Patents by Inventor Xiaodong Zhong

Xiaodong Zhong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250062433
    Abstract: The present application relates to a silicone oil-based immersion coolant for an electronic component. The silicone oil-based immersion coolant for an electronic component includes a base oil and an additive. The base oil includes a low-viscosity silicone oil. The additive includes a silicone oil diluent and a thermally conductive inorganic filler. The viscosity of the low-viscosity silicone oil is less than or equal to 1000 cSt. The thermally conductive inorganic filler is an insulating filler. Based on the mass of the immersion coolant, a mass percentage content of the base oil is in a range from 70% to 85%, a mass percentage content of the silicone oil diluent is in a range from 10% to 20%, and a mass percentage content of the thermally conductive inorganic filler is in a range from 5% to 10%.
    Type: Application
    Filed: November 17, 2023
    Publication date: February 20, 2025
    Applicant: CSG PWR GEN. (GUANGDONG) ENRGY. STR. TCH. CO. LTD
    Inventors: Bangjin LIU, Zhiqiang WANG, Chao DONG, Jin WANG, Yueli ZHOU, Jiasheng WU, Cheng PENG, Min ZHANG, Bin WU, Linwei WANG, Qihua LIN, Xiaodong ZHENG, Zheng WENG, Shaohua ZHAO, Lunsen ZOU, Guobin ZHONG, Fei YU, Jia LUO, Xuan LIU, Kaiqi XU, Chao WANG
  • Patent number: 12196833
    Abstract: Systems and methods for generative adversarial networks (GANs) to remove artifacts from undersampled magnetic resonance (MR) images are described. The process of training the GAN can include providing undersampled 3D MR images to the generator model, providing the generated example and a real example to the discriminator model, applying adversarial loss, L2 loss, and structural similarity index measure loss to the generator model based on a classification output by the discriminator model, and repeating until the generator model has been trained to remove the artifacts from the undersampled 3D MR images. At runtime, the trained generator model of the GAN can be generate artifact-free images or parameter maps from undersampled MRI data of a patient.
    Type: Grant
    Filed: May 19, 2021
    Date of Patent: January 14, 2025
    Assignees: Siemens Healthineers AG, The Regents of the University of California
    Inventors: Peng Hu, Xiaodong Zhong, Chang Gao, Valid Ghodrati
  • Publication number: 20250005715
    Abstract: A method for correcting echo planar imaging artifacts includes correcting at least one echo planar imaging artifact in an image to obtain a correct image. A trained neural network is used to correct the at least one echo planar imaging artifact. The image is obtained through echo planar imaging.
    Type: Application
    Filed: June 30, 2023
    Publication date: January 2, 2025
    Inventors: Catalina Raymond, Benjamin Ellingson, Jingwen Yao, Thorsten Feiweier, Bryan Clifford, Xiaodong Zhong
  • Patent number: 12118728
    Abstract: A computer implemented method of processing a medical image is disclosed. The method includes receiving a medical image comprising a first plurality of pixels each having an initial pixel value. For each of the first plurality of pixels, a filtering operation is applied to the pixel to generate a filtered pixel value for the pixel based on the initial pixel values of pixels that surround the pixel in the medical image. For each of the first plurality of pixels, a comparison of the initial pixel value with the filtered pixel value is performed. The method comprises, for each of the first plurality of pixels, determining, based on the comparison, whether or not to categorize the pixel as an erroneous pixel; and for each of the first plurality of pixels for which it is determined to categorize the pixel as an erroneous pixel, categorizing the pixel as an erroneous pixel.
    Type: Grant
    Filed: January 24, 2022
    Date of Patent: October 15, 2024
    Assignee: Siemens Healthineers AG
    Inventors: Xiaodong Zhong, Vibhas S. Deshpande, Marcel Dominik Nickel, Stephan Kannengiesser
  • Publication number: 20240331225
    Abstract: A method of generating at least one image using a magnetic resonance imaging (MRI) system includes generating, for each contrast of a plurality of contrasts, an image by forming a multi-dimensional data matrix by dividing MRI imaging data for a contrast into a plurality of bins and generating the image based on at least the MRI imaging data and the multi-dimensional data matrix. Each bin of the plurality of bins corresponds to one of a plurality of respiratory motion states.
    Type: Application
    Filed: September 11, 2023
    Publication date: October 3, 2024
    Inventors: Xiaodong Zhong, Marcel Dominik Nickel, Stephan Kannengiesser, Vibhas S. Deshpande
  • Publication number: 20240037815
    Abstract: Systems and methods for recreating images from undersampled MRI image data includes capturing undersampled MRI data and enhancing it with multiple cascading stages, each including a data consistency block in parallel to a convolutional neural network (CNN). The data consistency block adjusts each input image by a sensitivity map and performs hard replacement of acquired lines in k-space into the image. The CNN estimates a regularizer term that attempts to minimize a difference between a true image and the output of the data consistency block. At each stage, the output of CNN and data consistency block are added to create a set of output images that feed into the next stage.
