Abstract: An interaction method and apparatus and an electronic device. The method comprises: displaying a first application interface, wherein the first application interface comprises an interface of a first application; and creating a second application account in the first application interface, wherein the second application account is used for logging in a second application. Therefore, a new interaction mode is provided.

Abstract: A display panel includes a base substrate and a flexible substrate layer. The base substrate includes a flat portion and a curved portion extending from the flat portion and curved towards a side of the base substrate facing away a display surface of the display panel. The flexible substrate layer includes a first portion on a side of the base substrate facing the display surface and a second portion on a side of the base substrate facing away from the display surface. The first portion includes a pixel circuit and the second portion includes a signal line electrically connected to the pixel circuit. The display panel further includes a support structure including a support surface facing away from the display surface, the second portion is coupled to the support surface, and a plane of the support surface intersects a plane of the flat portion of the base substrate.

Abstract: Implementations of the subject technology described herein provide for spatial modeling of enclosed environments for guiding charging beams wirelessly to portable electronic devices within the enclosed environment. For example, a mapping sensor, such as an ultra-wideband (UWB) sensor may be used to generate a spatial model of the enclosed space and/or to determine the location of one or more occupants within the enclosed space. The charging beams can be guided based on the spatial model to avoid objects and/or occupants within the enclosed space that would otherwise block the wireless charging beam.

Abstract: Provided are a method for preparing genetically engineered erythrocytes carrying an anti-PD-1 single chain antibody, and genetically engineered erythrocytes carrying the anti-PD-1 single chain antibody. The preparation method comprises the following steps: constructing a desired fragment sequence in a lentiviral expression vector, lentivirally packaging the vector of the desired sequence to obtain a high-titer lentiviral concentrate; isolating Lin?CD34? cells from peripheral blood mononuclear cells and enriching the Lin?CD34? cells; inducing the Lin?CD34? cells to differentiate into erythroid and performing proliferation thereon; using the lentiviral concentrate to infect the Lin?CD34? cells; and obtaining mature anti-PD-1 scFv erythrocytes via erythrocyte denucleation. The present genetically engineered erythrocytes carrying the anti-PD-1 single chain antibody can perform the targeted delivery of an anti-PD-1 single-chain antibody to tumor tissues.

Abstract: Provided is a method for covalently modifying at least one membrane protein of a red blood cell (RBC), comprising contacting the RBC with a sortase substrate that comprises a sortase recognition motif and an agent, in the presence of a sortase under conditions suitable for the sortase to conjugate the sortase substrate to the at least one membrane protein of the RBC by a sortase-mediated reaction, wherein the sortase recognition motif comprising an optionally substituted hydroxyl carboxylic acid d located at position 5 from the direction of N-terminal to C-terminal. Also provided is a red blood cell (RBC) having an agent linked thereto obtained by the method, as well as the use of the RBC for delivering agents such as drugs and probes.

Abstract: Provided are peripheral red blood cell micronuclei DNA, a method for extracting the same, and the use of the micronuclei DNA in cancer screening, diagnosis, typing and/or staging.

Abstract: A red blood cell (RBC) having an agent linked thereto, wherein the agent is linked to at least one endogenous, non-engineered membrane protein of the RBC by a sortase-mediated reaction, preferably by a sortase-mediated glycine conjugation and/or a sortase-mediated lysine side chain ?-amino group conjugation, which may occurring at least on glycine (n) and/or lysine ?-amino group at internal sites of the extracellular domain of at least one endogenous, non-engineered membrane protein, preferably n being 1 or 2, as well as the use of the RBC for delivering drugs and probes.

Abstract: A population of early-stage burst-forming unit-eryhtoid (BFU-E) cells characterized by low expression of the Type III Transforming Growth Factor ? Receptor (TGFRPIII) and uses thereof for producing red blood cells in vitro, genotoxicity analysis of chemicals, drug sensitivity assessment, and drug development. Also described herein are methods for producing the population of early-stage BFU-E cells and methods for producing red blood cells.

Abstract: The present disclosure provides a method for producing red blood cells by using peripheral blood as well as the produced red blood cells.

