Patents by Inventor Xiaohan Du

Xiaohan Du has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hepatitis B vaccine
    Patent number: 9878035
    Abstract: Disclosed is a composition comprising: i) HBsAg, a fragment thereof, a variant thereof, or the mixture of at least two of them, ii) HBcAg1-X, a fragment thereof, a variant of the antigen or the antigen fragment, or the mixture of at least two of them, wherein X is an integer of from 149 to 183, iii) CpG-ODN, 21 bases long, which is a phosphorothioate oligonucleotide and includes two or more copies of 5?-NTCGTT-3? motifs. The use of the composition in the treatment of HBV-infection and HBV-induced diseases, and the therapy methods of HBV-infection and HBV-induced diseases are also disclosed.
    Type: Grant
    Filed: February 26, 2014
    Date of Patent: January 30, 2018
    Assignee: JIANGSU THERAVAC BIO-PHARMACEUTICAL CO., LTD.
    Inventors: Sean Xiaohan Du, Jun Ge, Xiaoqian Zhuang, Tong Zhou, Jianqiang Li, Cuiling Song, Ying Sun, Meiju Wang, Yue Gu, Honglin Sun, Zhenxing Xu, Hongying Huang, Xiaoxiao Chen
  • HEPATITIS B VACCINE
    Publication number: 20160136264
    Abstract: Disclosed is a composition comprising: i) HBsAg, a fragment thereof, a variant thereof, or the mixture of at least two of them, ii) HBcAg1-X, a fragment thereof, a variant of the antigen or the antigen fragment, or the mixture of at least two of them, wherein X is an integer of from 149 to 183, iii) CpG-ODN, 21 bases long, which is a phosphorothioate oligonucleotide and includes two or more copies of 5?-NTCGTT-3? motifs. The use of the composition in the treatment of HBV-infection and HBV-induced diseases, and the therapy methods of HBV-infection and HBV-induced diseases are also disclosed.
    Type: Application
    Filed: February 26, 2014
    Publication date: May 19, 2016
    Applicant: JIANGSU THERAVAC BIO-PHARMACEUTICAL CO., LTD.
    Inventors: Sean Xiaohan DU, Jun GE, Xiaoqian ZHUANG, Tong ZHOU, Jianqiang LI, Cuiling SONG, Ying SUN, Meiju WANG, Yue GU, Honglin SUN, Zhenxing XU, Hongying HUANG, Xiaoxiao CHEN
  • Chimeric HIV Antigens
    Publication number: 20110262474
    Abstract: The invention provides polynucleotides and polypeptides encoded therefrom that are capable of inducing immune responses to a human immunodeficiency virus. Compositions and methods for utilizing polynucleotides and polypeptides of the invention are also provided.
    Type: Application
    Filed: July 23, 2008
    Publication date: October 27, 2011
    Inventors: Xiaohan Du, Li Xu, Robert Whalen, Kristin M. Ostrow