    Type: Application
    Filed: July 26, 2022
    Publication date: February 1, 2024
    Inventors: Vahid Ghodrati, Chang Gao, Peng Hu, Xiaodong Zhong, Jens Wetzl, Jianing Pang
  • Publication number: 20230342993
    Abstract: Systems and methods for recreating images from undersampled magnetic resonance imaging (MRI) image data remove artifacts from the undersampling. Using trained transformer networks, undersampled k-space data can be acquired and the networks can predict additional projected radial MRI k-space data from the undersampled radial MRI k-space data. Images with fewer artifacts can then be generated.
    Type: Application
    Filed: September 23, 2022
    Publication date: October 26, 2023
    Inventors: Chang Gao, John Paul Finn, Xiaodong Zhong
  • Patent number: 11796620
    Abstract: A method for acquiring magnetic resonance imaging data with respiratory motion compensation using one or more motion signals includes acquiring a plurality of gradient-delay-corrected radial readout views of a subject using a free-breathing multi-echo pulse sequence, and sampling a plurality of data points of the gradient-delay-corrected radial readout views to yield a self-gating signal. The self-gating signal is used to determine a plurality of respiratory motion states corresponding to the plurality of gradient-delay-corrected radial readout views. The respiratory motion states are used to correct respiratory motion bias in the gradient-delay-corrected radial readout views, thereby yielding gradient-delay-corrected and motion-compensated multi-echo data. One or more images are reconstructed using the gradient-delay-corrected and motion-compensated multi-echo data.
    Type: Grant
    Filed: October 1, 2021
    Date of Patent: October 24, 2023
    Assignees: Siemens Healthcare GmbH, The Regents of the University of California
    Inventors: Xiaodong Zhong, Holden H. Wu, Vibhas S. Deshpande, Tess Armstrong, Li Pan, Marcel Dominik Nickel, Stephan Kannengiesser
  • Publication number: 20220381861
    Abstract: Systems and methods for generative adversarial networks (GANs) to remove artifacts from undersampled magnetic resonance (MR) images are described. The process of training the GAN can include providing undersampled 3D MR images to the generator model, providing the generated example and a real example to the discriminator model, applying adversarial loss, L2 loss, and structural similarity index measure loss to the generator model based on a classification output by the discriminator model, and repeating until the generator model has been trained to remove the artifacts from the undersampled 3D MR images. At runtime, the trained generator model of the GAN can be generate artifact-free images or parameter maps from undersampled MRI data of a patient.
    Type: Application
    Filed: May 19, 2021
    Publication date: December 1, 2022
    Inventors: Peng Hu, Xiaodong Zhong, Chang Gao, Valid Ghodrati
  • Publication number: 20220365158
    Abstract: A system and method for performing accelerated k-space shift correction calibration scans for non-Cartesian trajectories is provided. The method can include applying an MRI sequence, performing a calibration scan based on the MRI sequence using the non-Cartesian trajectory to acquire k-space shift data, wherein one or more partitions are skipped during the calibration scan, interpolating the skipped one or more partitions using the k-space shift data from adjacent partitions, and calibrating the MRI system using the k-space shift data and the interpolated k-space shift data. In some embodiments, an acceleration factor Acc can be defined and the calibration scan acquires k-space shift data for only one partition in every Acc partitions.
    Type: Application
    Filed: May 17, 2021
    Publication date: November 17, 2022
    Inventors: Xiaodong Zhong, Vibhas S. Deshpande, Marcel Dominik Nickel, Fei Han
  • Patent number: 11480639
    Abstract: A system and method for performing accelerated k-space shift correction calibration scans for non-Cartesian trajectories is provided. The method can include applying an MRI sequence, performing a calibration scan based on the MRI sequence using the non-Cartesian trajectory to acquire k-space shift data, wherein one or more partitions are skipped during the calibration scan, interpolating the skipped one or more partitions using the k-space shift data from adjacent partitions, and calibrating the MRI system using the k-space shift data and the interpolated k-space shift data. In some embodiments, an acceleration factor Acc can be defined and the calibration scan acquires k-space shift data for only one partition in every Acc partitions.
