Patents by Inventor Xiao Xiao

Xiao Xiao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250037271
    Abstract: A method for three-dimensional reconstruction of a tumor-affected tissue is provided. The method includes the steps of: acquiring a plurality of slide images, each of which corresponds to a pathology section of the tumor-affected tissue; defining, on each of the slide images, at least one closed infiltration zone, the closed infiltration zone enclosing at least a portion of deep tissue in the pathology section; performing three-dimensional reconstruction by using the slide images having closed infiltration zones defined therein, thereby obtaining an infiltration space of the tumor-affected tissue; and determining three-dimensional occupancy of a tumor in the tumor-affected tissue, and defining a part of the tumor within the infiltration space as infiltrated, and defining another part of the tumor outside the infiltration space as non-infiltrated. A system and a computer readable medium for performing the three-dimensional reconstruction method are also provided.
    Type: Application
    Filed: October 6, 2023
    Publication date: January 30, 2025
    Inventors: XIAO XIAO, XIAOHAI XU, JINGJIA LIU
  • Patent number: 12209251
    Abstract: The present invention provides mutant adeno-associated virus serotype 5 (AAV5) that exhibit altered capsid properties, e. g., increased infectivity in human liver cells and/or minimal binding to human neutralizing antibodies. The present invention further provides libraries of mutant AAV5 comprising one or more mutations in a capsid gene. The present invention further provides methods of generating the mutant AAV5 and mutant AAV5 libraries, and compositions comprising the mutant AAV5. The present invention further provides recombinant AAV5 (rAAV5) virions that comprise a mutant capsid protein. The present invention further provides nucleic acids comprising nucleotide sequences that encode mutant capsid proteins.
    Type: Grant
    Filed: May 4, 2021
    Date of Patent: January 28, 2025
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Xiao Xiao, Randolph Qian, Juan Li
  • Patent number: 12209263
    Abstract: The invention relates to synthetic liver-specific promoters and expression constructs for producing polypeptides and functional nucleic acids in the liver of a subject. The invention further relates to optimized polynucleotide sequences encoding Factor IX proteins, vector comprising the same, and methods of using these compositions to treat a bleeding disorder.
    Type: Grant
    Filed: November 17, 2022
    Date of Patent: January 28, 2025
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Xiao Xiao, Juan Li
  • Patent number: 12200741
    Abstract: A data processing method includes receiving by an access network device a vehicle-to-everything (V2X) communication parameter of a group member device. The method also includes storing, by the access network device, the V2X communication parameter with context about a group to which the group member device belongs. The V2X communication parameter is used for allocation of a ProSe communication 5 (PC5) resource to the group member device.
    Type: Grant
    Filed: November 19, 2021
    Date of Patent: January 14, 2025
    Assignee: HUAWEI TECHNOLOGIES CO., LTD.
    Inventors: Jiangwei Ying, Meng Li, Xiao Xiao, Yanmei Yang
  • Patent number: 12197804
    Abstract: A method includes: in response to a dual-screen display instruction, entering a dual-screen display phase; in the dual-screen display phase, controlling a first display interface to be switched between a first display screen and a first display sub-screen in a time-division manner; and when the first display interface is switched to the first display screen, transmitting data of a first image to the first display screen through the first display interface, or when the first display interface is switched to the first display sub-screen, transmitting data of a second image to the first display sub-screen through the first display interface, so that the first display sub-screen displays the second image at the same time when the first display screen displays the first image.
    Type: Grant
    Filed: August 25, 2021
    Date of Patent: January 14, 2025
    Assignee: Huawei Technologies Co., Ltd.
    Inventors: Kai Hu, Xiao Xiao, Qiyi Li
  • Publication number: 20250016253
    Abstract: Provided are a data transmission method of a communication system, a terminal, and a network-side device. The method includes: receiving at a first protocol layer, by a sending-end device, a first data packet of a first plane from a second protocol layer; generating at the first protocol layer, by the sending-end device, a protocol data unit PDU of the first protocol layer based on the first data packet, where the PDU includes first indication information for indicating the second protocol layer; delivering at the first protocol layer, by the sending-end device, the PDU to a third protocol layer, where the third protocol layer is an immediately lower layer of the first protocol layer; and sending, by the sending-end device, the PDU through a first plane bearer for transmitting data of the first plane.
    Type: Application
    Filed: September 25, 2024
    Publication date: January 9, 2025
    Inventors: Hongping ZHANG, Xiao XIAO, Wei BAO
  • Patent number: 12192743
    Abstract: Embodiments of the present invention provide a V2X message sending method, apparatus, and system, and relate to the field of Internet of Vehicles. The method includes: obtaining, by a terminal, first configuration information, where the first configuration information is used for determining a first transmission resource pool; determining the first transmission resource pool based on the first configuration information; selecting a first transmission resource from the first transmission resource pool in a first transmission resource obtaining manner when a preset condition is met; and sending a V2X message by using the first transmission resource.
