Patents by Inventor Xiaobo XI

Xiaobo XI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • A GENETICALLY MODIFIED CELL LINE PRODUCING A RECOMBINANT GLYCOPROTEIN HAVING A MANNOSE-TERMINATED N-GLYCAN
    Publication number: 20240167010
    Abstract: Provided are a genetically modified cell line producing a recombinant glycoprotein having a mannose-terminated N-glycan and a method for producing the recombinant glycoprotein or a method for generating the cell, clone or cell line. The cell line comprises an insertion of less than 600 bp in the coding region of a chromosomal sequence encoding MGAT1.
    Type: Application
    Filed: April 21, 2021
    Publication date: May 23, 2024
    Applicant: WUXI BIOLOGICS IRELAND LIMITED
    Inventors: Liqin XU, Fenglin WANG, Yangfang ZHOU, Yangzi PENG, Jiexing CAI, Weichang ZHOU, Xiaobo XI, Weiwen WANG, Tingting WANG, Chunsheng YANG, Quanmin CHEN, Jeremy GUO
  • A GENETICALLY MODIFIED CELL LINE PRODUCING A RECOMBINANT GLYCOPROTEIN HAVING A MANNOSE-TERMINATED N-GLYCAN
    Publication number: 20230287378
    Abstract: Provided are a genetically modified cell line producing a recombinant glycoprotein having a mannose-terminated N-glycan and a method for producing the recombinant glycoprotein or a method for generating the cell, clone or cell line. The cell line comprises an insertion of less than 600 bp in the coding region of a chromosomal sequence encoding MGAT1.
    Type: Application
    Filed: April 21, 2021
    Publication date: September 14, 2023
    Applicant: WUXI BIOLOGICS IRELAND LIMITED
    Inventors: Liqin XU, Fenglin WANG, Yangfang ZHOU, Yangzi PENG, Jiexing CAI, Weichang ZHOU, Xiaobo XI, Weiwen WANG, Tingting WANG, Chunsheng YANG, Quanmin CHEN, Jeremy GUO
  • MICROCAPSULE-BASED VACCINE
    Publication number: 20210308258
    Abstract: A vaccine comprising antigen and a matrix of biodegradable polymer blend, wherein the polymer blend comprises hydrophobic polymer and amphiphilic block copolymer, and the vaccine exists in form of microcapsules that comprise a multi-cavity structure inside, and has an average particle diameter of preferably 10-100 ?m and more preferably 30-60 ?m, and is prepared by means of the following method: making porous microspheres from the polymer blend, then mixing the porous microspheres with antigen-containing solution, and then sealing openings of porous microspheres that have been loaded with the antigen-containing solution to form an opening-sealed microcapsule loaded with the antigen.
    Type: Application
    Filed: August 16, 2019
    Publication date: October 7, 2021
    Inventors: Guanghui MA, Wei WEI, Xiaobo XI, Tong YE, Xiangming NA, Shuang QING