Patents by Inventor Xiaoguang Chen

Xiaoguang Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11588055
    Abstract: The present disclosure provides a thin-film transistor and a method for manufacturing the same, an array substrate, and a display device. The thin film transistor of the present disclosure include a plurality of insulating layers, among which at least one insulating layer on the low temperature polysilicon layer comprises organic material, so vias could be formed in the organic material by an exposing and developing process, thereby effectively avoiding the over-etching problem of the low temperature polycrystalline silicon layer caused by dry etching process. By adopting the method for manufacturing the film transistors of the present disclosure, the contact area and uniformity of the drain electrode and the low temperature polysilicon material layer can be increased; the conductivity can be improved; and the production cycle of products can be greatly reduced and thereby improving the equipment capacity.
    Type: Grant
    Filed: September 25, 2018
    Date of Patent: February 21, 2023
    Assignees: ORDOS YUANGSHENG OPTOELECTRONICS CO., LTD., BOE TECHNOLOGY GROUP CO., LTD.
    Inventors: Wei Liu, Yongbo Ju, Xikang Jin, Zhimin Wang, Jianbin Gao, Xiaoguang Chen, Xinbo Zhou, Jianjun Chen
  • Publication number: 20230027290
    Abstract: The technology of this application relates to a V2X communication method and an apparatus. The method includes a first network element obtains UE density information of a first area in which target UE is located, and the first network element sends first information to the target UE based on the UE density information, where the first information is used by the target UE to adjust transmit power of a PC5 interface. The method provided in this application can improve V2X communication quality, and further reduce power consumption of UE. In addition, it can also be avoided that primary responsibility of an accident is transferred to a server, and information received by the UE is determined using global information, so that an error can be reduced.
    Type: Application
    Filed: September 30, 2022
    Publication date: January 26, 2023
    Inventor: Xiaoguang CHEN
  • Patent number: 11534443
    Abstract: The invention relates to quinazoline compounds, the preparation method, use, and the pharmaceutical composition thereof. The said quinazoline compounds, which are represented by Formula (I), are phosphatidylinositol 3-kinase (PI3K) inhibitors, and can be applied to prevent and/or treat PI3K activity-related diseases, such as cancer, immune diseases, cardiovascular diseases, viral infections, inflammation, metabolism/endocrine function disorders or neurological diseases.
    Type: Grant
    Filed: December 26, 2017
    Date of Patent: December 27, 2022
    Assignee: INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES
    Inventors: Heng Xu, Xiaoguang Chen, Songwen Lin, Ming Ji, Jing Jin, Deyu Wu, Chunyang Wang, Yuanhao Lv
  • Patent number: 11518744
    Abstract: The present invention relates to a benzamide compound and a preparation method, use and pharmaceutical composition thereof. The benzamide compound represented by formula (I) is a STAT3 inhibitor, and can be used to prevent and/or treat a disease related to STAT3 activity, such as a tumor, autoimmune disease, renal disease, cardiovascular disease, inflammation, metabolic/endocrine dysfunction, and neurological disease.
    Type: Grant
    Filed: January 30, 2019
    Date of Patent: December 6, 2022
    Assignee: INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES
    Inventors: Heng Xu, Xiaoguang Chen, Songwen Lin, Ming Ji, Nina Xue, Deyu Wu, Jing Jin
  • Publication number: 20220383200
    Abstract: This application relates to a method for constructing a multi-task learning model, an electronic device, and a computer-readable storage medium. The method includes: constructing a search space formed between an input node and a plurality of task nodes by arranging a plurality of subnetwork layers and a plurality of search layers in a staggered manner. A search layer in the plurality of search layers is arranged between two subnetwork layers of the plurality of subnetwork layers. The method includes sampling a path from the input node to each task node of the plurality of task nodes through the search space to obtain a candidate path as a candidate network structure; and training a parameter of the candidate network structure according to sample data, to generate the multi-task learning model for performing a multi-task prediction.
