Abstract: The present invention discloses a gene mining method and system based on transcriptome and DNA methylome. The gene mining method comprises: acquiring samples; performing transcriptome sequencing on the samples and analyzing data obtained by the sequencing to obtain differentially expressed genes; performing DNA methylation sequencing on the samples and analyzing data obtained by the sequencing to obtain differentially methylated genes; performing gene function enrichment on the obtained differentially expressed genes and differentially methylated genes to obtain a molecular protein-protein interaction (PPI) network; and performing gene clustering with the molecular PPI network to identify target genes. The present invention solves the problems that it takes time and effort to mine core genes of existing transcriptome and methylome and the result is not accurate enough. The present invention mines target genes by organically integrating originally isolated transcriptome data and DNA methylome data.

Abstract: A display substrate and a display apparatus. The display substrate includes a base substrate and a drive circuit layer provided on the base substrate. The base substrate includes a display region (100) and a non-display region (200), the drive circuit layer includes a pixel drive circuit (PE) located in the display region, a gate drive circuit located in the non-display region and at least one initial power supply line extending at least partially in a first direction (D1). The gate drive circuit is configured to provide a drive signal to the pixel drive circuit, and the initial power supply line is configured to provide an initial signal to the pixel drive circuit. An orthographic projection of at least one of the at least one initial power supply line on the base substrate is at least partially overlapped with an orthographic projection of the gate drive circuit on the base substrate.

Abstract: A display panel includes a display area (110) and a non-display area (120), wherein the non-display area (120) includes a first non-display area; a signal line layer (200) is arranged on a side of a base substrate (100); a touch layer (300) is arranged on a side of the signal line layer (200) away from the base substrate (100), and includes a plurality of touch lines (310), wherein, in at least part of the touch lines (310) in the first non-display area, a first touch line (311) and a second touch line (312) belonging to the same touch line (310) respectively have a first center line O1 and a second center line O2, and in a direction perpendicular to the extension of the touch line (310), the first center line O1 and the second center line O2 are not aligned.

Abstract: The invention provides a novel process, novel process steps and novel intermediates useful in the synthesis of pharmaceutically active compounds, especially KRAS G12C inhibitors. The present invention provides a direct enantioselective chemical manufacturing method of making Compound A, or a pharmaceutically acceptable hydrate or solvent thereof: (I). The invention provides a process for preparing Intermediate B6* comprising reacting Intermediate B4* with Intermediate B5* in an atroposelective coupling reaction, using a chiral catalyst.

Abstract: Disclosed is a saturation enhancement method, the method comprising: performing color space conversion on an input image to obtain color data of color conversion; performing saturation expansion on the color data of the color conversion to obtain expanded color data; and performing Gamma preprocessing on the expanded color data to obtain processed color data. Also disclosed are a saturation enhancement device and a computer readable storage medium.

Abstract: A method of configuring an on-die termination circuit in each non-volatile memory die of a plurality of non-volatile memory dice that have one or more pads coupled in common, includes determining, by each of the non-volatile memory dice whether that non-volatile memory die is a target or a non-target for a memory operation; setting, by each of the non-volatile memory die that determines it is a target, a first on-die termination configuration value; setting, by each of the non-volatile memory die that determines it is a non-target, a second on-die termination configuration value; configuring, by each of the target non-volatile memory die, its corresponding on-die termination circuit to provide a first impedance based, at least in part, on the first on-die termination configuration value; and concurrently with the configuring by each target non-volatile memory die, configuring, by each non-target non-volatile memory die, its corresponding on-die termination circuit to provide a second impedance based, at least

Abstract: A display apparatus includes a display panel, a mirror switching screen, a first photosensitive sensor, a first flexible circuit board and a driver board. The mirror switching screen is disposed on a light-exit side of the display panel. The first photosensitive sensor is configured to sense a light intensity of ambient light at a side of the mirror switching screen away from the display panel. The first flexible circuit board includes a bonding portion, a component portion and a wiring portion. The bonding portion is electrically connected to the mirror switching screen. The first photosensitive sensor is disposed on a side of the component portion proximate to the mirror switching portion. The wiring portion has lines electrically connected to the first photosensitive sensor and bonding pads of the bonding portion. The driver board is electrically connected to the wiring portion of the first flexible circuit board.

