Patents by Inventor Xiaodan Yu

Xiaodan Yu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for the microbial production of specific natural capsaicinoids
    Patent number: 11459591
    Abstract: The present invention relates to the production of capsaicinoid compounds including Capsaicin and Nonivamide via microbial fermentation.
    Type: Grant
    Filed: July 19, 2017
    Date of Patent: October 4, 2022
    Assignee: Conagen Inc.
    Inventors: Hui Chen, Xiaodan Yu, LanLan Zhou, Hongxue Wang, Min Wang
  • Non-caloric sweeteners and methods for synthesizing
    Patent number: 11453692
    Abstract: Disclosed are steviol glycosides referred to as rebaudioside V and rebaudioside W. Also disclosed are methods for producing rebaudioside M (Reb M), rebausoside G (Reb G), rebaudioside KA (Reb KA), rebaudioside V (Reb V) and rebaudioside (Reb W).
    Type: Grant
    Filed: February 24, 2020
    Date of Patent: September 27, 2022
    Assignee: Conagen Inc.
    Inventors: Guohong Mao, Xiaodan Yu
  • Biosynthetic production of steviol glycoside rebaudioside I via variant enzymes
    Patent number: 11447808
    Abstract: The present invention relates, at least in part, to the production of steviol glycoside rebaudioside I through the use of variant UGT enzymes having activity to transfer a glucosyl group from UDP-glucose to rebaudioside A to produce rebaudioside I.
    Type: Grant
    Filed: July 9, 2019
    Date of Patent: September 20, 2022
    Assignee: Conagen Inc.
    Inventors: Guohong Mao, Michael Batten, Xiaodan Yu
  • Biosynthetic production of steviol glycosides rebaudioside J and rebaudioside N
    Patent number: 11441165
    Abstract: The present disclosure relates to the production of steviol glycosides rebaudioside J and rebaudioside N through the use of rebaudioside A as a substrate and a biosynthetic pathway involving various 1,2 RhaT-rhamnosyltransferases.
    Type: Grant
    Filed: December 2, 2020
    Date of Patent: September 13, 2022
    Assignee: Conagen Inc.
    Inventors: Guohong Mao, Michael Batten, Phillip Hunt, Oliver (Xiaodan) Yu
  • BIOSYNTHETIC PRODUCTION OF STEVIOL GLYCOSIDE REBAUDIOSIDE D4 FROM REBAUDIOSIDE E
    Publication number: 20220282297
    Abstract: The present invention relates, in some aspects, to the production of steviol glycoside rebaudioside D4 through the use of rebaudioside E. In some aspects, the invention relates to mutant CP1 enzymes, mutant HV1 enzymes as well as host cells and methods utilizing such enzymes, such as to produce rebaudioside D4.
    Type: Application
    Filed: March 17, 2022
    Publication date: September 8, 2022
    Applicant: Conagen Inc.
    Inventors: Guohong Mao, Jacob Edward Vick, Michael Batten, Yang Luo, Yilin Wu, Xiaodan Yu
  • BIOSYNTHETIC PRODUCTION OF STEVIOL GLYCOSIDE REBAUDIOSIDE I VIA VARIANT ENZYMES
    Publication number: 20220205007
    Abstract: The present invention relates, at least in part, to the production of steviol glycoside rebaudioside I through the use of variant UGT enzymes having activity to transfer a glucosyl group from UDP-glucose to rebaudioside A to produce rebaudioside I.
    Type: Application
    Filed: January 7, 2022
    Publication date: June 30, 2022
    Applicant: Conagen Inc.
    Inventors: Guohong Mao, Michael Batten, Xiaodan Yu
  • OPTIMAL LOAD CURTAILMENT CALCULATING METHOD BASED ON LAGRANGE MULTIPLIER AND APPLICATION THEREOF
    Publication number: 20220188477
    Abstract: The present invention relates to an optimal load curtailment calculating method based on Lagrange multiplier and an application thereof in power system reliability assessment, wherein the calculating method comprises the following steps: inputting all system states to be analyzed for reliability assessment and establishing corresponding optimal load curtailment models; classifying the optimal load curtailment models according to Lagrange multiplier to obtain several sets; and solving the optimal load curtailment models in each set by using Lagrange multipliers to obtain an optimal load curtailment corresponding to the system state. The core of the present invention is to establish Lagrange-multiplier-based linear functions between the optimal load curtailment and the system states, and the iterative optimization processes of the traditional optimal load curtailment calculating method are substituted with the simple matrix multiplications.