    Type: Application
    Filed: August 8, 2022
    Publication date: December 1, 2022
    Inventors: Xiaokai Chen, Xiaoguang Gu, Libo Fu
  • Patent number: 11479795
    Abstract: The disclosure discloses a genetically engineered strain for sarcosine production as well as a construction method and application. The genetically engineered strain is obtained by using Escherichia coli as a host and by integrating a single copy of imine reductase gene dpkA on its genome; singly copying citrate synthase gene gltA; knocking out glyoxylate cycle inhibitor gene iclR; knocking out malate synthase gene aceB; integrating a single copy of isocitrate lyase gene aceA; integrating a single copy of membrane-bound transhydrogenase gene pntAB; knocking out 2-ketate reductase gene ycdW; integrating a single copy of phosphoenolpyruvate carboxylase gene ppc; and knocking out pyruvate kinase gene pykF. After system metabolism transformation, the engineered strain can synthesize sarcosine with glucose and methylamine as main raw materials. The sarcosine titer can reach 10 g/L after fermentation for 30 h in a 5 L fermenter.
    Type: Grant
    Filed: January 12, 2022
    Date of Patent: October 25, 2022
    Inventors: Xiaoguang Fan, Yuhang Zhou, Huajie Cao, Pei Xie, Jun Yang, Junyu Tian, Ning Chen, Qingyang Xu
  • Patent number: 11457459
    Abstract: A communication mode selection method includes transmitting, in a first communication mode, a vehicle-to-everything (V2X) service between a leading vehicle and a following vehicle that are in a vehicle platoon, obtaining, signal quality of the first communication mode, when the signal quality of the first communication mode meets a first preset condition, sending, a configuration instruction to the following vehicle, where the configuration instruction is used to instruct the following vehicle to communicate with the leading vehicle in a second communication mode, where the second communication mode is a communication mode in which a network device performs forwarding.
    Type: Grant
    Filed: July 16, 2020
    Date of Patent: September 27, 2022
    Assignee: HUAWEI CLOUD COMPUTING TECHNOLOGIES CO., LTD.
    Inventor: Xiaoguang Chen
  • Patent number: 11453898
    Abstract: The present invention belongs to the bioengineering field, and relates to a method for fermentation production of L-theanine by using an Escherichia coli genetically engineered bacterium. The engineered bacterium is obtained by serving a strain as an original strain, wherein the strain is obtained after performing a single copy of T7RNAP, a dual copy of gmas, xylR knockout, and sucCD knockout on an Escherichia coli W3110 genome, and by integrating genes xfp, pta, acs, gltA, and ppc, and knocking out ackA on the genome. The present invention has a high yield, and stable production performance; after 20-25 h, L-theanine has a titer of 75-80 g/L, and the yield is up to 52-55%. The fermentation broth is purified by membrane separation in combination with a cation-anion resin series technique. Moreover, the one-step crystallization yield is 72.3% and the L-theanine final product has a purity of 99%.
    Type: Grant
    Filed: December 31, 2021
    Date of Patent: September 27, 2022
    Assignees: Henan Julong Biological Engineering Co., Ltd, Tianjin University of Science and Technology
    Inventors: Xiaoguang Fan, Xiaodong Liu, Jing Li, Ning Chen, Bochao Liu, Shuai Liu, Chaochao Sun, Yongchao Liu, Jiajia Teng, Mengtao Zhang, Yuanqing Ji, Yuhang Zhou, Qingyang Xu
  • Patent number: 11447148
    Abstract: A vehicle warning method, to avoid misjudgment caused by factors such as map precision and lane infringement of a vehicle, thereby improving warning accuracy. The method includes: A vehicle-to-everything V2X device receives a V2X message corresponding to a first vehicle. The V2X device determines, based on the V2X message, whether the first vehicle is in a warning area. The warning area is determined based on vehicle information of a second vehicle. The vehicle information includes at least position information of the second vehicle and a vehicle size of the second vehicle. The V2X device outputs warning information corresponding to the first vehicle to the second vehicle.
    Type: Grant
    Filed: May 25, 2021
    Date of Patent: September 20, 2022
    Assignee: HUAWEI CLOUD COMPUTING TECHNOLOGIES CO., LTD.
