstract: A bio-based polyamide elastomer and a preparation method therefor. The bio-based polyamide elastomer is prepared using specific aliphatic diacid and pentanediamine prepared by biological methods as monomers. The polyamide elastomer of the present disclosure has excellent performance and stable monomer supply, solves the problem of excessively high cost of polyamide elastomer, expands the application scenarios of elastomers, and has high commercial value.Type: ApplicationFiled: February 21, 2024Publication date: June 27, 2024Applicants: CATHAY BIOTECH INC., CIBT AMERICA INC., CATHY (JINXIANG) BIOMATERIAL CO., LTD.Inventors: Xiaohui ZHOU, Xiucai LIU
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Patent number: 11957712Abstract: An application of a hydrogel in the preparation of products for the treatment of bacterial infection is disclosed. Ferrous ion was used in the antibacterial activity test of Staphylococcus aureus and showed a strong bactericidal effect, which the survival rate of Staphylococcus aureus is less than 0.001%, as well as the survival rate of methicillin-resistant Staphylococcus aureus (MRSA) was less than 0.01%. Ferrous ion hydrogel was used for the treatment of keratitis and skin wound infection. Ferrous ion hydrogel for the treatment of keratitis and skin wound infection, which can significantly reduce the risk of pulmonary MRSA infection, prevented the dissimilation of MRSA to the lung, and alleviated systemic inflammation in the body in a timely and effective manner, revealing the therapeutic potential of ferrous compounds for treatment of Staphylococcus aureus infections, including MRSA.Type: GrantFiled: April 19, 2023Date of Patent: April 16, 2024Assignee: SHAANXI UNIVERSITY OF SCIENCE & TECHNOLOGYInventors: Liangbin Hu, Haizhen Mo, Xiaohui Zhou, Hongbo Li, Dan Xu, Zhenbin Liu, Zhen Wang
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Publication number: 20230338418Abstract: An application of a hydrogel in the preparation of products for the treatment of bacterial infection is disclosed. Ferrous ion was used in the antibacterial activity test of Staphylococcus aureus and showed a strong bactericidal effect, which the survival rate of Staphylococcus aureus is less than 0.001%, as well as the survival rate of methicillin-resistant Staphylococcus aureus (MRSA) was less than 0.01%. Ferrous ion hydrogel was used for the treatment of keratitis and skin wound infection. Ferrous ion hydrogel for the treatment of keratitis and skin wound infection, which can significantly reduce the risk of pulmonary MRSA infection, prevented the dissimilation of MRSA to the lung, and alleviated systemic inflammation in the body in a timely and effective manner, revealing the therapeutic potential of ferrous compounds for treatment of Staphylococcus aureus infections, including MRSA.Type: ApplicationFiled: April 19, 2023Publication date: October 26, 2023Applicant: Shaanxi University of Science & TechnologyInventors: Liangbin HU, Haizhen MO, Xiaohui ZHOU, Hongbo LI, Dan XU, Zhenbin LIU, Zhen WANG
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Patent number: 11434210Abstract: A method for synthesizing valsartan, comprising the steps of: synthesizing a valsartan methyl ester intermediate to obtain a reaction mixture of the valsartan methyl ester intermediate; diluting the reaction mixture by salt water or water, and then using a first extraction solvent to extract the valsartan methyl ester intermediate; adding alkali to an organic layer containing the valsartan methyl ester intermediate for hydrolyzing, removing the organic layer, regulating pH of a water layer to be acidic by using acid, using the first extraction solvent to extract, concentrating a part of solvent, or distilling the solvent to dryness, and then adding a new solvent; finally, crystallizing, filtering, and drying to obtain the valsartan.Type: GrantFiled: July 17, 2018Date of Patent: September 6, 2022Assignee: Zhejiang Huahai Pharmaceutical Co., LtdInventors: Xiaohui Zhou, Xiaoren Zhu, Yuanxun Zhu, Peng Dong, Peng Wang, Jinsheng Lin, Wenquan Zhu, Min Li
