Patents by Inventor Xiaodong Ma

Xiaodong Ma has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12591786
    Abstract: An intelligent ammunition co-evolution task assignment method is disclosed. The method includes the following steps. A chromosome gene encoding of genetic algorithm for ammunition assignment scheme of multi-platform interception operation is performed. A fitness of chromosome individual function in a genetic population is calculated according to a threat degree of an intercepting target in the ammunition assignment scheme and an interception probability of the intercepting target by different ammunition launching platforms. A probability ranking sequence of effective interception of the intercepting target by different ammunition launching platforms is obtained, and a genetic algorithm selection operation is performed on the chromosome individuals according to probability values of effective interception in descending order of priority.
    Type: Grant
    Filed: July 18, 2022
    Date of Patent: March 31, 2026
    Assignee: HARBIN INSTITUTE OF TECHNOLOGY
    Inventors: Yuliang Bai, Ningyu Wang, Yongzhi Shan, Long Zhang, Liangchen Xu, Yuan Li, Xiaodong Ma
  • Patent number: 12582691
    Abstract: Clinically validated methods of administering Yunnan Baiyao or Xingnaojing can improve postoperative recovery and long-term clinical prognosis of patients with moderate-to-severe traumatic brain injury (TBI) and emergency craniotomy. Both medicinal methods are useful for minimizing or inhibiting the adverse impacts of secondary injury, oxidative damage and neuroinflammation associated with TBI, spinal cord injury, craniotomy/craniectomy, cerebral hemostasis and hemorrhage, coagulopathy, stroke, neural injury and neuroinflammation, and for promoting the long-term functional recovery and well-being of the patients with the afore-mentioned diseases.
    Type: Grant
    Filed: July 12, 2022
    Date of Patent: March 24, 2026
    Assignee: Lotus Biotech.com LLC
    Inventors: Guoqiang Xing, Xiaodong Ma
  • Patent number: 12582425
    Abstract: In some examples, a catheter includes an elongated body and an expandable member at a distal portion of the elongated body and defining at least part of a distal tip of the catheter. The expandable member is formed from materials that enable a distal tip of the catheter to be radiopaque without the addition of a separate radiopaque marker (e.g., a solid metal ring of radiopaque material separate from and connected to the elongated body) at the distal tip of the catheter.
    Type: Grant
    Filed: December 3, 2020
    Date of Patent: March 24, 2026
    Assignee: Covidien LP
    Inventors: Eric Mintz, Ujwal Jalgaonkar, Syamala Rani Pulugurtha, Athanasios Touris, Kevin V. Nguyen, Xiaodong Ma, Edwin Wang
  • Publication number: 20260002933
    Abstract: A protein detection method and a detection device as well as use are provided. The protein detection method includes: fixing a probe type graphic encoding chip coupled with a specific capture antibody in the detection device, and meanwhile respectively sealing SAPE and a detection antibody in the detection device; and when in detection, performing detection and analysis based on an enzyme linked immunosorbent assay (ELISA) principle through the probe-type graphic encoding chip after the detection antibody and the SAPE are respectively dissolved, so as to obtain protein quantitative analysis results.
    Type: Application
    Filed: June 5, 2024
    Publication date: January 1, 2026
    Applicant: SUZHOU INSTITUTE OF NANO-TECH AND NANO-BIONICS (SINANO) , CHINESE ACADEMY OF SCIENCES
    Inventors: Jiong LI, Yiran HE, Kefeng PU, Chaoxu LUO, Xiaodong MA, Min JIANG
  • Patent number: 12268617
    Abstract: Methods for forming an expandable tubular body having a plurality of braided filaments including a first filament including platinum or platinum alloy and a second filament including cobalt-chromium alloy. The methods include applying a first phosphorylcholine material directly on the platinum or platinum alloy of the first filament and applying a silane material on the second filament followed by a second phosphorylcholine material on the silane material on the second filament. The first and second phosphorylcholine materials each define a thickness of less than 100 nanometers.
