Patents by Inventor Xiaochen ZHAO
Xiaochen ZHAO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12276242Abstract: Provided is an intake bypass recirculation structure capable of silencing, including: an intake bypass recirculation structure body and a structure-conducted silencing device. An intake bypass recirculation cavity is provided on the intake bypass recirculation structure body. An inlet of the intake bypass recirculation structure and an outlet of the intake bypass recirculation structure that are provided on the intake bypass recirculation structure body are each connected to the intake bypass recirculation cavity. The structure-conducted silencing device is disposed inside the intake bypass recirculation cavity. In this application, during working, noise generated by a compressor is transmitted into the intake bypass recirculation cavity via an inlet of the intake bypass recirculation structure, and transmitted outside via the outlet of the intake bypass recirculation structure.Type: GrantFiled: December 18, 2024Date of Patent: April 15, 2025Assignee: Harbin Engineering UniversityInventors: Yipeng Cao, Yao Song, Chen Liu, Xiaochen Zhao, Jiaxuan Lin, Shaoran Du, Jie Yang, Jie Guo, Xinyu Zhang
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Publication number: 20250057948Abstract: The disclosure provides pharmaceutical compositions comprising an anti-PD-1 antibody or an anti-PD-L1 antibody. In some aspects, the pharmaceutical compositions are formulated for subcutaneous delivery. In some aspects, the pharmaceutical compositions further comprise an endoglycosidase hydrolase enzyme. Other aspects of the present disclosure are directed to methods of subcutaneously delivering a pharmaceutical composition comprising an anti-PD-1 antibody or an anti-PD-L1 antibody.Type: ApplicationFiled: June 6, 2024Publication date: February 20, 2025Applicants: Bristol-Myers Squibb Company, Halozyme, Inc.Inventors: Masano HUANG, Thomas Arthur HABY, Mehrnaz KHOSSRAVI, Scott Aaron HART, Rao Venkatramana MANTRI, Heather Elizabeth VEZINA, Amit ROY, Bindu Purnima MURTHY, Urvi Ashish ARAS, Kinjal SANGHAVI, Xiaochen ZHAO, Akintunde BELLO
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Publication number: 20240252629Abstract: The disclosure provides pharmaceutical compositions comprising an anti-PD-1 antibody or an anti-PD-L1 antibody. In some aspects, the pharmaceutical compositions are formulated for subcutaneous delivery. In some aspects, the pharmaceutical compositions further comprise an endoglycosidase hydrolase enzyme. Other aspects of the present disclosure are directed to methods of subcutaneously delivering a pharmaceutical composition comprising an anti-PD-1 antibody or an anti-PD-L1 antibody.Type: ApplicationFiled: January 25, 2024Publication date: August 1, 2024Applicants: Bristol-Myers Squibb Company, Halozyme, Inc.Inventors: Masano HUANG, Thomas Arthur HABY, Mehrnaz KHOSSRAVI, Scott Aaron HART, Rao Venkatramana MANTRI, Heather Elizabeth VEZINA, Amit ROY, Bindu Purnima MURTHY, Urvi Ashish ARAS, Kinjal SANGHAVI, Xiaochen ZHAO, Akintunde BELLO
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Patent number: 11946485Abstract: Some embodiments of the disclosure provide an air intake bypass recirculation structure with adjustable air entraining amount and controllable broadband noise which includes main body of the air intake bypass recirculation structure and an air entraining amount adjusting structure. In some examples, an air intake bypass recirculation cavity is formed in the main body of the air intake bypass recirculation structure. An air inlet of an air intake pipe and an air outlet of the air intake pipe are formed in two ends of the main body of the air intake bypass recirculation structure respectively. An airflow inlet of the air intake bypass recirculation structure and an airflow outlet of the air intake bypass recirculation structure are formed in the inner side of the main body of the air intake bypass recirculation structure. The air entraining amount adjusting structure is arranged in the air intake bypass recirculation cavity.Type: GrantFiled: August 14, 2023Date of Patent: April 2, 2024Assignee: Harbin Engineering UniversityInventors: Chen Liu, Zequn Ma, Yipeng Cao, Runze Zhang, Xinyu Zhang, Wenping Zhang, Jie Yang, Changhong Sun, Jie Guo, Xiaochen Zhao, Gongmin Liu
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Patent number: 11905916Abstract: A turbocharger air intake silencer with adjustable cavity space structures is provided. The turbocharger air intake silencer comprises a silencer connecting flange and a first resonator device. The first resonator device comprises a first silencer sealing plate, a first annular sound absorption cavity body, a first rotary table, a first rotary steering gear and a first valve. A first sound absorption cavity is enclosed by the first silencer sealing plate, the first annular sound absorption cavity body, the first valve and the first rotary table. A first sound absorption cavity inlet pipe is arranged beside the first sound absorption cavity. The first sound absorption cavity and the first sound absorption cavity inlet pipe form a Helmholtz resonator. The first rotary steering gear is mounted on the silencer connecting flange. The rotary steering gear is connected with a first rotary rack.Type: GrantFiled: August 1, 2023Date of Patent: February 20, 2024Assignee: HARBIN ENGINEERING UNIVERSITYInventors: Yipeng Cao, Zequn Ma, Chen Liu, Runze Zhang, Xinyu Zhang, Wenping Zhang, Zhuoyan Feng, Yuan Gao, Xiaochen Zhao, Gongmin Liu
