Patents by Inventor Xiaodan Yu

Xiaodan Yu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR THE MICROBIAL PRODUCTION OF SPECIFIC NATURAL CAPSAICINOIDS
    Publication number: 20210317485
    Abstract: The present invention relates to the production of capsaicinoid compounds including Capsaicin and Nonivamide via microbial fermentation.
    Type: Application
    Filed: July 19, 2017
    Publication date: October 14, 2021
    Inventors: Hui Chen, Xiaodan Yu, LanLan Zhou, Hongxue Wang, Min Wang
  • CONTROLLABLE PROTEIN DEGRADATION VIA ENGINEERING DEGRADATION TAG VARIANTS IN CORYNEBACTERIUM HOST CELLS
    Publication number: 20210277405
    Abstract: The present invention relates to the creation of a control system within a host cell to limit or eliminate degradation of key specified products at certain times during fermentation and to redirect the metabolic flux of the cell toward higher production of same key specified products.
    Type: Application
    Filed: March 18, 2021
    Publication date: September 9, 2021
    Applicants: Conagen Inc., Sumitomo Chemical Co., Ltd.
    Inventors: Ilya Tikh, Sonya Clarkson, Brendon Dusel, Jacob Edward Vick, Xiaodan Yu, Bryan Salas-Santiago
  • Biosynthetic production of steviol glycosides and processes therefore
    Patent number: 11098315
    Abstract: The present invention relates to the production of steviol glycoside rebaudiosides D4, WB1 and WB2 and the production of rebaudioside M from Reb D4.
    Type: Grant
    Filed: August 30, 2018
    Date of Patent: August 24, 2021
    Assignee: Conagen Inc.
    Inventors: Guohong Mao, Jacob Edward Vick, Michael Batten, Yang Luo, Yilin Wu, Beihua Zhang, David Byun, Xiaodan Yu
  • BIOSYNTHETIC PRODUCTION OF STEVIOL GLYCOSIDES REBAUDIOSIDE J AND REBAUDIOSIDE N
    Publication number: 20210189448
    Abstract: The present disclosure relates to the production of steviol glycosides rebaudioside J and rebaudioside N through the use of rebaudioside A as a substrate and a biosynthetic pathway involving various 1,2 RhaT-rhamnosyltransferases.
    Type: Application
    Filed: December 2, 2020
    Publication date: June 24, 2021
    Applicant: Conagen Inc.
    Inventors: Guohong Mao, Michael Batten, Phillip Hunt, Oliver (Xiaodan) Yu
  • Biosynthesis of eriodictyol from engineered microbes
    Patent number: 10975403
    Abstract: The present invention relates to the production of eriodictyol via bioconversion.
    Type: Grant
    Filed: July 11, 2018
    Date of Patent: April 13, 2021
    Assignee: Conagen Inc.
    Inventors: Rui Zhou, Xiaodan Yu, Steven Chen
  • Non-caloric sweetener
    Patent number: 10941174
    Abstract: Disclosed is a steviol glycoside referred to as rebaudioside D3. Rebaudioside D3 has five ?-D-glucosyl units connected to the aglycone steviol. Also disclosed are methods for producing rebaudioside D3, a UDP-glycosyltransferase fusion enzyme, and methods for producing rebaudioside D and rebaudioside E.
    Type: Grant
    Filed: April 10, 2020
    Date of Patent: March 9, 2021
    Assignee: Conagen Inc.
    Inventors: Guohong Mao, Venkata Sai Prakash Chaturvedula, Xiaodan Yu
  • BIOSYNTHETIC PRODUCTION OF STEVIOL GLYCOSIDES AND PROCESSES THEREFORE
    Publication number: 20210002685
    Abstract: The present invention relates to the production of steviol glycoside rebaudiosides D4, WB1 and WB2 and the production of rebaudioside M from Reb D4.
    Type: Application
    Filed: June 18, 2020
    Publication date: January 7, 2021
    Applicant: Conagen Inc.