    Type: Grant
    Filed: May 17, 2021
    Date of Patent: October 25, 2022
    Assignee: Siemens Healthcare GmbH
    Inventors: Xiaodong Zhong, Vibhas S. Deshpande, Marcel Dominik Nickel, Fei Han
  • Patent number: 11454687
    Abstract: A method for using a multi-echo magnetic resonance imaging (MRI) simultaneously quantify T1 and fat fraction in an anatomical region of interest includes performing a radial single shot multi-echo acquisition of the anatomical region of interest. The radial single shot multi-echo acquisition comprises applying a preparation pulse to invert longitudinal magnetization of the anatomical region of interest, and acquiring a plurality of radial readouts at different echo times (TE). A magnetization recovery curve is continuously sampled using the plurality of radial readouts to yield a plurality of radial spokes. The radial spokes for each TE are ground together to generate under-sampled k-space data for each TE. The under-sampled k-space data is reconstructed into a plurality of multi-echo images corresponding to the different echo times. One or more fitting algorithms are applied to the multi-echo images to generate a water-only T1 map and a proton density fat fraction (PDFF) measurement.
    Type: Grant
    Filed: April 1, 2020
    Date of Patent: September 27, 2022
    Assignee: Siemens Healthcare GmbH
    Inventors: Mahesh Bharath Keerthivasan, Xiaodong Zhong, Marcel Dominik Nickel, Vibhas S. Deshpande
  • Publication number: 20220245817
    Abstract: A computer implemented method of processing a medical image is disclosed. The method includes receiving a medical image comprising a first plurality of pixels each having an initial pixel value. For each of the first plurality of pixels, a filtering operation is applied to the pixel to generate a filtered pixel value for the pixel based on the initial pixel values of pixels that surround the pixel in the medical image. For each of the first plurality of pixels, a comparison of the initial pixel value with the filtered pixel value is performed. The method comprises, for each of the first plurality of pixels, determining, based on the comparison, whether or not to categorize the pixel as an erroneous pixel; and for each of the first plurality of pixels for which it is determined to categorize the pixel as an erroneous pixel, categorizing the pixel as an erroneous pixel.
    Type: Application
    Filed: January 24, 2022
    Publication date: August 4, 2022
    Inventors: Xiaodong Zhong, Vibhas S. Deshpande, Marcel Dominik Nickel, Stephan Kannengiesser
  • Patent number: 11333734
    Abstract: A method of generating biomarker parameters includes acquiring imaging data depicting a patient using a MRI system. The imaging data is acquired for a plurality of contrasts resulting from application of a pulse on the patient's anatomy. A process is executed to generate a MoCoAve image for each contrast. This process includes dividing the imaging data for the contrast into bins corresponding to one of a plurality of respiratory motion phases, and reconstructing the imaging data in each bin to yield bin images. The process further includes selecting a reference bin image from the bin images, and warping the bin images based on the reference bin image. The warped bin images and the reference bin image are averaged to generate the MoCoAve image for the contrast. One or more biomarker parameter maps are calculated based on the MoCoAve images generated for the contrasts.
    Type: Grant
    Filed: May 7, 2020
    Date of Patent: May 17, 2022
    Assignee: Siemens Healthcare GmbH
    Inventors: Xiaodong Zhong, Vibhas S. Deshpande, Marcel Dominik Nickel, Xiaoming Bi, Stephan Kannengiesser, Berthold Kiefer
  • Patent number: 11327135
    Abstract: A computer-implemented method for using machine learning to suppress fat in acquired MR images includes receiving multi-echo images from an anatomical area of interest acquired using an MRI system. A first subset of the multi-echo images is acquired prior to application of contrast to the anatomical area of interest and a second subset of the multi-echo images is acquired after application of contrast to the anatomical area of interest. Next, data is generated including water images, fat images, and effective R*2 maps from the multi-echo images. The water images, the fat images, and the effective R*2 maps are used to create synthetic fat suppressed images. A neural network is trained to use the multi-echo images as input and the synthetic fat suppressed images as ground truth. A plurality of components of the neural network are saved to allow later deployment of the neural network on a computing system.
    Type: Grant
    Filed: June 30, 2020
    Date of Patent: May 10, 2022
    Assignees: Siemens Healthcare GmbH, Duke University
    Inventors: Xiaodong Zhong, Vibhas S. Deshpande, Mustafa R. Bashir
  • Publication number: 20220128641
    Abstract: A method for acquiring magnetic resonance imaging data with respiratory motion compensation using one or more motion signals includes acquiring a plurality of gradient-delay-corrected radial readout views of a subject using a free-breathing multi-echo pulse sequence, and sampling a plurality of data points of the gradient-delay-corrected radial readout views to yield a self-gating signal. The self-gating signal is used to determine a plurality of respiratory motion states corresponding to the plurality of gradient-delay-corrected radial readout views. The respiratory motion states are used to correct respiratory motion bias in the gradient-delay-corrected radial readout views, thereby yielding gradient-delay-corrected and motion-compensated multi-echo data. One or more images are reconstructed using the gradient-delay-corrected and motion-compensated multi-echo data.
