Patents by Inventor Xiaohua Wu

Xiaohua Wu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12240904
    Abstract: The present disclosure provides the use of an anti-PD-1 antibody in combination with famitinib in the preparation of a drug for treating tumors. In the present technical solution, toxicity is controllable and tolerable. At the same time, the described drug combination effectively reduces adverse reactions to the anti-PD-1 antibody, such as the occurrence of reactive capillary endothelial proliferation.
    Type: Grant
    Filed: November 5, 2019
    Date of Patent: March 4, 2025
    Assignees: Jiangsu Hengrui Medicine Co., Ltd., Suzhou Suncadia Biopharmaceuticals Co., Ltd.
    Inventors: Lianshan Zhang, Qing Yang, Quanren Wang, Xiaoxing Huang, Cheng Liao, Changyong Yang, Dingwei Ye, Xiaohua Wu
  • Publication number: 20250047387
    Abstract: An optical communication module, a device and a system are provided. The optical communication module includes: an electrical communication unit, an exchanging communication mainboard, a first optical transceiving unit and a second optical transceiving unit. The first optical transceiving unit and the second optical transceiving unit respectively receive an optical signal from and/or send an optical signal to a first device and a second device and complete conversion from or to the optical signal, and by the first optical transceiving unit and the second optical transceiving unit, devices connected with the electrical communication unit, the first device and the second device form a network that has a function of a self-healing ring network.
    Type: Application
    Filed: December 16, 2021
    Publication date: February 6, 2025
    Applicants: CHENGDU POWERVIEW SCIENCE AND TECHNOLOGY CO., LTD., SHENZHEN SH-FIBER TECHNOLOGY CO., LTD.
    Inventors: Xiaohua WU, Xiaolong LI, Fanghai TANG, Ping ZHOU, Zijian XIAO
  • Publication number: 20240407629
    Abstract: Provided are a 3D electronic endoscope and an imaging system for 3D electronic endoscope, including an insertion portion and an operation portion. The insertion portion includes a long tube, an imaging module, an illuminating optical path and a transmission unit. The operation portion includes an operating handle housing, a controller and an processing component for image signal. The controller and the processing component for image signal are arranged in the operating handle housing. The imaging module comprises a first optical path component, a second optical path component, a first sensor, a second sensor, a first flexible board, a second flexible board, and a fixation substrate. The first optical path component comprises a first objective lens group and a first prism group, the second optical path component comprises a second objective lens group and a second prism group. The 3D electronic endoscope is capable of providing an improved image quality.
    Type: Application
    Filed: August 22, 2024
    Publication date: December 12, 2024
    Applicants: Wuhan Mindray Bio-Medical Scientific Co., Ltd., SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.
    Inventors: Yang LI, Xiaowen YUAN, Xiaohua WU
  • Patent number: 11824740
    Abstract: The technology disclosed provides a method of testing handling of HTTPS sessions of a plurality of clients with a plurality of servers by a switching, bridging or routing device (i.e., a DUT), where the testing is conducted by a test system coupled to ports on the DUT. The method includes using client state machines running on at least four processor cores, communicating through the DUT with server state machines running on at least four additional processor cores. The method also includes, for each connection between a client represented by a client state machine and a server represented by a server state machine, setting up an HTTPS session by negotiating an encryption protocol and completing an HTTPS handshake. Further, the method includes following the setup of between 100,000 HTTPS sessions and 10,000,000 HTTPS sessions, conducting a stress test including combining payload data and header information without using the negotiated encryption.
    Type: Grant
    Filed: July 19, 2021
    Date of Patent: November 21, 2023
    Assignee: Spirent Communications, Inc.
    Inventors: Kevin Canady, Richard Wank, Xiaohua Wu, Chunsheng Li
  • Publication number: 20230042576
    Abstract: The present invention discloses an electric sparkling water machine, comprising a machine body, and a water bottle and a gas bottle which are installed on the machine body, wherein the machine body is provided with a control switch and a control board, and the control switch provides a plurality of control gears; the machine body is provided with a movable pressure rod for driving an intake thimble to downward control the gas bottle to inflate the water bottle; the electric sparkling water machine further comprises: a motor connected with the pressure rod through a transmission mechanism for controlling the pressure rod to move; a detection switch for providing signals for the control board; a pressure sensor communicated with an exhaust port of the water bottle for triggering the detection switch; and an exhaust valve connected with the exhaust port of the water bottle.