    Inventors: Guohong Mao, Jacob Edward Vick, Michael Batten, David Byun, Yang Luo, Yilin Wu, Beihua Zhang, Xiaodan Yu
  • Biosynthetic production of steviol glycosides rebaudioside J and rebaudioside N
    Patent number: 10883130
    Abstract: The present disclosure relates to the production of steviol glycosides rebaudioside J and rebaudioside N through the use of rebaudioside A as a substrate and a biosynthetic pathway involving various 1,2 RhaT-rhamnosyltransferases.
    Type: Grant
    Filed: November 8, 2019
    Date of Patent: January 5, 2021
    Assignee: Conagen Inc.
    Inventors: Guohong Mao, Michael Batten, Phillip Hunt, Oliver (Xiaodan) Yu
  • NON-CALORIC SWEETENER
    Publication number: 20200361978
    Abstract: Disclosed is a steviol glycoside referred to as rebaudioside D3. Rebaudioside D3 has five ?-D-glucosyl units connected to the aglycone steviol. Also disclosed are methods for producing rebaudioside D3, a UDP-glycosyltransferase fusion enzyme, and methods for producing rebaudioside D and rebaudioside E.
    Type: Application
    Filed: April 10, 2020
    Publication date: November 19, 2020
    Applicant: Conagen Inc.
    Inventors: Guohong Mao, Venkata Sai Prakash Chaturvedula, Xiaodan Yu
  • NON-CALORIC SWEETENERS AND METHODS FOR SYNTHESIZING
    Publication number: 20200339621
    Abstract: Disclosed are steviol glycosides referred to as rebaudioside V and rebaudioside W. Also disclosed are methods for producing rebaudioside M (Reb M), rebausoside G (Reb G), rebaudioside KA (Reb KA), rebaudioside V (Reb V) and rebaudioside (Reb W).
    Type: Application
    Filed: January 28, 2020
    Publication date: October 29, 2020
    Applicant: Conagen Inc.
    Inventors: Guohong Mao, Xiaodan Yu
  • NON-CALORIC SWEETENERS AND METHODS FOR SYNTHESIZING
    Publication number: 20200331952
    Abstract: Disclosed are steviol glycosides referred to as rebaudioside V and rebaudioside W. Also disclosed are methods for producing rebaudioside M (Reb M), rebausoside G (Reb G), rebaudioside KA (Reb KA), rebaudioside V (Reb V) and rebaudioside (Reb W).
    Type: Application
    Filed: February 24, 2020
    Publication date: October 22, 2020
    Applicant: Conagen Inc.
    Inventors: Guohong Mao, Xiaodan Yu
  • Non-caloric sweeteners and methods for synthesizing
    Patent number: 10800803
    Abstract: Disclosed are steviol glycosides referred to as rebaudioside V and rebaudioside W. Also disclosed are methods for producing rebaudioside M (Reb M), rebausoside G (Reb G), rebaudioside KA (Reb KA), rebaudioside V (Reb V) and rebaudioside (Reb W).
    Type: Grant
    Filed: November 2, 2017
    Date of Patent: October 13, 2020
    Assignee: Conagen Inc.
    Inventors: Guohong Mao, Xiaodan Yu
  • Method for the microbial production of 8-methyl nonanoic acid
    Patent number: 10793881
    Abstract: The present disclosure relates to the production of 8-methyl nonanoic acid and medium chain branched fatty acids, e.g., via microbial fermentation.
    Type: Grant
    Filed: June 18, 2019
    Date of Patent: October 6, 2020
    Assignee: Conagen Inc.
    Inventors: Hui Chen, Xiaodan Yu
  • Non-caloric sweeteners and methods for synthesizing
    Patent number: 10774103
    Abstract: Disclosed are steviol glycosides referred to as rebaudioside V and rebaudioside W. Also disclosed are methods for producing rebaudioside M (Reb M), rebausoside G (Reb G), rebaudioside KA (Reb KA), rebaudioside V (Reb V) and rebaudioside (Reb W).
    Type: Grant
    Filed: November 2, 2017
    Date of Patent: September 15, 2020
    Assignee: Conagen Inc.
