Patents by Inventor Xiaonan Liu
Xiaonan Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240156917Abstract: The present invention belongs to the technical field of biomedical formulations. Provided are a temperature sensitive gel damage repair formulation and an application thereof. The formulation includes 0.01-5 mg/mL rHSA/EGF, 1.9-2.6% m/m glycine, 3.9-6.2% m/m poloxamer 188, 16.3-18.2% m/m poloxamer 407, and 0.5-100 mM phosphate buffer.Type: ApplicationFiled: July 20, 2021Publication date: May 16, 2024Inventors: Yan Fu, Dianxin Liu, Xiaonan Yang, Yusong Fu, Fang Han, Liguang Song, Jingsheng Yang, Ying Chen
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Publication number: 20240131086Abstract: The present disclosure provides use of Clostridium ghonii combined with a tumor angiogenesis inhibitor in preparing a pharmaceutical product for treating a tumor. The present disclosure further provides a drug for treating a tumor, where the drug includes active ingredients of Clostridium ghonii and a tumor angiogenesis inhibitor.Type: ApplicationFiled: October 9, 2022Publication date: April 25, 2024Inventors: Yong Wang, Yuanyuan Liu, Wenhua Zhang, Yanqiu Xing, Shaopeng Wang, Dan Wang, Hong Zhu, Xinglu Xu, Shengbiao Jiang, Xiaonan Li, Jiahui Zheng, Rong Zhang, Dongxia Yang, Yuxia Gao, Shili Shao, Ting Han
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Publication number: 20240138222Abstract: The present disclosure provides a display substrate and a display apparatus, belongs to the field of display technology, and at least partially solves one existing technical problem. The display substrate includes a base substrate, and sub-pixels in an array at intervals on the base substrate; wherein the adjacent sub-pixels are provided with a spacer region therebetween; the spacer region includes a first spacer region having a functional position, and a second spacer region having no functional position; at least some functional positions are provided with functional parts; and a width of the first spacer region between two adjacent sub-pixels arranged along the first direction or the second direction is greater than that of the second spacer region between two adjacent sub-pixels arranged along the same direction; wherein a width of the spacer region is equal to a shortest distance between boundaries of the two sub-pixels corresponding to the spacer region.Type: ApplicationFiled: August 23, 2022Publication date: April 25, 2024Inventors: Xiaonan LIU, Jun LI, Changsoon JI, Tinghua SHANG, Qian XU
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Patent number: 11964677Abstract: The present invention relates to a platform door control apparatus based on a double 2-vote-2 architecture, including a security communication and logic processing module, a driver collection module, and a maintenance module, the security communication and logic processing module is separately connected to the driver collection module and the maintenance module, and both the security communication and logic processing module and the driver collection module are devices using the double 2-vote-2 architecture. Compared with the prior art, the present invention has the following advantages of effectively improving linkage efficiency of a signal system and a platform door system, and the like.Type: GrantFiled: March 15, 2019Date of Patent: April 23, 2024Assignee: CASCO SIGNAL CO., LTD.Inventors: Ruiyuan Ye, Xiaolin Tang, Liang Chen, Zhijun Ji, Chang Liu, Chun Yang, Xiaonan Liu, Jing Xu
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Publication number: 20240115627Abstract: The present disclosure relates to use of a Clostridium ghonii spore combined with pembrolizumab in cancer treatment. It is found for the first time that the Clostridium ghonii spore combined with pembrolizumab can significantly improve a curative effect of colon cancer and reduce a dose of the pembrolizumab, and thus is efficient and low-toxic. Oncolysis by Clostridium ghonii can affect immunogenicity of a tumor microenvironment (TME) by various ways, converts an immunosuppressive state of the TME into an immune-activated state, adjusts the immunosuppressive TME, and breaks an immune tolerance. An optimal combination of the Clostridium ghonii spore and the pembrolizumab thoroughly removes about 20% of mouse tumor tissues. A benefit range of patients with tumors treated by a PD-1 antibody is expanded. The combination even has an obvious curative effect on patients failed the treatment by the PD-1 antibody.Type: ApplicationFiled: October 9, 2022Publication date: April 11, 2024Inventors: Yong Wang, Hong Zhu, Wenhua Zhang, Yanqiu Xing, Dan Wang, Yuanyuan Liu, Shaopeng Wang, Jiahui Zheng, Rong Zhang, Xiaonan Li, Xinglu Xu, Shengbiao Jiang, Lichao Xing, Yuxia Gao, Shili Shao, Ting Han