    Type: Grant
    Filed: August 11, 2023
    Date of Patent: January 7, 2025
    Assignee: HUAWEI TECHNOLOGIES CO., LTD.
    Inventors: Mingchao Li, Zhenzhen Cao, Xiao Xiao
  • Patent number: 12192773
    Abstract: A communication method and apparatus are disclosed. According to the communication method, corresponding PDCP entities of a first terminal and a second terminal use consistent input parameters when executing security algorithms, thereby ensuring normal communication on a sidelink (SL) and improving communication reliability. In an example embodiment, a first terminal determines a logical channel identifier (LCID) meeting a preset condition, where a first packet data convergence protocol (PDCP) entity of the first terminal is associated with two or more logical channels (LCHs); the first terminal receives a first data packet from a second terminal; and the first PDCP entity of the first terminal parses the first data packet based on the LCID.
    Type: Grant
    Filed: June 29, 2022
    Date of Patent: January 7, 2025
    Assignee: HUAWEI TECHNOLOGIES CO., LTD.
    Inventors: Xiangyu Li, Xiao Xiao, Bo Zhang, Jun Wang
  • Publication number: 20250004837
    Abstract: A method, computer program product, and computer system for dynamically allocating shared memory among multiple execution threads via use of a dynamically changing memory threshold. A trained machine learning model (MLM) is executed to calculate the memory threshold (MTH) using values of one or more input parameters as input to the MLM. After executing the MLM, a request is received from a requesting execution thread for a requested amount (MR) of the shared memory. In response to the request, the shared memory is distributed among one or more current execution threads currently using the shared memory and the requesting execution thread. The redistributing is performed as a function MTH, MR, MU, and MC, wherein MU is a total amount of the shared memory currently being used by the one or more current execution threads, and wherein MC is a memory capacity of the shared memory.
    Type: Application
    Filed: June 28, 2023
    Publication date: January 2, 2025
    Inventors: Ying Zhang, Sheng Yan Sun, Peng Hui Jiang, Xiao Xiao Chen
  • Publication number: 20240427808
    Abstract: Embodiments relate to using a large language model (LLM) to generate a list of items at an online system with a user defined constraint. The online system receives a query that includes at least one constraint. The online system generates a prompt for input into the LLM, based at least in part on the query. The online system requests the LLM to generate, based on the prompt, a set of constraints for a set of item types. The online system generates a list of candidate items by searching through a set of items stored in one or more non-transitory computer-readable media using the set of constraints for the set of item types. The online system causes a device of the user to display a user interface with the list of items for inclusion into a cart, the list of items obtained from the list of candidate items.
    Type: Application
    Filed: June 26, 2023
    Publication date: December 26, 2024
    Inventors: Vinesh Reddy Gudla, Sudha Rani Kolavali, Taesik Na, Xiao Xiao, Nkemakonam Paulet Okoye
  • Patent number: 12174779
    Abstract: An FPGA-based USB3.0/3.1 control system, including: a USB control module including a USB3.0 control module and/or a USB3.1 control module; a PCS logic module connected to the USB control module via a PIPE interface; an FPGA Serdes serial communication module connected to the PCS logic module; and an external daughter card module connected to the FPGA Serdes serial communication module, wherein the PCS logic module, the FPGA Serdes serial communication module and the external daughter card module are connected in sequence to achieve a port physical layer function for testing the USB 3.0 control module and the USB 3.1 control module. The control system solves the cumbersome problems of incomplete emulation verification, test mode limitations, and unchangeable hardware functions in the prior art.
    Type: Grant
    Filed: January 29, 2021
    Date of Patent: December 24, 2024
    Assignee: Corigine (Shanghai), Inc.
    Inventors: Zhihao Yin, Sheng Lu, Kai Fan, Xiao Xiao, Kai Cheng
  • Publication number: 20240398756
    Abstract: Disclosed is a drug for lowing blood glucose and/or improving diabetic complications, belonging to the technical field of biomedicine. According to the present disclosure, the drug for lowing blood glucose and/or improving diabetic complications is nanoparticles formed by a component containing lipoic acid and/or lipoic acid derivatives. The lipoic acid nanoparticles not only can control blood glucose safely and long-term, but also can realize the prevention/treatment of diabetic complications through lowering blood glucose and inhibiting oxidative stress. This drug has good clinical prospect.
    Type: Application
    Filed: August 14, 2024
    Publication date: December 5, 2024
    Inventors: Shiyong Zhang, Xiao Xiao, Xiaoluan Lu, Yuhong Zhu, Yulong Liao, Chunyan Liao, Xiao Wu
  • Patent number: 12156804
    Abstract: An optical device including a partial or incomplete optic configured operatively as an add-on (e.g., supplemental lens/optic) for an (existing) optical element or system, the partial or incomplete optic having an active area configured in relation to the optical element or system such that the partial or incomplete optic controls or changes foci of light incident upon or provided to the active area, but does not control or change foci of light bypassing optically relevant portions of the partial or incomplete optic, and associated methods for enhancing vision.
