Abstract: A PTMC-based intestinal anastomosis stent of a bioabsorbable flexible elastomer and a preparation method therefor. The intestinal anastomosis stent that uses PTMC as a base material is prepared by using an electrospinning method, and an appropriate range suitable for being implanted into the body is screened out according to a degradation rate and a mechanical property. The stent is loaded with TCS having a bactericidal effect, so that the stent has a tissue repair adjustment function, enabling a wound to heal more quickly in a severe multi-bacterial intestinal environment, and for adjusting postoperative tissue healing and functional repair. An in-vivo animal intestinal anastomosis experiment is carried out, thus verifying the practical effects and the feasibility of the method.

Abstract: The present disclosure provides one or more engineered nucleases and systems, compositions, and methods thereof, wherein the one or more engineered nucleases can be used to effect binding, cleaving, and/or editing a target polynucleotide sequence. The one or more engineered nucleases can be engineered variants of a small CRISPR/Cas protein.

Abstract: A method for deep learning. The method includes: receiving, by a deep learning model, a plurality of samples and a plurality of labels corresponding to the plurality of samples; adversarially augmenting, by the deep learning model, the plurality of samples based on a threat model; and assigning, by the deep learning model, a low predictive confidence to one or more adversarially augmented samples of the plurality of adversarially augmented samples having noisy labels due to the adversarially augmenting based on the threat model.

Abstract: Provided are a pixel driving circuit, a display panel, and a display device. Both a constant voltage signal line and a variable voltage signal line extend along a first direction. The constant voltage signal line includes an initialization voltage line, and the variable voltage signal line includes an initialization control signal line. A first electrode of an initialization transistor is electrically connected to the initialization voltage line, a second electrode of the initialization transistor is electrically connected to a first electrode or a second electrode of a drive transistor, and a gate of the initialization transistor is electrically connected to the initialization control signal line and used for turning on the initialization transistor according to a control signal on the initialization control signal line so as to initialize the first electrode or the second electrode of the drive transistor.

Abstract: A flexible intestinal anastomosis stent which sucks secretions on an inner wall of an intestinal tract and at a suture site into a horn-shaped channel through a through-hole. The secretion is discharged to an inside of the stent body through a liquid-inlet hole after being squeezed by intestinal tract contents, thereby reducing a risk of infection at the suture site. A lower edge of the outlet end of the stent body has a concave polygonal structure, each reflex angle at a lower edge of the concave polygonal structure being formed with one inwardly folded wrinkle structure on a side wall of the stent body, and the wrinkle structure also able to accommodate the secretions. The lower edge is stressed and deformed by the intestinal tract contents to reduce a reflex angle, so that secretions in the wrinkle structure are discharged downwardly, such that risk of complications is reduced.

Abstract: A backlight module, a display module, and a display device are provided. The backlight module includes a light-emitting area including a first light-emitting area and a second light-emitting area. The second light-emitting area at least partially surrounds the first light-emitting area. The backlight module also includes a light-emitting structure including a plurality of light-emitting elements distributed in the light-emitting area, and a diffusion plate located on a side of a light exiting surface of the light-emitting structure and at least partially located in the light-emitting area. The backlight module also includes a reflection structure located on a surface of the diffusion plate facing the light-emitting structure. The reflection structure overlaps with the first light-emitting area.

Abstract: An example computer-implemented method includes receiving agricultural data records comprising a first set of yield properties for a first set of seeds grown in a first set of environments, and receiving genetic feature data related to a second set of seeds. The method further includes generating a second set of yield properties for the second set of seeds associated with a second set of environments by applying a model using the genetic feature data and the agricultural data records. In addition, the method includes determining predicted yield performance for a third set of seeds associated with one or more target environments by applying the second set of yield properties, and generating seed recommendations for the one or more target environments based on the predicted yield performance for the third set of seeds. In the present example, the method also includes causing display of the seed recommendations.

Abstract: Disclosed herein is a method for the treatment or delay of progression of cancer in a subject, comprising administering to the subject in need thereof a BTK inhibitor, for example, (S)-7-(1-acryloylpiperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetra-hydropyrazolo[1,5-a]pyrimidine-3-carboxamide or a pharmaceutically acceptable salt thereof, in combination with a PI3K? inhibitor or a pharmaceutically acceptable salt thereof.

Abstract: The disclosure provides systems, compositions, methods for regulating aberrant expression of a target gene in cell (e.g., a muscle cell), to treat or ameliorate a disease or a condition in a subject (e.g., muscular dystrophy, such as Facioscapulohumeral Muscular Dystrophy (FSHD)).

Abstract: A screen sound production component is disposed on a back side of a screen. Based on a user having a high requirement for a sound receiving effect, a high requirement for confidentiality of sound content, or a high requirement for sound quality, the mobile terminal depends on the screen sound production component to drive the screen to vibrate, so as to produce sound, that is, the mobile terminal uses a privacy mode. In the privacy mode, a location at which the screen produces sound is close to the ear of the user. Therefore, it can be ensured that the user directly receives a large amount of sound produced by the screen, instead of mainly receiving sound by using a sound output hole on the mobile terminal.

Abstract: Aspects of the invention relate to methods for preparing and analyzing a sequencing library from a mixed cell-free DNA (cfDNA) sample, wherein the mixed sample includes double-stranded DNA (dsDNA), damaged dsDNA (e.g., nicked dsDNA), and single-stranded DNA (ssDNA) molecules. The subject methods facilitate the collection of information from dsDNA, ssDNA and damaged DNA (e.g., nicked DNA) molecules in a sample, thereby providing enhanced diagnostic information as compared to sequencing libraries that are prepared from dsDNA alone.