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Patent number: 11945950Abstract: The present invention provides a germ-repellent silicone rubber comprising: a silicone rubber substrate and a germ-repellent active ingredient incorporated therein; wherein, the silicone rubber substrate includes polydimethylsiloxane; the germ-repellent active ingredients include poly(ethylene oxide) and silicone oil or their derivatives. The disclosed germ-repellent silicone rubber reduces the bacterial growth by inhibiting their adherence to the surface instead of killing them, does not contribute to super bacteria formation nor cause skin irritation.Type: GrantFiled: October 22, 2021Date of Patent: April 2, 2024Assignee: Hongrita Plastics Ltd.Inventors: Xiaonan Huang, Xianqiao Liu, Chun Kit Choi
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Patent number: 11718331Abstract: The disclosure relates to a non-national standard turnout drive system based on a double 2-vote-2 architecture, including an interlocking processing subsystem IPS, an interlocking maintenance station SDM, a non-national standard turnout drive module HIOM and an interlocking maintenance station SDM, wherein the non-national standard turnout drive module HIOM, a full-electronic communication module EIOCOM2, and the interlocking processing subsystem IPS are connected with each other in order, and the full-electronic communication module EIOCOM2 is connected to the interlocking maintenance station SDM; two non-national standard turnout drive module HIOMs, which are mutually redundant, obtain turnout drive commands through the interlocking processing subsystem IPS to control drive relays in a non-national standard turnout to lift and fall for driving the turnout to rotate toward a specified direction, while collecting representation information of the turnout and determining a position of the turnout.Type: GrantFiled: October 31, 2018Date of Patent: August 8, 2023Assignee: CASCO SIGNAL CO., LTD.Inventors: Ruiyuan Ye, Ting Jiang, Xinxin Li, Liang Chen, Weijuan Li, Zenghua Fang, Xiaonan Liu, Man Xu
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Patent number: 11651862Abstract: A system and method for predicting mild cognitive impairment (MCI) related diagnosis and prognosis utilizing deep learning. More specifically, the system and method produce predictions of MCI conversions to Alzheimer's/dementia and prognosis related thereof. Using available medical imaging and non-imaging data a diagnosis and prognosis model is a deep learned model trained using transfer learning. An MCI-DAP server may then receive a request from a clinician to process predictions related to a target patient's diagnosis or prognosis. The target patient's medical data is retrieved and used to create a model for the target patient. Then details of the target patient's model and the diagnosis and prognosis model are compared, a prediction is generated, and the prediction is returned to the clinician. As new medical data becomes available it is fed into the respective model to improve accuracy and update predictions.Type: GrantFiled: July 15, 2022Date of Patent: May 16, 2023Assignee: MS TECHNOLOGIESInventors: Yuan-Ming Fleming Lure, Jing Li, Teresa Wu, David Weidman, Kewei Chen, Xiaonan Liu, Yi Su
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Publication number: 20230042243Abstract: A system and method for predicting mild cognitive impairment (MCI) related diagnosis and prognosis utilizing hybrid machine learning. More specifically, the system and method produce predictions of MCI conversions to dementia and prognosis related thereof. Using available medical imaging and non-imaging data a diagnosis and prognosis model is trained using transfer learning. A platform may then receive a request from a clinician for a target patient's diagnosis or prognosis. The target patient's medical data is retrieved and used to create a model for the target patient. Then details of the target patient's model and the diagnosis and prognosis model are compared, a prediction is generated, and the prediction is returned to the clinician. As new medical data becomes available it is fed into the respective model to improve accuracy and update predictions.Type: ApplicationFiled: October 20, 2022Publication date: February 9, 2023Inventors: Yuan-Ming Fleming Lure, Jing Li, Teresa Wu, David Weidman, Kewei Chen, Xiaonan Liu, Yi Su
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Publication number: 20220367056Abstract: A system and method for predicting mild cognitive impairment (MCI) related diagnosis and prognosis utilizing deep learning. More specifically, the system and method produce predictions of MCI conversions to Alzheimer's/dementia and prognosis related thereof. Using available medical imaging and non-imaging data a diagnosis and prognosis model is a deep learned model trained using transfer learning. An MCI-DAP server may then receive a request from a clinician to process predictions related to a target patient's diagnosis or prognosis. The target patient's medical data is retrieved and used to create a model for the target patient. Then details of the target patient's model and the diagnosis and prognosis model are compared, a prediction is generated, and the prediction is returned to the clinician. As new medical data becomes available it is fed into the respective model to improve accuracy and update predictions.Type: ApplicationFiled: July 15, 2022Publication date: November 17, 2022Inventors: Yuan-Ming Fleming Lure, Jing Li, Teresa Wu, David Weidman, Kewei Chen, Xiaonan Liu, Yi Su
