Abstract: The present disclosure discloses an adaptive beam collimation and quality optimization system and method based on spot gridding, which belongs to the field of laser transmission.

Abstract: Provided in the present disclosure are a compound for inhibiting the expression of the LPA gene, a pharmaceutical composition and the use thereof, which belong to the technical field of small nucleic acid drug delivery. The oligonucleotide-conjugated compound and the pharmaceutical composition thereof provided in the present disclosure can significantly inhibit the expression of LPA mRNA in animal liver tissues. The oligonucleotide-conjugated compound and the pharmaceutical composition thereof provided in the present disclosure are helpful for relieving, preventing and/or treating diseases or conditions mediated by LPA gene expression dysregulation. AA Relative expression level of LPA mRNA (%) BB Level of LPA mRNA in liver tissues of Balb/c-HDI mice CC s.c.

Abstract: Provided are a compound for inhibiting angiotensinogen (AGT) gene expression, and a pharmaceutical composition and the use thereof, which belong to the technical field of small nucleic acid drug delivery. The provided oligonucleotide-conjugated compound and a pharmaceutical composition thereof can induce silencing complex (RISC)-mediated cleavage of RNA transcripts of the AGT gene, thereby inhibiting the expression of the AGT gene. The provided oligonucleotide-conjugated compound and the pharmaceutical composition thereof help to alleviate, prevent and/or treat diseases or conditions mediated by the AGT gene.

Abstract: An information processing system, a setting change method, and a non-transitory recording medium. The information processing system registers a plurality of access accounts for managing the plurality of information processing apparatuses, transmits, in response to receiving an acquisition request from a particular information processing apparatus of the plurality of information processing apparatuses, the plurality of access accounts to the particular information processing apparatus, determines whether the plurality of access accounts satisfy a requisite based on authority information set in the particular information processing apparatus and stores one of the plurality of access accounts that satisfies the requisite.

Abstract: The present invention provides low glycemic index (GI) total nutrition formula emulsion and a preparation method therefor. The low GI total nutrition formula emulsion comprises the following raw material components in parts by weight: 10-14 parts of carbohydrates, 4-5 parts of calcium caseinate, 1.3-2 parts of dietary fiber, 0.1-0.15 part of sodium chloride, 0.1-0.12 part of sodium citrate, 0.1-0.15 part of potassium citrate, 0.15-0.2 part of magnesium chloride, 0.1-0.15 part of dipotassium hydrogen phosphate, 0.05-0.1 part of compound vitamins, 0.05-0.1 part of compound minerals, 2.5-3.6 parts of compound oil, 0.3-0.5 part of phospholipid, 0.2-0.5 part of medium chain triglyceride (MCT), 0.04-0.08 part of colloids. The preparation method comprises: preparing aqueous phases and oil phases from the raw materials step by step; mixing the aqueous phases and oil phases; and shearing, homogenizing and sterilizing the mixture to obtain the low GI total nutrition emulsion.

Abstract: Provided are modified double-stranded oligonucleotide (dsRNA) molecule, double-stranded oligonucleotide conjugate, and use thereof, which are related to technical field of nucleic acid drugs. Double-stranded oligonucleotide comprises sense strand and an antisense strand; positions 1-9 counting from 5? end of antisense strand comprise at least one modified nucleotide NM, nucleotide NM being nucleotide having modified 2?-silicon-atom-containing group; and spatial volume of 2?-silicon-atom-containing group being greater than that of 2?-methoxy group (2?-OMe). Double-stranded oligonucleotide modified using said method can maintain activity and Tm value of double-stranded oligonucleotide molecules while effectively reducing off-target effects thereof.

Abstract: A compound for inhibiting C3 gene expression, a pharmaceutical composition and a use thereof, belonging to the technical field of small nucleic acid drug delivery. A compound conjugated with an oligonucleotide and a pharmaceutical composition thereof can significantly inhibit the expression of C3 mRNA in animal liver tissue and C3 protein in serum and can reduce C3 deposition in renal tissue and improve the course of disease featuring C3 deposition in renal tissue. The no-adverse-effect level (NOAEL) in SD rats and cynomolgus monkeys is 300 mg/kg. The compound conjugated with a oligonucleotide and the pharmaceutical composition thereof are helpful in alleviating, preventing and/or treating diseases or conditions mediated by dysregulated C3 gene expression.