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Patent number: 11209837Abstract: A method for generating a UAV flight trajectory. The method includes acquiring map data of a to-be-reconstructed area; the map data includes a satellite map image and a plane map image; acquiring building silhouettes of each building in a to-be-reconstructed area from a plane map image; acquiring height data of each building from a satellite map image; generating an initial model according to the building silhouettes and height data of each building; determining a view set according to an initial model; generating a flight trajectory from a view set. The initial model can be established without pre-flight of the to-be-reconstructed area, and the UAV flight trajectory can be directly generated, so that the calculation amount of data is reduced.Type: GrantFiled: October 17, 2019Date of Patent: December 28, 2021Assignee: MOUTONG SCIENCE AND TECHNOLOGY CO., LTD.Inventors: Hui Huang, Xiaohui Zhou
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Patent number: 11175289Abstract: A TRPM8 related peptide fragment, comprising amino acid sequence as shown in SEQ ID No: 1-18 is provided. Furthermore, application of TRPM8 protein, TRPM8 related peptide fragment and their antibodies in preparing diagnostic reagent for chronic prostatitis/chronic pelvic pain syndromes (CP/CPPS) is provided. By detecting level of TRPM8 protein molecule, TRPM8 related peptide fragment and their antibodies, the chronic prostatitis/chronic pelvic pain syndromes (CP/CPPS) is effectively diagnosed, and the present invention is capable of effectively making a distinction between CP/CPPS and other diseases of prostate.Type: GrantFiled: November 16, 2016Date of Patent: November 16, 2021Inventors: Lei Han, Xiaohui Zhou, Yuyan Zhou, Li Zhou, Guohua Li, Yongzhen Li
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Patent number: 11150232Abstract: A laboratory device for simulating the cement sheath consolidation in the frozen soil strata includes the main body, the pressure system and the measuring system. The main body includes the fixing plate, the detachable plate and the base plate. The circular hole is provided in the center of the base. The central column or the heat insulating casing is mounted on the base through the circular hole. The fixing plate, the detachable plate, the base plate and the central column or the heat insulating casing form a cavity for preparing the core and the cement sheath. During use, the device is placed in a low temperature context, and then the frozen soil core with a hollow cylinder can be artificially fabricated. Further, the heat insulating casing holder is placed, and the cement is added to simulate the state of the cement sheath consolidation under the actual strata conditions.Type: GrantFiled: June 28, 2019Date of Patent: October 19, 2021Assignee: CHINA UNIVERSITY OF PETROLEUM (EAST CHINA)Inventors: Xiaorong Li, Chuanliang Yan, Yang Li, Yuanfang Cheng, Zhongying Han, Benjian Song, Xiaohui Zhou
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Publication number: 20210269408Abstract: A method for synthesizing valsartan, comprising the steps of: synthesizing a valsartan methyl ester intermediate to obtain a reaction mixture of the valsartan methyl ester intermediate; diluting the reaction mixture by salt water or water, and then using a first extraction solvent to extract the valsartan methyl ester intermediate; adding alkali to an organic layer containing the valsartan methyl ester intermediate for hydrolyzing, removing the organic layer, regulating pH of a water layer to be acidic by using acid, using the first extraction solvent to extract, concentrating a part of solvent, or distilling the solvent to dryness, and then adding a new solvent; finally, crystallizing, filtering, and drying to obtain the valsartan.Type: ApplicationFiled: July 17, 2018Publication date: September 2, 2021Inventors: Xiaohui ZHOU, Xiaoren ZHU, Yuanxun ZHU, Peng DONG, Peng WANG, Jinsheng LIN, Wenquan ZHU, Min LI
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Publication number: 20210026377Abstract: A method for generating a UAV flight trajectory. The method includes acquiring map data of a to-be-reconstructed area; the map data includes a satellite map image and a plane map image; acquiring building silhouettes of each building in a to-be-reconstructed area from a plane map image; acquiring height data of each building from a satellite map image; generating an initial model according to the building silhouettes and height data of each building; determining a view set according to an initial model; generating a flight trajectory from a view set. The initial model can be established without pre-flight of the to-be-reconstructed area, and the UAV flight trajectory can be directly generated, so that the calculation amount of data is reduced.Type: ApplicationFiled: October 17, 2019Publication date: January 28, 2021Inventors: Hui HUANG, Xiaohui ZHOU