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Publication number: 20220344051Abstract: A system and method for predicting mild cognitive impairment (MCI) related diagnosis and prognosis utilizing deep learning. More specifically, the system and method produce predictions of MCI conversions to Alzheimer's/dementia and prognosis related thereof. Using available medical imaging and non-imaging data a diagnosis and prognosis model is a deep learned model trained using transfer learning. An MCI-DAP server may then receive a request from a clinician to process predictions related to a target patient's diagnosis or prognosis. The target patient's medical data is retrieved and used to create a model for the target patient. Then details of the target patient's model and the diagnosis and prognosis model are compared, a prediction is generated, and the prediction is returned to the clinician. As new medical data becomes available it is fed into the respective model to improve accuracy and update predictions.Type: ApplicationFiled: July 5, 2022Publication date: October 27, 2022Inventors: Yuan-Ming Fleming Lure, Jing Li, Teresa Wu, David Weidman, Kewei Chen, Xiaonan Liu, Yi Su
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Publication number: 20220262514Abstract: A system and method for predicting mild cognitive impairment (MCI) related diagnosis and prognosis. More specifically, the system and method produce predictions of MCI conversions to dementia and prognosis related thereof. Using available medical imaging and non-imaging data a diagnosis and prognosis model is trained using transfer learning. A server may then receive a request from a clinician for a target patient's diagnosis or prognosis. The target patient's medical data is retrieved and used to create a model for the target patient. Then details of the target patient's model and the diagnosis and prognosis model are compared, a prediction is generated, and the prediction is returned to the clinician. As new medical data becomes available it is fed into the respective model to improve accuracy and update predictions.Type: ApplicationFiled: December 22, 2021Publication date: August 18, 2022Inventors: Yuan-Ming Fleming Lure, Jing Li, Teresa Wu, David Weidman, Kewei Chen, Xiaonan Liu
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Publication number: 20220027681Abstract: A method and an apparatus are for classifying data. In an embodiment, the method includes: classifying at least two pieces of data, to obtain at least two data clusters; determining a bias degree of classification; re-classifying the at least two pieces of data by merging any several of the at least two data clusters; determining a bias degree of re-classification; and determining, by comparing the bias degree of first classification and the bias degree of re-classification, which classification is more accurate. By way of the method and apparatus, a related data cluster can be found from multiple data clusters for better data analysis.Type: ApplicationFiled: December 3, 2018Publication date: January 27, 2022Applicant: Siemens Mobility GmbHInventors: Congchao LI, Changwei LOH, Chaohua WU, Xiaonan LIU, Haotian HUI, Lei LU
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Publication number: 20210171075Abstract: The disclosure relates to a non-national standard turnout drive system based on a double 2-vote-2 architecture, including an interlocking processing subsystem IPS, an interlocking maintenance station SDM, a non-national standard turnout drive module HIOM and an interlocking maintenance station SDM, wherein the non-national standard turnout drive module HIOM, a full-electronic communication module EIOCOM2, and the interlocking processing subsystem IPS are connected with each other in order, and the full-electronic communication module EIOCOM2 is connected to the interlocking maintenance station SDM; two non-national standard turnout drive module HIOMs, which are mutually redundant, obtain turnout drive commands through the interlocking processing subsystem IPS to control drive relays in a non-national standard turnout to lift and fall for driving the turnout to rotate toward a specified direction, while collecting representation information of the turnout and determining a position of the turnout.Type: ApplicationFiled: October 31, 2018Publication date: June 10, 2021Inventors: Ruiyuan YE, Ting JIANG, Xinxin LI, Liang CHEN, Weijuan LI, Zenghua FANG, Xiaonan LIU, Man XU