    Type: Grant
    Filed: July 27, 2021
    Date of Patent: December 3, 2024
    Assignee: Hoya Corporation
    Inventor: Xiao Xiao Zhang
  • Patent number: 12160536
    Abstract: A method includes: when it is determined that a user's gesture of moving an electronic device is a preset gesture, obtaining a capacitance measurement value sensed at a contact in a preset area of the touchscreen, where the preset area is located in a peripheral edge area of the touchscreen; and when the obtained capacitance measurement value meets a first preset condition, controlling display status switching of the touchscreen.
    Type: Grant
    Filed: July 20, 2020
    Date of Patent: December 3, 2024
    Assignee: Honor Device Co., Ltd.
    Inventors: Junfeng Yu, Xiao Xiao, Weigang Cai, Hongda Chen, Jianli Shao
  • Publication number: 20240372323
    Abstract: The disclosure provides a single-mode external-cavity diode laser based on an s-AFPF, relates to the technical field of tunable diode laser absorption spectroscopy. A piezoelectric ceramic actuator is used to change and modulate an output center wavelength of the laser, so that the center wavelength of laser light can periodically scan an absorption spectrum band of a gas to be detected. To better apply tunable diode laser absorption spectroscopy-wavelength modulation spectroscopy to the apparatus of the disclosure, a curved groove structure is further proposed, and this structure can limit a ping-pong effect of a steel ball when vibration of KHz level from the tunable diode laser absorption spectroscopy-wavelength modulation spectroscopy appears on the piezoelectric ceramic actuator. The tunable external-cavity diode laser based on a narrow-band interference filter designed by the disclosure accurately senses the types and concentrations of various gases.
    Type: Application
    Filed: August 23, 2023
    Publication date: November 7, 2024
    Inventors: Xiao Xiao, Jianquan Zhang, Guopeng Zhou, Zhibin Wang
  • Publication number: 20240365263
    Abstract: Embodiments of the present disclosure provide a data transmission method and apparatus. The method includes: receiving, by user equipment UE, first synchronization source configuration information on a first carrier; determining, a first synchronization source based on the first synchronization source configuration information; determining that synchronization with the first synchronization source fails; determining a second synchronization source and a transmission resource; and transmitting data on a second carrier using the determined transmission resource and based on the second synchronization source, where the first synchronization source is used to provide the UE with a synchronization clock required for transmitting the data on the second carrier, and a frequency of the first carrier is different from a frequency of the second carrier.
    Type: Application
    Filed: July 8, 2024
    Publication date: October 31, 2024
    Inventors: Mingchao LI, Zhenzhen CAO, Xiao XIAO, Guanglin HAN
  • Patent number: 12120725
    Abstract: A communications system, method and apparatus, the apparatus configured for determining configuration information of a default data radio bearer (DRB) of a first link, the first link being a direct wireless communications link between a first terminal device and another terminal device, and the first terminal device being a transmit end of a first vehicle-to-everything (V2X) data packet, and sending the configuration information of the default DRB of the first link to the first terminal device, where the configuration information of the default DRB of the first link has first indication information, and the first indication information indicating that the configuration information is the configuration information of the default DRB of the first link.
    Type: Grant
    Filed: September 27, 2021
    Date of Patent: October 15, 2024
    Assignee: HUAWEI TECHNOLOGIES CO., LTD.
    Inventors: Xiangyu Li, Xiao Xiao, Wenjie Peng, Jun Wang, Mingzeng Dai
  • Patent number: 12116398
    Abstract: The invention relates to synthetic liver-specific promoters and expression constructs for producing polypeptides and functional nucleic acids in the liver of a subject. The invention further relates to Factor VIII proteins containing modifications in the amino acid sequence of the Factor VIII protein, as well as nucleic acid constructs encoding the Factor VIII proteins and methods of using these compositions to treat a bleeding disorder.
    Type: Grant
    Filed: May 20, 2019
    Date of Patent: October 15, 2024
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Xiao Xiao, Juan Li, Zhenhua Yuan
  • Publication number: 20240327502
    Abstract: The present invention relates to anti-human metapneumovirus (hMPV) antibodies, as well as use of such antibodies in the treatment of viral infections. The invention also includes antigenic hMPV proteins and immunogenic compositions comprising such antigenic hMPV proteins, and the use of such antigenic hMPV proteins and related compositions for preventing or treating viral infection in a subject.
    Type: Application
    Filed: February 8, 2022
    Publication date: October 3, 2024
    Applicant: MERCK SHARP & DOHME LLC
    Inventors: Zhifeng CHEN, Kara S. COX, Arthur FRIDMAN, Jennifer Dawn GALLI, Hua-Poo SU, Aimin TANG, Kalpit VORA, Zhiyun WEN, Xiao XIAO, Lan ZHANG
  • Publication number: 20240327980
    Abstract: The present application provides a method for a manufacturing semiconductor structure and a semiconductor growth device.
    Type: Application
    Filed: July 20, 2022
    Publication date: October 3, 2024
    Inventors: Yang CHENG, Jun WANG, Xiao XIAO, Yintao GUO