Patents by Inventor Xiaohong Zhu

Xiaohong Zhu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11919906
    Abstract: Crystalline forms of ACP-196, preparation methods, pharmaceutical compositions and uses thereof in the preparation of drugs for treatment and/or prevention of Bruton's tyrosine kinase (BTK)-mediated disorders such as autoimmune diseases or disorders, heteroimmune diseases or disorders, cancers including lymphoma and inflammatory diseases or disorders. As compared with the known solid form of ACP-196, the crystalline forms of the present invention have advantages in crystallinity.
    Type: Grant
    Filed: December 23, 2020
    Date of Patent: March 5, 2024
    Assignee: Hangzhou SoliPharma Co., Ltd.
    Inventors: Xiaohong Sheng, Xiaoxia Sheng, Tao Zhu
  • Publication number: 20240072531
    Abstract: This invention relates to the technical field of harmonic elimination for ferromagnetic resonance for a voltage transformer (abbreviated as PT), in particular, to a harmonic elimination method for ferromagnetic resonance for an active resistance-matching voltage transformer based on PID-adjustment, including compiling a resistance matching algorithm; designing and building a harmonic elimination control system based on the PID control strategy; presetting an active resistance-matching strategy; designing an engineering scheme for placing resistors.
    Type: Application
    Filed: August 17, 2023
    Publication date: February 29, 2024
    Inventors: Xiaohong ZHU, Lianjing YANG, Fei MAO, Rong ZHANG, Yang YANG, Jiangyun SU, Wenfei FENG, Zhe LI, Pengjin QIU, Jianbin LI, Zhikun HONG, Weirong YANG, Changjiu ZHOU, Yingqiong ZHANG, Rui XU, Guibing DUAN
  • Publication number: 20240069426
    Abstract: A projection curtain is provided in the present invention. The projection curtain at least comprises a reflective layer and one of a colored layer, a diffusion layer, and a Fresnel lens layer. The Fresnel lens layer is a spherical Fresnel lens layer or an aspherical Fresnel lens layer. The Fresnel lens layer comprises a plurality of annular protrusions protruding from a plane, the plurality of annular protrusions are arranged in circular bands. A cross-sectional shape of each annular protrusion along a cross section perpendicular to the plane is a triangular shape or a multi-step shape or a free surface shape. The width of one side of each cross-sectional shape parallel to the plane gradually changes, and gradual change of the cross-sectional shape and the width thereof determines light gathering characteristics of the spherical Fresnel lens layer or the aspherical Fresnel lens layer. A surface of each annular protrusion has scattered microstructures.
    Type: Application
    Filed: January 18, 2022
    Publication date: February 29, 2024
    Applicants: IVTECH JIANGSU CO., LTD., IVTOUCH CO., LTD., SVG TECH GROUP CO., LTD.
    Inventors: Xiaohong ZHOU, Ming ZHU, Donglin PU, Pengfei ZHU, Haoshu ZHU, Rubin SUN, Linsen Chen
  • Patent number: 11824348
    Abstract: The present disclosure relates to the technical field of potential transformer (PT) ferromagnetic resonance elimination, in particular to a PT ferromagnetic resonance elimination method implemented by actively inputting resistance through an electronic load, including the following steps: setting up a PT, and determining a mapping relationship; constructing a resonance elimination control system; and designing the electronic load as an active resonance elimination device. The present disclosure overcomes a contradiction between a magnitude of resonance elimination resistance and winding overload in a PT open delta during single-phase-to-earth fault and fault clearance, and effectively avoids the technical problems of difficult distinguishing between single-phase-to-earth fault characteristics and power frequency resonance characteristics and causing resonance in a single-phase-to-earth fault process.
    Type: Grant
    Filed: May 25, 2023
    Date of Patent: November 21, 2023
    Assignee: QUJING POWER SUPPLY BUREAU OF YUNNAN POWER GRID CO., LTD
    Inventors: Xiaohong Zhu, Yin Yang, Sirao Lu, Yuan Shan, Juntao Zeng, Weirong Yang, Zhe Li, Yu Gong, Wenfei Feng, Shoudong Xu, Yongsheng Ning, Rong Zhang, Qibin Mei, Lianjing Yang, Dekai Chen
  • Publication number: 20230322785
    Abstract: The present invention provides compounds of the structural Formula (I) and pharmaceutically acceptable salts thereof, wherein, are as defined herein, pharmaceutical compositions comprising one or more such compounds (alone and in combination with one or more other therapeutically active agents), and methods for their preparation and use, alone and in combination with other therapeutic agents, as antagonists of A2a and/or A2b receptors, and in the treatment of a variety of diseases, conditions, or disorders that are mediated, at least in part, by the adenosine A2a receptor and/or the adenosine A2b receptor.
