Abstract: A prestressed fish-belly reaction frame, a pile foundation bearing capacity detection device and application thereof, which includes: a core junction; a reaction beam including a plurality of beam units symmetrically arranged around the core junction with the core junction as a center, each beam unit has a first end and a second end, the first end is connected and fixed to the core junction, and the second end is connected and fixed to a pile top of an anchor pile when the pile foundation bearing capacity is detected; a prestressed assembly including a plurality of prestressed tendons, each prestressed tendon passes through an upper end of the core junction, a first end of each prestressed tendon is connected and fixed to the second end of one beam unit, a second end thereof is connected and fixed to the second end of the symmetrical beam unit.

Abstract: The present invention provides hydrogel-based compositions that are suitable for replacing or supplementing the nucleus pulposus in a subject. The compositions of the invention are useful for treating, ameliorating or reverting degradation of the nucleus pulposus in the subject. The present invention also provides methods of preparing and using such compositions.