Abstract: The present disclosure provides a solar heat absorber including: an inlet through which a heat collecting medium enters the solar heat absorber; a passage member configured to be fluidly connected with the inlet such that the heat collecting medium enters the passage member through the inlet; and a collection member configured to be fluidly connected with the passage member such that the heat collecting medium enters the collection member through the passage member. In the solar heat absorber according to the present disclosure, the ceramic particles are used as the heat collecting medium. In addition, the present disclosure also provides a solar heat collecting system including the solar heat absorber, and a solar power generation system including the solar heat collecting system.

Abstract: The present disclosure provides a solar heat absorber including: an inlet through which a heat collecting medium enters the solar heat absorber; a passage member configured to be fluidly connected with the inlet such that the heat collecting medium enters the passage member through the inlet; and a collection member configured to be fluidly connected with the passage member such that the heat collecting medium enters the collection member through the passage member. In the solar heat absorber according to the present disclosure, the ceramic particles are used as the heat collecting medium. In addition, the present disclosure also provides a solar heat collecting system including the solar heat absorber, and a solar power generation system including the solar heat collecting system.

Abstract: The present invention relates to a synthesis process of suvorexant, novel compounds represented by formulas II, III, IV or V, or salts thereof for preparing suvorexant, and a method for preparing the intermediates. The preparation method uses a chiral starting material to synthesize chiral compounds represented by formulas II, III, IV or V, the compounds obtained being used for synthesizing the suvorexant. The preparation method has the advantages of simple operation, low cost, mild reaction conditions, simple post-treatment, easy to purify, high yield, high ee value for the product, and easy to industrialize. In the reaction route shown, R represents benzyl, allyl or 1-phenethyl, or optionally substituted benzyl at the 2 position to 6 position, such as 4-methoxybenzyl, 4-nitrobenzyl, 2-methylbenzyl, 4-chlorobenzyl or 3-fluorobenzyl.

Abstract: A population of early-stage burst-forming unit-eryhtoid (BFU-E) cells characterized by low expression of the Type III Transforming Growth Factor ? Receptor (TGFRPIII) and uses thereof for producing red blood cells in vitro, genotoxicity analysis of chemicals, drug sensitivity assessment, and drug development. Also described herein are methods for producing the population of early-stage BFU-E cells and methods for producing red blood cells.

Abstract: The present invention relates to a synthesis process of suvorexant, novel compounds represented by formulas II, III, IV or V, or salts thereof for preparing suvorexant, and a method for preparing the intermediates. The preparation method uses a chiral starting material to synthesize chiral compounds represented by formulas II, III, IV or V, the compounds obtained being used for synthesizing the suvorexant. The preparation method has the advantages of simple operation, low cost, mild reaction conditions, simple post-treatment, easy to purify, high yield, high ee value for the product, and easy to industrialize. In the reaction route shown, R represents benzyl, allyl or 1-phenethyl, or optionally substituted benzyl at the 2 position to 6 position, such as 4-methoxybenzyl, 4-nitrobenzyl, 2-methylbenzyl, 4-chlorobenzyl or 3-fluorobenzyl.

Abstract: The present invention provides a GPU-based particle flow simulation system and method which includes generating particle information based on particle modeling information inputted from a client terminal, and generating geometric solid information; receiving the particle information and the geometric solid information, determining which GPUs of which computation nodes are to be used based on the number of the particles and the number of idle GPUs in each of the computation nodes; determining which particles are to be processed in which GPUs of which computation nodes based on the determined number of GPUs and a space distribution of the particles, and performing allocation according to the determination result; stimulating particle flow by computing in parallel in the plurality of GPUs a force applied to each particle due to particle collision and thus an acceleration; and presenting a stimulation result.

Abstract: The present invention provides a GPU-based particle flow simulation system and method which includes generating particle information based on particle modeling information inputted from a client terminal, and generating geometric solid information; receiving the particle information and the geometric solid information, determining which GPUs of which computation nodes are to be used based on the number of the particles and the number of idle GPUs in each of the computation nodes; determining which particles are to be processed in which GPUs of which computation nodes based on the determined number of GPUs and a space distribution of the particles, and performing allocation according to the determination result; stimulating particle flow by computing in parallel in the plurality of GPUs a force applied to each particle due to particle collision and thus an acceleration; and presenting a stimulation result.