Patents by Inventor Xiaocheng Jiang
Xiaocheng Jiang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11976557Abstract: The present disclosure provides a coal bump control method for sectional hydraulic fracturing regions of a near vertical ultra thick coal seam. The method includes: deepening a main shaft from a mining level to a fracturing level; excavating a cross-hole from a roof rock layer of a coal seam at the fracturing level to enter a coal seam being mined, and excavating a roadway along the strike of the coal seam; and drilling hydraulic fracturing boreholes in a dedicated fracturing roadway along an inclination angle of the coal seam to the coal seam above the roadway, wherein the length of the borehole makes the borehole in communication with a goaf, and the spacing of the boreholes along the strike and the sectional spacing of the boreholes in an inclination direction are designed according to the parameters of fracturing equipments and the fracturing length.Type: GrantFiled: August 18, 2022Date of Patent: May 7, 2024Assignees: University of Science and Technology Beijing, North China Institute of Science and Technology, Beijing Anke Xingye Science and Technology Co., Ltd.Inventors: Sitao Zhu, Gaoang Wang, Fuxing Jiang, Gang Yao, Tao Zhou, Jinhai Liu, Huan Li, Zhen Kong, Qingbo He, Xiaocheng Qu, Quande Wei, Yitong Huang, Shaohua Sun
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Publication number: 20220299466Abstract: A sensor includes a bio-recognition module and a transducer module having a dock sized and shaped to receive the bio-recognition module. The bio-recognition modules comprise a hydrogel matrix having bio-recognition elements embedded therein. The bio-recognition elements cause a particular biochemical input to engage in an interaction that generates a perturbation in an electric field within the bio-recognition module. The transducer module transduces this perturbation into an electrical signal that is provided at an output of the transducer module. This electrical signal indicates occurrence of the interaction.Type: ApplicationFiled: August 11, 2020Publication date: September 22, 2022Inventors: Xiaocheng JIANG, Xiaochuan DAI, Richard VO
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Publication number: 20200122146Abstract: Methods and systems for isolating platelet-associated nucleated target cells, e.g., such as circulating epithelial cells, circulating tumor cells (CTCs), circulating endothelial cells (CECs), circulating stem cells (CSCs), neutrophils, and macrophages, from sample fluids, e.g., biological fluids, such as blood, bone marrow, plural effusions, and ascites fluid, are described. The methods include obtaining a cell capture chamber including a plurality of binding moieties bound to one or more walls of the chamber, wherein the binding moieties specifically bind to platelets; flowing the sample fluid through the cell capture chamber under conditions that allow the binding moieties to bind to any platelet-associated nucleated target cells in the sample to form complexes; and separating and collecting platelet-associated nucleated target cells from the complexes.Type: ApplicationFiled: August 22, 2019Publication date: April 23, 2020Inventors: Mehmet Toner, Shannon Stott, Eduardo Reategui, Xiaocheng Jiang
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Patent number: 10391491Abstract: Methods and systems for isolating platelet-associated nucleated target cells, e.g., such as circulating epithelial cells, circulating tumor cells (CTCs), circulating endothelial cells (CECs), circulating stem cells (CSCs), neutrophils, and macrophages, from sample fluids, e.g., biological fluids, such as blood, bone marrow, plural effusions, and ascites fluid, are described. The methods include obtaining a cell capture chamber including a plurality of binding moieties bound to one or more walls of the chamber, wherein the binding moieties specifically bind to platelets; flowing the sample fluid through the cell capture chamber under conditions that allow the binding moieties to bind to any platelet-associated nucleated target cells in the sample to form complexes; and separating and collecting platelet-associated nucleated target cells from the complexes.Type: GrantFiled: August 7, 2015Date of Patent: August 27, 2019Assignee: The General Hospital CorporationInventors: Mehmet Toner, Shannon Stott, Eduardo Reategui, Xiaocheng Jiang
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Publication number: 20180088079Abstract: The present invention generally relates to nanoscale wires and other nanomaterials, including nanoscale wires used as sensors, including nanoscale wires comprising semiconductor nanowires, carbon nanotubes, graphene, or metal oxide nanomaterials. Certain aspects of the invention are generally directed to polymer coating on nanoscale wires that can be used to increase sensitivity to analytes, for example, in physiologically relevant conditions. For example, the polymer may have an average pore size comparable in size to an analyte. Accordingly, in some cases, the nanoscale wires can be used as sensors, even in ionic solutions, e.g., under physiologically relevant conditions. Other aspects of the invention include assays, sensors, kits, and/or other devices that include such nanoscale wires, methods of making and/or using such nanoscale wires, or the like.Type: ApplicationFiled: April 1, 2016Publication date: March 29, 2018Inventors: Charles M. Lieber, Ning Gao, Wei Zhou, Xiaocheng Jiang, Teng Gao, Xiao Yang
