Abstract: The present invention discloses a wire rod for an ultrahigh-strength steel cord and a manufacturing method thereof. The manufacturing method includes: smelting molten steel where inclusions in sizes ?5 ?m are at a number density ?0.5/mm2 and sizes of inclusions are ?30 ?m; casting the molten steel into an ingot blank with a center carbon segregation value of 0.92-1.08; cogging the ingot blank into an intermediate blank with a center carbon segregation value of 0.95-1.05; rolling the intermediate blank into a wire rod; and performing temperature control cooling on the wire rod to obtain a wire rod with high purity, high homogeneity and tensile strength ?1,150 MPa. The wire rod may be used for an ultrahigh-strength steel cord with single tensile strength ?3,600 MPa.

Abstract: The present disclosure relates to a pyrrolo benzodiazepine derivative and a conjugate, preparation method and use thereof. In particular, the present disclosure relates to a compound of formula (DL) and a antibody-drug conjugate thereof, a pharmaceutical composition containing same, and a use thereof in the preparation of a medicament for the treatment of cancer. The definitions of groups in the general formula (DL) are as defined in the description.

Abstract: The present invention discloses a wire rod for an ultrahigh-strength steel cord and a manufacturing method thereof. The manufacturing method includes: smelting molten steel where inclusions in sizes ?5 ?m are at a number density ?0.5/mm2 and sizes of inclusions are ?30 ?m; casting the molten steel into an ingot blank with a center carbon segregation value of 0.92-1.08; cogging the ingot blank into an intermediate blank with a center carbon segregation value of 0.95-1.05; rolling the intermediate blank into a wire rod; and performing temperature control cooling on the wire rod to obtain a wire rod with high purity, high homogeneity and tensile strength ?1,150 MPa. The wire rod may be used for an ultrahigh-strength steel cord with single tensile strength ?3,600 MPa.

Abstract: The present invention relates to a ligand-drug conjugate of an exatecan analogue, a preparation method therefor and an application thereof. Specifically, the present invention provides a ligand-drug conjugate having a structure shown in formula (-D), a preparation method therefor, a pharmaceutical composition containing same, and use thereof in preparation of drugs for treating cancers by means of receptor regulation. The definition of each substituent in formula (-D) is the same as that in the description.

Abstract: Methods, systems, and computer readable media may be operable to facilitate the capture of a segment of a media stream. A media segment may be captured from a media stream in response to a received media segment capture request. A media segment type may be determined from a default setting or from a received user command identifying the desired media segment type. Based on the determined media segment type, the captured media segment may be converted to a media format associated with the media segment type, and the converted media segment may be stored or output to an external sever or client device. Information associated with the media segment or media stream from which the media segment is captured may be retrieved from the media stream or user input and may be added to the converted media segment as metadata.