Patents by Inventor Xiao Lan Chang

Xiao Lan Chang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HUMAN ANTI-AAV2 CAPSID POLYCLONAL ANTIBODY EPITOPES
    Publication number: 20210292370
    Abstract: Human anti-AAV capsid polyclonal antibody conformational epitopes including those of neutralizing antibodies are provided. The epitopes can be recognized by human anti-AAV2 or other AAV strain-derived capsid polyclonal antibodies. One or more of the epitopes may be mutated to form AAV2 and other AAV strain-derived capsids that can escape antibody neutralization. Methods of identifying human anti-AAV capsid polyclonal antibody conformational epitopes are also provided.
    Type: Application
    Filed: November 4, 2020
    Publication date: September 23, 2021
    Inventors: Kei Adachi, Xiao Lan Chang, Hiroyuki Nakai