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Publication number: 20170225166Abstract: Methods and systems for isolating platelet-associated nucleated target cells, e.g., such as circulating epithelial cells, circulating tumor cells (CTCs), circulating endothelial cells (CECs), circulating stem cells (CSCs), neutrophils, and macrophages, from sample fluids, e.g., biological fluids, such as blood, bone marrow, plural effusions, and ascites fluid, are described. The methods include obtaining a cell capture chamber including a plurality of binding moieties bound to one or more walls of the chamber, wherein the binding moieties specifically bind to platelets; flowing the sample fluid through the cell capture chamber under conditions that allow the binding moieties to bind to any platelet-associated nucleated target cells in the sample to form complexes; and separating and collecting platelet-associated nucleated target cells from the complexes.Type: ApplicationFiled: August 7, 2015Publication date: August 10, 2017Inventors: Mehmet Toner, Shannon Stott, Eduardo Reategui, Xiaocheng Jiang
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Patent number: 9595685Abstract: The present invention generally relates to nanotechnology, including field effect transistors and other devices used as sensors (for example, for electrophysiological studies), nanotube structures, and applications. Certain aspects of the present invention are generally directed to transistors such as field effect transistors, and other similar devices. In one set of embodiments, a field effect transistor is used where a nanoscale wire, for example, a silicon nanowire, acts as a transistor channel connecting a source electrode to a drain electrode. In some cases, a portion of the transistor channel is exposed to an environment that is to be determined, for example, the interior or cytosol of a cell. A nanotube or other suitable fluidic channel may be extended from the transistor channel into a suitable environment, such as a contained environment within a cell, so that the environment is in electrical communication with the transistor channel via the fluidic channel.Type: GrantFiled: June 7, 2012Date of Patent: March 14, 2017Assignee: President and Fellows of Harvard CollegeInventors: Charles M. Lieber, Xiaojie Duan, Ruixuan Gao, Ping Xie, Xiaocheng Jiang
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Publication number: 20140184196Abstract: The present invention generally relates to nanotechnology, including field effect transistors and other devices used as sensors (for example, for electrophysiological studies), nanotube structures, and applications. Certain aspects of the present invention are generally directed to transistors such as field effect transistors, and other similar devices. In one set of embodiments, a field effect transistor is used where a nanoscale wire, for example, a silicon nanowire, acts as a transistor channel connecting a source electrode to a drain electrode. In some cases, a portion of the transistor channel is exposed to an environment that is to be determined, for example, the interior or cytosol of a cell. A nanotube or other suitable fluidic channel may be extended from the transistor channel into a suitable environment, such as a contained environment within a cell, so that the environment is in electrical communication with the transistor channel via the fluidic channel.Type: ApplicationFiled: June 7, 2012Publication date: July 3, 2014Applicant: President and Fellows of Harvard CollegeInventors: Charles M. Lieber, Xiaojie Duan, Ruixuan Gao, Ping Xie, Xiaocheng Jiang
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Patent number: 8058640Abstract: The present invention generally relates to nanotechnology and, in particular, to branched nanoscale wires. In some cases, the branched nanoscale wires may be produced using vapor-phase and/or solution-phase synthesis. Branched nanoscale wires may be grown by depositing nanoparticles onto a nanoscale wire, and segments or “branches” can then be grown from the nanoparticles. The nanoscale wire may be any nanoscale wire, for example, a semiconductor nanoscale wire, a nanoscale wire having a core and a shell. The segments may be of the same, or of different materials, than the nanoscale wire, for example, semiconductor/metal, semiconductor/semiconductor. The junction between the segment and the nanoscale wire, in some cases, is epitaxial. In one embodiment, the nanoparticles are adsorbed onto the nanoscale wire by immobilizing a positively-charged entity, such as polylysine, to the nanoscale wire, and exposing it to the nanoparticles.Type: GrantFiled: September 11, 2007Date of Patent: November 15, 2011Assignee: President and Fellows of Harvard CollegeInventors: Charles M. Lieber, Bozhi Tian, Xiaocheng Jiang
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Publication number: 20110042641Abstract: The present invention generally relates to nanotechnology and, in particular, to branched nanoscale wires cases, the branched nanoscale wires may be produced using vapor-phase and/or solution-phase synthesis. Branched nanoscale wires may be grown by depositing nanoparticles onto a nanoscale wire, and segments or “branches” can then be grown from the nanoparticles. The nanoscale wire may be any nanoscale wire, for example, a semiconductor nanoscale wire, a nanoscale wire having a core and a shell. The segments may be of the same, or of different materials, than the nanoscale wire, for example, semiconductor/metal, semiconductor/semiconductor. The junction between the segment and the nanoscale wire, in some cases, is epitaxial. In one embodiment, the nanoparticles are adsorbed onto the nanoscale wire by immobilizing a positively-charged entity, such as polylysine, to the nanoscale wire, and exposing it to the nanoparticles.Type: ApplicationFiled: September 11, 2007Publication date: February 24, 2011Applicant: President and Fellows of Harvard CollegeInventors: Charles M. Lieber, Bozhi Tian, Xiaocheng Jiang