Abstract: Techniques are provided for generating target success group of hybrid seeds for target fields include a server receiving agricultural data records that represent crop seed data describing seed and yield properties of hybrid seeds and first field geo-location data for agricultural fields where the hybrid seeds were planted. The server receives second geo-locations data for target fields where hybrid seeds are to be planted. The server generates a dataset of hybrid seed properties that include yield values and environmental classifications for hybrid seeds and then a dataset of success probability scores that describe the probability of a successful yield on the target fields based on the dataset of hybrid seed properties and the second geo-location data. The server generates target success yield group of hybrid seeds and probability of success values based on success probability scores and a yield threshold. The server causes display of the target success yield group.

Abstract: Techniques are provided for generating a set of target hybrid seeds with optimal yield and risk performance, including a server receiving a candidate set of hybrid seeds along with probability of successful yield values, associated historical agricultural data and property information, and selecting a subset of the hybrid seeds that have probability of success values greater than a filtering threshold. The server generates representative yield values for hybrid seeds based on the historical agricultural data and risk values for each hybrid seed. The server generates a dataset of target hybrid seeds for planting based on the risk values, the yield values, and the properties for the target fields. The dataset of target hybrid seeds includes target hybrid seeds that meet a specific threshold for a range of risk values. The server causes display of the dataset of target hybrid seeds including yield values and risk values for the target fields.

Abstract: The present disclosure provides the use of a recombinant human secretory DDRGK1. Experiments demonstrate that the recombinant human secretory DDRGK1 prepared by the present disclosure can be used in the preparation of biological medicines for treating intervertebral disc degeneration, fractures or bone defects. The recombinant human secretory DDRGK1 of the present disclosure provides a promising direction for the treatment of bone related diseases and has obtained firm scientific evidence, thereby expanding the further application of recombinant human secretory DDRGK1 in clinical practice.

Abstract: The present invention relates to a disposable dental appliance and, more particularly, a dental prophy angle used for cleaning and polishing teeth, especially, a prophy angle for holding a disposable polishing/cleaning cup-head/brush-head that is disposed after each application to a patient to prevent potential cross contamination. The disposable prophy angle for a handpiece preferably comprises an elongated tubular housing, a drive shaft, a driven gear rotor, and a prophy cup/brush-head. The tubular housing has a longitudinal and a transverse section in one integral piece with a proximal end adapted to couple to a standard dental handpiece. The housing further has an extrusion-molded socket on its top inner surface. The housing has a horseshoe-like locker to position the drive shaft gear against the driven rotor gear. The driven rotor comprises a rotor head, a rotor neck, a driven rotor gear, a cup flange, a cup neck, and a cup holder.

Abstract: A device for imaging one dimension nanomaterials is provided. The device includes an optical microscope with a liquid immersion objective, a laser device, and a spectrometer. The laser device is configured to provide an incident light beam with a continuous spectrum. The spectrometer is configured to obtain spectral information of the one dimensional nanomaterials.

Abstract: Cell free nucleic acids from a test sample obtained from an individual are analyzed to identify possible fusion events. Cell free nucleic acids are sequenced and processed to generate fragments. Fragments are decomposed into kmers and the kmers are either analyzed de novo or compared to targeted nucleic acid sequences that are known to be associated with fusion gene pairs of interest. Thus, kmers that may have originated from a fusion event can be identified. These kmers are consolidated to generate gene ranges from various genes that match sequences in the fragment. A candidate fusion event can be called given the spanning of one or more gene ranges across the fragment.

Abstract: A method for recommending a drilling target of a new well based on cognitive computing is provided, including: establishing a reservoir geological model; acquiring a dynamic parameter and a static parameter; establishing multiple fuzzy rules bases; inputting the dynamic and static parameters into the fuzzy rules base to obtain aggregated output fuzzy sets of membership values; defuzzifying the fuzzy set of the membership values to obtain crisp values of the fuzzy variables; inputting the crisp values into the fuzzy rules base to obtain a aggregated output fuzzy set of DA membership values of drilling attractiveness DA as a fuzzy variable; defuzzifying the DA to obtain a score of the DA; establishing a drilling attractiveness region with a radius R by taking each grid as a center; calculating region drilling attractiveness RDA score of the region; and determining a region with a highest score as the location of the new well.

Abstract: The present disclosure provides methods and systems for identifying natural product-encoding multi-gene clusters (MGCs). In some embodiments, the present disclosure also teaches methods for producing sequenced and assembled metagenomic libraries that are amenable to MGC search bioinformatic tools and techniques.

Abstract: This invention relates to compounds of formula 1, 2 or 3 a pharmaceutically acceptable salt, or solvate thereof, wherein X1, Y, R1, R2, R3, R4, and R5 are as defined herein. The compounds are antimicrobial agents that may be used to treat various bacterial and protozoal infections and disorders related to such infections. The invention also relates to pharmaceutical compositions containing the compounds and to methods of treating bacterial and protozoal infections by administering the compounds of formula 1, 2 or 3.

Abstract: Cell free nucleic acids from a test sample obtained from an individual are analyzed to identify possible fusion events. Cell free nucleic acids are sequenced and processed to generate fragments. Fragments are decomposed into kmers and the kmers are either analyzed de novo or compared to targeted nucleic acid sequences that are known to be associated with fusion gene pairs of interest. Thus, kmers that may have originated from a fusion event can be identified. These kmers are consolidated to generate gene ranges from various genes that match sequences in the fragment. A candidate fusion event can be called given the spanning of one or more gene ranges across the fragment.

