Patents by Inventor Xiaobo HAO

Xiaobo HAO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240132581
    Abstract: A bispecific antibody and a monoclonal antibody against human thymic stromal lymphopoietin (TSLP), and a use thereof.
    Type: Application
    Filed: June 16, 2021
    Publication date: April 25, 2024
    Inventors: Xueping ZHANG, Zhigang LIU, Xiaowei ZHOU, Junjie HU, Xiaobo HAO, Yulan LIU
  • Patent number: 11956147
    Abstract: A data transmission method, apparatus, and device, and a computer storage medium are provided. The method includes: obtaining an application packet of a target application; transmitting the application packet to a first routing device by using a network data channel, and transmitting, by using the first routing device, the application packet to a proxy server; meanwhile, transmitting the same application packet to a second routing device by using a short-range wireless data channel different from the network data channel, and transmitting, by using the second routing device, the application packet to the proxy server. The proxy server performs, a deduplication mechanism on the application packet and transmit the application packet to an application server corresponding to the target application.
    Type: Grant
    Filed: June 24, 2021
    Date of Patent: April 9, 2024
    Assignee: TENCENT TECHNOLOGY (SHENZHEN) COMPANY LIMITED
    Inventors: Jingjing Hao, Dan Zhang, Binhui Ning, Xiaobo Hu, Feihu Sun, Liuteng Li, Jianbo Xu, Zhenlin Huang, Shuai Ma, Guoqiang Che
  • Patent number: 11897960
    Abstract: Disclosed in the present application are an antibody or an antigen-binding portion thereof binding to human IL-4R, a polynucleotide encoding the antibody or antigen-binding portion thereof, a vector comprising the polynucleotide, a host cell comprising the polynucleotide or vector, a method for preparing and purifying the antibody, and the use of the antibody or antigen-binding portion thereof.
    Type: Grant
    Filed: August 13, 2018
    Date of Patent: February 13, 2024
    Assignees: Beijing Wisdomab Biotechnology Co., Ltd, Genrix (Shanghai) Biopharmaceutical Co. Ltd., Chongqing Genrix Biopharmaceutical Co., Ltd.
    Inventors: Zhigang Liu, Yulan Liu, Xiaobo Hao, Lei Jiang, Jingjing Guo
  • Patent number: 11773155
    Abstract: The present application provides a bispecific antibody against rabies virus, and an application thereof. The bispecific antibody comprises two antigen-binding fragments binding to different epitopes of G protein of rabies virus, and has rabies virus neutralization activity.
    Type: Grant
    Filed: August 1, 2019
    Date of Patent: October 3, 2023
    Assignees: Beijing Wisdomab Biotechnology Co., ltd, GENRIX (Shanghai) Biopharmaceutical Co., Ltd., Chongqing GENRIX Biopharmaceutical Co., Ltd.
    Inventors: Zhigang Liu, Xiaobo Hao, Yulan Liu, Jingjing Guo
  • Publication number: 20230071422
    Abstract: Provided is a bispecific antibody comprising an antigen-binding portion for human CD3E and/or an antigen-binding portion for human CD123. Further provided are the medical and biological uses of the bispecific antibody.
    Type: Application
    Filed: March 30, 2020
    Publication date: March 9, 2023
    Inventors: Zhigang Liu, Xiaobo HAO, Xueping ZHANG, Yulan LIU, Jingjing GUO
  • Publication number: 20230017667
    Abstract: Embodiments of this application disclose a data recommendation method performed by a computer device. The data recommendation method includes: obtaining a service object set associated with a target user in a plurality of fields in response to a data recommendation request for the target user in a target field, performing cross-field cross-encoding on the plurality of fields and the service object set to obtain a target field interest feature of the target user in the target field; obtaining to-be-recommended service object features of a plurality of to-be-recommended service objects in the target field; and obtaining a target to-be-recommended service object feature matching with the target field interest feature of the target user from the to-be-recommended service object features, and returning a target to-be-recommended service object corresponding to the target to-be-recommended service object feature to the target user.
    Type: Application
    Filed: September 19, 2022
    Publication date: January 19, 2023
    Inventors: Xiaobo Hao, Kaikai Ge, Yudan Liu, Linyao Tang, Xu Zhang, Ruobing Xie, Leyu Lin
  • Publication number: 20230009814
    Abstract: Embodiments of this application provide a for training an information recommendation model. The method includes: obtaining historical user behavior data in a plurality of product domains; generating candidate sample data of one or more target product domains according to the historical user behavior data by using a generative model; performing user-specific authenticity sample discrimination on candidate sample data of the target product domains and actual user click sample data by using a discriminative model, to obtain a discrimination result; and performing adversarial training on the generative model and the discriminative model according to the discrimination result, to obtain a trained generative adversarial network as an information recommendation model for a to-be-expanded product domain in the plurality of product domains.