    Type: Application
    Filed: July 21, 2022
    Publication date: October 12, 2023
    Applicant: Merck Sharp & Dohme LLC
    Inventors: Amjad Ali, Christopher W. Boyce, Jared N. Cumming, Duane DeMong, Thomas H. Graham, Subrahmanyam Gudipati, Andrew J. Hoover, Xianhai Huang, Rongze Kuang, Jae-Hun Kim, Joseph M. Kelly, Yeon-Hee Lim, Michael Man-Chu Lo, Jesus Moreno, Jing Su, Heping Wu, Dong Xiao, Younong Yu, Xiaohong Zhu
  • Publication number: 20230183275
    Abstract: The present invention provides a system for continuously producing diethyl methylphosphonite, comprising a rapid mixing reactor and a material circulation subsystem. An inlet of the rapid mixing reactor is provided with a rapid mixing component; the rapid mixing component comprises a first liquid inlet and a second liquid inlet: the second liquid inlet is used for feeding a material containing methylphosphonous dichloride; the material circulation subsystem comprises a filter, a material distribution unit, an acid binding agent premixer and a heat exchanger, which are connected in sequence; the filter is also provided with a solid waste outlet; the material distribution unit is also provided with a diethyl methylphosphonite outlet; the acid binding agent premixer is also provided with a reaction raw material inlet and an acid binding agent inlet; an inlet of the filter is connected to an outlet of the rapid mixing reactor; and an outlet of the heat exchanger is connected to the first liquid inlet.
    Type: Application
    Filed: November 18, 2020
    Publication date: June 15, 2023
    Applicants: ZHEJIANG WYNCA CHEMICAL INDUSTRY GROUP CO., LTD, TSINGHUA UNIVERSITY
    Inventors: Tiefeng WANG, Shuguang ZHOU, Xiaocheng LAN, Long QIN, Banghao LI, Shenluan YU, Huahai ZHANG, Shengbao JIANG, Minhai TU, Xiaohong ZHU
  • Patent number: 11528844
    Abstract: An automatic harvesting and collecting device for sisal hemp leaves includes an up-and-down moving assembly, a steering device, a braking mechanism, a mechanical vision sensor device, a vehicle traveling and controlling device, a forward-and-backward moving assembly, an omnidirectional automatic positioning and rotating device, a shearing and clamping device, a collecting device and a frame.
    Type: Grant
    Filed: November 21, 2020
    Date of Patent: December 20, 2022
    Assignee: JIANGXI UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Qingkang Liu, Xiaohong Zhu, Sheng Gao, Yao Zhang, Min Chen, Cijun Shuai
  • Publication number: 20210153437
    Abstract: The present invention relates to the technical field of crop harvesting machinery, in particular to an automatic harvesting and collecting device for sisal hemp leaves, which includes an up-and-down moving assembly, a steering device, a braking mechanism, a mechanical vision sensor device, a vehicle traveling and controlling device, a forward-and-backward moving assembly, an omnidirectional automatic positioning and rotating device, a shearing and clamping device, a collecting device and a frame.
    Type: Application
    Filed: November 21, 2020
    Publication date: May 27, 2021
    Inventors: Qingkang LIU, Xiaohong ZHU, Sheng GAO, Yao ZHANG, Min CHEN, Cijun SHUAI
  • Patent number: 10138212
    Abstract: The present invention is directed to compounds of generic formula I: or pharmaceutically acceptable salts thereof that are believed to be useful as an A2A-receptor antagonist.
    Type: Grant
    Filed: February 1, 2016
    Date of Patent: November 27, 2018
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Amjad Ali, Rongze Kuang, Yeon-Hee Lim, Michael Man-Chu Lo, Pauline C. Ting, Purakkattle Biju, Manuel de Lera Ruiz, Sylvia J. Degrado, Alexander L. Tung, Timothy J. Henderson, Liwu Hong, Jae-Hun Kim, Dong Won-Shik Kim, Joe Lee, Jie Wu, Heping Wu, Yushi Xiao, Tao Yu, Gang Zhou, Xiaohong Zhu, Kevin D. McCormick, Jayaram R. Tagat, Dong Xiao, Tanweer Khan, Jianhua Cao, Michael Berlin, Yonglian Zhang
  • Publication number: 20180037554
    Abstract: The present invention is directed to compounds of generic formula I: or pharmaceutically acceptable salts thereof that are believed to be useful as an A2A-receptor antagonist.
