Patents by Inventor Xiaofei Liang
Xiaofei Liang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11965037Abstract: Provided is an anti-HER3 humanized monoclonal antibody. The antibody binds HER3 antigen, has high affinity and biological activity and low immunogenicity, and is stable in structure. The antibody can be used for preparing drugs for preventing or treating HER3-related diseases.Type: GrantFiled: July 17, 2019Date of Patent: April 23, 2024Assignee: SHANGHAI INSTITUTE OF BIOLOGICAL PRODUCTS CO., LTD.Inventors: Aidong Qu, Hongyuan Liang, Fanhong Xu, Aoxiang Li, Lina Wu, Jingye Zhu, Jianhua Qiu, Jin Lu, Lin Zhang, Xin Zhao, Xiaofei Song
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Publication number: 20240127186Abstract: An interaction method and apparatus and an electronic device. The method comprises: displaying a first application interface, wherein the first application interface comprises an interface of a first application; and creating a second application account in the first application interface, wherein the second application account is used for logging in a second application. Therefore, a new interaction mode is provided.Type: ApplicationFiled: December 21, 2023Publication date: April 18, 2024Inventors: Xiaoping ZHANG, Yunsheng HAO, Jialu WANG, Yi WEI, Pengzhan XU, Guichao REN, Boyu ZHOU, Zitian GUO, Yuxiang LI, Jieli LIANG, Xiaofei GAO, Daozhi LIN, Hong ZOU, Wentao LIU, Zheng CHEN, Shanshan LING
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Patent number: 11959238Abstract: A system for a sandy soil landfill solid waste polluted river channel, includes a ground water interception and diversion system and a river channel ecological remediation system. The ground water interception and diversion system includes a water intake well arranged upstream of ground water in a landfill area, a buffer pool communicated with the water intake well, and a wastewater treatment system communicated with the buffer pool. The water intake well, the buffer pool, and the wastewater treatment system are communicated through a wastewater pipe. An electric wastewater valve and a variable frequency water pump are arranged on the wastewater pipe in sequence. The river channel ecological remediation system includes an impermeable layer arranged at a bottom of a river channel and ecological bank protections arranged on both sides of a river channel slope.Type: GrantFiled: November 24, 2023Date of Patent: April 16, 2024Assignee: Nanjing Institute of Environmental Sciences, MEEInventors: Houhu Zhang, Xiaofei Yan, Jinglong Liu, Lichen Liang, Congcong Sun, Xiang Chen, Cheng Zhang
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Patent number: 11959160Abstract: Disclosed is a copper-niobium alloy for a medical biopsy puncture needle. A needle core and/or needle tube of the puncture needle are/is made of the copper-niobium alloy. The copper-chromium alloy includes the following components by mass: 5?Nb?15 and the balance of Cu. A copper alloy with designed components is obtained by combining a diamagnetic material Cu with paramagnetic Nb, and compared with existing medical stainless steel and titanium alloy, the copper alloy has greatly reduced magnetic susceptibility, and specifically, the artifact area and volume are also significantly reduced. In addition, the blank of use of the copper alloy in medical biopsy paracentesis is filled.Type: GrantFiled: July 8, 2022Date of Patent: April 16, 2024Assignee: University of Shanghai for Science and TechnologyInventors: Xiaohong Chen, Xiaofei Liang, Honglei Zhou, Jian Zhao, Ping Liu, Shaoli Fu
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Patent number: 11928644Abstract: The disclosure provides an articles picking method, a control system and an articles picking system, and relates to the technical field of intelligent warehousing. The articles picking method of the present disclosure includes: receiving an order of a single articles picking point of an AGV arriving at an articles picking point, the order of the single articles picking point comprising information of articles belonging to a same articles picking point in one or more orders associated with the AGV; recommending the order of the single articles picking point to articles pickers of no less than a predetermined number; setting the order of the single articles picking point to be an assigned state to avoid the order of the single articles picking point being picked repeatedly in the event that there is an articles picker taking the order of the single articles picking point.Type: GrantFiled: May 15, 2019Date of Patent: March 12, 2024Assignee: BEIJING JINGDONG QIANSHI TECHNOLOGY CO., LTD.Inventors: Zhikang Liang, Xiaofei Qi
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Patent number: 11602534Abstract: The present invention relates to a kinase inhibitor, comprising a compound of Formula I or a pharmaceutically acceptable salt, solvate, ester, acid, metabolite or prodrug thereof. The present invention also relates to a pharmaceutical composition comprising the kinase inhibitor, and to uses and methods for using these compounds and compositions to inhibit the activity of wild-type FLT3, mutant FLT3-ITD, PDGFR? and/or PDGFR? kinase in a cell or a subject, as well as uses and methods of these compounds and compositions to preventing or treating kinase-associated conditions in a subject.Type: GrantFiled: December 26, 2017Date of Patent: March 14, 2023Assignee: Hefei Institutes of Physical Science, Chinese Academy of SciencesInventors: Qingsong Liu, Jing Liu, Xiaofei Liang, Beilei Wang, Kailin Yu, Zongru Jiang, Cheng Chen, Chen Hu, Wenchao Wang, Fengming Zou, Qingwang Liu, Feng Li, Wenliang Wang, Li Wang
