Patents by Inventor Xiaohong Hao

Xiaohong Hao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240158480
    Abstract: Disclosed in the present invention is an anti-Nipah virus monoclonal antibody having neutralization activity. The antibody consists of a monkey-derived variable region and a human constant region, and both light and heavy chains of the monkey-derived variable region have unique CDR regions. The antibody provided by the present invention has an excellent antigen binding capability, and has good binding activity with Bangladesh Nipah virus and Malaysia Nipah virus glycoprotein G. The antibody can effectively neutralize the Nipahpseudovirus. Moreover, the neutralization activity of the antibody is enhanced as the concentration of the antibody increases, and nearly 100% neutralization of the Nipahpseudovirus can be achieved at a concentration of 1 ?g/mL. Also disclosed in the present invention is an application of the monoclonal antibody against the Nipah virus glycoprotein G in preparation of a Nipah virus treatment drug.
    Type: Application
    Filed: June 26, 2021
    Publication date: May 16, 2024
    Applicant: ACADEMY OF MILITARY MEDICAL SCIENCE, PLA
    Inventors: Wei Chen, Changming Yu, Yujiao Liu, Pengfei Fan, Guanying Zhang, Yaohui Li, Jianmin Li, Xiangyang Chi, Meng Hao, Ting Fang, Yunzhu Dong, Xiaohong Song, Yi Chen, Shuling Liu
  • Patent number: 10113800
    Abstract: A lance including: a central pipe having a wear-resistant ceramic layer coated on an inner wall thereof; a central casing pipe having a casing pipe groove in an outer wall thereof, in which the central casing pipe is fitted over the central pipe; an intermediate pipe fitted over the central casing pipe, in which a combustion-supporting gas chamber is formed between a front part of the central pipe and the intermediate pipe, and an intermediate pipe groove is formed in an outer wall of the rear part; and an outer casing pipe fitted over the intermediate pipe, in which a cooling medium chamber is formed between a front part of the intermediate pipe and the outer casing pipe, and a cooling medium injection channel is defined by an inner wall of the outer casing pipe and the intermediate pipe groove.
    Type: Grant
    Filed: October 4, 2016
    Date of Patent: October 30, 2018
    Assignee: CHINA ENFI ENGINEERING CORPORATION
    Inventors: Dong Li, Zhenmin Zhang, Liqiong Hu, Kefei Cao, Xiaohong Hao
  • Publication number: 20180094857
    Abstract: The invention provides a lance including: a central pipe having a wear-resistant ceramic layer coated on an inner wall thereof; a central casing pipe having a casing pipe groove in an outer wall thereof, in which the central casing pipe is fitted over the central pipe and has a length less than that of the central pipe; a central pipe fitted over the intermediate pipe, in which a combustion-supporting gas chamber is formed between a front part of the central pipe and the intermediate pipe, an external diameter of a rear part of the intermediate pipe is greater than an external diameter of a front part of the intermediate pipe, and an intermediate pipe groove is formed in an outer wall of the rear part; and an outer casing pipe fitted over the intermediate pipe, in which a cooling medium chamber is formed between the front part of the intermediate pipe and the outer casing pipe, and a cooling medium injection channel is defined by an inner wall of the outer casing pipe and the intermediate pipe groove.
    Type: Application
    Filed: October 4, 2016
    Publication date: April 5, 2018
    Applicant: CHINA ENFI ENGINEERING CORPORATION
    Inventors: Dong Li, Zhenmin Zhang, Liqiong Hu, Kefei Cao, Xiaohong Hao