    Type: Application
    Filed: October 26, 2022
    Publication date: February 9, 2023
    Applicant: Zhejiang Hongfeng Precision Co.,Ltd
    Inventors: Ping Wang, Xiaohua Wu
  • Publication number: 20220251203
    Abstract: The present disclosure provides the use of an anti-PD-1 antibody in combination with famitinib in the preparation of a drug for treating tumors. In the present technical solution, toxicity is controllable and tolerable. At the same time, the described drug combination effectively reduces adverse reactions to the anti-PD-1 antibody, such as the occurrence of reactive capillary endothelial proliferation.
    Type: Application
    Filed: November 5, 2019
    Publication date: August 11, 2022
    Inventors: Lianshan Zhang, Qing Yang, Quanren Wang, Xiaoxing Huang, Cheng Liao, Changyong Yang, Dingwei Ye, Xiaohua Wu
  • Patent number: 11278851
    Abstract: A sparkling water maker capable of automatically controlling gas inflow includes a gas cylinder, a gas cylinder connector mounted on the gas cylinder, a bottle, and a bottle connector mounted on the bottle. A gas guide tube is connected between the gas cylinder connector and the bottle connector. A compressed gas in the gas cylinder is delivered to the bottle through the gas guide tube. The gas guide tube includes a first gas guide tube connected to the gas cylinder connector and a second gas guide tube connected to the bottle connector. A valve is connected between the first gas guide tube and the second gas guide tube. The valve is configured to block a flow passage between the first gas guide tube and the second gas guide tube.
    Type: Grant
    Filed: July 15, 2020
    Date of Patent: March 22, 2022
    Assignee: Zhejiang Hongfeng Precision Co., Ltd.
    Inventors: Xiaohua Wu, Ping Wang
  • Publication number: 20220006711
    Abstract: The technology disclosed provides a method of testing handling of HTTPS sessions of a plurality of clients with a plurality of servers by a switching, bridging or routing device (i.e., a DUT), where the testing is conducted by a test system coupled to ports on the DUT. The method includes using client state machines running on at least four processor cores, communicating through the DUT with server state machines running on at least four additional processor cores. The method also includes, for each connection between a client represented by a client state machine and a server represented by a server state machine, setting up an HTTPS session by negotiating an encryption protocol and completing an HTTPS handshake. Further, the method includes following the setup of between 100,000 HTTPS sessions and 10,000,000 HTTPS sessions, conducting a stress test including combining payload data and header information without using the negotiated encryption.
    Type: Application
    Filed: July 19, 2021
    Publication date: January 6, 2022
    Applicant: Spirent Communications, Inc.
    Inventors: Kevin CANADY, Richard WANK, Xiaohua WU, Chunsheng Li
  • Publication number: 20210220781
    Abstract: A sparkling water maker capable of automatically controlling gas inflow includes a gas cylinder, a gas cylinder connector mounted on the gas cylinder, a bottle, and a bottle connector mounted on the bottle. A gas guide tube is connected between the gas cylinder connector and the bottle connector. A compressed gas in the gas cylinder is delivered to the bottle through the gas guide tube. The gas guide tube includes a first gas guide tube connected to the gas cylinder connector and a second gas guide tube connected to the bottle connector. A valve is connected between the first gas guide tube and the second gas guide tube. The valve is configured to block a flow passage between the first gas guide tube and the second gas guide tube.
    Type: Application
    Filed: July 15, 2020
    Publication date: July 22, 2021
    Inventors: Xiaohua Wu, Ping Wang
  • Patent number: 11070451
    Abstract: The technology disclosed provides a method of testing handling of HTTPS sessions of a plurality of clients with a plurality of servers by a switching, bridging or routing device (i.e., a DUT), where the testing is conducted by a test system coupled to ports on the DUT. The method includes using client state machines running on at least four processor cores, communicating through the DUT with server state machines running on at least four additional processor cores. The method also includes, for each connection between a client represented by a client state machine and a server represented by a server state machine, setting up an HTTPS session by negotiating an encryption protocol and completing an HTTPS handshake. Further, the method includes following the setup of between 100,000 HTTPS sessions and 10,000,000 HTTPS sessions, conducting a stress test including combining payload data and header information without using the negotiated encryption.