    Type: Grant
    Filed: February 19, 2024
    Date of Patent: April 8, 2025
    Assignee: Covidien LP
    Inventors: Xiaodong Ma, Min-Shyan Sheu, Lincoln Eramo, John Wainwright, Junwei Li
  • Publication number: 20240206893
    Abstract: In some examples, a medical aspiration system includes a vacuum source; a vacuum tube coupled to the vacuum source; a vent tube; and a device configured to convert a constant suction force from the vacuum source into a periodic suction force, the device including a housing configured to receive a portion of the vacuum tube and a portion of the vent tube; a first plunger; a second plunger; and a rotatable cam configured to cause the first plunger to periodically compress the vacuum tube and to cause the second plunger to periodically compress the vent tube.
    Type: Application
    Filed: March 7, 2024
    Publication date: June 27, 2024
    Inventors: Peter Skujins, Brad L. Jackson, Xiaodong Ma
  • Publication number: 20240189121
    Abstract: Methods for forming an expandable tubular body having a plurality of braided filaments including a first filament including platinum or platinum alloy and a second filament including cobalt-chromium alloy. The methods include applying a first phosphorylcholine material directly on the platinum or platinum alloy of the first filament and applying a silane material on the second filament followed by a second phosphorylcholine material on the silane material on the second filament. The first and second phosphorylcholine materials each define a thickness of less than 100 nanometers.
    Type: Application
    Filed: February 19, 2024
    Publication date: June 13, 2024
    Inventors: Xiaodong Ma, Min-Shyan Sheu, Lincoln Eramo, John Wainwright, Junwei Li
  • Patent number: 11982725
    Abstract: Magnetic resonance images with improved image quality consistent with those obtained using parallel radio frequency (“RF”) transmission (“pTx”) techniques are generated from data acquired using single transmission hardware (e.g., single channel RF transmission). A deep-learning framework is used to train a deep neural network to convert images obtained with single transmission into pTx-like images. The pTx-like images have reduced signal variations and dropouts that may otherwise be attributable to B1+ inhomogeneities.
    Type: Grant
    Filed: May 2, 2022
    Date of Patent: May 14, 2024
    Assignee: REGENTS OF THE UNIVERSITY OF MINNESOTA
    Inventors: Xiaoping Wu, Xiaodong Ma, Kamil Ugurbil
  • Patent number: 11957365
    Abstract: In some examples, a medical aspiration system includes a vacuum source; a vacuum tube coupled to the vacuum source; a vent tube; and a device configured to convert a constant suction force from the vacuum source into a periodic suction force, the device including a housing configured to receive a portion of the vacuum tube and a portion of the vent tube; a first plunger; a second plunger; and a rotatable cam configured to cause the first plunger to periodically compress the vacuum tube and to cause the second plunger to periodically compress the vent tube.
    Type: Grant
    Filed: November 20, 2020
    Date of Patent: April 16, 2024
    Assignee: Covidien LP
    Inventors: Peter Skujins, Brad L. Jackson, Xiaodong Ma
  • Patent number: 11903850
    Abstract: Methods for forming an expandable tubular body having a plurality of braided filaments including a first filament including platinum or platinum alloy and a second filament including cobalt-chromium alloy. The methods include applying a first phosphorylcholine material directly on the platinum or platinum alloy of the first filament and applying a silane material on the second filament followed by a second phosphorylcholine material on the silane material on the second filament. The first and second phosphorylcholine materials each define a thickness of less than 100 nanometers.
    Type: Grant
    Filed: August 9, 2022
    Date of Patent: February 20, 2024
    Assignee: Covidien LP
    Inventors: Xiaodong Ma, Min-Shyan Sheu, Lincoln Eramo, John Wainwright, Junwei Li
  • Publication number: 20230036800
    Abstract: Methods for forming an expandable tubular body having a plurality of braided filaments including a first filament including platinum or platinum alloy and a second filament including cobalt-chromium alloy. The methods include applying a first phosphorylcholine material directly on the platinum or platinum alloy of the first filament and applying a silane material on the second filament followed by a second phosphorylcholine material on the silane material on the second filament. The first and second phosphorylcholine materials each define a thickness of less than 100 nanometers.
