Patents by Inventor Xiaodan Fu

Xiaodan Fu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compound Having Antitumor Activity And Use Thereof
    Publication number: 20240336593
    Abstract: The present disclosure provides a compound having a novel structure as a PRMT5 inhibitor, a method for preparing the compound, and use thereof in the treatment of a disease mediated by a PRMT5 inhibitor. Experiments have shown that these compounds have a strong inhibitory effect on PRMT5, and can be used as promising candidate compounds for treatment of diseases mediated by PRMT5 inhibitors. In addition, a specific synthetic method is developed in the present disclosure, which has a simple process and convenient operation, and is beneficial to industrial mass production and application.
    Type: Application
    Filed: September 3, 2021
    Publication date: October 10, 2024
    Inventors: Qun Dang, Hanyu Yang, Pan Li, Chunhua Jiang, Zhou Yin, Jianbin Ma, Xiaodan Fu, Xin Cai
  • CLASS OF HETEROAROMATIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF
    Publication number: 20240150346
    Abstract: A compound, as represented by formula I, as a TLR7 agonist, a method for preparing the compound, and the use of the compound in treating diseases mediated by the TLR7 agonist are provided. Studies on the activity of a human-derived receptor, a TLR7 agonist, show that compounds have a strong agonistic effect on the human-derived receptor, TLR7, and can be used as a foreground compound for treating diseases mediated by the TLR7 agonist.
    Type: Application
    Filed: January 27, 2022
    Publication date: May 9, 2024
    Inventors: Yunlong SONG, Chen ZHANG, Fang GAO, Weimin LIU, Qun DANG, Pan LI, Zhou YIN, Xin CAI, Xiaodan FU, Jianbin MA
  • Indenoquinolone compound, preparation method and use thereof
    Patent number: 9181193
    Abstract: An indenoquinolone compounds of Formula (A) is disclosed, wherein the definition of each group is described in the description. These compounds may specifically inhibit topoisomerase I, and they have good activities against many kinds of human tumor cells, such as lung cancer, colon cancer, breast cancer, liver cancer and the like. They can be used in the manufacture of antitumor drugs. The method for preparing the compound of formula (A), and pharmaceutical compositions containing such compounds and the use in the manufacture of antitumor drugs are also disclosed.
    Type: Grant
    Filed: May 17, 2011
    Date of Patent: November 10, 2015
    Assignee: Second Military Medical University, PLA
    Inventors: Yunlong Song, Xiaodan Fu, Yunpeng Qi, Yves G. Pommier
  • INDENOQUINOLONE COMPOUND, PREPARATION METHOD AND USE THEREOF
    Publication number: 20130102598
    Abstract: An indenoquinolone compounds of Formula (A) is disclosed, wherein the definition of each group is described in the description. These compounds may specifically inhibit topoisomerase I, and they have good activities against many kinds of human tumor cells, such as lung cancer, colon cancer, breast cancer, liver cancer and the like. They can be used in the manufacture of antitumor drugs. The method for preparing the compound of formula (A), and pharmaceutical compositions containing such compounds and the use in the manufacture of antitumor drugs are also disclosed.
    Type: Application
    Filed: May 17, 2011
    Publication date: April 25, 2013
    Applicant: SECOND MILITARY MEDICAL UNIVERSITY, PLA
    Inventors: Yunlong Song, Xiaodan Fu, Yunpeng Qi