Abstract: An adhesive material that provides fast and robust adhesion on wet surfaces, where the adhesion formed is detachable on-demand. The adhesive material is formed of one or more hydrophilic polymers or copolymers grafted with one or more amine coupling groups via a plurality of cleavable physical bonds and/or cleavable covalent bonds and one or more cross linkers. Application of the adhesive material on a wet surface causes the adhesive material to absorb liquid to thereby swell the adhesive material to form a layer of hydrogel, resulting in the formation of temporary crosslinks followed by covalent crosslinks with the surface. Introducing a triggering agent cleaves the cleavable physical bonds and/or cleavable covalent bonds to allow for non-traumatic detachment of the adhesive material from the surface.

Abstract: The present invention belongs to the field of medicinal chemistry, and particularly relates to synthesis, a preparation method and the use of an inhibitor containing dual targets SHP2 and CDK4/6, wherein the inhibitor comprises three compounds of general formulas I-III and pharmaceutically acceptable salts, enantiomers, diastereomers, tautomers, solvates, polymorphs or prodrugs thereof. According to the present invention, a class of brand-new SHP2 and CDK4/6 dual-target inhibitors are prepared by means of a pharmacophore fusion and reasonable drug design method, so that the problems of drug resistance, poor drug effect, etc., of the existing SHP2 inhibitor and CDK4/6 inhibitor are solved; the great significance of the present invention is providing the first SHP2 and CDK4/6 dual-target inhibitor, which provides a basis for solving the problem of drug resistance of kinase and phosphatase in the later period.

Abstract: The invention relates to a polymer having a main chain which is obtained by free radical emulsion polymerisation of a monomer mixture, which comprises at least one optionally substituted styrene, at least one C1-C4 alkyl (meth)acrylate and at least one ethylenically unsaturated monomer. The monomer mixture is polymerised in a reaction mixture comprising a natural and/or synthetic polymeric stabilizer. According to the invention the polymer main chain further comprises a reaction product of silica sol and an unsaturated organosilicon compound. The invention relates also to methods of making such polymer.

Abstract: Disclosed are various embodiments for a visual language processing modeling framework via an attention-on-attention mechanism, which may be employed for object identification, classification, and the like. In association with a display of a user interface, an eye tracking via images captured by an imaging device is performed to programmatically detect eye movement and fixation relative to sub-regions of the user interface. Eye fixations on at least one of the sub-regions from the eye tracking. Visual cues are extracted from the user interface based at least in part on the eye fixations, the visual cues being in a sequence of identification. A visual language sentence is generated based at least in part on the visual cues as extracted. The visual language sentence of the visual cues in the sequence of identification is correlated to at least one decision using a visual language understanding routine.

Abstract: A method for model production includes acquiring a related operation for model production from a user interface layer of a model production system, and determining a software platform of the model production system; acquiring a model service corresponding to the related operation by invoking an application programming interface (API) corresponding to the related operation, wherein the API is located between the user interface layer and other layer in the model production system; performing the model service by invoking local resources of the software platform with a tool of the software platform adapted to the model service, to generate a target model; and applying the target model in a target usage scene.

Abstract: A remote data access method is applied to a first device that is coupled to and communicates with a second device. The first device and the second device each are configured with a network interface card (NIC) having a remote direct memory access (RDMA) function. The method is performed by a NIC of the first device, and the method includes: generating a first packet including a type identifier and a function identifier; and sending the first packet to the second device. The type identifier in the first packet indicates that the first packet is a remote memory function call (RMFC)-type packet, and the RMFC-type packet indicates the second device to perform a preset operation on local data of the second device. The function identifier in the first packet indicates an operation type of the preset operation.

Abstract: A service processing method and apparatus are provided, and relate to the field of computer technologies. The method includes: First, a first-type processor included in a server obtains a first message for requesting a first service. Second, the first-type processor parses the first message, and writes data needed by the first service into DMA space, where the DMA space is storage space provided by a memory of the server based on a DMA technology. Finally, a second-type processor whose performance is better than that of the first-type processor in the server reads the foregoing data from the DMA space, and outputs a processing result of the first service.

Abstract: A model updating method and apparatus, a storage medium, a terminal, and a network device are provided. The method includes: determining whether an update for a locally deployed model is required; and cooperating with a network to update the locally deployed model based on determining that the update for the locally deployed model is required.

Abstract: A method for obtaining data is provided. The method for obtaining data includes the following. A terminal device receives first configuration information from a network device, where the first configuration information indicates a data collection manner for a first model, a data preprocessing manner for the first model, and/or a data reporting manner for the first model, and the first model is an artificial intelligence (AI) model used by the network device. The terminal device performs corresponding configuration based on the first configuration information.

