Patents by Inventor Xiaochun Han

Xiaochun Han has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250230163
    Abstract: The present disclosure relates generally to solid forms of the compound of Formula I: Also disclosed are pharmaceutical compositions comprising said solid forms and methods of making said solid forms. The solid forms of the disclosure are useful in treating or preventing human immunodeficiency virus (HIV) infection.
    Type: Application
    Filed: December 19, 2024
    Publication date: July 17, 2025
    Inventors: Eric J. Alexy, Xiaochun Han, Daniel R. Holycross, Elizabeth M. Horstman, Henry G. Morrison, Justin Y. Su, Marisa Thierheimer
  • Patent number: 12339841
    Abstract: A database management system for performing a graph query based on one or more graph views of a relational-graph database is disclosed. The database management system is configured to determine a plurality of graph views from the relational-graph database based on one or more previous graph queries of the relational-graph database to obtain a plurality of candidate graph views of the relational-graph database. Moreover, the database management system is configured to store a subset of the plurality of candidate graph views of the relational-graph database and perform a graph query of the relational-graph database based on the subset of the plurality of candidate graph views of the relational-graph database. By virtue of the selected subset of the plurality of candidate graph views from the relational-graph database, the database management system can increase the processing speed of graph queries.
    Type: Grant
    Filed: December 8, 2022
    Date of Patent: June 24, 2025
    Assignee: HUAWEI TECHNOLOGIES CO., LTD.
    Inventors: Chao Zhang, Jiaheng Lu, Xiaochun Han, Xinyong Zhang
  • Publication number: 20250127801
    Abstract: The present disclosure relates generally to compounds, of Formula I: Also disclosed are pharmaceutical compositions comprising said compounds and methods of making said compounds. The compounds of the disclosure are useful in treating or preventing human immunodeficiency virus (HIV) infection.
    Type: Application
    Filed: October 10, 2024
    Publication date: April 24, 2025
    Inventors: Megan K. Armstrong, Chienhung Chou, Michael O. Clarke, Ana Z. Gonzalez Buenrostro, Xiaochun Han, Lan Jiang, Jiayao Li, Gregg M. Schwarzwalder, Qiaoyin Wu, Hai Yang
  • Publication number: 20250122219
    Abstract: The present disclosure relates generally to compounds, of Formula I: Also disclosed are pharmaceutical compositions comprising said compounds and methods of making said compounds. The compounds of the disclosure are useful in treating or preventing human immunodeficiency virus (HIV) infection.
    Type: Application
    Filed: October 10, 2024
    Publication date: April 17, 2025
    Inventors: Megan K. Armstrong, Chienhung Chou, Ana Z. Gonzalez Buenrostro, Xiaochun Han, Lan Jiang, Jiayao Li, Gregg M. Schwarzwalder, Qiaoyin Wu, Hai Yang
  • Publication number: 20250120989
    Abstract: The present disclosure relates generally to compounds, of Formula I: Also disclosed are pharmaceutical compositions comprising said compounds and methods of making said compounds. The compounds of the disclosure are useful in treating or preventing human immunodeficiency virus (HIV) infection.
    Type: Application
    Filed: October 10, 2024
    Publication date: April 17, 2025
    Inventors: Megan K. Armstrong, Chienhung Chou, Ana Z. Gonzalez Buenrostro, Xiaochun Han, Lan Jiang, Jiayao Li, Michael L. Mitchell, Gregg M. Schwarzwalder, Aaliyah B. Shodeinde, Murali Subramanian, Qiaoyin Wu, Hai Yang
  • Publication number: 20250115619
    Abstract: Compounds for use in treating or preventing human immunodeficiency virus (HIV) infection are disclosed. The compounds have the following formula (I) including stereoisomers and pharmaceutically acceptable salts thereof, wherein R1, R2, L, W1, W2, X, Y, and Z are as defined herein. Methods associated with the preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
    Type: Application
    Filed: December 20, 2024
    Publication date: April 10, 2025
    Inventors: Hang Chu, Ana Z. Gonzalez Buenrostro, Hongyan Guo, Xiaochun Han, Lan Jiang, Jiayao Li, Michael L. Mitchell, Hyung-Jung Pyun, Scott D. Schroeder, Gregg M. Schwarzwalder, Nathan D. Shapiro, Devleena M. Shivakumar, Qiaoyin Wu, Hong Yang, Jennifer R. Zhang
  • Publication number: 20250115620
    Abstract: The present disclosure relates generally to compounds, of Formula I. Also disclosed are pharmaceutical compositions comprising said compounds and methods of making said compounds. The compounds of the disclosure are useful in treating or preventing human immunodeficiency virus (HIV) infection.
