Abstract: Provided is engineered microorganisms expressing acetoacetyl-CoA reductase variants and a method for improving the yield of PHA. Compared with the wild-type acetoacetyl-CoA reductase represented by SEQ ID NO. 31, the variant has one or more of the following mutations: (1) mutation of valine at position 141 to isoleucine or leucine; (2) mutation of methionine at position 12 to threonine, serine, alanine, leucine, lysine or isoleucine; (3) mutation of isoleucine at position 194 to valine, leucine or methionine; (4) mutation of glutamic acid at position 42 to lysine, glutamine, leucine, aspartic acid, proline, threonine, asparagine, or histidine; and (5) mutation of phenylalanine at position 55 to valine, alanine or isoleucine. The variants and their coding genes can promote the synthesis and accumulation of PHA by the strain and increase the yield of PHA.

Abstract: Medical devices, plug-ins, systems, and methods for CPR quality feedback are disclosed. The medical devices can calculate peripheral circulation relevant parameters based on measured signals containing at least partial hemodynamic characteristics. Amplitude and area characteristics included in the peripheral circulation relevant parameters can further be determined for providing feedback and control relating to CPR quality during the compression process. Also, compression interruption during CPR can be evaluated based on a pulse waveform generated from the measured signals.

Abstract: The method for improving measurement accuracy of a measurement system includes: emitting, by a light-emitting unit, at least one light signal to penetrate a human tissue; receiving, by a photoelectric conversion unit, the at least one light signal emitted by the light-emitting unit after penetrating the human tissue, and converting the at least one light signal into an electrical signal; converting, by a analog-to-digital conversion unit, the electrical signal into a digital signal; optimizing, by a signal-to-noise ratio optimization module, a signal-to-noise ratio of the digital signal by establishing at least one of a plurality of logic strategies; adjusting, by the driving adjustment unit, an magnitude of a driving current of the light-emitting unit base on the adjustment coefficient; and performing, by an algorithm processing unit, a physiological parameter conversion and calculation based on the digital signal processed by the at least one logic strategy.

Abstract: A finger clip type oximetry device adaptive to thick and thin fingers comprises a housing, an upper finger pad, a lower finger pad, a light emitting device and a receiver provided and a rotating mechanism. Wall surfaces of the upper and lower finger pads enclose an accommodating cavity. An opening is formed in one end of the accommodating cavity. An arc-shaped first contact surface is provided in an area of the lower finger pad in the accommodating cavity in contact with the pulp of the finger, and an arc-shaped second contact surface is provided in an area of the upper finger pad in the accommodating cavity in contact with the finger back. A first concave surface and second concave surfaces are provided along a transverse direction of the finger. The bending degree of the first concave surface is greater than that of the second concave surfaces.

Abstract: An ultrasonic medical monitoring device may include: at least one ultrasonic probe that scans a test subject to acquire an echo signal; a blood pressure measuring device that measures a blood pressure parameter of a peripheral artery of the test subject; a processor configured to receive the echo signal and process the echo signal to obtain a blood flow parameter, and to calculate a myocardial mechanic parameter that represents a synchronous coupling of a circulatory system of left ventricle-aorta-peripheral arteries circulation according to the blood flow parameter and the blood pressure parameter; and a display device that is coupled to the processor and displays the myocardial mechanic parameter.

Abstract: A monitoring system comprises an ultrasonic imaging, an electrocardiograph monitoring module, a data processing module, and an output module. The ultrasonic imaging module is used for obtaining an echocardiogram of heart; the data processing module serves to receive the echocardiogram and obtaining, according to the echocardiogram, mechanical motion identifiers of atriums and ventricles; the data processing module outputs in real-time the mechanical motion identifiers for atriums and ventricles, together with electrocardiogram information, to the output module in a comparative manner.

Abstract: An ultrasonic medical monitoring device may include: at least one ultrasonic probe that scans a test subject to acquire an echo signal; a blood pressure measuring device that measures a blood pressure parameter of a peripheral artery of the test subject; a processor configured to receive the echo signal and process the echo signal to obtain a blood flow parameter, and to calculate a myocardial mechanic parameter that represents a synchronous coupling of a circulatory system of left ventricle-aorta-peripheral arteries circulation according to the blood flow parameter and the blood pressure parameter; and a display device that is coupled to the processor and displays the myocardial mechanic parameter.

Abstract: An ultrasonic medical monitoring device may include: at least one ultrasonic probe attached to a body surface of a subject to scan the body surface and acquire an echo signal; a blood pressure measuring module to measure a blood pressure parameter of the subject; a processing module to receive the echo signal and process the echo signal into a blood flow parameter, the processing module being further configured to calculate a myocardial mechanic parameter according to the blood flow parameter and the blood pressure parameter; and a display module coupled to the processing module to display the blood pressure parameter, the blood flow parameter, and the myocardial mechanic parameter. The present device and method acquire the blood pressure parameter and the blood flow parameter using ultrasound and a blood pressure synchronous detection technique, and the myocardial mechanics parameters such as the systolic maximum elastance are calculated by a computer.