    Inventor: Xiaoguang Chen
  • Publication number: 20220259625
    Abstract: The disclosure discloses a genetically engineered strain for sarcosine production as well as a construction method and application. The genetically engineered strain is obtained by using Escherichia coli as a host and by integrating a single copy of imine reductase gene dpkA on its genome; singly copying citrate synthase gene gltA; knocking out glyoxylate cycle inhibitor gene iclR; knocking out malate synthase gene aceB; integrating a single copy of isocitrate lyase gene aceA; integrating a single copy of membrane-bound transhydrogenase gene pntAB; knocking out 2-ketate reductase gene ycdW; integrating a single copy of phosphoenolpyruvate carboxylase gene ppc; and knocking out pyruvate kinase gene pykF. After system metabolism transformation, the engineered strain can synthesize sarcosine with glucose and methylamine as main raw materials. The sarcosine titer can reach 10 g/L after fermentation for 30 h in a 5 L fermenter.
    Type: Application
    Filed: January 12, 2022
    Publication date: August 18, 2022
    Inventors: Xiaoguang FAN, Yuhang ZHOU, Huajie CAO, Pei XIE, Jun YANG, Junyu TIAN, Ning CHEN, Qingyang XU
  • Patent number: 11393229
    Abstract: Methods and systems for artificial intelligence based medical image segmentation are disclosed. In a method for autonomous artificial intelligence based medical image segmentation, a medical image of a patient is received. A current segmentation context is automatically determined based on the medical image and at least one segmentation algorithm is automatically selected from a plurality of segmentation algorithms based on the current segmentation context. A target anatomical structure is segmented in the medical image using the selected at least one segmentation algorithm.
    Type: Grant
    Filed: November 24, 2020
    Date of Patent: July 19, 2022
    Assignee: Siemens Healthcare GmbH
    Inventors: Shaohua Kevin Zhou, Mingqing Chen, Hui Ding, Bogdan Georgescu, Mehmet Akif Gulsun, Tae Soo Kim, Atilla Peter Kiraly, Xiaoguang Lu, Jin-hyeong Park, Puneet Sharma, Shanhui Sun, Daguang Xu, Zhoubing Xu, Yefeng Zheng
  • Patent number: 11376267
    Abstract: A drug combination for treatment of amyotrophic lateral sclerosis includes chlorogenic acid, vitamin E, vitamin C, coenzyme Q10, and creatine phosphate sodium, as well as pharmaceutically acceptable carriers, in which chlorogenic acid, vitamin E, vitamin C, coenzyme Q10, and creatine phosphate sodium are unit preparations having same or different specifications, that are simultaneously or separately administrated. The combination of chlorogenic acid, vitamin E, vitamin C, coenzyme Q10, and creatine phosphate sodium shows a synergistic effect on amyotrophic lateral sclerosis, thus provides a combination with excellent therapeutic effect on amyotrophic lateral sclerosis, which delays the progression of amyotrophic lateral sclerosis.
    Type: Grant
    Filed: June 28, 2019
    Date of Patent: July 5, 2022
    Assignee: SICHUAN JIUZHANG BIOLOGICAL SCIENCE AND TECHNOLOGY CO., LTD.
    Inventors: Jie Zhang, Xiaoguang Chen, Huarong Yang, Wenbin Li
  • Patent number: 11381943
    Abstract: A method includes obtaining, by a control platform, request information, where the request information carries an identifier of user equipment (UE) and an identifier of a vehicle-mounted device, and sending indication information to the UE based on the request information, where the indication information instructs the UE to disable or enable a vehicle-to-pedestrian (V2P) function to forbid or allow the UE to transmit a V2P message.
    Type: Grant
    Filed: September 23, 2020
    Date of Patent: July 5, 2022
    Assignee: HUAWEI CLOUD COMPUTING TECHNOLOGIES CO., LTD.
    Inventor: Xiaoguang Chen
  • Patent number: 11218852
    Abstract: A communication mode switching method, a network side device, and a terminal device includes a communication mode of the second vehicle to everything (V2X) service is switched from a first communication mode to the second communication mode for scheduling a first V2X service of a radio resource to be transmitted using the first communication mode.
    Type: Grant
    Filed: December 23, 2019
    Date of Patent: January 4, 2022
    Assignee: HUAWEI TECHNOLOGIES CO., LTD.
    Inventor: Xiaoguang Chen
  • Publication number: 20210353580
    Abstract: Chlorogenic acid and/or coumaroylquinic acid are employed in preparation of drugs for treating squamous cell carcinoma. Chlorogenic acid or coumaroylquinic acid can effectively treat squamous cell carcinoma. A combination of chlorogenic acid and coumaroylquinic acid can also achieve effective treatment, can yield a synergistic effect, and has excellent application prospect.