    Type: Application
    Filed: August 9, 2022
    Publication date: February 2, 2023
    Inventors: Xiaodong Ma, Min-Shyan Sheu, Lincoln Eramo, John Wainwright, Junwei Li
  • Publication number: 20230024831
    Abstract: Clinically validated methods of administering Yunnan Baiyao or Xingnaojing can improve postoperative recovery and long-term clinical prognosis of patients with moderate-to-severe traumatic brain injury (TBI) and emergency craniotomy. Both medicinal methods are useful for minimizing or inhibiting the adverse impacts of secondary injury, oxidative damage and neuroinflammation associated with TBI, spinal cord injury, craniotomy/craniectomy, cerebral hemostasis and hemorrhage, coagulopathy, stroke, neural injury and neuroinflammation, and for promoting the long-term functional recovery and well-being of the patients with the afore-mentioned diseases.
    Type: Application
    Filed: July 12, 2022
    Publication date: January 26, 2023
    Applicant: Lotus Biotech.com LLC
    Inventors: Guoqiang Xing, Xiaodong Ma
  • Patent number: 11535601
    Abstract: The invention relates to the field of pharmaceutical synthesis, in particular to a preparation method of (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-ol derivatives and their intermediates. The preparation method is carried out starting from compound Formula A1. In the preparation of (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-ol derivatives, the chirality was constructed by enzymatic method, and the products were prepared with high optical purity. The preparation method can be used to produce the key intermediates of (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-ol of darunavir commercially, which is a very economical route suitable for industrial production.
    Type: Grant
    Filed: July 30, 2018
    Date of Patent: December 27, 2022
    Inventors: Zhaobo Gao, Jianhua Chen, Zhidong Wan, Dawei He, Zengle Zhou, Xiaodong Ma, Wei Xiang, Jingxin Lin, Yijiang Mei
  • Publication number: 20220374722
    Abstract: An intelligent ammunition co-evolution task assignment method is disclosed. The method includes the following steps. A chromosome gene encoding of genetic algorithm for ammunition assignment scheme of multi-platform interception operation is performed. A fitness of chromosome individual function in a genetic population is calculated according to a threat degree of an intercepting target in the ammunition assignment scheme and an interception probability of the intercepting target by different ammunition launching platforms. A probability ranking sequence of effective interception of the intercepting target by different ammunition launching platforms is obtained, and a genetic algorithm selection operation is performed on the chromosome individuals according to probability values of effective interception in descending order of priority.
    Type: Application
    Filed: July 18, 2022
    Publication date: November 24, 2022
    Applicant: HARBIN INSTITUTE OF TECHNOLOGY
    Inventors: Yuliang BAI, Ningyu WANG, Yongzhi SHAN, Long ZHANG, Liangchen XU, Yuan LI, Xiaodong MA
  • Patent number: D1065202
    Type: Grant
    Filed: October 25, 2023
    Date of Patent: March 4, 2025
    Inventors: Xiaodong Ma, Xude Zhou, Xianzhang Wu
  • Patent number: D1068765
    Type: Grant
    Filed: December 2, 2022
    Date of Patent: April 1, 2025
    Assignee: Jian Zhongrui Electronics Co., Ltd.
    Inventors: Xiaodong Ma, Xude Zhou, Jianghua Yang, Xianzhang Wu
  • Patent number: D1080633
    Type: Grant
    Filed: June 25, 2024
    Date of Patent: June 24, 2025
    Inventors: Xiaodong Ma, Xude Zhou, Xianzhang Wu
  • Patent number: D1105080
    Type: Grant
    Filed: December 9, 2024
    Date of Patent: December 9, 2025
    Inventors: Xiaodong Ma, Xude Zhou, Xianzhang Wu
  • Patent number: D1110314
    Type: Grant
    Filed: August 29, 2024
    Date of Patent: January 27, 2026
    Inventors: Xiaodong Ma, Xude Zhou, Xianzhang Wu
  • Patent number: D1129378
    Type: Grant
    Filed: June 26, 2025
    Date of Patent: June 9, 2026
    Inventors: Xiaodong Ma, Xude Zhou, Xianzhang Wu