Patents by Inventor Xiaogang LAI

Xiaogang LAI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DIHYDROISOQUINOLINE COMPOUND
    Publication number: 20220081434
    Abstract: The present disclosure provides a series of dihydroisoquinoline compounds or a pharmaceutically acceptable salt, ester, isomer, solvate, hydrate, prodrug, or isotopically labeled compounds thereof, having the structure of general formula I: (I). The compounds have an extremely strong activity for inhibiting Hepatitis B surface antigen and has an extremely strong activity for inhibiting Hepatitis B virus DNA. In addition, the compounds feature high bioavailability and can exhibit efficacy with a low dosage, which reduces the potential toxicity of the compounds.
    Type: Application
    Filed: January 7, 2020
    Publication date: March 17, 2022
    Inventors: Cheng PENG, Shaoyun ZHANG, Xiaogang LAI, Chaojun GONG, Jian HAN, Baolin XU, Gang ZOU, Danbin LI, Haiqing YUAN, Zhen Jim WU
  • Dihydroisoquinoline compound
    Patent number: 10717730
    Abstract: Compositions containing the compound of general formula I: are disclosed. The compositions be used to prevent or treat hepatitis B virus infection.
    Type: Grant
    Filed: March 11, 2020
    Date of Patent: July 21, 2020
    Assignee: SUZHOU ARK BIOPHARMACEUTICAL CO., LTD.
    Inventors: Cheng Peng, Yang Zhou, Gang Zou, Danbin Li, Haiqing Yuan, Zhen Jim Wu, Xiashi Lv, Xiaogang Lai, Shaoyun Zhang
  • DIHYDROISOQUINOLINE COMPOUND
    Publication number: 20200207755
    Abstract: Compositions containing the compound of general formula I: are disclosed. The compositions be used to prevent or treat hepatitis B virus infection.
    Type: Application
    Filed: March 11, 2020
    Publication date: July 2, 2020
    Inventors: Cheng PENG, Xiashi LV, Xiaogang LAI, Shaoyun ZHANG, Yang ZHOU, Gang ZOU, Danbin LI, Haiqing YUAN, Zhen Jim WU
  • Dihydroisoquinoline compound
    Patent number: 10647712
    Abstract: A compound of general formula I: is disclosed. The compound be used to prevent or treat hepatitis B virus infection.
    Type: Grant
    Filed: January 10, 2018
    Date of Patent: May 12, 2020
    Assignee: SUZHOU ARK BIOPHARMACEUTICAL CO., LTD.
    Inventors: Cheng Peng, Qing Xu, Teng Feng, Xiashi Lv, Xiaogang Lai, Rui Cui, Shaoyun Zhang, Jian Han, Chaojun Gong, Zhaoxiong Cai, Yang Zhou, Gang Zou, Danbin Li, Haiqing Yuan, Zhen Jim Wu
  • DIHYDROISOQUINOLINE COMPOUND
    Publication number: 20190389855
    Abstract: A compound of general formula I: is disclosed. The compound be used to prevent or treat hepatitis B virus infection.
    Type: Application
    Filed: January 10, 2018
    Publication date: December 26, 2019
    Inventors: Cheng PENG, Qing XU, Teng FENG, Xiashi LV, Xiaogang LAI, Rui CUI, Shaoyun ZHANG, Jian HAN, Chaojun GONG, Zhaoxiong CAI, Yang ZHOU, Gang ZOU, Danbin LI, Haiqing YUAN, Zhen Jim WU