Abstract: Compositions and methods are disclosed for preventing or reducing frizzy appearance of keratin fibers, including hair, and reducing the amount of fly-away strands of hair, particularly in humid conditions, by forming a coating on hair that is resistant to water vapors from the air or surrounding environment. The compositions comprise a combination of a hydrophobic particulate material comprising a hydrophobically surface-modified aluminum oxide and one or more hydrophobic film formers in a cosmetically acceptable vehicle.

Abstract: Compositions and methods are disclosed for preventing or reducing frizzy appearance of keratin fibers, including hair, and reducing the amount of fly-away strands of hair, particularly in humid conditions, by forming a coating on hair that is resistant to water vapors from the air or surrounding environment. The compositions comprise a combination of a hydrophobic particulate material comprising a hydrophobically surface-modified oxide and one or more hydrophobic film formers in a cosmetically acceptable vehicle.

Abstract: Compositions and methods are disclosed for preventing or reducing frizzy appearance of keratin fibers, including hair, and reducing the amount of fly-away strands of hair, particularly in humid conditions, by forming a coating on hair that is resistant to water vapors from the air or surrounding environment. The compositions comprise a combination of a hydrophobic particulate material comprising a hydrophobically surface-modified aluminum oxide and one or more hydrophobic film formers in a cosmetically acceptable vehicle.

Abstract: Compositions and methods are disclosed for preventing or reducing frizzy appearance of keratin fibers, including hair, and reducing the amount of fly-away strands of hair, particularly in humid conditions, by forming a coating on hair that is resistant to water vapors from the air or surrounding environment. The compositions comprise a combination of a hydrophobic particulate material comprising a hydrophobically surface-modified aluminum oxide and one or more hydrophobic film formers in a cosmetically acceptable vehicle.

Abstract: Topical compositions and methods of use to treat symptoms of reduced skin elasticity are provided comprising desthiobiotin and certain desthiobiotin analogues. These compounds are effective in stimulating LOXL-1 activity and can thus increase elastin remodeling and improve appearance of fine lines, wrinkles, skin sagging and other symptoms of reduced elastin function.

Abstract: Topical compositions and methods of use to treat symptoms of reduced skin elasticity are provided comprising extracts of a. Derris scandens Benth. plant. These compositions are effective in stimulating LOXL-1, activity, inhibiting calcineurin activity, and stimulating glycosaminoglycan synthesis in skin cells and can thus reduce age-related skin damage and improve appearance of fine lines, wrinkles, skin sagging and other symptoms of skin aging and/or skin damage.

Abstract: Cosmetic compositions comprising non-natural, non-proteogenic amino acids and methods of using such compositions to impart antiaging benefits to the skin are disclosed. The non-natural, non-proteogenic amino acids are believed to have modulatory activity against one or more biochemical pathways implicated in skin aging, and in particular, are enhancers of LOXL-1.

Abstract: Compositions and methods are disclosed for preventing or reducing frizzy appearance of keratin fibers, including hair, and reducing the amount of fly-away strands of hair, particularly in humid conditions, by forming a coating on hair that is resistant to water vapors from the air or surrounding environment. The compositions comprise a combination of a hydrophobic particulate material comprising a hydrophobically surface-modified aluminum oxide and one or more hydrophobic film formers in a cosmetically acceptable vehicle.

Abstract: Compositions and methods are disclosed for preventing or reducing frizzy appearance of keratin fibers, including hair, and reducing the amount of fly-away strands of hair, particularly in humid conditions, by forming a coating on hair that is resistant to water vapors from the air or surrounding environment. The compositions comprise a combination of a hydrophobic particulate material comprising a hydrophobically surface-modified oxide and one or more hydrophobic film formers in a cosmetically acceptable vehicle.

Abstract: Topical compositions and methods of use to treat symptoms of reduced skin elasticity are provided comprising desthiobiotin and certain desthiobiotin analogues. These compounds are effective in stimulating LOXL-1 activity and can thus increase elastin remodeling and improve appearance of fine lines, wrinkles, skin sagging and other symptoms of reduced elastin function.

Abstract: Cosmetic compositions comprising non-natural, non-proteogenic amino acids and methods of using such compositions to impart antiaging benefits to the skin are disclosed. The non-natural, non-proteogenic amino acids are believed to have modulatory activity against one or more biochemical pathways implicated in skin aging, and in particular, are enhancers of LOXL-1.