    Type: Grant
    Filed: December 11, 2017
    Date of Patent: July 20, 2021
    Assignee: Spirent Communications, Inc.
    Inventors: Kevin Canady, Richard Wank, Xiaohua Wu, Chunsheng Li
  • Patent number: 10937158
    Abstract: An image volume formed by plural anatomical images each having plural image slices of different imaging modalities is segmented by a 2D convolutional neural network (CNN). An individual anatomical image is preprocessed to form a mixed-context image by incorporating selected image slices from two adjacent anatomical images without any estimated image slice. The 2D CNN utilizes side information on multi-modal context and 3D spatial context to enhance segmentation accuracy while avoiding segmentation performance degradation due to artifacts in the estimated image slice. The 2D CNN is realized by a BASKET-NET model having plural levels from a highest level to a lowest level. The number of channels in most multi-channel feature maps of a level decreases monotonically from the highest level to the lowest level, allowing the highest level to be rich in low-level feature details for assisting finer segmentation of the individual anatomical image.
    Type: Grant
    Filed: August 13, 2019
    Date of Patent: March 2, 2021
    Assignee: Hong Kong Applied Science and Technology Research Institute Company Limited
    Inventors: Xuejian He, Lu Wang, Xiaohua Wu
  • Publication number: 20210049756
    Abstract: An image volume formed by plural anatomical images each having plural image slices of different imaging modalities is segmented by a 2D convolutional neural network (CNN). An individual anatomical image is preprocessed to form a mixed-context image by incorporating selected image slices from two adjacent anatomical images without any estimated image slice. The 2D CNN utilizes side information on multi-modal context and 3D spatial context to enhance segmentation accuracy while avoiding segmentation performance degradation due to artifacts in the estimated image slice. The 2D CNN is realized by a BASKET-NET model having plural levels from a highest level to a lowest level. The number of channels in most multi-channel feature maps of a level decreases monotonically from the highest level to the lowest level, allowing the highest level to be rich in low-level feature details for assisting finer segmentation of the individual anatomical image.
    Type: Application
    Filed: August 13, 2019
    Publication date: February 18, 2021
    Inventors: Xuejian HE, Lu WANG, Xiaohua WU
  • Patent number: 10604474
    Abstract: A method for preparing a new crystalline form of ?-aminobutyric acid, including the steps of: S1: preparing a ?-aminobutyric acid solution at an initial concentration of 0.5-1.0 g/mL by adding crude ?-aminobutyric acid to water; adding an additive to the ?-aminobutyric acid solution, raising the temperature to 50-80° C., stirring to produce a clear solution; and S2: obtaining a suspension by evaporating water from the product of S1 under reduced pressure and at 50-80° C.; obtaining a wet product by filtering the suspension; drying the wet product to obtain the new crystalline form of ?-aminobutyric acid. The preparation method of the new crystalline form of ?-aminobutyric acid is simple, easy to operate, low in energy consumption, economical and environmentally friendly. It is suitable for large-scale industrial production.
    Type: Grant
    Filed: November 7, 2016
    Date of Patent: March 31, 2020
    Assignees: Nantong Licheng Biological Engineering Co., Ltd, Tianjin University
    Inventors: Junbo Gong, Kaifei Zhao, Haiyan Xi, Xiaohua Wu, Baohong Hou, Qiuxiang Yin, Jingkang Wang, Feng Jin, Shichao Du, Qinqing Gu, Shiping Tang
  • Publication number: 20190225574
    Abstract: A method for preparing a new crystalline form of ?-aminobutyric acid, including the steps of: S1: preparing a ?-aminobutyric acid solution at an initial concentration of 0.5-1.0 g/mL by adding crude ?-aminobutyric acid to water; adding an additive to the ?-aminobutyric acid solution, raising the temperature to 50-80° C., stirring to produce a clear solution; and S2: obtaining a suspension by evaporating water from the product of S1 under reduced pressure and at 50-80° C.; obtaining a wet product by filtering the suspension; drying the wet product to obtain the new crystalline form of ?-aminobutyric acid. The preparation method of the new crystalline form of ?-aminobutyric acid is simple, easy to operate, low in energy consumption, economical and environmentally friendly. It is suitable for large-scale industrial production.