    Type: Application
    Filed: June 3, 2024
    Publication date: April 10, 2025
    Inventors: Hang Chu, Ana Z. Gonzalez Buenrostro, Xiaochun Han, Anna E. Hurtley, Lan Jiang, Jiayao Li, Gregg M. Schwarzwalder, Devleena M. Shivakumar, Matthew J. Von Bargen, Qiaoyin Wu, Hong Yang
  • Patent number: 12227520
    Abstract: Compounds for use in treating or preventing human immunodeficiency virus (HIV) infection are disclosed. The compounds have the following formula (I): including stereoisomers and pharmaceutically acceptable salts thereof, wherein R1, R2, L, W1, W2, X, Y, and Z are as defined herein. Methods associated with the preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
    Type: Grant
    Filed: October 28, 2022
    Date of Patent: February 18, 2025
    Assignee: Gilead Sciences, Inc.
    Inventors: Hang Chu, Ana Z. Gonzalez Buenrostro, Hongyan Guo, Xiaochun Han, Lan Jiang, Jiayao Li, Michael L. Mitchell, Hyung-Jung Pyun, Scott D. Schroeder, Gregg M. Schwarzwalder, Nathan D. Shapiro, Devleena M. Shivakumar, Qiaoyin Wu, Hong Yang, Jennifer R. Zhang
  • Patent number: 12187734
    Abstract: The present disclosure relates generally to certain tricyclic compounds, pharmaceutical compositions comprising said compounds, and methods of making said compounds and pharmaceutical compositions. The compounds of the disclosure are useful in treating or preventing human immunodeficiency virus (HIV) infection.
    Type: Grant
    Filed: December 22, 2023
    Date of Patent: January 7, 2025
    Assignee: Gilead Sciences, Inc.
    Inventors: Hang Chu, Ana Z. Gonzalez Buenrostro, Hongyan Guo, Xiaochun Han, Anna E. Hurtley, Lan Jiang, Jiayao Li, David W. Lin, Michael L. Mitchell, Devan Naduthambi, Gregg M. Schwarzwalder, Suzanne M. Szewczyk, Matthew J. Von Bargen, Qiaoyin Wu, Hong Yang, Jennifer R. Zhang
  • Publication number: 20240300966
    Abstract: The present disclosure relates generally to certain tricyclic compounds, pharmaceutical compositions comprising said compounds, and methods of making said compounds and pharmaceutical compositions. The compounds of the disclosure are useful in treating or preventing human immunodeficiency virus (HIV) infection.
    Type: Application
    Filed: December 22, 2023
    Publication date: September 12, 2024
    Inventors: Hang Chu, Ana Z. Gonzalez Buenrostro, Hongyan Guo, Xiaochun Han, Anna E. Hurtley, Lan Jiang, Jiayao Li, David W. Lin, Michael L. Mitchell, Devan Naduthambi, Gregg M. Schwarzwalder, Suzanne M. Szewczyk, Matthew J. Von Bargen, Qiaoyin Wu, Hong Yang, Jennifer R. Zhang
  • Patent number: 12054496
    Abstract: The present disclosure relates generally to compounds, of Formula I Also disclosed are pharmaceutical compositions comprising said compounds and methods of making said compounds. The compounds of the disclosure are useful in treating or preventing human immunodeficiency virus (HIV) infection.