Abstract: The stator assembly of the present application includes a multi-phase winding and a stator core being provided with a stator slot. A branch includes a first coil group, a second coil group and a connecting wire. The first coil group includes N first winding parts and N-1 first variable-layer lines, and the first winding part includes a plurality of coil sets, the coil set includes a first cross-layer unit and a first variable-pitch unit; a span of the first variable-pitch unit is greater than or less than the pole pitch of motor; the first variable-layer line connects two adjacent first winding parts, and a span yl of the first variable-layer line is set as: y?2?yl<y+2; the second variable-layer line connects with two adjacent second winding parts, and a span y2 of the second variable-layer line is set as: y2=y.

Abstract: The present invention relates to the technical field of wastewater treatment, and discloses a bioaugmentation treatment process for lithium battery producing wastewater. The method comprises the following steps: 1) introducing wastewater into a hydrolytic acidification tank, and adding Enterobacter sp. NJUST50 and activated sludge to the hydrolytic acidification tank for hydrolytic acidification treatment; 2) introducing the effluent into an anoxic tank, and adding Enterobacter sp. NJUST50 and anaerobic activated sludge for anoxic treatment; 3) introducing the effluent into an aerobic tank, and adding Enterobacter sp. NJUST50 and aerobic activated sludge for aerobic treatment; 4) introducing the effluent into an anoxic filter tank, and adding Enterobacter sp. NJUST50 and anaerobic activated sludge to the filter tank for treatment; and 5) introducing the effluent into a biological aerated filter tank, and adding a sludge mixture of Enterobacter sp.

Abstract: The present disclosure belongs to the technical fields of nanoscience and fluorescence sensing, and specifically relates to a preparation method of a paper-based sensor for detecting an ammonia gas, and a use of the paper-based sensor. In the present disclosure, Zn(PA)(BPE) is first prepared, and a porous structure on a surface of the Zn(PA)(BPE) is used to adsorb an ammonia gas to improve a reaction sensitivity of the ammonia gas; then a Zn(PA)@CNQD ratiometric fluorescent substance is prepared from Zn(PA)(BPE) and CNQD through embedding, and finally dissolved in ultrapure water (UPW) to obtain a solution; and the solution is added dropwise on a filter paper, and the filter paper is purged with nitrogen, such that the solution is loaded on the filter paper to obtain a ratiometric fluorescent paper-based sensor.

Abstract: According to one aspect of the present disclosure, a memory is provided. The memory may include a row hammer control circuit including a plurality of counters. Each of the plurality of counters may count a number of accesses of one memory row. Each of the plurality of counters may be configured to generate a first count value. The memory may include an adjustment circuit connected with the plurality of counters. The adjustment circuit may reset each of the plurality of counters when each of a plurality of first count values reaches a target threshold. The adjustment circuit may adjust each of the first count values by a same offset value to generate a plurality of second count values. The row hammer control circuit may determine a target memory row according to the plurality of second count values.

Abstract: Implementations of the present disclosure disclose a memory and an operating method thereof, a memory system, and an electronic device. The memory includes a memory cell array and a peripheral circuit coupled with the memory cell array. The peripheral circuit includes: a temperature sensing circuit configured to sense a temperature of the memory and generate a temperature signal based on the sensed temperature; a control logic circuit configured to determine a target refresh period based on the temperature signal and a mapping table, wherein the mapping table includes a plurality of preset temperature signals and a plurality of preset refresh periods in a one-to-one correspondence; and a refresh control circuit configured to adjust a refresh period of a refresh signal to the target refresh period, wherein the refresh signal is configured to indicate performing a refresh operation on the memory cell array.

Abstract: A method for domain name detection, a device and a storage medium are provided. The method includes: matching a to-be-detected domain name with a preset domain name set; in response to the to-be-detected domain name being not in the preset domain name set, calculating an edit distance between at least part of level domain names of the to-be-detected domain name and a preset domain name keyword in a domain name keyword set; in response to an edit distance between a target level domain name and a target preset domain name keyword being smaller than preset distance threshold, acquiring a character pair in which the target level domain name differs from the target preset domain name keyword, and matching with a similar character pair set; and in response to determining the character pair being in the similar character pair set, determining that the to-be-detected domain name has a security risk.