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Patent number: 10856035Abstract: A method to effectively share a message includes: establishing an association relationship between a first electronic device and a device account thereof; controlling the first electronic device to play first multimedia data by using the device account, sending an invitation link to a client corresponding to a second account; receiving, by using the device account, second message data sent by the client corresponding to the second account when the client corresponding to the second account accepts the invitation link; and sending first message data sent by a client corresponding to the first account and received by the device account and the second message data to the first electronic device, so as to display the message data on the first multimedia data.Type: GrantFiled: June 20, 2017Date of Patent: December 1, 2020Assignee: TENCENT TECHNOLOGY (SHENZHEN) COMPANY LIMITEDInventors: Zhongwei Li, Xiaohui Zhou
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Patent number: 10590377Abstract: A multi-function cooling and thermo-sensitive rack includes horizontal bars, a base, positioning holes, connectors, a lateral frame, connecting holes, a temperature-displaying prompter, and N temperature sensors. The lateral frame and the base are connected through the connectors. The lateral frame and the base have their surfaces facing each other symmetrically provided with plural connecting holes thereon. The horizontal bars have two ends thereof received in the corresponding symmetrical connecting holes. The positioning holes are distributed over the surface of the base. The N temperature sensors have output ends thereof for outputting sensing signals connected with input ends of the temperature-displaying prompter for inputting the N temperature-sensing signals. The present invention is applied to apparatuses used in microbiology experiment.Type: GrantFiled: January 29, 2018Date of Patent: March 17, 2020Assignee: HEBEI UNIVERSITY OF SCIENCE AND TECHNOLOGYInventors: Xiaohui Zhou, Le Xu, Jun Liu, Hao Liu
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Patent number: 10549870Abstract: A walking type winding machine includes a front protection ring being fixed on a steering part and a steering counting device. The steering counting device includes a first sensor for sensing the steering of a machine body, and the first sensor is connected to a controller of the walking type winding machine. The steering part includes a second sensor which is supported by an elastic component such that the second sensor is movably installed on the steering part, and the second sensor is used for sensing the backward movement of the frame of the steering part with respect to the second sensor. The walking type winding machine makes the control of a film winding path become simple and accurate, and it can protect important components of the steering part, improve walking steering sensitivity, and mitigate the impact on the machine body when colliding with an obstacle.Type: GrantFiled: October 15, 2015Date of Patent: February 4, 2020Assignee: HANGZHOU YOUNGSUN INTELLIGENT EQUIPMENT CO., LTD.Inventors: Bangyi Luo, Caiqin Zhang, Leichun Wang, Ziquan Zhang, Xiaohui Zhou, Xiaomin Ding
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Publication number: 20200003751Abstract: A laboratory device for simulating the cement sheath consolidation in the frozen soil strata includes the main body, the pressure system and the measuring system. The main body includes the fixing plate, the detachable plate and the base plate. The circular hole is provided in the center of the base. The central column or the heat insulating casing is mounted on the base through the circular hole. The fixing plate, the detachable plate, the base plate and the central column or the heat insulating casing form a cavity for preparing the core and the cement sheath. During use, the device is placed in a low temperature context, and then the frozen soil core with a hollow cylinder can be artificially fabricated. Further, the heat insulating casing holder is placed, and the cement is added to simulate the state of the cement sheath consolidation under the actual strata conditions.Type: ApplicationFiled: June 28, 2019Publication date: January 2, 2020Applicant: China University of Petroleum (East China)Inventors: Xiaorong LI, Chuanliang YAN, Yang LI, Yuanfang CHENG, Zhongying HAN, Benjian SONG, Xiaohui ZHOU