Abstract: A computing device includes a scheduling apparatus and at least two processing unit sets, each processing unit set includes at least one processing unit, and the scheduling apparatus is communicatively connected to processing units in the at least two processing unit sets. The data processing method in this application includes: The scheduling apparatus receives a data processing request, where the data processing request includes a function identifier, and the function identifier indicates a function that needs to be called to process the data processing request; and further, the scheduling apparatus determines a first processing unit set from the at least two processing unit sets of the computing device based on the function identifier, and determines a target processing unit in the first processing unit set, and the determined target processing unit processes the data processing request, to obtain a data processing result.

Abstract: An adhesive material that provides fast and robust adhesion on wet surfaces, where the adhesion formed is detachable on-demand. The adhesive material is formed of one or more hydrophilic polymers or copolymers grafted with one or more amine coupling groups via a plurality of cleavable physical bonds and/or cleavable covalent bonds and one or more cross linkers. Application of the adhesive material on a wet surface causes the adhesive material to absorb liquid to thereby swell the adhesive material to form a layer of hydrogel, resulting in the formation of temporary crosslinks followed by covalent crosslinks with the surface. Introducing a triggering agent cleaves the cleavable physical bonds and/or cleavable covalent bonds to allow for non-traumatic detachment of the adhesive material from the surface.

Abstract: A network interface card splits obtained data and an obtained address, generates a plurality of pairs of data and addresses, assembles the plurality of pairs of data and addresses to generate a plurality of write requests, places the plurality of write requests into a plurality of send queues (QPs), and then sends the write requests to a plurality of storage nodes for storage via a network.

Abstract: The present disclosure provides methods of treating an individual having Timothy syndrome. Aspects of the methods include administering an effective dose of an agent to the individual, wherein the agent modulates the splicing of an 8 A or an 8 exon of CACNA1C. Also provided are compositions that find use in practicing embodiments of the methods.

Abstract: Adapting user interface designs for specific tasks performed by different users is a challenging yet important problem. Automatically adapting visualization designs to users and contexts (e.g., tasks, display devices, environments, etc.) can theoretically improve human-computer interaction to acquire insights from complex datasets. However, effectiveness of any specific visualization is moderated by individual differences in knowledge, skills, and abilities for different contexts. A modeling framework called Personalized Recommender System for Information visualization Methods via Extended matrix completion (PRIME) is described for recommending the optimal visualization designs for individual users in different contexts.

Abstract: Computation pipeline-dataset exploration, visualization, and recommendation concepts are described. For example, a method can include learning first visualization latent-space features of different datasets represented in a first two-dimensional latent space and second visualization latent-space features of different computation pipelines represented in a second two-dimensional latent space. The method can also include modeling dataset-pipeline interactions between the different datasets and the different computation pipelines based on the first visualization latent-space features and the second visualization latent-space features. The method can also include learning relationships between the first visualization latent-space features and the second visualization latent-space features based on modeling the dataset-pipeline interactions. In another example, the method can further include generating a visual representation of the relationships and the dataset-pipeline interactions.

Abstract: Disclosed are a method and device for processing overheat and a storage medium. The method for processing overheat includes: obtaining configuration indication information in response to detecting overheat of a terminal, where the configuration indication information is indicative of a working-state configuration of an AI model; and adjusting a working state of a corresponding AI model based on the configuration indication information.

Abstract: A blade includes a main body and an edge disposed around a periphery of the main body. A part of the edge includes a soft layer and an intermediate layer connected between the soft layer and the main body. The intermediate layer includes a soft component and a hard component stacked one on another when viewing in a cross-section along a width direction of the blade or along a length direction of the blade.

Abstract: Antimicrobial polymer coating formulations are prepared that protect biological surfaces by treating, reducing, ameliorating, preventing or inhibiting pathogenic microorganism ingress to a human or animal host, reducing the potential for infection, particularly by necrotizing fasciitis originating microorganisms, through use of a polymer coating barrier containing antimicrobial agents that facilitates sustained release of biocidal agents active against such opportunistic microorganisms. Such formulations are effective for inhibiting microbial ingress pertaining to soft tissue and skin tears, abrasions, punctures and surgical wounds, and can be used as in water environments and as a skin protectant sunscreen and insect repellent.

Abstract: This disclosure relates to modified polyurethanes, specifically polyurethanes modified with one or more lipophilic groups, and tough organogels comprising such modified polyurethanes.