Patents by Inventor Xiaode Lu

Xiaode Lu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Three dimensional structure of a ZAP tyrosine protein kinase fragment and modeling methods
    Patent number: 6251620
    Abstract: The invention relates to human ZAP-70, and in particular, to the region of ZAP-70 containing the tandem Src homology-2 (“SH2”) domains, to crystalline forms thereof, liganded or unliganded, which are particularly useful for the determination of the three-dimensional structure of the protein. The three dimensional structure of the tandem SH2 region of ZAP provides information useful for the design of pharmaceutical compositions which inhibit the biological function of ZAP and other members of the ZAP family of SH2 domain-containing proteins, particularly those biological functions mediated by molecular interactions involving one or both SH2 domains.
    Type: Grant
    Filed: November 18, 1997
    Date of Patent: June 26, 2001
    Assignee: Ariad Pharmaceuticals, Inc.
    Inventors: Marcos H. Hatada, Xiaode Lu, Ellen R. Laird, Jennifer L. Karas, Mark J. Zoller, Dennis A. Holt