    Type: Application
    Filed: October 1, 2021
    Publication date: April 28, 2022
    Inventors: Xiaodong Zhong, Holden H. Wu, Vibhas S. Deshpande, Tess Armstrong, Li Pan, Marcel Dominik Nickel, Stephan Kannengiesser
  • Patent number: 11175366
    Abstract: A method for acquiring magnetic resonance imaging data with respiratory motion compensation using one or more motion signals includes acquiring a plurality of gradient-delay-corrected radial readout views of a subject using a free-breathing multi-echo pulse sequence, and sampling a plurality of data points of the gradient-delay-corrected radial readout views to yield a self-gating signal. The self-gating signal is used to determine a plurality of respiratory motion states corresponding to the plurality of gradient-delay-corrected radial readout views. The respiratory motion states are used to correct respiratory motion bias in the gradient-delay-corrected radial readout views, thereby yielding gradient-delay-corrected and motion-compensated multi-echo data. One or more images are reconstructed using the gradient-delay-corrected and motion-compensated multi-echo data.
    Type: Grant
    Filed: February 5, 2020
    Date of Patent: November 16, 2021
    Assignees: Siemens Healthcare GmbH, The Regents of the University of California
    Inventors: Xiaodong Zhong, Holden H. Wu, Vibhas S. Deshpande, Tess Armstrong, Li Pan, Marcel Dominik Nickel, Stephan Kannengiesser
  • Publication number: 20210349166
    Abstract: A method of generating biomarker parameters includes acquiring imaging data depicting a patient using a MRI system. The imaging data is acquired for a plurality of contrasts resulting from application of a pulse on the patient's anatomy. A process is executed to generate a MoCoAve image for each contrast. This process includes dividing the imaging data for the contrast into bins corresponding to one of a plurality of respiratory motion phases, and reconstructing the imaging data in each bin to yield bin images. The process further includes selecting a reference bin image from the bin images, and warping the bin images based on the reference bin image. The warped bin images and the reference bin image are averaged to generate the MoCoAve image for the contrast. One or more biomarker parameter maps are calculated based on the MoCoAve images generated for the contrasts.
    Type: Application
    Filed: May 7, 2020
    Publication date: November 11, 2021
    Inventors: Xiaodong Zhong, Vibhas S. Deshpande, Marcel Dominik Nickel, Xiaoming Bi, Stephan Kannengiesser, Berthold Kiefer
  • Publication number: 20210311145
    Abstract: A method for using a multi-echo magnetic resonance imaging (MRI) simultaneously quantify T1 and fat fraction in an anatomical region of interest includes performing a radial single shot multi-echo acquisition of the anatomical region of interest. The radial single shot multi-echo acquisition comprises applying a preparation pulse to invert longitudinal magnetization of the anatomical region of interest, and acquiring a plurality of radial readouts at different echo times (TE). A magnetization recovery curve is continuously sampled using the plurality of radial readouts to yield a plurality of radial spokes. The radial spokes for each TE are ground together to generate under-sampled k-space data for each TE. The under-sampled k-space data is reconstructed into a plurality of multi-echo images corresponding to the different echo times. One or more fitting algorithms are applied to the multi-echo images to generate a water-only T1 map and a proton density fat fraction (PDFF) measurement.
    Type: Application
    Filed: April 1, 2020
    Publication date: October 7, 2021
    Inventors: Mahesh Bharath Keerthivasan, Xiaodong Zhong, Marcel Dominik Nickel, Vibhas S. Deshpande
  • Publication number: 20210302522
    Abstract: A computer-implemented method for using machine learning to suppress fat in acquired MR images includes receiving multi-echo images from an anatomical area of interest acquired using an MRI system. A first subset of the multi-echo images is acquired prior to application of contrast to the anatomical area of interest and a second subset of the multi-echo images is acquired after application of contrast to the anatomical area of interest. Next, data is generated including water images, fat images, and effective R*2 maps from the multi-echo images. The water images, the fat images, and the effective R*2 maps are used to create synthetic fat suppressed images. A neural network is trained to use the multi-echo images as input and the synthetic fat suppressed images as ground truth. A plurality of components of the neural network are saved to allow later deployment of the neural network on a computing system.
    Type: Application
    Filed: June 30, 2020
    Publication date: September 30, 2021
    Inventors: Xiaodong Zhong, Vibhas S. Deshpande, Mustafa R. Bashir