Patents by Inventor Xiaoer XIA

Xiaoer XIA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BRUTON'S TYROSINE KINASE INHIBITOR AND PREPARATION METHOD THEREFOR
    Publication number: 20230348471
    Abstract: A type of Bruton's tyrosine kinase inhibitor, a preparation method therefor, and an application thereof in the field of medicine. The Bruton's tyrosine kinase inhibitor may be used for preventing and/or treating a disease related to Bruton's tyrosine kinase mediation, such as an autoimmune disease, cancer, or an inflammatory disease. Through experimental research, the provided compound has high selectivity with respect to a Bruton's tyrosine kinase target, and can exhibit a uniquely advantageous medicinal effect in an in vivo animal experiment.
    Type: Application
    Filed: June 18, 2021
    Publication date: November 2, 2023
    Inventors: Xin Xu, Jia Chen, Guan Wang, Linli Zhang, Qingyun Jiang, Chenghao Xi, Kang Sun, Xiaojuan Zhang, Chunqiao Chen, Shuai Li, Qiang Li, Liangze Xia, Ying Wang, Xiaoer Xia
  • PD-1/PD-L1 INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF
    Publication number: 20230111910
    Abstract: Provided are a compound as a PD-L1 inhibitor, a preparation method therefor, and use thereof. Further provided is use of the compound or a pharmaceutical composition thereof in the preparation of a medicine, wherein the medicine is used for preventing and treating a PD-L1-related disease.
    Type: Application
    Filed: January 21, 2021
    Publication date: April 13, 2023
    Inventors: Xin XU, Jia CHEN, Liming ZHANG, Xuqin YANG, Maozhi YANG, Xiaojuan ZHANG, Yanxiao XU, Xiaobo ZHOU, Hao YU, Yuyun ZHANG, Ying WANG, Xiaoer XIA
  • JAK KINASE INHIBITOR, PREPARATION METHOD FOR SAME, AND APPLICATIONS THEREOF IN FIELD OF MEDICINE
    Publication number: 20220185816
    Abstract: Related are a JAK kinase inhibitor, a preparation method for same, and applications thereof in the field of medicine, related to the field of medicinal chemistry. Provided is a novel small molecule JAK inhibitor, which has the structure as represented by formula (II). The compound provides improved efficacy and safeness in preventing or treating a JAK-related indication.
    Type: Application
    Filed: March 11, 2020
    Publication date: June 16, 2022
    Applicants: SHANGHAI SYNERGY PHARMACEUTICAL SCIENCES CO., LTD, ZHEJIANG HUAHAI PHARMACEUTICAL CO., LTD.
    Inventors: Xin XU, Jia CHEN, Zhen ZHANG, Guan WANG, Linli ZHANG, Qiang LI, Chenghao XI, Minkai QU, Xiaojuan ZHANG, Chunqiao CHEN, Fan YANG, Xiaoer XIA, Yijin WANG, Yunfei LI, Jian GE
  • Preparation Method for Amide Compound and Application Thereof in Field of Medicine
    Publication number: 20220098178
    Abstract: The present invention relates to a preparation method for an amide compound and an application thereof in the field of medicine. Specifically, provided by the present invention is an amide small molecule compound which is an inhibitor of Zeste gene enhancer homolog 2 (EZH2) and which may be used to prevent and/or treat EZH2-mediated related diseases, comprising tumors, myeloproliferative diseases or autoimmune diseases.
    Type: Application
    Filed: March 24, 2020
    Publication date: March 31, 2022
    Inventors: Xin XU, Jia CHEN, Zhen ZHANG, Liming ZHANG, Qimei WU, Qingyun JIANG, Fengying GUO, Yuyun ZHANG, Hao YU, Ying WANG, Kang SUN, Chengxu ZANG, Chenggang QIN, Xiaobo ZHOU, Xiaojuan ZHANG, Yijin WANG, Xiaoer XIA, Yunfei LI, Jian GE
  • Preparation Method for Amide Compounds and Use Thereof in Medical Field
    Publication number: 20220024941
    Abstract: Provided are a preparation method for amide compounds and use thereof in medical field. Specifically, provided are small molecule amide compounds. Such compounds are inhibitors of enhancer homolog 2 (EZH2) of Zeste gene, and can be used for preventing and/or treating related diseases mediated by EZH2, including tumors, myeloproliferative diseases or autoimmune diseases.
    Type: Application
    Filed: March 24, 2020
    Publication date: January 27, 2022
    Inventors: Xin XU, Jia CHEN, Zhen ZHANG, Liming ZHANG, Qimei WU, Qingyun JIANG, Fengying GUO, Yuyun ZHANG, Hao YU, Xiaojuan ZHANG, Kang SUN, Xiaobo ZHOU, Chengxu ZANG, Yijin WANG, Xiaoer XIA, Yunfei LI, Jian GE
  • Vortioxetine pamoic acid salt and crystal form thereof
    Patent number: 10793536
    Abstract: The present application provides a vortioxetine pamoic acid salt, which includes a crystal form, a solvate or an amorphous substance of the vortioxetine pamoic acid salt. The present application provides a preparation method and use of the vortioxetine pamoic acid salt and the crystal form thereof. The vortioxetine pamoic acid salt prepared in the present application prolongs the residence time of the vortioxetine in vivo, achieving a slow release of the vortioxetine in vivo, and is suitable for preparing a long-acting dosage form.
    Type: Grant
    Filed: March 28, 2017
    Date of Patent: October 6, 2020
    Assignee: SHANGHAI SYNERGY PHARMACEUTICAL SCIENCES CO., LTD
    Inventors: Yunfei Li, Xiaoer Xia, Xin Xu, Zhen Zhang, Lei Liu, Xiaojuan Zhang, Liming Zhang, Dongsheng Li, Yijin Wang, Jian Ge
  • Vortioxetine pamoic acid salt and crystal form thereof
    Publication number: 20190169147
    Abstract: The present application provides a vortioxetine pamoic acid salt, which includes a crystal form, a solvate or an amorphous substance of the vortioxetine pamoic acid salt. The present application provides a preparation method and use of the vortioxetine pamoic acid salt and the crystal form thereof. The vortioxetine pamoic acid salt prepared in the present application prolongs the residence time of the vortioxetine in vivo, achieving a slow release of the vortioxetine in vivo, and is suitable for preparing a long-acting dosage form.
    Type: Application
    Filed: March 28, 2017
    Publication date: June 6, 2019
    Inventors: Yunfei LI, Xiaoer XIA, Xin XU, Zhen ZHANG, Lei LIU, Xiaojuan ZHANG, Liming ZHANG, Dongsheng LI, Yijin WANG, Jian GE