    Type: Application
    Filed: February 1, 2016
    Publication date: February 8, 2018
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Amjad Ali, Rongze Kuang, Yeon-Hee Lim, Michael Man-Chu Lo, Pauline C. Ting, Purakkattle Biju, Manuel de Lera Ruiz, Sylvia J. Degrado, Alexander L. Tung, Timothy J. Henderson, Liwu Hong, Jae-Hun Kim, Dong Won-Shik Kim, Joe Lee, Jie Wu, Heping Wu, Yushi Xiao, Tao Yu, Gang Zhou, Xiaohong Zhu, Kevin D. McCormick, Jayaram R. Tagat, Dong Xiao, Tanweer Khan, Jianhua Cao, Michael Berlin, Yonglian Zhang
  • Patent number: 9406439
    Abstract: The invention relates to a process for forming a lead-based ceramic oxide dielectric material comprising at least one pyrochlore crystalline phase, which process comprises the following steps: a) a step of depositing at least one amorphous layer of said lead-based ceramic oxide material on a substrate; and b) a crystallization annealing step carried out on said amorphous layer at a temperature not exceeding 550° C., by means of which a lead-based ceramic oxide dielectric material comprising at least one pyrochlore phase is obtained. Application to the fabrication of capacitors on integrated circuits.
    Type: Grant
    Filed: September 22, 2009
    Date of Patent: August 2, 2016
    Assignee: COMMISSARIAT A L'ENERGIE ATOMIQUE
    Inventors: Xiaohong Zhu, Emmanuel Defay, Eric Fribourg-Blanc
  • Patent number: 8836535
    Abstract: A mobile network terminal device and method for monitoring the electrophysiological data and a pathological image are provided, including: a baseband processor module, an electrophysiological data collection module, a keyboard module, a graphics and image display module, an image and picture sensor, a voice communication module, an external data memory card, an external data memory, a Bluetooth module, a USB interface module, a GPS receiver module, an application module set and run in the operation system of the baseband processor; an electrophysiological data remote mobile monitoring, a heart pacemaker remote mobile monitoring, a remote consultation appointment, a pathological image remote mobile monitoring, a data exchange, a medical advisory VoIP communication and a network emergency call being performed by the mobile network terminal device under the control of the application module.
    Type: Grant
    Filed: April 21, 2009
    Date of Patent: September 16, 2014
    Inventors: Jinjing Zhang, Yonggang Zhao, Haiqing Gao, Yujie Zhou, Shaowen Liu, Xiaohong Zhu
  • Patent number: 8673900
    Abstract: In many embodiments, the present invention provides novel heterocyclic compounds which are modulators of gamma secretase, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more disease associated with the central nervous system using such compounds or pharmaceutical compositions.
    Type: Grant
    Filed: November 12, 2009
    Date of Patent: March 18, 2014
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Zhaoning Zhu, William J. Greenlee, Xianhai Huang, Jun Qin, Xiaoxiang Liu, Hongmei Li, Wei Zhou, Anandan Palani, Xiaohong Zhu, Monica L. Vicarel, Mihirbaran Mandal, Zhong-Yue Sun, Chad E. Bennett, Troy Michael McCracken, Gioconda V. Gallo
  • Patent number: 8580956
    Abstract: In its many embodiments, the present invention provides a novel class of heterocyclic compounds as modulators of gamma secretase, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the central nervous system using such compounds or pharmaceutical compositions.
    Type: Grant
    Filed: May 28, 2008
    Date of Patent: November 12, 2013
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Zhaoning Zhu, William J. Greenlee, Zhong-Yue Sun, Gioconda Gallo, Ruo Xu, Xianhai Huang, Xiaohong Zhu
  • Patent number: 8518975
    Abstract: This invention provides novel compounds that are modulators of gamma secretase. The compounds have the formula Also disclosed are methods of modulating gamma secretase activity and methods of treating Alzheimer's Disease using the compounds of formula (I).
    Type: Grant
    Filed: September 4, 2008
    Date of Patent: August 27, 2013
    Assignee: Merck Sharp + Dohme Corp.