Abstract: The present invention provides a water-based composition comprising a non-emulsifying crosslinked silicone elastomer in an amount effective to decrease the amount of sebum on the hair or scalp. The water-based compositions of the present invention are in non-emulsion form. More preferably, the water-based compositions of the present invention have a suspending agent in an amount effective to suspend the crosslinked silicone elastomer within the water-based composition. The present invention also provides to a method of method for absorbing and/or removing sebum and/or styling product residue from the hair or scalp. The method comprises the step of applying the water-based composition to the hair and/or scalp. Preferably, the water-based hair composition is distributed through the hair and/or scalp, e.g., by using a comb or brush.

Abstract: The present invention provides a water-based composition comprising a non-emulsifying crosslinked silicone elastomer in an amount effective to decrease the amount of sebum on the hair or scalp. The water-based compositions of the present invention are in non-emulsion form. More preferably, the water-based compositions of the present invention have a suspending agent in an amount effective to suspend the crosslinked silicone elastomer within the water-based composition. The present invention also provides to a method of method for absorbing and/or removing sebum and/or styling product residue from the hair or scalp. The method comprises the step of applying the water-based composition to the hair and/or scalp. Preferably, the water-based hair composition is distributed through the hair and/or scalp, e.g., by using a comb or brush.

Abstract: There are disclosed non-foaming cleaning compositions, and non-foaming cleaning and conditioning compositions for the hair. The compositions have at least one non-ionic surfactant and, optionally, at least one conditioning ingredient. Preferably, the compositions have a cosmetically acceptable vehicle. There are also disclosed methods for cleaning hair, cleaning and conditioning hair, and protecting color-treated hair that include topically applying the compositions of the present invention.

Abstract: The present invention provides a water-based composition comprising a non-emulsifying crosslinked silicone elastomer in an amount effective to decrease the amount of sebum on the hair or scalp. The water-based compositions of the present invention are in non-emulsion form. More preferably, the water-based compositions of the present invention have a suspending agent in an amount effective to suspend the crosslinked silicone elastomer within the water-based composition.

Abstract: There are disclosed non-foaming cleaning compositions, and non-foaming cleaning and conditioning compositions for the hair. The compositions have at least one non-ionic surfactant and, optionally, at least one conditioning ingredient. Preferably, the compositions have a cosmetically acceptable vehicle. There are also disclosed methods for cleaning hair, cleaning and conditioning hair, and protecting color-treated hair that include topically applying the compositions of the present invention.

Abstract: The present invention provides a novel hair composition, method and system for preventing color loss from dyed hair. The method of decreasing color loss from dyed hair includes a composition having a halogenated compound in an amount effective to decrease such color loss.

Abstract: The subject invention relates to methods for promoting hair growth in mammals comprising topical application of dyphylline or a pharmaceutically-acceptable salt thereof. The subject invention further involves topical compositions comprising dyphylline.

Abstract: The subject invention relates to methods of isolating, culturing and propagating epithelial matrix cells by removing/isolating the bulb region of a hair follicle directly above the dermal papilla, incubating the bulb in a pre-coated culture dish containing Chang medium supplemented with 10% fetal bovine serum, replacing the Chang medium with keratinocyte growth medium after 3-4 days, propagating the cells to the next passage after adding the keratinocyte growth medium and passing the pure epithelial matrix cells again to obtain a third passage of cells. The epithelial matrix cells may be passed for up to six passages, and are useful for screening potential hair growth actives.

Abstract: The present invention relates to an isolated human hair specific keratin gene or fragment thereof, comprising a DNA sequence selected from the group consisting of SEQ ID NO:11; and a DNA sequence comprising DNA sequences SEQ ID NO:6, SEQ ID NO:7, SEQ ID NO:8, SEQ ID NO:9 and SEQ ID NO:10. The present invention also relates to a method for detecting the level of hair specific keratin in a biological sample. The present invention further relates to a method of identifying hair growth regulating compounds and compositions comprising: a) treating a subject with a compound or composition of interest; b) isolating a sample of hair from the subject; and c) using a DNA sequence, or fragment thereof, which encodes hair specific keratin as a marker in a biological assay to detect an increase in the production of hair specific keratin in the hair sample.