    Inventors: Guohong Mao, Xiaodan Yu
  • Enzymes and methods for styrene synthesis
    Patent number: 10752921
    Abstract: The subject technology generally relates to biosynthesis of styrene. Certain embodiments of the subject technology is based, in part, on the recognition that phenylalanine can be converted to styrene by a two-step pathway of deamination and de-carboxylation, with trans-cinnamic acid (tCA) as the intermediate. Two types of enzymes are directly involved in this process, phenylalanine ammonia lyase (PAL), which converts phenylalanine to tCA, and cinnamic acid decarboxylase, which coverts tCA to styrene. Host cells expressing these two types of enzymes can be cultured in bioreactor to produce styrene from renewable substrates such as glucose.
    Type: Grant
    Filed: September 15, 2017
    Date of Patent: August 25, 2020
    Assignee: Phytogene, Inc.
    Inventors: Mohammad Wadud Bhuiya, Hui Chen, Xianpeng Cai, Jixiang Han, Xiaodan Yu
  • Production of non-caloric sweeteners using engineered whole-cell catalysts
    Patent number: 10752928
    Abstract: Disclosed are whole-cell catalysts, methods of making the whole-cell catalysts, and methods of using the whole-cell catalysts to produce steviol glycosides.
    Type: Grant
    Filed: April 14, 2016
    Date of Patent: August 25, 2020
    Assignee: Conagen Inc.
    Inventors: Guohong Mao, Jacob Edward Vick, Shi-Yan Li, Xiaodan Yu
  • Biosynthetic production of steviol glycosides and processes therefore
    Patent number: 10724062
    Abstract: The present invention relates to the production of steviol glycoside rebaudiosides D4, WB1 and WB2 and the production of rebaudioside M from Reb D4.
    Type: Grant
    Filed: April 12, 2019
    Date of Patent: July 28, 2020
    Assignee: Conagen Inc.
    Inventors: Guohong Mao, Jacob Edward Vick, Michael Batten, David Byun, Yang Luo, Yilin Wu, Beihua Zhang, Xiaodan Yu
  • Non-caloric sweetener
    Patent number: 10654881
    Abstract: Disclosed is a steviol glycoside referred to as rebaudioside D2. Rebaudioside D2 has five ?-D-glucosyl units connected to the aglycone steviol. Also disclosed are methods for producing rebaudioside D2, a UDP-glycosyltransferase fusion enzyme, and methods for producing rebaudioside D and rebaudioside E.
    Type: Grant
    Filed: September 12, 2017
    Date of Patent: May 19, 2020
    Assignee: Conagen Inc.
    Inventors: Guohong Mao, Venkata Sai Prakash Chaturvedula, Xiaodan Yu
  • Methods of making capsinoids by biosynthetic processes
    Patent number: 10655150
    Abstract: Provided herein are methods of making capsinoids including providing a capsiate synthase in a mixture or cellular system, feeding 8-methyl-6-nonenoyl-CoA, 6E-8-methylnonenoic acid or 8-methylnonanoic acid into the mixture or cellular system, feeding vanillyl alcohol into the mixture or cellular system, and collecting capsinoids from the mixture or cellular system.
    Type: Grant
    Filed: January 6, 2017
    Date of Patent: May 19, 2020
    Assignee: Conagen Inc.
    Inventors: Hui Chen, Xiaodan Yu
  • BIOSYNTHETIC PRODUCTION OF STEVIOL GLYCOSIDE REBAUDIOSIDE D4 FROM REBAUDIOSIDE E
    Publication number: 20200102588
    Abstract: The present invention relates, in some aspects, to the production of steviol glycoside rebaudioside D4 through the use of rebaudioside E. In some aspects, the invention relates to mutant CP1 enzymes, mutant HV1 enzymes as well as host cells and methods utilizing such enzymes, such as to produce rebaudioside D4.
    Type: Application
    Filed: September 6, 2019
    Publication date: April 2, 2020
    Applicant: Conagen Inc.
    Inventors: Guohong Mao, Jacob Edward Vick, Michael Batten, Yang Luo, Yilin Wu, Xiaodan Yu