Patents by Inventor Xiaoan Ruan

Xiaoan Ruan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel polyketide derivatives and recombinant methods for making same
    Publication number: 20030013662
    Abstract: The invention provides novel erythromycin derivatives in which methyl groups on the macrolactone ring have been substituted with —H, -Et, and/or —OH. The invention also provides reagents such as isolated polynucleotides, vectors comprising the polynucleotides and host cells transformed with the vectors for making the novel compounds. Methods for making the compounds utilizing genetic engineering techniques are also disclosed.
    Type: Application
    Filed: December 11, 2000
    Publication date: January 16, 2003
    Inventors: Leonard Katz, Diane L. Stassi, Richard G. Summers, Xiaoan Ruan, Ana Pereda-Lopez, Stephan J. Kakavas
  • Polyketide derivatives and recombinant methods for making same
    Patent number: 6200813
    Abstract: The invention provides novel erythromycin derivatives in which methyl groups on the macrolactone ring have been substituted with —H, -Et, and/or —OH. The invention also provides reagents such as isolated polynucleotides, vectors comprising the polynucleotides and host cells transformed with the vectors for making the novel compounds. Methods for making the compounds utilizing genetic engineering techniques are also disclosed.
    Type: Grant
    Filed: December 23, 1997
    Date of Patent: March 13, 2001
    Assignee: Abbott Laboratories
    Inventors: Leonard Katz, Diane L. Stassi, Richard G. Summers, Jr., Xiaoan Ruan, Ana Pereda-Lopez, Stephan J. Kakavas
  • Polyketide derivatives and recombinant methods for making same
    Patent number: 6063561
    Abstract: The invention provides novel erythromycin derivatives in which methyl groups on the macrolactone ring have been substituted with --H, -Et, and/or --OH and the ethyl side-chain has been substituted with hydroxymethyl or dihydroxycyclohexylmethyl side-chains. The invention also provides reagents such as isolated polynucleotides, vectors comprising the polynucleotides and host cells transformed with the vectors for making the novel compounds. Methods for making the compounds utilizing genetic engineering techniques are also disclosed.
    Type: Grant
    Filed: May 13, 1998
    Date of Patent: May 16, 2000
    Assignee: Abbott Laboratories
    Inventors: Leonard Katz, Diane L. Stassi, Richard G. Summers, Jr., Xiaoan Ruan, Ana Pereda-Lopez, Stephan J. Kakavas
  • Polyketide derivatives and recombinant methods for making same
    Patent number: 6060234
    Abstract: The invention provides novel erythromycin derivatives in which methyl groups on the macrolactone ring have been substituted with --H, --Et, and/or --OH. The invention also provides reagents such as isolated polynucleotides, vectors comprising the polynucleotides and host cells transformed with the vectors for making the novel compounds. Methods for making the compounds utilizing genetic engineering techniques are also disclosed.
    Type: Grant
    Filed: May 16, 1997
    Date of Patent: May 9, 2000
    Assignee: Abbott Laboratories
    Inventors: Leonard Katz, Diane L. Stassi, Richard G. Summers, Jr., Xiaoan Ruan, Ana Pereda-Lopez, Stephan J. Kakavas