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Publication number: 20240052849Abstract: Some embodiments of the disclosure provide an air intake bypass recirculation structure with adjustable air entraining amount and controllable broadband noise which includes main body of the air intake bypass recirculation structure and an air entraining amount adjusting structure. In some examples, an air intake bypass recirculation cavity is formed in the main body of the air intake bypass recirculation structure. An air inlet of an air intake pipe and an air outlet of the air intake pipe are formed in two ends of the main body of the air intake bypass recirculation structure respectively. An airflow inlet of the air intake bypass recirculation structure and an airflow outlet of the air intake bypass recirculation structure are formed in the inner side of the main body of the air intake bypass recirculation structure. The air entraining amount adjusting structure is arranged in the air intake bypass recirculation cavity.Type: ApplicationFiled: August 14, 2023Publication date: February 15, 2024Applicant: Harbin Engineering UniversityInventors: Chen LIU, Zequn MA, Yipeng CAO, Runze ZHANG, Xinyu ZHANG, Wenping ZHANG, Jie YANG, Changhong SUN, Jie GUO, Xiaochen ZHAO, Gongmin LIU
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Publication number: 20240044306Abstract: A turbocharger air intake silencer with adjustable cavity space structures is provided. The turbocharger air intake silencer comprises a silencer connecting flange and a first resonator device. The first resonator device comprises a first silencer sealing plate, a first annular sound absorption cavity body, a first rotary table, a first rotary steering gear and a first valve. A first sound absorption cavity is enclosed by the first silencer sealing plate, the first annular sound absorption cavity body, the first valve and the first rotary table. A first sound absorption cavity inlet pipe is arranged beside the first sound absorption cavity. The first sound absorption cavity and the first sound absorption cavity inlet pipe form a Helmholtz resonator. The first rotary steering gear is mounted on the silencer connecting flange. The rotary steering gear is connected with a first rotary rack.Type: ApplicationFiled: August 1, 2023Publication date: February 8, 2024Inventors: YIPENG CAO, ZEQUN MA, CHEN LIU, RUNZE ZHANG, XINYU ZHANG, WENPING ZHANG, ZHUOYAN FENG, YUAN GAO, XIAOCHEN ZHAO, GONGMIN LIU
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Publication number: 20240024471Abstract: The disclosure provides pharmaceutical compositions comprising an anti-PD-1 antibody or an anti-PD-L1 antibody. In some aspects, the pharmaceutical compositions are formulated for subcutaneous delivery. In some aspects, the pharmaceutical compositions further comprise an endoglycosidase hydrolase enzyme. Other aspects of the present disclosure are directed to methods of subcutaneously delivering a pharmaceutical composition comprising an anti-PD-1 antibody or an anti-PD-L1 antibody.Type: ApplicationFiled: August 21, 2023Publication date: January 25, 2024Applicants: Bristol-Myers Squibb Company, Halozyme, Inc.Inventors: Masano HUANG, Thomas Arthur HABY, Mehrnaz KHOSSRAVI, Scott Aaron HART, Rao Venkatramana MANTRI, Heather Elizabeth VEZINA, Amit ROY, Bindu Purnima MURTHY, Urvi Ashish ARAS, Kinjal SANGHAVI, Xiaochen ZHAO, Akintunde BELLO
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Publication number: 20240000934Abstract: The disclosure provides pharmaceutical compositions comprising an antibody and at least two antioxidants. In some aspects, pharmaceutical composition is formulated for subcutaneous delivery. In some aspects, the pharmaceutical composition further comprises an endoglycosidase hydrolase enzyme. Other aspects of the present disclosure are directed to methods of subcutaneously delivering the pharmaceutical composition.Type: ApplicationFiled: August 21, 2023Publication date: January 4, 2024Applicants: Bristol-Myers Squibb Company, Halozyme, Inc.Inventors: Masano HUANG, Thomas Arthur HABY, Mehrnaz KHOSSRAVI, Scott Aaron HART, Rao Venkatramana MANTRI, Heather Elizabeth VEZINA, Amit ROY, Bindu Purnima MURTHY, Urvi Ashish ARAS, Kinjal SANGHAVI, Xiaochen ZHAO, Akintunde BELLO
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Publication number: 20220233689Abstract: The disclosure provides pharmaceutical compositions comprising an anti-PD-1 antibody or an anti-PD-L1 antibody. In some aspects, the pharmaceutical compositions are formulated for subcutaneous delivery. In some aspects, the pharmaceutical compositions further comprise an endoglycosidase hydrolase enzyme. Other aspects of the present disclosure are directed to methods of subcutaneously delivering a pharmaceutical composition comprising an anti-PD-1 antibody or an anti-PD-L1 antibody.Type: ApplicationFiled: December 27, 2021Publication date: July 28, 2022Applicants: Bristol-Myers Squibb Company, Halozyme, Inc.Inventors: Masano Huang, Thomas Arthur Haby, Mehrnaz KHOSSRAVI, Scott Aaron HART, Rao Venkatramana MANTRI, Heather Elizabeth VEZINA, Amit ROY, Bindu Purnima MURTHY, Urvi Ashish ARAS, Kinjal SANGHAVI, Xiaochen ZHAO, Akintunde BELLO
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Publication number: 20220233693Abstract: The disclosure provides pharmaceutical compositions comprising an antibody and at least two antioxidants. In some aspects, pharmaceutical composition is formulated for subcutaneous delivery. In some aspects, the pharmaceutical composition further comprises an endoglycosidase hydrolase enzyme. Other aspects of the present disclosure are directed to methods of subcutaneously delivering the pharmaceutical composition.Type: ApplicationFiled: December 27, 2021Publication date: July 28, 2022Applicants: Bristol-Myers Squibb Company, Halozyme, Inc.Inventors: Masano HUANG, Thomas Arthur HABY, Mehrnaz KHOSSRAVI, Scott Aaron HART, Rao Venkatramana MANTRI, Heather Elizabeth VEZINA, Amit ROY, Bindu Purnima MURTHY, Urvi Ashish ARAS, Kinjal SANGHAVI, Xiaochen ZHAO, Akintunde BELLO