Abstract: An output system, a system, and an output method. The output system communicates with an output apparatus and an information processing apparatus, and transmits, in response to a request from the output apparatus for electronic data including source identification information received from the information processing apparatus, electronic data associated with a user identified based on the source identification information to the output apparatus.

Abstract: An output apparatus, an information processing system, an output method, and a non-transitory recording medium. The output apparatus receives setting information related to use of the output apparatus from a user terminal of a user and controls based on the setting information, whether to output electronic data received from a service providing system, or to receive list information indicating a list of electronic data from the service providing system and output the electronic data selected from the list information by the user.

Abstract: An image forming apparatus includes circuitry; and a memory storing computer-executable instructions that cause the circuitry to execute determining an authentication method that is available for use for login, based on both a setting of the authentication method for login that is acquired via a network and the setting of the authentication method for login that is set in the image forming apparatus; and displaying, on the image forming apparatus, a login screen corresponding to the authentication method that is available for use.

Abstract: An output apparatus, an information processing system, an output method, and a non-transitory recording medium. The output apparatus receives setting information related to use of the output apparatus from a user terminal of a user and controls based on the setting information, whether to output electronic data received from a service providing system, or to receive list information indicating a list of electronic data from the service providing system and output the electronic data selected from the list information by the user.

Abstract: An information processing device to be a subject of appliance registration in a management server includes a first acquirer configured to acquire identification information for identifying the information processing device; an appliance registration requester configured to transmit an appliance registration request to the management server, the appliance registration request being for the appliance registration in the management server to associate the identification information acquired by the first acquirer with tenant information for identifying a tenant; and a second acquirer configured to acquire a setting value for use in processing an application to be installed in the information processing device; and a writer configured to write, to a storage, a setting value for the application acquired by the second acquirer.

Abstract: An information processing system, a setting change method, and a non-transitory recording medium. The information processing system registers a plurality of access accounts for managing the plurality of information processing apparatuses, transmits, in response to receiving an acquisition request from a particular information processing apparatus of the plurality of information processing apparatuses, the plurality of access accounts to the particular information processing apparatus, determines whether the plurality of access accounts satisfy a requisite based on authority information set in the particular information processing apparatus and stores one of the plurality of access accounts that satisfies the requisite.

Abstract: An output system, a system, and an output method. The output system communicates with an output apparatus and an information processing apparatus, and transmits, in response to a request from the output apparatus for electronic data including source identification information received from the information processing apparatus, electronic data associated with a user identified based on the source identification information to the output apparatus.

Abstract: An output system, a system, and an output method. The output system communicates with an output apparatus and an information processing apparatus, and transmits, in response to a request from the output apparatus for electronic data including source identification information received from the information processing apparatus, electronic data associated with a user identified based on the source identification information to the output apparatus.

Abstract: An image forming apparatus includes circuitry; and a memory storing computer-executable instructions that cause the circuitry to execute determining an authentication method that is available for use for login, based on both a setting of the authentication method for login that is acquired via a network and the setting of the authentication method for login that is set in the image forming apparatus; and displaying, on the image forming apparatus, a login screen corresponding to the authentication method that is available for use.

Abstract: An authentication system includes a shared terminal; and at least one information processing apparatus coupled to the shared terminal via a communication network. The shared terminal includes an authentication controller configured to, upon detecting that the shared terminal is activated, acquire authentication screen data, from the at least one information processing apparatus, for authentication performed for using an internal function of the shared terminal, display an authentication screen based on the acquired authentication screen data, and transmit, to the at least one information processing apparatus, input information that is input to the displayed authentication screen by a user; and an internal function operator configured to display a screen for using the internal function of the shared terminal, upon acquiring information indicating that an authentication process, which is performed based on the input information at the at least one information processing apparatus, is successful.

Abstract: An output system, a system, and an output method. The output system communicates with an output apparatus and an information processing apparatus, and transmits, in response to a request from the output apparatus for electronic data including source identification information received from the information processing apparatus, electronic data associated with a user identified based on the source identification information to the output apparatus.

Abstract: An information processing apparatus includes a screen information request receiver, an application identification information specifying unit, a screen information transmitter. The screen information request receiver receives, from a device, a screen information request used to request screen information for providing an application. The screen information includes at least dealer information representing a dealer that sells the device. The application identification information specifying unit specifies application identification information corresponding to the dealer information included in the screen information request based on application correspondence relation information representing a correspondence relation between the dealer information and the application identification information identifying an application available to the device.