Patents by Inventor Xiaoai CHANG

Xiaoai CHANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polypeptide nano-bubbles and preparation method and application thereof
    Publication number: 20190133964
    Abstract: A preparation method for polypeptide nano-bubbles, comprising the following steps: constructing a recombinant plasmid, which includes a Flag tag, an adipose tissue-targeting polypeptide and the coding gene of nano-bubble marker membrane protein CD63; and transfecting the recombinant plasmid into cells which secrete nano-bubbles through lipidosome for culturing, collecting a cell culture solution, and extracting the polypeptide nano-bubbles by ultracentrifugation. The present invention further discloses the polypeptide nano-bubbles and application thereof in the preparation of drugs for treating obesity. The polypeptide nano-bubbles bring great convenience for targeted therapy of anti-obesity drugs. The polypeptide nano-bubbles have good biocompatibility and are capable of carrying different kinds of bioactive substances.
    Type: Application
    Filed: December 26, 2018
    Publication date: May 9, 2019
    Inventors: Yaqin ZHANG, Xiao HAN, Yi YUAN, Hongwei LI, Xiaoai CHANG, Jing PANG, Jingjing WANG, Bin QIAN, Heming WU, Tingting YU, Jindao WU, Ningyuan TANG, Liyong PU, Rufeng XU