Abstract: This disclosure relates to methods, devices and systems for real-time recognition of restoration of spontaneous circulation (ROSC) in cardio-pulmonary resuscitation (CPR) process. Recognition mechanisms in both time domain and frequency domain are provided for the ROSC recognition, where the time-domain recognition logic may detect the ROSC by recognizing envelope features of sampled signals in the time domain, and the frequency-domain recognition logic may detect the ROSC by recognizing spectral peaks at different frequency points continuously or significant variations of amplitude of spectral peaks in the frequency spectrum.

Abstract: Medical devices, plug-ins, systems, and methods for CPR quality feedback are disclosed. The medical devices can calculate peripheral circulation relevant parameters based on measured signals containing at least partial hemodynamic characteristics. Amplitude and area characteristics included in the peripheral circulation relevant parameters can further be determined for providing feedback and control relating to CPR quality during the compression process. Also, compression interruption during CPR can be evaluated based on a pulse waveform generated from the measured signals.

Abstract: Medical devices, plug-ins, systems, and methods for CPR quality feedback are disclosed. The medical devices can calculate peripheral circulation relevant parameters based on measured signals containing at least partial hemodynamic characteristics. Amplitude and area characteristics included in the peripheral circulation relevant parameters can further be determined for providing feedback and control relating to CPR quality during the compression process. Also, compression interruption during CPR can be evaluated based on a pulse waveform generated from the measured signals.

Abstract: This disclosure relates to methods, devices and systems for real-time recognition of restoration of spontaneous circulation (ROSC) in the cardio-pulmonary resuscitation (CPR) process. Recognition mechanisms in both time domain and frequency domain are provided for the ROSC recognition, where the time-domain recognition logic may detect the ROSC by recognizing envelope features of sampled signals in the time domain, and the frequency-domain recognition logic may detect the ROSC by recognizing spectral peaks at different frequency points continuously or significant variations of amplitude of spectral peaks in the frequency spectrum.

Abstract: A monitoring system comprises an ultrasonic imaging, an electrocardiograph monitoring module, a data processing module, and an output module. The ultrasonic imaging module is used for obtaining an echocardiogram of heart; the data processing module serves to receive the echocardiogram and obtaining, according to the echocardiogram, mechanical motion identifiers of atriums and ventricles; the data processing module outputs in real-time the mechanical motion identifiers for atriums and ventricles, together with electrocardiogram information, to the output module in a comparative manner.

Abstract: Medical devices, plug-ins, systems, and methods for CPR quality feedback are disclosed. The medical devices can calculate peripheral circulation relevant parameters based on measured signals containing at least partial hemodynamic characteristics. Amplitude and area characteristics included in the peripheral circulation relevant parameters can further be determined for providing feedback and control relating to CPR quality during the compression process. Also, compression interruption during CPR can be evaluated based on a pulse waveform generated from the measured signals.

Abstract: Medical devices, plug-ins, systems, and methods for CPR quality feedback are disclosed. The medical devices can calculate peripheral circulation relevant parameters based on measured signals containing at least partial hemodynamic characteristics. Amplitude and area characteristics included in the peripheral circulation relevant parameters can further be determined for providing feedback and control relating to CPR quality during the compression process. Also, compression interruption during CPR can be evaluated based on a pulse waveform generated from the measured signals.

Abstract: An ultrasonic medical monitoring device may include: at least one ultrasonic probe attached to a body surface of a subject to scan the body surface and acquire an echo signal; a blood pressure measuring module to measure a blood pressure parameter of the subject; a processing module to receive the echo signal and process the echo signal into a blood flow parameter, the processing module being further configured to calculate a myocardial mechanic parameter according to the blood flow parameter and the blood pressure parameter; and a display module coupled to the processing module to display the blood pressure parameter, the blood flow parameter, and the myocardial mechanic parameter. The present device and method acquire the blood pressure parameter and the blood flow parameter using ultrasound and a blood pressure synchronous detection technique, and the myocardial mechanics parameters such as the systolic maximum elastance are calculated by a computer.

Abstract: This disclosure relates to methods, devices and systems for real-time recognition of restoration of spontaneous circulation (ROSC) in the cardio-pulmonary resuscitation (CPR) process. Recognition mechanisms in both time domain and frequency domain are provided for the ROSC recognition, where the time-domain recognition logic may detect the ROSC by recognizing envelope features of sampled signals in the time domain, and the frequency-domain recognition logic may detect the ROSC by recognizing spectral peaks at different frequency points continuously or significant variations of amplitude of spectral peaks in the frequency spectrum.

Abstract: Medical devices, plug-ins, systems, and methods for CPR quality feedback are disclosed. The medical devices can calculate peripheral circulation relevant parameters based on measured signals containing at least partial hemodynamic characteristics. Amplitude and area characteristics included in the peripheral circulation relevant parameters can further be determined for providing feedback and control relating to CPR quality during the compression process. Also, compression interruption during CPR can be evaluated based on a pulse waveform generated from the measured signals.