    Type: Grant
    Filed: June 14, 2023
    Date of Patent: August 6, 2024
    Assignee: Gilead Sciences, Inc.
    Inventors: Hang Chu, Ana Z. Gonzalez Buenrostro, Xiaochun Han, Anna E. Hurtley, Lan Jiang, Jiayao Li, Gregg M. Schwarzwalder, Devleena M. Shivakumar, Matthew J. Von Bargen, Qiaoyin Wu, Hong Yang
  • Patent number: 12024528
    Abstract: The present disclosure relates generally to compounds, of Formula I: Also disclosed are pharmaceutical compositions comprising said compounds and methods of making said compounds. The compounds of the disclosure are useful in treating or preventing human immunodeficiency virus (HIV) infection.
    Type: Grant
    Filed: June 14, 2023
    Date of Patent: July 2, 2024
    Assignee: Gilead Sciences, Inc.
    Inventors: Hang Chu, Ana Z. Gonzalez Buenrostro, Xiaochun Han, Anna E. Hurtley, Lan Jiang, Jiayao Li, Gregg M. Schwarzwalder, Devleena M. Shivakumar, Matthew J. Von Bargen, Qiaoyin Wu, Hong Yang
  • Patent number: 11897892
    Abstract: The present disclosure relates generally to certain tricyclic compounds, pharmaceutical compositions comprising said compounds, and methods of making said compounds and pharmaceutical compositions. The compounds of the disclosure are useful in treating or preventing human immunodeficiency virus (HIV) infection.
    Type: Grant
    Filed: February 3, 2023
    Date of Patent: February 13, 2024
    Assignee: Gilead Sciences, Inc.
    Inventors: Hang Chu, Ana Z. Gonzalez Buenrostro, Hongyan Guo, Xiaochun Han, Anna E. Hurtley, Lan Jiang, Jiayao Li, David W. Lin, Michael L. Mitchell, Devan Naduthambi, Gregg M. Schwarzwalder, Suzanne M. Szewczyk, Matthew J. Von Bargen, Qiaoyin Wu, Hong Yang, Jennifer R. Zhang
  • Publication number: 20230339971
    Abstract: The present disclosure relates generally to compounds, of Formula I Also disclosed are pharmaceutical compositions comprising said compounds and methods of making said compounds. The compounds of the disclosure are useful in treating or preventing human immunodeficiency virus (HIV) infection.
    Type: Application
    Filed: June 14, 2023
    Publication date: October 26, 2023
    Inventors: Hang Chu, Ana Z. Gonzalez Buenrostro, Xiaochun Han, Anna E. Hurtley, Lan Jiang, Jiayao Li, Gregg M. Schwarzwalder, Devleena M. Shivakumar, Matthew J. Von Bargen, Qiaoyin Wu, Hong Yang
  • Publication number: 20230339972
    Abstract: The present disclosure relates generally to compounds, of Formula I: Also disclosed are pharmaceutical compositions comprising said compounds and methods of making said compounds. The compounds of the disclosure are useful in treating or preventing human immunodeficiency virus (HIV) infection.
    Type: Application
    Filed: June 14, 2023
    Publication date: October 26, 2023
    Inventors: Hang Chu, Ana Z. Gonzalez Buenrostro, Xiaochun Han, Anna E. Hurtley, Lan Jiang, Jiayao Li, Gregg M. Schwarzwalder, Devleena M. Shivakumar, Matthew J. Von Bargen, Qiaoyin Wu, Hong Yang
  • Publication number: 20230257389
    Abstract: The present disclosure relates generally to certain tricyclic compounds, pharmaceutical compositions comprising said compounds, and methods of making said compounds and pharmaceutical compositions. The compounds of the disclosure are useful in treating or preventing human immunodeficiency virus (HIV) infection.