    Type: Application
    Filed: May 10, 2019
    Publication date: November 18, 2021
    Inventors: Jie ZHANG, Xiaoguang CHEN, Wang HUANG
  • Publication number: 20210338622
    Abstract: Chlorogenic acid or compositions containing chlorogenic acid are used in preparation of a medicament for treating sarcoma. The chlorogenic acid composition includes chlorogenic acid and coumaroyl quinic acid, can effectively treat sarcoma, and has a better therapeutic effect than the chemotherapeutic medicament doxorubicin. The experimental results show that the combination of chlorogenic acid and coumaroylquinic acid can have a synergistic effect.
    Type: Application
    Filed: April 24, 2019
    Publication date: November 4, 2021
    Inventors: Jie ZHANG, Xiaoguang CHEN, Wang HUANG
  • Publication number: 20210330626
    Abstract: A pharmaceutical composition contains chlorogenic acid and coumaroyl quinic acid. The combined use of chlorogenic acid and coumaroyl quinic acid at a certain ratio can generate a synergistic enhancing effect to effectively inhibit the growth of human kidney cancer cell strain A479, rat kidney cell strain RuCa, and rat transplanted tumor RuCa, providing a novel choice for clinical treatment of kidney cancer and having good market application prospects.
    Type: Application
    Filed: May 31, 2019
    Publication date: October 28, 2021
    Inventors: Jie ZHANG, Xiaoguang CHEN, Wang HUANG, Ya ZHANG
  • Publication number: 20210328073
    Abstract: The present disclosure provides a thin-film transistor and a method for manufacturing the same, an array substrate, and a display device. The thin film transistor of the present disclosure include a plurality of insulating layers, among which at least one insulating layer on the low temperature polysilicon layer comprises organic material, so vias could be formed in the organic material by an exposing and developing process, thereby effectively avoiding the over-etching problem of the low temperature polycrystalline silicon layer caused by dry etching process. By adopting the method for manufacturing the film transistors of the present disclosure, the contact area and uniformity of the drain electrode and the low temperature polysilicon material layer can be increased; the conductivity can be improved; and the production cycle of products can be greatly reduced and thereby improving the equipment capacity.
    Type: Application
    Filed: September 25, 2018
    Publication date: October 21, 2021
    Inventors: Wei LIU, Yongbo JU, Xikang JIN, Zhimin WANG, Jianbin GAO, Xiaoguang CHEN, Xinbo ZHOU, Jianjun CHEN
  • Publication number: 20210319109
    Abstract: The present disclosure is directed to reducing the secure boot time of software images and includes one or more processors and one or more computer-readable non-transitory storage media coupled to the one or more processors and comprising instructions that, when executed by the one or more processors, cause one or more components to perform operations including identifying a software image for a first secure boot, the software image stored in a persistent storage and comprising a kickstart software package and a system software package, fetching the software image, including the kickstart software package and the system software package, from the persistent storage to a memory, verifying one or more digital signatures associated with the software image, booting the kickstart software package of the software image from the memory, and staging the system software package in the persistent storage.
    Type: Application
    Filed: April 13, 2020
    Publication date: October 14, 2021
    Inventors: Wenwei Weng, Nag Avadhanam, Xiaoguang Chen, Ning Zhao, Christopher A. Stone
  • Patent number: 11135160
    Abstract: Provided are a use of chlorogenic acid in preparing pharmaceuticals for the inhibition of LAG-3 and a use of chlorogenic acid in preparing pharmaceuticals for the treatment of LAG-3-mediated diseases. The inhibition of LAG-3 by chlorogenic acid is useful in cancer therapy, anti-viral therapy, and sepsis treatment. The oral bioavailability of chlorogenic acid is enhanced by preparing chlorogenic acid as a gastric floating tablet.
    Type: Grant
    Filed: February 20, 2017
    Date of Patent: October 5, 2021
    Assignee: SICHUAN JIUZHANG BIOLOGICAL SCIENCE AND TECHNOLOGY CO., LTD
    Inventors: Jie Zhang, Xiaoguang Chen, Nina Xue, Mengtian Zhang