Patents by Inventor Xiaochun Dong

Xiaochun Dong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12269808
    Abstract: An amino dithioperacid thioester compound, a preparation method therefor, and use thereof. The structural formula of compound is as shown in formula I: wherein m=1-11, X is a nitrogen-containing aliphatic heterocyclic ring, and a nitrogen atom in the aliphatic heterocyclic ring is connected to a carbon atom of a thiocarbonyl group. The compounds disclosed by the invention are found to be capable of relieving muscular atrophy and lipolysis caused by cancer cachexia through in-vivo and in-vitro experiments. The compounds are also capable of obviously relieving weight and food intake reduction caused by cancer cachexia in animal experiments, so that the carbamo(dithioperoxo)thioates compounds have the effect on resisting cancer cachexia, can be applied to the treatment of cancer cachexia and related diseases, and become one kind of ideal cancer cachexia treatment medicament.
    Type: Grant
    Filed: November 27, 2020
    Date of Patent: April 8, 2025
    Assignees: FUDAN UNIVERSITY, EAST CHINA NORMAL UNIVERSITY
    Inventors: Weili Zhao, Xiongwen Zhang, Xiaochun Dong, Yiwei Li, Shuang Xu, Shanshan Lu, Guangyu Lin, Kedan Gu
  • Publication number: 20220396557
    Abstract: An amino dithioperacid thioester compound, a preparation method therefor, and use thereof. The structural formula of compound is as shown in formula I: wherein m=1-11, X is a nitrogen-containing aliphatic heterocyclic ring, and a nitrogen atom in the aliphatic heterocyclic ring is connected to a carbon atom of a thiocarbonyl group. The compounds disclosed by the invention are found to be capable of relieving muscular atrophy and lipolysis caused by cancer cachexia through in-vivo and in-vitro experiments. The compounds are also capable of obviously relieving weight and food intake reduction caused by cancer cachexia in animal experiments, so that the carbamo(dithioperoxo)thioates compounds have the effect on resisting cancer cachexia, can be applied to the treatment of cancer cachexia and related diseases, and become one kind of ideal cancer cachexia treatment medicament.
    Type: Application
    Filed: November 27, 2020
    Publication date: December 15, 2022
    Inventors: Weili ZHAO, Xiongwen ZHANG, Xiaochun DONG, Yiwei LI, Shuang XU, Shanshan LU, Guangyu LIN, Kedan GU
  • Patent number: 8061841
    Abstract: A customizing equipment for individualized contact lenses comprises an uniform illumination system, a gray image generation system, a projection optical system, a stage system and an alignment system, among which the uniform illumination system generates uniform parallel illuminative light, which generates gray images through the gray image generator controlled by a computer after going through the gray image generation system according to detection results of aberration of human eyes, and images on the image plane of given radius of curvature with photoresist on the samples' surface, which is fixed on the stage system and adjusted to the correct position through the alignment system, after the gray images are zoomed and the curvature of the image field is corrected through the projection optical system, so that the photoresist on the samples' surface will be exposed according to the gray levels of the gray images, after which the exposed samples are developed and etched to obtain the device with continuous e
    Type: Grant
    Filed: September 7, 2007
    Date of Patent: November 22, 2011
    Assignee: Institute of Optics & Electronics, Chinese Academy of Sciences
    Inventors: Yudong Zhang, Jian Wang, Lixin Zhao, Song Hu, Xiaochun Dong, Xuejun Rao, Hongtao Gao, Yun Dai
  • Publication number: 20080062390
    Abstract: A customizing equipment for individualized contact lenses comprises an uniform illumination system, a gray image generation system, a projection optical system, a stage system and an alignment system, among which the uniform illumination system generates uniform parallel illuminative light, which generates gray images through the gray image generator controlled by a computer after going through the gray image generation system according to detection results of aberration of human eyes, and images on the image plane of given radius of curvature with photoresist on the samples' surface, which is fixed on the stage system and adjusted to the correct position through the alignment system, after the gray images are zoomed and the curvature of the image field is corrected through the projection optical system, so that the photoresist on the samples' surface will be exposed according to the gray levels of the gray images, after which the exposed samples are developed and etched to obtain the device with continuous e
    Type: Application
    Filed: September 7, 2007
    Publication date: March 13, 2008
    Inventors: Yudong Zhang, Jian Wang, Lixin Zhao, Song Hu, Xiaochun Dong, Xuejun Rao, Hongtao Gao, Yun Dai