    Type: Application
    Filed: February 3, 2023
    Publication date: August 17, 2023
    Inventors: Hang Chu, Ana Z. Gonzalez Buenrostro, Hongyan Guo, Xiaochun Han, Anna E. Hurtley, Lan Jiang, Jiayao Li, David W. Lin, Michael L. Mitchell, Devan Naduthambi, Gregg M. Schwarzwalder, Suzanne M. Szewczyk, Matthew J. Von Bargen, Qiaoyin Wu, Hong Yang, Jennifer R. Zhang
  • Publication number: 20230203061
    Abstract: Compounds for use in treating or preventing human immunodeficiency virus (HIV) infection are disclosed. The compounds have the following formula (I): including stereoisomers and pharmaceutically acceptable salts thereof, wherein R1, R2, L, W1, W2, X, Y, and Z are as defined herein. Methods associated with the preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
    Type: Application
    Filed: October 28, 2022
    Publication date: June 29, 2023
    Inventors: Hang Chu, Ana Z. Gonzalez Buenrostro, Hongyan Guo, Xiaochun Han, Lan Jiang, Jiayao Li, Michael L. Mitchell, Hyung-Jung Pyun, Scott D. Schroeder, Gregg M. Schwarzwalder, Nathan D. Shapiro, Devleena M. Shivakumar, Qiaoyin Wu, Hong Yang, Jennifer R. Zhang
  • Publication number: 20230126509
    Abstract: A database management system for performing a graph query based on one or more graph views of a relational-graph database is disclosed. The database management system is configured to determine a plurality of graph views of the relational-graph database based on one or more previous graph queries of the relational-graph database to obtain a plurality of candidate graph views of the relational-graph database. Moreover, the database management system is configured to store a subset of the plurality of candidate graph views of the relational-graph database and perform a graph query of the relational-graph database based on the subset of the plurality of candidate graph views of the relational-graph database. By means of the selected subset of the plurality of candidate graph views of the relational-graph database, the database management system advantageously allows increasing the processing speed of graph queries.
    Type: Application
    Filed: December 8, 2022
    Publication date: April 27, 2023
    Inventors: Chao ZHANG, Jiaheng LU, Xiaochun HAN, Xinyong ZHANG
  • Patent number: 11613546
    Abstract: The present disclosure relates generally to certain tricyclic compounds, pharmaceutical compositions comprising said compounds, and methods of making said compounds and pharmaceutical compositions. The compounds of the disclosure are useful in treating or preventing human immunodeficiency virus (HIV) infection.
    Type: Grant
    Filed: January 18, 2022
    Date of Patent: March 28, 2023
    Assignee: Gilead Sciences, Inc.
    Inventors: Hang Chu, Ana Z. Gonzalez Buenrostro, Hongyan Guo, Xiaochun Han, Anna E. Hurtley, Lan Jiang, Jiayao Li, David W. Lin, Michael L. Mitchell, Devan Naduthambi, Gregg M. Schwarzwälder, Suzanne M. Szewczyk, Matthew J. Von Bargen, Qiaoyin Wu, Hong Yang, Jennifer R. Zhang
  • Publication number: 20230027019
    Abstract: Compounds for use in treating or preventing human immunodeficiency virus (HIV) infection are disclosed. The compounds have the following formula (I): including stereoisomers and pharmaceutically acceptable salts thereof, wherein R1, R2, L, W1, W2, X, Y, and Z are as defined herein. Methods associated with the preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
    Type: Application
    Filed: June 29, 2021
    Publication date: January 26, 2023
    Inventors: Hang Chu, Ana Z. Gonzalez Buenrostro, Hongyan Guo, Xiaochun Han, Lan Jiang, Jiayao Li, Michael L. Mitchell, Hyung-Jung Pyun, Scott D. Schroeder, Gregg M. Schwarzwalder, Nathan D. Shapiro, Devleena M. Shivakumar, Qiaoyin Wu, Hong Yang, Jennifer R. Zhang