    Inventors: Robert G. Aslanian, Xianhai Huang, Anandan Palani, Jun Qin, Wei Zhou, Xiaohong Zhu, Robert D. Mazzola, Jr., Pawan Dhondi, William J. Greenlee
  • Patent number: 8450343
    Abstract: This invention provides novel compounds that are modulators of gamma secretase. The compounds have the formula (I) wherein R2 is a fused bicyclic ring of the formula (II). Also disclosed are methods of modulating gamma secretase activity and methods of treating Alzheimer's disease using the compounds of formula (I).
    Type: Grant
    Filed: December 4, 2008
    Date of Patent: May 28, 2013
    Inventors: Xianhai Huang, Anandan Palani, Jun Qin, Robert G. Aslanian, Zhaoning Zhu, William Greenlee, Hubert Josien, Wei Zhou, Xiaohong Zhu, Chad E. Bennett, Dmitri Pissarnitski, Mihirbaran Mandal, Pawan Dhondi, Troy McCracken, Thomas Bara, Zhiqiang Zhao, Duane Burnett, John Clader
  • Patent number: 8357682
    Abstract: The present invention provides a novel class of heterocyclic compounds of Formula (I) as modulators of gamma secretase, wherein the definitions of the variables of Formula (I) are defined herein, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the central nervous system using such compounds or pharmaceutical compositions.
    Type: Grant
    Filed: May 5, 2008
    Date of Patent: January 22, 2013
    Inventors: Zhaoning Zhu, William J. Greenlee, Zhong-Yue Sun, Gioconda Gallo, Theodros Asberom, Xianhai Huang, Xiaohong Zhu, Mark D. McBriar, Dmitri A. Pissarnitski, Zhiqiang Zhao, Ruo Xu, Hongmei Li, Anandan Palani, Johannes H. Voigt, Robert D. Mazzola, Jr., John Clader, Hubert Josien, Jun Qin
  • Patent number: 8111151
    Abstract: A WAN-based remote mobile monitoring method and device of electrophysiological data, including microprocessor circuit, electrophysiological signal sampling processing circuit, data storage circuit, image liquid crystal circuit, real-time clock, emergent calling circuit, working power supply management circuit, wireless network interface circuit, USB interface circuit, etc, has the in-built binding IP address of the remote electrophysiological data monitoring server, TCP/IP protocol, PPP protocol and BlueTooth protocol. Application controls self-adaptive analysis computing, exception event warning and alarming privilege graded setting, event data package combination, network digital communication, data storage circuit area management, safety information data storage management and remote emergent calling of the remote mobile monitoring devices.
    Type: Grant
    Filed: January 15, 2007
    Date of Patent: February 7, 2012
    Inventors: Xiaohong Zhu, Haiqing Gao, Yonggang Zhao, Qichun Chen, Shiang Sun
  • Publication number: 20110294756
    Abstract: In its many embodiments, the present invention provides a novel class of heterocyclic compounds of Group A or Group, as defined herein, as modulators of gamma secretase, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the central nervous system using such compounds or pharmaceutical compositions.
    Type: Application
    Filed: November 12, 2009
    Publication date: December 1, 2011
    Inventors: Zhaoning Zhu, William J., Xianhai Huang, Jun Qin, XIaoxiang Liu, Hongmei Li, Wei Zhou, Anandan Palani, Xiaohong Zhu, Monica L. Vicarel, Mihirbaran Mandal, Zhong-Yue Sun, Chad E. Bennett, Troy Michael McCracken, Gioconda V. Gallo
  • Publication number: 20110273309
    Abstract: A mobile network terminal device and method for monitoring the electrophysiological data and a pathological image are provided, including: a baseband processor module, an electrophysiological data collection module, a keyboard module, a graphics and image display module, an image and picture sensor, a voice communication module, an external data memory card, an external data memory, a Bluetooth module, a USB interface module, a GPS receiver module, an application module set and run in the operation system of the baseband processor; an electrophysiological data remote mobile monitoring, a heart pacemaker remote mobile monitoring, a remote consultation appointment, a pathological image remote mobile monitoring, a data exchange, a medical advisory VoIP communication and a network emergency call being performed by the mobile network terminal device under the control of the application module.
    Type: Application
    Filed: April 21, 2009
    Publication date: November 10, 2011
    Inventors: Jinjing Zhang, Haiqing Gao, Yonggang Zhao, Shaowen Liu, Yujie Zhou, Xiaohong Zhu