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Patent number: 10399782Abstract: The present invention provides a bottle conveyor for a filling machine, comprising multiple pairs of bottle-gripping members and a circulating chain conveyor mechanism, and a pair of bottle-gripping members is mounted, via an open-close modular mechanism, to a convey chain of the circulating chain conveyor mechanism. The open-close modular mechanism is provided with a rotary support capable of being opened as a V-shape, a synchronization mechanism configured to define the opened V-shape, an elastic mechanism configured to provide a bottle-gripping force to the bottle-gripping member and a self-restoring force for the opened V-shape, and an external force import mechanism. A mechanism configured to open the bottle-gripping members is provided respectively at a bottle entrance location and a bottle exit location of the bottle conveyor, and the mechanism configured to open the bottle-gripping members cooperates with the external force import mechanism to provide an external force.Type: GrantFiled: September 14, 2016Date of Patent: September 3, 2019Assignee: HANGZHOU YOUNGSUN INTELLIGENT EQUIPMENT CO., LTD.Inventors: Bangyi Luo, Ziquan Zhang, Leichun Wang, Xiaohui Zhou
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Patent number: 10273443Abstract: A multi-function cooling and thermo-sensitive rack includes horizontal bars, a base, positioning holes, connectors, a lateral frame, connecting holes, a temperature-displaying prompter, and N temperature sensors. The lateral frame and the base are connected through the connectors. The lateral frame and the base have their surfaces facing each other symmetrically provided with plural connecting holes thereon. The horizontal bars have two ends thereof received in the corresponding symmetrical connecting holes. The positioning holes are distributed over the surface of the base. The N temperature sensors have output ends thereof for outputting sensing signals connected with input ends of the temperature-displaying prompter for inputting the N temperature-sensing signals. The present invention is applied to apparatuses used in microbiology experiment.Type: GrantFiled: January 29, 2018Date of Patent: April 30, 2019Assignee: HEBEI UNIVERSITY OF SCIENCE AND TECHNOLOGYInventors: Xiaohui Zhou, Le Xu, Jun Liu, Hao Liu
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Publication number: 20180319598Abstract: The present invention provides a bottle conveyor for a filling machine, comprising multiple pairs of bottle-gripping members and a circulating chain conveyor mechanism, and a pair of bottle-gripping members is mounted, via an open-close modular mechanism, to a convey chain of the circulating chain conveyor mechanism. The open-close modular mechanism is provided with a rotary support capable of being opened as a V-shape, a synchronization mechanism configured to define the opened V-shape, an elastic mechanism configured to provide a bottle-gripping force to the bottle-gripping member and a self-restoring force for the opened V-shape, and an external force import mechanism. A mechanism configured to open the bottle-gripping members is provided respectively at a bottle entrance location and a bottle exit location of the bottle conveyor, and the mechanism configured to open the bottle-gripping members cooperates with the external force import mechanism to provide an external force.Type: ApplicationFiled: September 14, 2016Publication date: November 8, 2018Inventors: Bangyi LUO, Ziquan ZHANG, Leichun WANG, Xiaohui ZHOU
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Publication number: 20180194503Abstract: Disclosed is a walking type winding machine, with a front protection ring being fixed on a frame of a steering part; wherein the walking type winding machine is provided with a steering counting device, and the steering counting device is provided with a first sensor for sensing the steering of a machine body, and the first sensor is connected to a controller of the walking type winding machine, such that the controller can determine the steering times; and a second sensor is provided in the steering part, the second sensor or a component fixedly connected thereto is supported by an elastic component such that the second sensor is movably installed on the steering part, and the second sensor is used for sensing the backward movement of the frame of the steering part or the component fixedly connected to the frame with respect to the second sensor.Type: ApplicationFiled: October 15, 2015Publication date: July 12, 2018Inventors: Bangyi LUO, Caiqin ZHANG, Leichun WANG, Ziquan ZHANG, Xiaohui ZHOU, Xiaomin DING