Abstract: The present invention relates to a compound of formula (I), or a stereoisomer thereof, or a pharmaceutically acceptable salt thereof, and a use thereof in the preparation of a drug for treating diseases related to WEE1 activity.

Abstract: An X-ray imaging system using multiple pulsed X-ray sources in motion to perform high efficient and ultrafast 3D radiography is presented. There are multiple pulsed X-ray sources mounted on a structure in motion to form an array of sources. The multiple X-ray sources move simultaneously relative to an object on a pre-defined arc track at a constant speed as a group. Each individual X-ray source can also move rapidly around its static position in a small distance. When an X-ray source has a speed that is equal to group speed but with opposite moving direction, the X-ray source and X-ray flat panel detector are activated through an external exposure control unit so that source stay momentarily standstill. It results in much reduced source travel distance for each X-ray source. 3D scan can cover much wider sweep angle in much shorter time and image analysis can also be done in real-time.

Abstract: A glove includes: first palm pieces at fingertips of the glove and rear side pieces at the fingertips of the glove; the first palm piece and the rear side piece are integrally formed; each of the first palm piece and the rear side piece is sewn together at one end of their respective finger parts to form a three-dimensional structure, seams between the first palm pieces and the rear side pieces are provided on nails or on backs of fingers. The present disclosure includes a complete piece that fully encloses the fingertips formed integrally by the first palm piece and the rear side piece, and makes the sewn part of the first palm piece and the rear side piece from the fingertips to the back of the fingers.

Abstract: An optical or optoelectronic transceiver and methods of making the same are disclosed. The transceiver comprises a connector configured to receive an optical fiber array, a filter that is (i) configured to reflect first optical signals having a first wavelength and (ii) transparent to second optical signals having a second wavelength, wherein each of the first and second optical signals independently has an optical path to or from the optical fiber array, a mirror in the optical path of the second optical signals configured to reflect the second optical signals, a plurality of photodiodes configured to receive a subset of the first and/or second optical signals and generate a corresponding plurality of received electrical signals therefrom, and a plurality of laser diodes configured to transmit a remainder of the first and/or second optical signals from a corresponding plurality of transmitted electrical signals.

Abstract: A glove includes: first palm pieces at fingertips of the glove and rear side pieces at the fingertips of the glove; the first palm piece and the rear side piece are integrally formed; each of the first palm piece and the rear side piece is sewn together at one end of their respective finger parts to form a three-dimensional structure, seams between the first palm pieces and the rear side pieces are provided on nails or on backs of fingers. The present disclosure includes a complete piece that fully encloses the fingertips formed integrally by the first palm piece and the rear side piece, and makes the sewn part of the first palm piece and the rear side piece from the fingertips to the back of the fingers.

Abstract: An X-ray imaging system using multiple pulsed X-ray sources in motion to perform high efficient and ultrafast 3D radiography is presented. There are multiple pulsed X-ray sources mounted on a structure in motion to form an array of sources. The multiple X-ray sources move simultaneously relative to an object on a pre-defined arc track at a constant speed as a group. Each individual X-ray source can also move rapidly around its static position in a small distance. When an X-ray source has a speed that is equal to group speed but with opposite moving direction, the X-ray source and X-ray flat panel detector are activated through an external exposure control unit so that source stay momentarily standstill. It results in much reduced source travel distance for each X-ray source. 3D scan can cover much wider sweep angle in much shorter time and image analysis can also be done in real-time.

Abstract: An X-ray imaging system using multiple pulsed X-ray sources in motion to perform high efficient and ultrafast 3D radiography is presented. There are multiple pulsed X-ray sources mounted on a structure in motion to form an array of sources. The multiple X-ray sources move simultaneously relative to an object on a pre-defined arc track at a constant speed as a group. Each individual X-ray source can also move rapidly around its static position in a small distance. When an X-ray source has a speed that is equal to group speed but with opposite moving direction, the X-ray source and X-ray flat panel detector are activated through an external exposure control unit so that source stay momentarily standstill. It results in much reduced source travel distance for each X-ray source. 3D scan can cover much wider sweep angle in much shorter time and image analysis can also be done in real-time.

Abstract: An optical or optoelectronic transceiver and methods of making the same are disclosed. The transceiver comprises a connector configured to receive an optical fiber array, a filter that is (i) configured to reflect first optical signals having a first wavelength and (ii) transparent to second optical signals having a second wavelength, wherein each of the first and second optical signals independently has an optical path to or from the optical fiber array, a mirror in the optical path of the second optical signals configured to reflect the second optical signals, a plurality of photodiodes configured to receive a subset of the first and/or second optical signals and generate a corresponding plurality of received electrical signals therefrom, and a plurality of laser diodes configured to transmit a remainder of the first and/or second optical signals from a corresponding plurality of transmitted electrical signals.

Abstract: An X-ray imaging system using multiple pulsed X-ray sources in motion to perform high efficient and ultrafast 3D radiography is presented. There are multiple pulsed X-ray sources mounted on a structure in motion to form an array of sources. The multiple X-ray sources move simultaneously relative to an object on a pre-defined arc track at a constant speed as a group. Each individual X-ray source can also move rapidly around its static position in a small distance. When an X-ray source has a speed that is equal to group speed but with opposite moving direction, the X-ray source and X-ray flat panel detector are activated through an external exposure control unit so that source stay momentarily standstill. It results in much reduced source travel distance for each X-ray source. 3D scan can cover much wider sweep angle in much shorter time and image analysis can also be done in real-time.

