Patents by Inventor Xiaobi Li

Xiaobi Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Dapagliflozin crystalline form and preparation method thereof
    Patent number: 9550747
    Abstract: The present invention relates to a new crystalline form of dapagliflozin represented by formula (I). The crystalline form has a characteristic absorption peak at about 4.318 (20.45) in an X-ray powder diffraction pattern shown by angle 2 theta and interplanar spacing (value d). It can be prepared by dissolving dapagliflozin in good organic solvents, adding poor solvents, stirring to crystallization, filtering and drying. The new crystalline form of dapagliflozin of the present invention has the following superior features: good solubility, low hygroscopicity, high stability and good preparation reproducibility.
    Type: Grant
    Filed: January 19, 2015
    Date of Patent: January 24, 2017
    Assignee: Jiangsu Hansoh Pharmaceutical Group Co., Ltd.
    Inventors: Xifeng Zhu, Xiaobi Li, Tiancheng Zhang, Fuping Yuan
  • DAPAGLIFLOZIN CRYSTALLINE FORM AND PREPARATION METHOD THEREOF
    Publication number: 20160347731
    Abstract: A crystalline form of dapagliflozin represented by formula (I) is provided. The crystalline form has a characteristic absorption peak in an X-ray powder diffraction pattern at a diffraction angle 2? and interplanar spacing (value d) at about 4.318 (20.45) in an X-ray powder diffraction pattern. The crystalline form can be prepared by dissolving dapagliflozin in good organic solvents, adding poor solvents, stirring to crystallization, filtering and drying. The provided crystalline form of dapagliflozin has the following features: good solubility, low hygroscopicity, high stability and good preparation reproducibility.
    Type: Application
    Filed: January 19, 2015
    Publication date: December 1, 2016
    Inventors: Xifeng Zhu, Xiaobi Li, Tiancheng Zhang, Fuping Yuan