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Publication number: 20230043705Abstract: The present disclosure discloses a copper-niobium alloy for a medical biopsy puncture needle. A needle core and/or needle tube of the puncture needle are/is made of the copper-niobium alloy. The copper-chromium alloy includes the following components by mass: 5?Nb?15 and the balance of Cu. According to the present disclosure, a copper alloy with designed components is obtained by combining a diamagnetic material Cu with paramagnetic Nb, and compared with existing medical stainless steel and titanium alloy, the copper alloy has greatly reduced magnetic susceptibility, and specifically, the artifact area and volume are also significantly reduced. In addition, the blank of use of the copper alloy in medical biopsy paracentesis is filled.Type: ApplicationFiled: July 8, 2022Publication date: February 9, 2023Applicant: University of Shanghai for Science and TechnologyInventors: Xiaohong CHEN, Xiaofei LIANG, Honglei ZHOU, Jian ZHAO, Ping LIU, Shaoli FU
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Publication number: 20220024931Abstract: The present application relates to a compound serving as a selective PI3K? kinase inhibitor, comprising the compound shown in formula (I) or a pharmaceutically acceptable salt, solvate, ester, acid, metabolite or prodrug thereof, wherein X, R1, R2, R3, R4, R5 and R6 are as defined in the description. The present application also relates to a method for using the kinase inhibitor to inhibit PI3K? kinase activity or to treat or prevent diseases or conditions associated with tyrosine kinase activity of PI3K?, as well as a use thereof.Type: ApplicationFiled: December 12, 2018Publication date: January 27, 2022Applicant: TARAPEUTICS SCIENCE INC.Inventors: Qingsong LIU, Jing LIU, Xiaofei LIANG, Feng LI, Ziping QI, Zongru JIANG, Qingwang LIU, Kailin YU, Zhenquan HU, Beilei WANG, Li WANG
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Publication number: 20210206715Abstract: Disclosed are compounds of formulae: and pharmaceutically acceptable salts thereof, wherein the variables, R1, R2, R3, R4, R5, R6, R7, R11, R12, R13, R14, R15, R16, R17, n, and m are defined herein. These compounds are useful for treating Gram-negative bacteria infections. Also disclosed are methods of making these compounds.Type: ApplicationFiled: March 19, 2021Publication date: July 8, 2021Applicants: Duke University, The University of North Carolina at Chapel HillInventors: Pei Zhou, Eric J. Toone, Robert A. Nicholas, Ramesh Gopalaswamy, Xiaofei Liang, Frank Navas, III
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Patent number: 11034649Abstract: Disclosed are compounds of formulae: and pharmaceutically acceptable salts thereof, wherein the variables, R1, R2, R3, R4, R5, R6, R7, R11, R12, R13, R14, R15, R16, R17, n, and m are defined herein. These compounds are useful for treating Gram-negative bacteria infections. Also disclosed are methods of making these compounds.Type: GrantFiled: April 25, 2017Date of Patent: June 15, 2021Assignees: DUKE UNIVERSITY, THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILLInventors: Pei Zhou, Eric J. Toone, Robert A. Nicholas, Ramesh Gopalaswamy, Xiaofei Liang, Frank Navas, III
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Publication number: 20200323850Abstract: The present invention relates to a kinase inhibitor, comprising a compound of Formula I or a pharmaceutically acceptable salt, solvate, ester, acid, metabolite or prodrug thereof. The present invention also relates to a pharmaceutical composition comprising the kinase inhibitor, and to uses and methods for using these compounds and compositions to inhibit the activity of wild-type FLT3, mutant FLT3-ITD, PDGFR? and/or PDGFR? kinase in a cell or a subject, as well as uses and methods of these compounds and compositions to preventing or treating kinase-associated conditions in a subject.Type: ApplicationFiled: December 26, 2017Publication date: October 15, 2020Applicant: HEFEI INSTITUTES OF PHYSICAL SCIENCE, CHINESE ACADEMY OF SCIENCESInventors: Qingsong LIU, Jing LIU, Xiaofei LIANG, Beilei WANG, Kailin YU, Zongru JIANG, Cheng CHEN, Chen HU, Wenchao WANG, Fengming ZOU, Qingwang LIU, Feng LI, Wenliang WANG, Li WANG
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Patent number: 10550074Abstract: Disclosed are compounds of formulae: and pharmaceutically acceptable salts thereof, wherein the variables, R1, R2, R3, R4, R5, R6, R7, R11, R12, R13, R14, R15, R16, R17, n, and m are defined herein. These compounds are useful for treating Gram-negative bacteria infections. Also disclosed are methods of making these compounds.Type: GrantFiled: February 7, 2019Date of Patent: February 4, 2020Assignees: DUKE UNIVERSITY, THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILLInventors: Pei Zhou, Eric J. Toone, Robert A. Nicholas, Ramesh Gopalaswamy, Xiaofei Liang, Frank Navas, III
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Publication number: 20190367446Abstract: Disclosed are compounds of formulae: and pharmaceutically acceptable salts thereof, wherein the variables, R1, R2, R3, R4, R5, R6, R7, R11, R12, R13, R14, R15, R16, R17, n, and m are defined herein. These compounds are useful for treating Gram-negative bacteria infections. Also disclosed are methods of making these compounds.Type: ApplicationFiled: April 25, 2017Publication date: December 5, 2019Inventors: Pei Zhou, Eric J. Toone, Robert A. Nicholas, Ramesh Gopalaswamy, Xiaofei Liang, Frank Navas, III
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Publication number: 20190169114Abstract: Disclosed are compounds of formulae: and pharmaceutically acceptable salts thereof, wherein the variables, R1, R2, R3, R4, R5, R6, R7, R11, R12, R13, R14, R15, R16, R17, n, and m are defined herein. These compounds are useful for treating Gram-negative bacteria infections. Also disclosed are methods of making these compounds.Type: ApplicationFiled: February 7, 2019Publication date: June 6, 2019Inventors: Pei Zhou, Eric J. Toone, Robert A. Nicholas, Ramesh Gopalaswamy, Xiaofei Liang, Frank Navas, III