    Type: Application
    Filed: August 30, 2019
    Publication date: June 16, 2022
    Inventors: Kai HOU, Zeyu LIU, Hongjie JIA, Dan WANG, Yunfei MU, Xiaodan YU, Lewei ZHU
  • NON-CALORIC SWEETENERS AND METHODS FOR SYNTHESIZING
    Publication number: 20220162248
    Abstract: Disclosed are steviol glycosides referred to as rebaudioside V and rebaudioside W. Also disclosed are methods for producing rebaudioside M (Reb M), rebausoside G (Reb G), rebaudioside KA (Reb KA), rebaudioside V (Reb V) and rebaudioside (Reb W).
    Type: Application
    Filed: November 29, 2021
    Publication date: May 26, 2022
    Applicant: Conagen Inc.
    Inventors: Guohong Mao, Xiaodan Yu
  • Biosynthetic production of steviol glycoside rebaudioside D4 from rebaudioside E
    Patent number: 11306340
    Abstract: The present invention relates, in some aspects, to the production of steviol glycoside rebaudioside D4 through the use of rebaudioside E. In some aspects, the invention relates to mutant CP1 enzymes, mutant HV1 enzymes as well as host cells and methods utilizing such enzymes, such as to produce rebaudioside D4.
    Type: Grant
    Filed: September 6, 2019
    Date of Patent: April 19, 2022
    Assignee: Conagen Inc.
    Inventors: Guohong Mao, Jacob Edward Vick, Michael Batten, Yang Luo, Yilin Wu, Xiaodan Yu
  • BIOSYNTHESIS PRODUCTION OF STEVIOL GLYCOSIDES AND PROCESSES THEREFORE
    Publication number: 20220042060
    Abstract: The present invention relates to the production of steviol glycoside rebaudiosides D4, WB1 and WB2 and the production of rebaudioside M from Reb D4.
    Type: Application
    Filed: July 28, 2021
    Publication date: February 10, 2022
    Applicant: Conagen Inc.
    Inventors: Guohong Mao, Jacob Edward Vick, Michael Batten, Yang Luo, Yilin Wu, Beihua Zhang, David Byun, Xiaodan Yu
  • Non-caloric sweeteners and methods for synthesizing
    Patent number: 11186604
    Abstract: Disclosed are steviol glycosides referred to as rebaudioside V and rebaudioside W. Also disclosed are methods for producing rebaudioside M (Reb M), rebausoside G (Reb G), rebaudioside KA (Reb KA), rebaudioside V (Reb V) and rebaudioside (Reb W).
    Type: Grant
    Filed: January 28, 2020
    Date of Patent: November 30, 2021
    Assignee: Conagen Inc.
    Inventors: Guohong Mao, Xiaodan Yu
  • METHOD FOR THE MICROBIAL PRODUCTION OF SPECIFIC NATURAL CAPSAICINOIDS
    Publication number: 20210317485
    Abstract: The present invention relates to the production of capsaicinoid compounds including Capsaicin and Nonivamide via microbial fermentation.
    Type: Application
    Filed: July 19, 2017
    Publication date: October 14, 2021
    Inventors: Hui Chen, Xiaodan Yu, LanLan Zhou, Hongxue Wang, Min Wang
  • CONTROLLABLE PROTEIN DEGRADATION VIA ENGINEERING DEGRADATION TAG VARIANTS IN CORYNEBACTERIUM HOST CELLS
    Publication number: 20210277405
    Abstract: The present invention relates to the creation of a control system within a host cell to limit or eliminate degradation of key specified products at certain times during fermentation and to redirect the metabolic flux of the cell toward higher production of same key specified products.
    Type: Application
    Filed: March 18, 2021
    Publication date: September 9, 2021
    Applicants: Conagen Inc., Sumitomo Chemical Co., Ltd.