Abstract: A post insulator includes an insulating post including a first end and a second end that are opposite to each other, a high-voltage-end grading ring connected to the first end of the insulating post, the high-voltage-end grading ring being insulated from the insulating post, a grounding-end grading ring connected to the second end of the insulating post, the grounding-end grading ring being insulated from the insulating post, and a charge control ring disposed on an outer surface of the insulating post, the charge control ring being insulated from the insulating post, and the charge control ring being configured to accumulate surface charges.

Abstract: Provided herein are oseltamivir analogs useful for the treatment and prevention of viral infections, pharmaceutical compositions comprising the same and methods preparation and use thereof.

Abstract: Conventional email filtering services are not suitable for recognizing sophisticated malicious emails, and therefore may allow sophisticated malicious emails to reach inboxes by mistake. Introduced here are threat detection platforms designed to take an integrative approach to detecting security threats. For example, after receiving input indicative of an approval from an individual to access past email received by employees of an enterprise, a threat detection platform can download past emails to build a machine learning (ML) model that understands the norms of communication with internal contacts (e.g., other employees) and/or external contacts (e.g., vendors). By applying the ML model to incoming email, the threat detection platform can identify security threats in real time in a targeted manner.

Abstract: A comprehensive evaluation method of military training level includes: selecting evaluation indicators of military training level, and establishing an evaluation indicator system of military training level by a multi-tree structure; constructing a leaf node evaluation indicator fusion model including a time indicator fusion model and a quality indicator fusion model, and performing multi-source data fusion processing on leaf node indicator data through the leaf node evaluation indicator fusion model; constructing a leaf node evaluation indicator model of military training level; constructing a parent node evaluation indicator model of military training level based on weight information of evaluation indicators of military training level of nodes in the multi-tree structure; and constructing a total indicator evaluation model by a method of breadth first search of multi-tree to complete the comprehensive evaluation of military training level.

Abstract: A speaker includes a front cover, a coil, a frame, a magnet, a magnetic diaphragm, and a voice coil. The coil is located on an inner side of the front cover, the magnetic diaphragm is located between the coil and the voice coil, a periphery of the magnetic diaphragm is adhered to one side of the frame, the magnet is located on the other side of the frame, and the one side and the other side of the frame are two opposite sides of the frame. The voice coil is configured to drive the magnetic diaphragm to vibrate.

Abstract: A method can include receiving a first image depicting a first dog and identifying, with a first model, a first breed for the first dog based on the first image. The method may further include determining, with a second model, a first body condition for the first dog based on the first image; generating, with a third model, a second image depicting the first dog with a second body condition different from the first body condition. The method may also include labeling the first image with indications of the breed and the first body condition, labeling the second image with indications of the breed and the second body condition, and training the second model using the first and second images.

Abstract: Conventional email filtering services are not suitable for recognizing sophisticated malicious emails, and therefore may allow sophisticated malicious emails to reach inboxes by mistake. Introduced here are threat detection platforms designed to take an integrative approach to detecting security threats. For example, after receiving input indicative of an approval from an individual to access past email received by employees of an enterprise, a threat detection platform can download past emails to build a machine learning (ML) model that understands the norms of communication with internal contacts (e.g., other employees) and/or external contacts (e.g., vendors). By applying the ML model to incoming email, the threat detection platform can identify security threats in real time in a targeted manner.

Abstract: The disclosure relates to a photocatalytic structure. The photocatalytic structure includes a substrate, a photocatalytic active layer, and a metal layer. The substrate, the photocatalytic active layer, and the metal layer are arranged in succession. The substrate includes a base and a patterned bulge layer on a surface of the base. The patterned bulge layer is a net-like structure comprising a plurality of strip-shaped bulges intersected with each other and a plurality of indents defined by the plurality of strip-shaped bulges. The plurality of strip-shaped bulges is an integrated structure. The photocatalytic active layer is on the surface of the patterned bulge layer. The metal layer includes a plurality of nanoparticles located on the surface of the photocatalytic active layer away from the substrate.

Abstract: Provided are a backlight module, a preparation method thereof, and a display device. The backlight module includes a substrate, multiple light-emitting elements, a reflection structure and a rubber frame structure, and the multiple light-emitting elements, the reflection structure and the rubber frame structure are located on one side of the substrate. The multiple light-emitting elements and the reflection structure are located within a limited area of the rubber frame structure, and the reflection structure is located between every two adjacent light-emitting elements; and the reflection structure includes a first reflection surface adjacent to a light-emitting element, and the rubber frame structure includes a second reflection surface adjacent to the light-emitting element.

Abstract: Embodiments of the present invention provide a model parameter fusion method and apparatus, which relate to the field of machine learning and intend to reduce a data transmission amount and implement dynamical adjustment of computing resources during model parameter fusion. The method includes: dividing, by an ith node, a model parameter of the ith node into N blocks, where the ith node is any node of N nodes that participate in a fusion, and 1?i?N?M; receiving, by the ith node, ith model parameter blocks respectively sent by other nodes of the N nodes than the ith node; fusing, by the ith node, an ith model parameter block of the ith node and the ith model parameter blocks respectively sent by the other nodes, so as to obtain the ith general model parameter block; and distributing, by the ith node, the ith general model parameter block to the other nodes of the N nodes.