Abstract: A bidirectional optical subassembly, an optical transceiver including the same, and methods of making and using the same are disclosed. The optical subassembly includes a photodiode configured to receive an incoming optical signal, a transmitter configured to transmit an outgoing optical signal, and a passive optical signal processing unit including a filter and a mirror. The filter is at a first predetermined angle relative to an optical path of the outgoing optical signal and is configured to (i) reflect one of the outgoing optical signal and the incoming optical signal and (ii) allow the other of the outgoing optical signal and the incoming optical signal to pass through. The mirror is configured to reflect the one of the outgoing optical signal and the incoming optical signal at a second predetermined angle. The first predetermined angle is adapted to reduce filter insertion losses.

Abstract: A bidirectional optical subassembly, an optical transceiver including the same, and methods of making and using the same are disclosed. The optical subassembly includes a photodiode configured to receive an incoming optical signal, a transmitter configured to transmit an outgoing optical signal, and a passive optical signal processing unit including a filter and a mirror. The filter is at a first predetermined angle relative to an optical path of the outgoing optical signal and is configured to (i) reflect one of the outgoing optical signal and the incoming optical signal and (ii) allow the other of the outgoing optical signal and the incoming optical signal to pass through. The mirror is configured to reflect the one of the outgoing optical signal and the incoming optical signal at a second predetermined angle. The first predetermined angle is adapted to reduce filter insertion losses.

Abstract: An integrated lens with integrated functional optical surfaces for use in optical communication is disclosed. The integrated lens includes first and second cavities and a fiber adapter. The device also includes integrated first and second lenses. The first cavity houses one or more optical transmitting and/or receiving devices. The second cavity has a first optical surface and an optional second optical surface. The fiber adapter has the second lens. The integrated lens enables a small size, a light weight, high coupling and a high transmission efficiency, and can be produced by injection molding using a single mold. The integrated lens is applicable to optical signal coupling, fiber connections, optical modules, and optical or optoelectronic communication.

Abstract: An integrated lens with integrated functional optical surfaces for use in optical communication is disclosed. The integrated lens includes first and second cavities and a fiber adapter. The device also includes integrated first and second lenses. The first cavity houses one or more optical transmitting and/or receiving devices. The second cavity has a first optical surface and an optional second optical surface. The fiber adapter has the second lens. The integrated lens enables a small size, a light weight, high coupling and a high transmission efficiency, and can be produced by injection molding using a single mold. The integrated lens is applicable to optical signal coupling, fiber connections, optical modules, and optical or optoelectronic communication.

Abstract: A high speed optical module, and in particular, a multi-channel, single-mode, parallel transmission optical module in the field of optical communication is disclosed. The optical module includes a chassis, a first transmitter optical subassembly (TOSA), a second transmitter optical subassembly (TOSA), a third transmitter optical subassembly (TOSA), a fourth transmitter optical subassembly (TOSA) and a MT fiber connector. The TOSA may be a TO-38 TOSA of a 10 G DFB chip or FP chip. With single-mode communication, the optical module provides a transmission distance over 10 kilometers. In addition, to make coupling single-mode fibers easier, a twelve-core MT fiber connector is employed, wherein four fiber connectors are respectively connected to LC standard fiber stubs and the outputs of the TOSAs accordingly. Thus, the optical module further provides high speed and long-distance transmission, large capacity, small volume, and light weight and can be broadly applied to high speed optical communications.

Abstract: An integrated lens with integrated functional optical surfaces for use in optical communication is disclosed. The integrated lens includes first and second cavities and a fiber adapter. The device also includes integrated first and second lenses. The first cavity houses one or more optical transmitting and/or receiving devices. The second cavity has a first optical surface and an optional second optical surface. The fiber adapter has the second lens. The integrated lens enables a small size, a light weight, high coupling and a high transmission efficiency, and can be produced by injection molding using a single mold. The integrated lens is applicable to optical signal coupling, fiber connections, optical modules, and optical or optoelectronic communication.

Abstract: An integrated lens with integrated functional optical surfaces for use in optical communication is disclosed. The integrated lens includes first and second cavities and a fiber adapter. The device also includes integrated first and second lenses. The first cavity houses one or more optical transmitting and/or receiving devices. The second cavity has a first optical surface and an optional second optical surface. The fiber adapter has the second lens. The integrated lens enables a small size, a light weight, high coupling and a high transmission efficiency, and can be produced by injection molding using a single mold. The integrated lens is applicable to optical signal coupling, fiber connections, optical modules, and optical or optoelectronic communication.

Abstract: A high speed optical module, and in particular, a multi-channel, single-mode, parallel transmission optical module in the field of optical communication is disclosed. The optical module includes a chassis, a first transmitter optical subassembly (TOSA), a second transmitter optical subassembly (TOSA), a third transmitter optical subassembly (TOSA), a fourth transmitter optical subassembly (TOSA) and a MT fiber connector. The TOSA may be a TO-38 TOSA of a 10 G DFB chip or FP chip. With single-mode communication, the optical module provides a transmission distance over 10 kilometers. In addition, to make coupling single-mode fibers easier, a twelve-core MT fiber connector is employed, wherein four fiber connectors are respectively connected to LC standard fiber stubs and the outputs of the TOSAs accordingly. Thus, the optical module further provides high speed and long-distance transmission, large capacity, small volume, and light weight and can be broadly applied to high speed optical communications.

Abstract: A sensor for detecting the presence of predetermined chemical/biological molecules, the sensor having a MOSFET device (2, 3, 6, 7, 9, 10, 12, 13), the gate having an array of nanoscale fingers (6,7), and on fingers or in spaces between the fingers, chemical/biological receptor molecules (15) suitable for selectively binding with the predetermined chemical/biological molecules, the sensor also having circuitry (4, 5, 11, 12) for measuring a change in a change in drain current of the FET caused by the predetermined chemical/biological molecules becoming bound to the receptor molecules. Sensitivity and reliability can be increased compared to capacitive sensors.