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Patent number: 10944083Abstract: A method for manufacturing an array substrate, an array substrate and a display panel are provided herein. The method for manufacturing the array substrate includes: forming an inorganic layer on a base substrate; defining a preset region in a marginal region of the base substrate, and removing the inorganic layer in the preset region; and cutting the base substrate or the base substrate together with one or more layers on the base substrate in the preset region.Type: GrantFiled: October 16, 2018Date of Patent: March 9, 2021Assignees: BOE TECHNOLOGY GROUP CO., LTD., CHENGDU BOE OPTOELECTRONICS TECHNOLOGY CO., LTD.Inventors: Chong Lv, Fuqiang Tang, Xiaonan Liu, Yihong Zeng, Ruinan Song, Fujiang Jin
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Publication number: 20210039683Abstract: The present invention relates to a platform door control apparatus based on a double 2-vote-2 architecture, including a security communication and logic processing module, a driver collection module, and a maintenance module, the security communication and logic processing module is separately connected to the driver collection module and the maintenance module, and both the security communication and logic processing module and the driver collection module are devices using the double 2-vote-2 architecture. Compared with the prior art, the present invention has the following advantages of effectively improving linkage efficiency of a signal system and a platform door system, and the like.Type: ApplicationFiled: March 15, 2019Publication date: February 11, 2021Inventors: Ruiyuan YE, Xiaolin TANG, Liang CHEN, Zhijun JI, Chang LIU, Chun YANG, Xiaonan LIU, Jing XU
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Publication number: 20190288243Abstract: A method for manufacturing an array substrate, an array substrate and a display panel are provided herein. The method for manufacturing the array substrate includes: forming an inorganic layer on a base substrate; defining a preset region in a marginal region of the base substrate, and removing the inorganic layer in the preset region; and cutting the base substrate or the base substrate together with one or more layers on the base substrate in the preset region.Type: ApplicationFiled: October 16, 2018Publication date: September 19, 2019Inventors: Chong Lv, Fuqiang Tang, Xiaonan Liu, Yihong Zeng, Ruinan Song, Fujiang Jin
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Patent number: 10043220Abstract: A method, device and terminal for data processing are described. The method includes receiving a data exchange request, acquiring a responding user data queue corresponding to a requesting user according to a user correlation relationship, sorting and marking the responding user data queue with responding user information; converting the responding user data queue into a requesting user data queue, sorting and marking the requesting user data queue with requesting user information; and transmitting the requesting user data queue to a user terminal.Type: GrantFiled: July 10, 2015Date of Patent: August 7, 2018Assignee: Tencent Technology (Shenzhen) Company LimitedInventors: Xiaonan Liu, Huan Xiong
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Publication number: 20150319238Abstract: A method, device and terminal for data processing are described. The method includes receiving a data exchange request, acquiring a responding user data queue corresponding to a requesting user according to a user correlation relationship, sorting and marking the responding user data queue with responding user information; converting the responding user data queue into a requesting user data queue, sorting and marking the requesting user data queue with requesting user information; and transmitting the requesting user data queue to a user terminal.Type: ApplicationFiled: July 10, 2015Publication date: November 5, 2015Inventors: Xiaonan LIU, Huan XIONG
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Patent number: 6258751Abstract: The present invention relates to novel heterocyclic compounds and their agronomically suitable salts, methods for the use of these compounds in controlling unwanted plant species, and the use of herbicidal compositions containing these compounds. In particular, the present invention pertains to substituted and unsubstituted triazoles, imidazoles and pyrazoles linked to a heterocyclic substituted benzene group. Such compounds are useful as pre-emergent and post-emergent herbicides.Type: GrantFiled: June 13, 2000Date of Patent: July 10, 2001Assignee: Rohm and Haas CompanyInventors: Richard Martin Jacobson, Mark Joseph Mulvihill, Changling Liu, Xiaonan Liu