    Type: Application
    Filed: November 7, 2016
    Publication date: July 25, 2019
    Inventors: Junbo Gong, Kaifei Zhao, Haiyan Xi, Xiaohua Wu, Baohong Hou, Qiuxiang Yin, Jingkang Wang, Feng Jin, Shichao Du, Qinqing Gu, Shiping Tang
  • Publication number: 20190182129
    Abstract: The technology disclosed provides a method of testing handling of HTTPS sessions of a plurality of clients with a plurality of servers by a switching, bridging or routing device (i.e., a DUT), where the testing is conducted by a test system coupled to ports on the DUT. The method includes using client state machines running on at least four processor cores, communicating through the DUT with server state machines running on at least four additional processor cores. The method also includes, for each connection between a client represented by a client state machine and a server represented by a server state machine, setting up an HTTPS session by negotiating an encryption protocol and completing an HTTPS handshake. Further, the method includes following the setup of between 100,000 HTTPS sessions and 10,000,000 HTTPS sessions, conducting a stress test including combining payload data and header information without using the negotiated encryption.
    Type: Application
    Filed: December 11, 2017
    Publication date: June 13, 2019
    Applicant: Spirent Communications, Inc.
    Inventors: Kevin Canady, Richard Wank, Xiaohua Wu, Chunsheng Li
  • Patent number: 10221168
    Abstract: The present invention provides compounds that can enhance functional O-mannosylation of proteins including alpha-dystroglycan. Also provided are methods of preparation of the compounds defined by the formula I. Also provided are the methods of using the compounds or the pharmaceutical acceptable salts or prodrugs thereof in treating and preventing subjects suffering from the diseases including muscular dystrophies and cancers.
    Type: Grant
    Filed: February 16, 2016
    Date of Patent: March 5, 2019
    Inventor: Xiaohua Wu
  • Patent number: 10108845
    Abstract: Using multiple imaging modes in whole slide image screening is potentially useful to reduce false positives. To use multiple imaging modes, a method for locating anomalies on a medical sample from an image thereof uses an anomaly-detection process that comprises using plural base classifiers individually to classify an object-of-interest suspected to be an anomaly. Each base classifier respectively extracts features of the object-of-interest and generates, according to the extracted features, a score indicating a likelihood of the object-of-interest being anomalous. The anomaly-detection process further comprises using an aggregate classifier to combine the scores generated by the base classifiers to determine whether the object-of-interest is the anomaly.
    Type: Grant
    Filed: March 2, 2017
    Date of Patent: October 23, 2018
    Assignee: Hong Kong Applied Science and Technology Research Institute Company Limited
    Inventors: Xiaohua Wu, Yan Nei Law
  • Patent number: 10083582
    Abstract: A data collection and processing apparatus with anti-theft function, a system using the apparatus and a data collection and processing method thereof are provided. The method includes the steps of: collecting relevant information regarding at least one targeted object, wherein the relevant information includes status information, operational information, environmental information of the targeted object, and user information of an owner or user of the targeted object; and performing an alarm when detecting that the targeted object is not under a normal status. The data collection and processing apparatus includes a transducer module, a master control module and an alarm and data processing module, which may form a local network connection or a distributed data processing network. In addition to performing anti-theft function, the present invention is capable of collecting various relevant information of the protected object.
    Type: Grant
    Filed: March 4, 2014
    Date of Patent: September 25, 2018
    Assignees: QUASION INC.
    Inventors: Xiaohua Wu, Ziyue Ouyang
  • Publication number: 20180253589
    Abstract: Using multiple imaging modes in whole slide image screening is potentially useful to reduce false positives. To use multiple imaging modes, a method for locating anomalies on a medical sample from an image thereof uses an anomaly-detection process that comprises using plural base classifiers individually to classify an object-of-interest suspected to be an anomaly. Each base classifier respectively extracts features of the object-of-interest and generates, according to the extracted features, a score indicating a likelihood of the object-of-interest being anomalous. The anomaly-detection process further comprises using an aggregate classifier to combine the scores generated by the base classifiers to determine whether the object-of-interest is the anomaly.
    Type: Application
    Filed: March 2, 2017
    Publication date: September 6, 2018
    Inventors: Xiaohua WU, Yan Nei LAW
  • Patent number: D1043690
    Type: Grant
    Filed: October 25, 2022
    Date of Patent: September 24, 2024
    Assignee: SHENZHEN XINJULUN ELECTRONICS CO., LTD.
    Inventor: Xiaohua Wu