Abstract: Provided are an anti-OX40 antibody, and a pharmaceutical composition and application thereof. The anti-OX40 antibody or an antigen-binding fragment and pharmaceutical composition thereof can be used for treating a T cell-related disease.

Abstract: In one embodiment, a method includes accessing a document, identifying one or more noun phrases in the document by performing a pre-processing on the accessed document, generating, for each identified noun phrase, a list of candidate entities corresponding to the noun phrase, wherein the list of candidate entities is looked up in an entity index using the noun phrase, computing, for each candidate entity corresponding to each identified noun phrase, a confidence score that the noun phrase is intended to reference the candidate entity by analyzing the accessed document by a machine learning model, constructing a pool of mention-entity pairs for the accessed document, filtering the pool of mention-entity pairs by removing each mention-entity pair from the pool based on their computed confidence scores, and storing the post-filtered pool of mention-entity pairs in a data store in association with the accessed document.

Abstract: In one embodiment, a social-networking system may receive, from a client system of a first user of the online social network, an indication that the first user is at a first geographic location, and determine that the first user is traveling based on the first user being at the first geographical location. The social-networking system may then identify one or more second geographic locations within a threshold distance from the first geographic location, the second geographic locations being determined based on a travel-recommendation model. The social-networking system may determine one or more itinerary constraints associated with the first user, generate a travel itinerary for the first user based on the first geographic location, the second geographic locations, and the itinerary constraints associated with the first user. The social-networking system may then send, to the client system of the first user, the travel itinerary for display to the first user.

Abstract: In one embodiment, a social-networking system may receive, from a client system of a first user of the online social network, an indication that the first user is accessing a travel-recommendation interface, receive an indication of a first geographic location, and identify one or more second geographic locations within a threshold distance from the first geographic location, the one or more second geographic locations being determined based on a travel-recommendation model associated with the first user. The social-networking system may generate one or more travel recommendations comprising at least one of the identified one or more second geographic locations, and send, to the client system of the first user, instructions for presenting the travel-recommendation interface, wherein the travel-recommendation interface comprises a map labeling one or more of the second geographic locations representing the travel recommendations.

Abstract: In one embodiment, a social-networking system may receive, from a client system of a first user of the online social network, an indication that the first user is accessing a travel-recommendation interface, receive an indication of a first geographic location, and identify one or more second geographic locations within a threshold distance from the first geographic location, the one or more second geographic locations being determined based on a travel-recommendation model associated with the first user. The social-networking system may generate one or more travel recommendations comprising at least one of the identified one or more second geographic locations, and send, to the client system of the first user, instructions for presenting the travel-recommendation interface, wherein the travel-recommendation interface comprises a map labeling one or more of the second geographic locations representing the travel recommendations.

Abstract: In one embodiment, a social-networking system may receive, from a client system of a first user of an online social network, an indication that the first user is traveling to a first geographic location, and identify one or more second geographic locations within a threshold distance from the first geographic location. The second geographic locations may be determined based on a travel-recommendation model. The travel-recommendation model may include aggregated user information from the online social network associated with the first user and aggregated travel information from the online social network associated with one or more second users of the online social network who have traveled to the first geographic location. The social-networking system may generate travel recommendations based on the identified second geographic locations, and then send, to the client system of the first user, one or more of the travel recommendations for display to the first user.

Abstract: In one embodiment, a social-networking system may receive, from a client system of a first user of the online social network, an indication that the first user is at a first geographic location, and determine that the first user is traveling based on the first user being at the first geographical location. The social-networking system may then identify one or more second geographic locations within a threshold distance from the first geographic location, the second geographic locations being determined based on a travel-recommendation model. The social-networking system may determine one or more itinerary constraints associated with the first user, generate a travel itinerary for the first user based on the first geographic location, the second geographic locations, and the itinerary constraints associated with the first user. The social-networking system may then send, to the client system of the first user, the travel itinerary for display to the first user.

Abstract: In one embodiment, a social-networking system may receive, from a client system of a first user of an online social network, an indication that the first user is traveling to a first geographic location, and identify one or more second geographic locations within a threshold distance from the first geographic location. The second geographic locations may be determined based on a travel-recommendation model. The travel-recommendation model may include aggregated user information from the online social network associated with the first user and aggregated travel information from the online social network associated with one or more second users of the online social network who have traveled to the first geographic location. The social-networking system may generate travel recommendations based on the identified second geographic locations, and then send, to the client system of the first user, one or more of the travel recommendations for display to the first user.