Abstract: Disclosed is a fully immersed energy storage device, which includes a casing and a water pump. An insulation box is mounted inside the casing, and the insulation box is assembled with an assembly plate thereon. A mounting platform is mounted on the assembly plate and assembled with an annular rack. A rotating groove is provided between the mounting platform and the annular rack. Balls are placed in the rotating groove. The mounting platform is assembled with an assembly block, on which a rotating shaft is mounted. One end of the rotating shaft connects to a gear. The other end of the rotating shaft connects to a first assembly rod, to which a second assembly rod is connected. The second assembly rod connects to a fixed block, which is connected to an energy storage box. A motor base is mounted on the casing. A motor is mounted on the motor base.

Abstract: A touch substrate (01) and a touch display device. The touch substrate (01) includes: a base substrate (101); a plurality of first touch electrodes (102) located on the base substrate (101); a plurality of second touch electrodes (103) located on a side, facing away from the base substrate (101), of a layer where the first touch electrodes (102) are located and insulated from the first touch electrodes (102); and a plurality of floating electrodes (104) insulated from the plurality of first touch electrodes (102) and the plurality of second touch electrodes (103), and arranged on the same layer as at least one of the first touch electrodes (102) or the second touch electrodes (103). Each floating electrode (104) has a grid shape, and at least part of the floating electrodes (104) is disconnected at at least part of dots.

Abstract: The present invention provides a capsule endoscope, including: an enclosure; a battery component disposed in an accommodating space enclosed by the enclosure; a circuit control component electrically connected to the battery component and disposed adjacent to the battery component; an image acquisition component electrically connected to the circuit control component; a first thermally conductive element disposed between the battery component and the circuit control component; and a second thermally conductive element in contact with the image acquisition component and the battery component, respectively.

Abstract: A hydro-mechanical series and parallel transmission device and a control method thereof are provided. The device includes an input shaft assembly, a hydraulic transmission assembly, a planetary gear transmission assembly, an intermediate gear transmission assembly, and an output shaft assembly. Switching among a hydraulic transmission mode, a mechanical transmission mode, and a hydro-mechanical composite transmission mode is implemented through combination and engagement/disengagement of clutches and brakes. The hydro-mechanical series transmission is used to expand the speed regulation range of the hydraulic transmission and is combined with the hydraulic transmission to meet the requirements on precision and the speed regulation range. The requirements of low-power and high-power operations are met through combination of the hydro-mechanical series and parallel transmissions. Multiple transmission modes are formed to adapt to the working conditions of startup, operation, and transfer.

Abstract: The present application relates to a silicone oil-based immersion coolant for an electronic component. The silicone oil-based immersion coolant for an electronic component includes a base oil and an additive. The base oil includes a low-viscosity silicone oil. The additive includes a silicone oil diluent and a thermally conductive inorganic filler. The viscosity of the low-viscosity silicone oil is less than or equal to 1000 cSt. The thermally conductive inorganic filler is an insulating filler. Based on the mass of the immersion coolant, a mass percentage content of the base oil is in a range from 70% to 85%, a mass percentage content of the silicone oil diluent is in a range from 10% to 20%, and a mass percentage content of the thermally conductive inorganic filler is in a range from 5% to 10%.

Abstract: Disclosed are a hydraulic control system for boom floating of an excavator and a control method thereof. In the hydraulic circuit, a main pump supplies oil to the boom cylinder through a boom reversing valve, and two working ports of the boom reversing valve are connected to a rod cavity and a rodless cavity of the boom cylinder respectively. A rod cavity floating valve and a rodless cavity floating valve are connected to an oil circuit between the rod cavity of the boom cylinder and the boom reversing valve and an oil circuit between the rodless cavity of the boom cylinder and the boom reversing valve respectively. A pilot oil pump and a handle pilot valve are arranged on the pilot oil circuit, an oil inlet of the handle pilot valve is connected to the pilot oil pump.