    Type: Application
    Filed: September 19, 2022
    Publication date: January 12, 2023
    Inventors: Xiaobo HAO, Kaikai GE, Yudan LIU, Linyao TANG, Ruobing XIE, Xu ZHANG, Leyu LIN
  • Publication number: 20220081485
    Abstract: Disclosed in the present application are an antibody or an antigen-binding portion thereof binding to human IL-4R, a polynucleotide encoding the antibody or antigen-binding portion thereof, a vector comprising the polynucleotide, a host cell comprising the polynucleotide or vector, a method for preparing and purifying the antibody, and the use of the antibody or antigen-binding portion thereof.
    Type: Application
    Filed: August 13, 2018
    Publication date: March 17, 2022
    Inventors: Zhigang LIU, Yulan LIU, Xiaobo HAO, Lei JIANG, Jingjing GUO
  • Publication number: 20210340224
    Abstract: The present application provides a bispecific antibody against rabies virus, and an application thereof. The bispecific antibody comprises two antigen-binding fragments binding to different epitopes of G protein of rabies virus, and has rabies virus neutralization activity.
    Type: Application
    Filed: August 1, 2019
    Publication date: November 4, 2021
    Inventors: Zhigang LIU, Xiaobo HAO, Yulan LIU, Jingjing GUO
  • Publication number: 20210326674
    Abstract: This application discloses a content recommendation method performed at a computer device and belongs to the field of artificial intelligence. The method includes: acquiring a target user vector of a target user; determining n groups of seed user vectors according to the target user vector, each group of seed user vectors corresponding to a respective piece of candidate recommendation content; invoking a look-alike model to calculate a similarity between the target user vector and each group of seed user vectors, the look-alike model being used for calculating a similarity between user vectors based on an attention mechanism; and determining, among the n pieces of candidate recommendation content, target content to be recommended to the target user according to the respective similarities of the corresponding n groups of seed user vectors. This application can resolve a problem of relatively low accuracy of a recommendation method in the related art.
    Type: Application
    Filed: June 29, 2021
    Publication date: October 21, 2021
    Inventors: Yudan Liu, Kaikai Ge, Xu Zhang, Leyu Lin, Xin Chen, Xiaobo Hao, Wei Wang, Kai Zhuang, Su Yan, Zhida Pan, Linyao Tang, Jing Zhang
  • Publication number: 20210312486
    Abstract: A method for determining a delivery range, including: obtaining historical behavior data in multiple territorial blocks and historical order data of multiple merchants (101); obtaining a target merchant set in each territorial block according to the historical behavior data in the multiple territorial blocks and the historical order data of the multiple merchants (102); and determining a delivery range for each merchant based on the target merchant set in each territorial block (103).
    Type: Application
    Filed: December 19, 2018
    Publication date: October 7, 2021
    Inventors: Xuetao DING, Runfeng ZHANG, Dong JIA, Renqing HE, Zhengang GUO, Xiaobo HAO
  • Patent number: 10392436
    Abstract: The present application discloses a novel anti-human IL-17 monoclonal antibody obtained by phage antibody library screening and genetic engineering, or a functional fragment thereof, a polynucleotide encoding the monoclonal antibody or the functional fragment thereof, a vector comprising the polynucleotide, a host cell comprising the polynucleotide or vector, a method for preparing and purifying the antibody, and use of the antibody or the functional fragment thereof.
    Type: Grant
    Filed: February 29, 2016
    Date of Patent: August 27, 2019
    Assignees: BEIJING BETTERMAB BIOTECHNOLOGY CO., LTD, BEIJING WISDOMAB BIOTECHNOLOGY CO., LTD, GENRIX (SHANGHAI) BIOPHARMACEUTICAL CO. LTD., CHONGQING GENRIX BIOPHARMACEUTICAL CO., LTD.
    Inventors: Zhigang Liu, Shijie Shen, Yulan Liu, Jingjing Guo, Xiaobo Hao
  • Publication number: 20170327571
    Abstract: The present application discloses a novel anti-human IL-17 monoclonal antibody obtained by phage antibody library screening and genetic engineering, or a functional fragment thereof, a polynucleotide encoding the monoclonal antibody or the functional fragment thereof, a vector comprising the polynucleotide, a host cell comprising the polynucleotide or vector, a method for preparing and purifying the antibody, and use of the antibody or the functional fragment thereof.
    Type: Application
    Filed: February 29, 2016
    Publication date: November 16, 2017
    Inventors: Zhigang LIU, Shijie SHEN, Yulan LIU, Jingjing GUO, Xiaobo HAO