    Inventors: Ilya Tikh, Sonya Clarkson, Brendon Dusel, Jacob Edward Vick, Xiaodan Yu, Bryan Salas-Santiago
  • Biosynthetic production of steviol glycosides and processes therefore
    Patent number: 11098315
    Abstract: The present invention relates to the production of steviol glycoside rebaudiosides D4, WB1 and WB2 and the production of rebaudioside M from Reb D4.
    Type: Grant
    Filed: August 30, 2018
    Date of Patent: August 24, 2021
    Assignee: Conagen Inc.
    Inventors: Guohong Mao, Jacob Edward Vick, Michael Batten, Yang Luo, Yilin Wu, Beihua Zhang, David Byun, Xiaodan Yu
  • BIOSYNTHETIC PRODUCTION OF STEVIOL GLYCOSIDES REBAUDIOSIDE J AND REBAUDIOSIDE N
    Publication number: 20210189448
    Abstract: The present disclosure relates to the production of steviol glycosides rebaudioside J and rebaudioside N through the use of rebaudioside A as a substrate and a biosynthetic pathway involving various 1,2 RhaT-rhamnosyltransferases.
    Type: Application
    Filed: December 2, 2020
    Publication date: June 24, 2021
    Applicant: Conagen Inc.
    Inventors: Guohong Mao, Michael Batten, Phillip Hunt, Oliver (Xiaodan) Yu
  • Biosynthesis of eriodictyol from engineered microbes
    Patent number: 10975403
    Abstract: The present invention relates to the production of eriodictyol via bioconversion.
    Type: Grant
    Filed: July 11, 2018
    Date of Patent: April 13, 2021
    Assignee: Conagen Inc.
    Inventors: Rui Zhou, Xiaodan Yu, Steven Chen
  • Non-caloric sweetener
    Patent number: 10941174
    Abstract: Disclosed is a steviol glycoside referred to as rebaudioside D3. Rebaudioside D3 has five ?-D-glucosyl units connected to the aglycone steviol. Also disclosed are methods for producing rebaudioside D3, a UDP-glycosyltransferase fusion enzyme, and methods for producing rebaudioside D and rebaudioside E.
    Type: Grant
    Filed: April 10, 2020
    Date of Patent: March 9, 2021
    Assignee: Conagen Inc.
    Inventors: Guohong Mao, Venkata Sai Prakash Chaturvedula, Xiaodan Yu
  • BIOSYNTHETIC PRODUCTION OF STEVIOL GLYCOSIDES AND PROCESSES THEREFORE
    Publication number: 20210002685
    Abstract: The present invention relates to the production of steviol glycoside rebaudiosides D4, WB1 and WB2 and the production of rebaudioside M from Reb D4.
    Type: Application
    Filed: June 18, 2020
    Publication date: January 7, 2021
    Applicant: Conagen Inc.
    Inventors: Guohong Mao, Jacob Edward Vick, Michael Batten, David Byun, Yang Luo, Yilin Wu, Beihua Zhang, Xiaodan Yu
  • Biosynthetic production of steviol glycosides rebaudioside J and rebaudioside N
    Patent number: 10883130
    Abstract: The present disclosure relates to the production of steviol glycosides rebaudioside J and rebaudioside N through the use of rebaudioside A as a substrate and a biosynthetic pathway involving various 1,2 RhaT-rhamnosyltransferases.
    Type: Grant
    Filed: November 8, 2019
    Date of Patent: January 5, 2021
    Assignee: Conagen Inc.
    Inventors: Guohong Mao, Michael Batten, Phillip Hunt, Oliver (Xiaodan) Yu
  • NON-CALORIC SWEETENER
    Publication number: 20200361978
    Abstract: Disclosed is a steviol glycoside referred to as rebaudioside D3. Rebaudioside D3 has five ?-D-glucosyl units connected to the aglycone steviol. Also disclosed are methods for producing rebaudioside D3, a UDP-glycosyltransferase fusion enzyme, and methods for producing rebaudioside D and rebaudioside E.
    Type: Application
    Filed: April 10, 2020
    Publication date: November 19, 2020
    Applicant: Conagen Inc.
    Inventors: Guohong Mao, Venkata Sai Prakash Chaturvedula, Xiaodan Yu