Abstract: Embodiments generate digital plans for agricultural fields. In an embodiment, a model receives digital inputs including stress risk data, product maturity data, field location data, planting date data, and/or harvest date data. The model mathematically correlates sets of digital inputs with threshold data associated with the stress risk data. The model is used to generate stress risk prediction data for a set of product maturity and field location combinations. In a digital plan, product maturity data or planting date data or harvest date data or field location data can be adjusted based on the stress risk prediction data. A digital plan can be transmitted to a field manager computing device. An agricultural apparatus can be moved in response to a digital plan.

Abstract: Embodiments of the present invention provide a sound recording method and apparatus. The method includes: displaying, by a terminal device, a first interface, where the first interface includes a first control, and the first control includes: a first option used for selecting a recording whose output specification is sound quality with a first bit width, and a second option used for selecting a recording whose output specification is sound quality of a second bit width; and processing, by the terminal device in a case that the terminal device receives an operation of selecting the first option, a recording obtained by a microphone, to obtain a recording with the first bit width; or processing, by the terminal device in a case that the terminal device receives an operation of selecting the second option, a recording obtained by a microphone, to obtain a recording with the second bit width.

Abstract: A method of index searching of consent-protected private healthcare data includes receiving, from a computing device, a search request for access to consent-protected healthcare data stored at a consent-indexed healthcare data store. The request includes one or more consent parameters asserted for a user of the computing device. The method also includes identifying one or more asserted access consent scenarios for accessing the requested consent-protected healthcare data based on the one or more consent parameters, each asserted access consent scenario of the one or more asserted access consent scenarios representing a respective subset of the one or more consent parameters. The method further includes defining a search filter based on the one or more asserted access consent scenarios and determining, via an indexed search of the data store using the search filter, a subset of the requested data. The method includes providing the subset of data to the computing device.

Abstract: The present application relates to a rope fixation device, a rope transmission device, and an ultrasound probe. The rope fixation device includes a drive shaft, a rope, and a fixing member. The drive shaft is provided with a rope through-hole and a fixing hole. The fixing hole is in communication with the rope through-hole. The rope through-hole penetrates through the drive shaft. Two opposite ends of the rope through-hole are both located on the side wall of the drive shaft. The rope extends through the rope through-hole, and two ends of the rope respectively protrude out from the two opposite ends of the rope through-hole. The fixing member is inserted into the fixing hole. One end of the fixing member adjacent to the rope through-hole includes an end surface. At least part of the end surface abuts against the rope, thereby fixing the rope in the rope through-hole.

Abstract: This application discloses a data fusion method and a related device. The method includes: obtaining vehicle sensing data, where the vehicle sensing data is obtained by a vehicle sensing apparatus by sensing a road environment in a sensing range by using a vehicle sensor; obtaining roadside sensing data, where the roadside sensing data is obtained by a roadside sensing apparatus by sensing a road environment in a sensing range by using a roadside sensor; and fusing the vehicle sensing data and the roadside sensing data by using a fusion formula, to obtain a first fusion result. According to the foregoing solution, overlapping can be implemented between the sensing range of the roadside sensing apparatus and the sensing range of the vehicle sensing apparatus can be implemented, so that the sensing range is effectively extended.

Abstract: Systems and methods are provided that include a processor executing a program to match sentences from a sentence dataset with artistic phrases from an artistic phrase dataset to generate a plurality of safe phrases. The processor is further configured to, for each of the safe phrases, generate a safe image by, for a predetermined number of iterations, performing steps to input an initial image into a diffusion process to generate a processed image, wherein the diffusion process includes a first diffusion model, back-propagate the processed image through a text-image match gradient calculator to calculate a gradient against the safe phrase, and update the initial image by applying the gradient to the processed image. The processor is further configured to pair each of the generated safe images with their respective safe phrase to form a plurality of safe phrase-image pairs.

Abstract: Systems and methods are provided that include a processor executing a program to receive input text from a user. The processor is further configured to, for a predetermined number of iterations, input an initial image into a diffusion process to generate a processed image, back-propagate the processed image through a text-image match gradient calculator to calculate a gradient against the input text, and update the initial image with an image generated by applying the calculated gradient to the processed image. The pixel values of the processed image during a first portion of the predetermined number of iterations are value clamped to a first range, and pixel values of the processed image during a second portion of the predetermined number of iterations are value clamped to a second range that is a subset of the first range.

Abstract: Systems and methods are provided that include a processor executing a program to receive an input from a user, where the input including a first input text and a second input text. The processor is further configured to provide an initial image and, for a predetermined number of iterations, define a first and second regions of the initial image associated with the first and second input texts, respectively, define a plurality of patches of the initial image, input the initial image into a diffusion process to generate a processed image, back-propagate the processed image through a text-image match gradient calculator by generating an image embedding based on the processed image, generating a text embedding based on the region and the input text that are associated with a patch, and calculating a differential between the image embedding and the text embedding.

Abstract: Systems and methods are provided that include a processor executing a program to process an initial image through a first diffusion stage to generate a final first stage image, wherein the first diffusion stage includes using a diffusion model, a gradient estimator model smaller than the diffusion model, and a text-image match gradient calculator. The processor further executes the program to process the final first stage image through a second diffusion stage to generate a final second stage image. The second diffusion stage includes, for a second predetermined number of iterations, inputting the final first stage image to through the diffusion model, back-propagate the image through the text-image match gradient calculator to calculate a second stage gradient against the input text, and update the final first stage image by applying the second stage gradient to the final first stage image.