Abstract: Involved is an isolated antigen binding protein, being capable of binding CCR8 derived from a primate animal. Further involved are a pharmaceutical composition comprising the antigen binding protein, and an application of the antigen binding protein and/or the pharmaceutical composition in the prevention and/or treatment of a tumor or a cancer.

Abstract: A drilling device for geotechnical engineering investigation is provided, including an outer supporting ring seat, where a center of the outer supporting ring seat is rotatably connected with a middle supporting ring seat through a first supporting shaft rod; a center of the middle supporting ring seat is rotatably connected with an inner supporting ring seat through a second supporting shaft rod; the first supporting shaft rod and the second supporting shaft rod are vertically crossed; a second rotating motor is fixedly installed at one end of the first supporting shaft rod on an outer surface of the outer supporting ring seat; a pow output end of the second rotating motor is fixedly connected with the first supporting shaft rod, an other end of the first supporting shaft rod is provided with a first locking mechanism for position limitation.